| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Infertility, Male | D007248 | 11 associated lipids |
| Varicocele | D014646 | 4 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hsu AF et al. | Characterization of soybean lipoxygenase immobilized in cross-linked phyllosilicates. | 1998 | Biotechnol. Appl. Biochem. | pmid:9693089 |
| Goodrich-Tanrikulu M et al. | Changes in fatty acid composition of Neurospora crassa accompany sexual development and ascospore germination. | 1998 | Microbiology (Reading, Engl.) | pmid:9695905 |
| Yamaguchi H et al. | High transepidermal water loss induces fatty acid synthesis and cutaneous fatty acid-binding protein expression in rat skin. | 1998 | J. Dermatol. Sci. | pmid:9697049 |
| Pöge AP et al. | Long-chain polyunsaturated fatty acids in plasma and erythrocyte membrane lipids of children with phenylketonuria after controlled linoleic acid intake. | 1998 | J. Inherit. Metab. Dis. | pmid:9700594 |
| Mazhul' VM and Shcherbin DG | [Low temperature phosphorescence of lipid peroxidation products]. | 1998 May-Jun | Biofizika | pmid:9702337 |
| KmonÃcková E et al. | Differences in heart phospholipids in two inbred rat strains differing in sensitivity to the development of heart lesions. | 1998 | Physiol Res | pmid:9706993 |
| Ondrias K et al. | Antioxidant and pro-oxidant effects of epinephrine and isoprenaline on peroxidation of LDL and lipid liposomes. | 1998 | Physiol Res | pmid:9706995 |
| Butovich IA et al. | Oxidation of linoleyl alcohol by potato tuber lipoxygenase: possible mechanism and the role of carboxylic group in substrate binding. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9712698 |
| Konrad SD et al. | Use of deuterium oxide to measure de novo fatty acid synthesis in normal subjects consuming different dietary fatty acid composition1. | 1998 | Biochim. Biophys. Acta | pmid:9714781 |
| Ryu SB and Wang X | Increase in free linolenic and linoleic acids associated with phospholipase D-mediated hydrolysis of phospholipids in wounded castor bean leaves. | 1998 | Biochim. Biophys. Acta | pmid:9714802 |
| Osada K et al. | Dietary oxidized cholesterol modulates cholesterol metabolism and linoleic acid desaturation in rats fed high-cholesterol diets. | 1998 | Lipids | pmid:9727605 |
| West DB et al. | Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. | 1998 | Am. J. Physiol. | pmid:9728060 |
| Wilson TA et al. | Soy lecithin reduces plasma lipoprotein cholesterol and early atherogenesis in hypercholesterolemic monkeys and hamsters: beyond linoleate. | 1998 | Atherosclerosis | pmid:9733225 |
| Sentex E et al. | Is the cytoprotective effect of trimetazidine associated with lipid metabolism? | 1998 | Am. J. Cardiol. | pmid:9737482 |
| Schwinn J et al. | Thiyl radical-induced cis/trans-isomerization of methyl linoleate in methanol and of linoleic acid residues in liposomes. | 1998 | Int. J. Radiat. Biol. | pmid:9737538 |
| Fidler N et al. | Effects of human milk pasteurization and sterilization on available fat content and fatty acid composition. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9740204 |
| Liu JH et al. | Inhibitory effects of Angelica pubescens f. biserrata on 5-lipoxygenase and cyclooxygenase. | 1998 | Planta Med. | pmid:9741298 |
| Rodriguez A et al. | Delta6- and delta5-desaturase activities in the human fetal liver: kinetic aspects. | 1998 | J. Lipid Res. | pmid:9741695 |
| Sluse FE et al. | Free fatty acids regulate the uncoupling protein and alternative oxidase activities in plant mitochondria. | 1998 | FEBS Lett. | pmid:9744802 |
| Romijn D et al. | A linoleic acid enriched diet increases serum cholesterol esterification by lecithin:cholesterol acyltransferase in meal-fed rats. | 1998 | Ann. Nutr. Metab. | pmid:9745111 |
| Berdeaux O et al. | In vitro desaturation or elongation of monotrans isomers of linoleic acid by rat liver microsomes. | 1998 | Mol. Cell. Biochem. | pmid:9746207 |
| Kanazawa K and Ashida H | Catabolic fate of dietary trilinoleoylglycerol hydroperoxides in rat gastrointestines. | 1998 | Biochim. Biophys. Acta | pmid:9748647 |
| Kanazawa K and Ashida H | Dietary hydroperoxides of linoleic acid decompose to aldehydes in stomach before being absorbed into the body. | 1998 | Biochim. Biophys. Acta | pmid:9748650 |
| Ando H et al. | Linoleic acid and alpha-linolenic acid lightens ultraviolet-induced hyperpigmentation of the skin. | 1998 | Arch. Dermatol. Res. | pmid:9749992 |
| Kuratko CN and Constante BJ | Linoleic acid and tumor necrosis factor-alpha increase manganese superoxide dismutase activity in intestinal cells. | 1998 | Cancer Lett. | pmid:9751273 |
| Benito S et al. | Phospholipid fatty acid composition affects enzymatic antioxidant defenses in cultured Swiss 3T3 fibroblasts. | 1997 Oct-Dec | Redox Rep. | pmid:9754326 |
| Spalinger JH et al. | Uptake and metabolism of structured triglyceride by Caco-2 cells: reversal of essential fatty acid deficiency. | 1998 | Am. J. Physiol. | pmid:9756493 |
| Wijewickreme AN and Kitts DD | Modulation of metal-induced cytotoxicity by maillard reaction products isolated from coffee brew. | 1998 | J. Toxicol. Environ. Health Part A | pmid:9761134 |
| Obukowicz MG et al. | Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9765335 |
| Iwamoto S et al. | Effects of fatty acids on liver metastasis of ACL-15 rat colon cancer cells. | 1998 | Nutr Cancer | pmid:9770727 |
| Ober MD and Hart CM | Attenuation of oxidant-mediated endothelial cell injury with docosahexaenoic acid: the role of intracellular iron. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774176 |
| Wander RC et al. | Influence of long-chain polyunsaturated fatty acids on oxidation of low density lipoprotein. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774178 |
| Hu ZY et al. | cAMP inhibits linoleic acid-induced growth by antagonizing p27(kip1) depletion, but not interfering with the extracellular signal-regulated kinase or AP-1 activities. | 1998 | Biochim. Biophys. Acta | pmid:9784625 |
| Schmuck A et al. | Fatty acid nutriture in hospitalized elderly women. | 1998 | J Am Coll Nutr | pmid:9791841 |
| Turpeinen AM et al. | Replacement of dietary saturated by unsaturated fatty acids: effects of platelet protein kinase C activity, urinary content of 2,3-dinor-TXB2 and in vitro platelet aggregation in healthy man. | 1998 | Thromb. Haemost. | pmid:9798986 |
| Bretillon L et al. | Desaturation and chain elongation of [1-14C]mono-trans isomers of linoleic and alpha-linolenic acids in perfused rat liver. | 1998 | J. Lipid Res. | pmid:9799809 |
| Cunnane SC et al. | Substantial carbon recycling from linoleate into products of de novo lipogenesis occurs in rat liver even under conditions of extreme dietary linoleate deficiency. | 1998 | J. Lipid Res. | pmid:9799813 |
| de Deckere EA et al. | Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. | 1998 | Eur J Clin Nutr | pmid:9805223 |
| Hauville C et al. | Determination of the yield of radiation-induced peroxidation of sodium linoleate in aqueous monomeric and micellar solutions. | 1998 | Radiat. Res. | pmid:9806603 |
| Masia A et al. | Enrichment with a polyunsaturated fatty acid enhances the survival of Saccharomyces cerevisiae in the presence of tributyltin. | 1998 | FEMS Microbiol. Lett. | pmid:9809434 |
| Broun P et al. | Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. | 1998 | Science | pmid:9812895 |
| Fukuda N et al. | Effect of emeriamine, an inhibitor of fatty acid oxidation, on metabolic fate of a geometrical isomer of linoleic acid in perfused rat liver. | 1998 | J. Nutr. Sci. Vitaminol. | pmid:9819713 |
| Morita Y et al. | Involvement of lipid peroxidation in free fatty acid-induced isolated rat pancreatic acinar cell injury. | 1998 | Pancreas | pmid:9821180 |
| Sehat N et al. | Identification of conjugated linoleic acid isomers in cheese by gas chromatography, silver ion high performance liquid chromatography and mass spectral reconstructed ion profiles. Comparison of chromatographic elution sequences. | 1998 | Lipids | pmid:9832075 |
| Gu JY et al. | Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836427 |
| Iwase H et al. | Calcium is required for quasi-lipoxygenase activity of hemoproteins. | 1998 | Free Radic. Biol. Med. | pmid:9840740 |
| Phifer CB and Berthoud HR | Duodenal nutrient infusions differentially affect sham feeding and Fos expression in rat brain stem. | 1998 | Am. J. Physiol. | pmid:9841547 |
| Turpeinen AM et al. | A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844997 |
| Oyama Y et al. | Protective actions of 5'-n-alkylated curcumins on living cells suffering from oxidative stress. | 1998 | Eur. J. Pharmacol. | pmid:9845274 |
| Nestel PJ et al. | Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations. | 1998 | Am. J. Clin. Nutr. | pmid:9846846 |
| Chobot'ko HM | [Effects of modifications of lipoproteins by water soluble forms of lineoleic-hydroxamic acid on biochemical markers of development of atherosclerosis]. | 1998 Jul-Aug | Ukr. Biokhim. Zh. | pmid:9848203 |
| Louw L et al. | Comparison of the fatty acid compositions in intraepithelial and infiltrating lesions of the cervix: part I, total fatty acid profiles. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9849650 |
| Wagner K et al. | Research note: effect of duodenal--infused unsaturated fatty acids on dairy milk composition. | 1998 | Arch Tierernahr | pmid:9850802 |
| Spiteller G | Linoleic acid peroxidation--the dominant lipid peroxidation process in low density lipoprotein--and its relationship to chronic diseases. | 1998 | Chem. Phys. Lipids | pmid:9853364 |
| Jarmuszkiewicz W et al. | Linoleic acid-induced activity of plant uncoupling mitochondrial protein in purified tomato fruit mitochondria during resting, phosphorylating, and progressively uncoupled respiration. | 1998 | J. Biol. Chem. | pmid:9857016 |
| Davidson BC et al. | The influence of fatty acids on normal and transformed human liver cells in culture. | 1998 Sep-Oct | Anticancer Res. | pmid:9858936 |
| Hudson JA et al. | Hydration of linoleic acid by bacteria isolated from ruminants. | 1998 | FEMS Microbiol. Lett. | pmid:9868771 |
| Blaauwwiekel EE et al. | Apolipoprotein E genotype is a determinant of low-density lipoprotein cholesterol and of its response to a low-cholesterol diet in Type 1 diabetic patients with elevated urinary albumin excretion. | 1998 | Diabet. Med. | pmid:9868977 |
| Kim EJ et al. | Development of a serum-free medium for the production of humanized antibody from Chinese hamster ovary cells using a statistical design. | 1998 Nov-Dec | In Vitro Cell. Dev. Biol. Anim. | pmid:9870524 |
| Palombo JD et al. | Metabolism of dietary alpha-linolenic acid vs. eicosapentaenoic acid in rat immune cell phospholipids during endotoxemia. | 1998 | Lipids | pmid:9870905 |
| Akeo K and Hiramitsu T | Changes in lipid peroxide level in retinal pigment epithelial cells in vitro upon addition of linoleic acids or linoleic acid hydroperoxides under varying concentrations of oxygen. | 1998 | Pigment Cell Res. | pmid:9877104 |
| Matsuba S et al. | Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888206 |
| Tsimikas S et al. | LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:9888874 |
| Cook ME | Nutritional effects on vaccination. | 1999 | Adv Vet Med | pmid:9890009 |
| Hennig B et al. | Linoleic acid amplifies polychlorinated biphenyl-mediated dysfunction of endothelial cells. | 1999 | J. Biochem. Mol. Toxicol. | pmid:9890193 |
| O'Donnell VB et al. | Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion. | 1999 | Chem. Res. Toxicol. | pmid:9894022 |
| Mahfouz MM and Kummerow FA | Hydrogenated fat high in trans monoenes with an adequate level of linoleic acid has no effect on prostaglandin synthesis in rats. | 1999 | J. Nutr. | pmid:9915870 |
| Hayek MG et al. | Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. | 1999 | J. Nutr. | pmid:9915872 |
| Satory DL and Smith SB | Conjugated linoleic acid inhibits proliferation but stimulates lipid filling of murine 3T3-L1 preadipocytes. | 1999 | J. Nutr. | pmid:9915881 |
| Pohl CH et al. | Oxylipin formation in fungi: biotransformation of arachidonic acid to 3-hydroxy-5,8-tetradecadienoic acid by Mucor genevensis. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9918790 |
| Allman-Farinelli MA et al. | Comparison of the effects of two low fat diets with different alpha-linolenic:linoleic acid ratios on coagulation and fibrinolysis. | 1999 | Atherosclerosis | pmid:9920517 |
| Natella F et al. | Oxidative modification of human low-density lipoprotein by horseradish peroxidase in the absence of hydrogen peroxide. | 1998 | Free Radic. Res. | pmid:9925035 |
| Kalivianakis M et al. | Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. | 1999 | Am. J. Clin. Nutr. | pmid:9925134 |
| Began G et al. | Inhibition of lipoxygenase 1 by phosphatidylcholine micelles-bound curcumin. | 1998 | Lipids | pmid:9930409 |
| Chyb S et al. | Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. | 1999 | Nature | pmid:9930700 |
| Toborek M and Hennig B | The role of linoleic acid in endothelial cell gene expression. Relationship to atherosclerosis. | 1998 | Subcell. Biochem. | pmid:9932524 |
| Black PN | The prevalence of allergic disease and linoleic acid in the diet. | 1999 | J. Allergy Clin. Immunol. | pmid:9949330 |
| Rao MS et al. | Yield, protein, and oil quality of soybean genotypes selected for tofu production. | 1998 | Plant Foods Hum Nutr | pmid:9950085 |
| Zhou L and Nilsson A | Fasting increases tissue uptake and interconversion of plasma unesterified linoleic acid in guinea pigs. | 1999 | Biochim. Biophys. Acta | pmid:9989279 |
| Sasaki T et al. | Effects of dietary docosahexaenoic acid on surface molecules involved in T cell proliferation. | 1999 | Biochim. Biophys. Acta | pmid:9989281 |