Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Melanosis D008548 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Biliary Atresia D001656 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Varicocele D014646 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Choroidal Neovascularization D020256 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Kelavkar UP et al. Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging. 2000 Carcinogenesis pmid:11023533
Qian SY et al. EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. 2000 Free Radic. Biol. Med. pmid:11025200
Van de Velde M et al. Effects of lipids on the functional and metabolic recovery from global myocardial stunning in isolated rabbit hearts. 2000 Cardiovasc. Res. pmid:11033115
Meaney CM and O'Driscoll CM A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model. 2000 Int J Pharm pmid:11036226
Smith HL et al. Development of a serum-free system for the in vitro cultivation of Brugia malayi infective-stage larvae. 2000 Exp. Parasitol. pmid:11038308
French SJ et al. The effects of intestinal infusion of long-chain fatty acids on food intake in humans. 2000 Gastroenterology pmid:11040181
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Soriano CR et al. Cutaneous application of vegetable oil as a coadjutant in the nutritional management of preterm infants. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:11045835
Steinkamp G et al. Energy supplements rich in linoleic acid improve body weight and essential fatty acid status of cystic fibrosis patients. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:11045840
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Surai PF et al. Effect of long-term supplementation with arachidonic or docosahexaenoic acids on sperm production in the broiler chicken. 2000 J. Reprod. Fertil. pmid:11058441
Cunnane SC et al. Specific linoleate deficiency in the rat does not prevent substantial carbon recycling from [(14)C]linoleate into sterols. 2000 J. Lipid Res. pmid:11060350
Ferry DR et al. A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. 2000 Ann. Oncol. pmid:11061613
French P et al. Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets. 2000 J. Anim. Sci. pmid:11063308
Brynes AE et al. Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. 2000 Am. J. Clin. Nutr. pmid:11063437
Granot E et al. Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. 2000 Am. J. Clin. Nutr. pmid:11063450
Sauerwald TU et al. Polyunsaturated fatty acid supply with human milk. Physiological aspects and in vivo studies of metabolism. 2000 Adv. Exp. Med. Biol. pmid:11065079
Del Prado M et al. Contribution of dietary and newly formed arachidonic acid to milk secretion in women on low fat diets. 2000 Adv. Exp. Med. Biol. pmid:11065105
Lance A et al. 13C-linoleic acid oxidation and transfer into milk in lactating women with contrasting body mass index. 2000 Adv. Exp. Med. Biol. pmid:11065106
Cahoon EB et al. Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid. 2001 J. Biol. Chem. pmid:11067856