Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Glioma D005910 112 associated lipids
Glomerulonephritis D005921 35 associated lipids
Haemophilus Infections D006192 3 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heart Failure D006333 36 associated lipids
Hemolysis D006461 131 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperplasia D006965 34 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypertension D006973 115 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypertension, Renal D006977 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Groussard C et al. Free radical scavenging and antioxidant effects of lactate ion: an in vitro study. 2000 J. Appl. Physiol. pmid:10904049
Boué C et al. Trans fatty acids in adipose tissue of French women in relation to their dietary sources. 2000 Lipids pmid:10907791
O'Shea M et al. The effect of a conjugated dienoic derivative of linoleic acid on the in vitro growth of MCF-7 and SW480 human cancer cell lines. 1998 Biochem. Soc. Trans. pmid:10909819
Cantwell H et al. The effect of a conjugated linoleic acid on superoxide dismutase, catalase and glutathione peroxidase in oxidatively-challenged liver cells. 1998 Biochem. Soc. Trans. pmid:10909820
Wenger FA et al. Does alpha-linolenic acid in combination with linoleic acid influence liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters? 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10913224
Sakurada K et al. cis-9,10-Methylenehexadecanoic acid inhibits contractility and actomyosin ATPase activity of guinea pig myocardium. 2000 Biochem. Biophys. Res. Commun. pmid:10913372
Vanella A et al. L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. 2000 Cell Biol. Toxicol. pmid:10917565
Jones S et al. Isomers of conjugated linoleic acid (CLA) are incorporated into egg yolk lipids by CLA-fed laying hens. 2000 J. Nutr. pmid:10917915
Kamlage B et al. Linoleic acid conjugation by human intestinal microorganisms is inhibited by glucose and other substrates in vitro and in gnotobiotic rats. 2000 J. Nutr. pmid:10917922
Viola G et al. In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine. 2000 Farmaco pmid:10919085
Ip C et al. Induction of apoptosis by conjugated linoleic acid in cultured mammary tumor cells and premalignant lesions of the rat mammary gland. 2000 Cancer Epidemiol. Biomarkers Prev. pmid:10919739
Rosella O et al. Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro. 2000 J. Gastroenterol. Hepatol. pmid:10921416
Dilika F et al. Antibacterial activity of linoleic and oleic acids isolated from Helichrysum pedunculatum: a plant used during circumcision rites. 2000 Fitoterapia pmid:10925024
Wingler K et al. Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells. 2000 Gastroenterology pmid:10930377
Kotani A et al. Determination of plasma free fatty acids by high-performance liquid chromatography with electrochemical detection. 2000 Anal. Biochem. pmid:10933857
Zusman I et al. Transplacental effects of maternal feeding with high fat diets on lipid exchange and response of the splenic lymphoid system in mice offspring exposed to low doses of carcinogen. 2000 Int. J. Mol. Med. pmid:10934300
Fabbri AA et al. Early physiological and cytological events induced by wounding in potato tuber. 2000 J. Exp. Bot. pmid:10937703
Meilhac O et al. Lipid peroxides induce expression of catalase in cultured vascular cells. 2000 J. Lipid Res. pmid:10946007
Magsino CH et al. Nadolol inhibits reactive oxygen species generation by leukocytes and linoleic acid oxidation. 2000 Am. J. Cardiol. pmid:10946040
Yang M et al. Dietary conjugated linoleic acid protects against end stage disease of systemic lupus erythematosus in the NZB/W F1 mouse. 2000 Immunopharmacol Immunotoxicol pmid:10946824