Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Gänzle MG et al. | Resistance of Escherichia coli and Salmonella against nisin and curvacin A. | 1999 | Int. J. Food Microbiol. | pmid:10375133 |
Forster C et al. | Molecular analysis of a null mutant for pea (Pisum sativum L.) seed lipoxygenase-2. | 1999 | Plant Mol. Biol. | pmid:10380807 |
Akeo K et al. | Effects of fluorescent light on growth of bovine retinal pigment epithelial cells in vitro incubated with linoleic acid or linoleic acid hydroperoxide. | 1999 | Pigment Cell Res. | pmid:10385917 |
Parodi PW | Conjugated linoleic acid and other anticarcinogenic agents of bovine milk fat. | 1999 | J. Dairy Sci. | pmid:10386321 |
Greenberg D et al. | Differential satiating effects of fats in the small intestine of obesity-resistant and obesity-prone rats. | 1999 | Physiol. Behav. | pmid:10386906 |
Jiang J et al. | Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. | 1999 | Am. J. Clin. Nutr. | pmid:10393134 |
Jeppesen PB et al. | Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. | 1999 | Am. J. Clin. Nutr. | pmid:10393142 |
Su HM et al. | Linoleic acid kinetics and conversion to arachidonic acid in the pregnant and fetal baboon. | 1999 | J. Lipid Res. | pmid:10393215 |
Ando H et al. | Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis. | 1999 | J. Lipid Res. | pmid:10393216 |
Hidaka T et al. | Screening of microbial products modifying the action of leptin (obese gene product) by a biosensor. | 1999 | J. Antibiot. | pmid:10395281 |
Ingkaninan K et al. | Interference of linoleic acid fraction in some receptor binding assays. | 1999 | J. Nat. Prod. | pmid:10395519 |
Bousquet MP et al. | Enzymatic synthesis of unsaturated fatty acid glucoside esters for dermo-cosmetic applications. | 1999 | Biotechnol. Bioeng. | pmid:10397830 |
Andersen LF et al. | Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. | 1999 | Am. J. Epidemiol. | pmid:10400557 |
O'Donnell VB et al. | 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase. | 1999 | J. Biol. Chem. | pmid:10400618 |
Dontsov AE et al. | Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids. | 1999 | Free Radic. Biol. Med. | pmid:10401607 |
Ding XZ et al. | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10405349 |
Kim S et al. | C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts. | 1999 | Mol. Cell. Biol. | pmid:10409760 |
Sammon AM | Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10410386 |
Demmelmair H et al. | Comparison of bolus versus fractionated oral applications of [13C]-linoleic acid in humans. | 1999 | Eur. J. Clin. Invest. | pmid:10411666 |
Cunnane SC et al. | Magnetic resonance imaging-based balance analysis of linoleate utilization during weight loss in obese humans. | 1999 | Lipids | pmid:10419101 |
Belza K et al. | Carbon recycling from linoleate during severe dietary linoleate deficiency. | 1999 | Lipids | pmid:10419120 |
Babin F et al. | Suspicion of latent delta5-desaturase and peroxisomal beta-oxidation deficiency in elderly women over 75 years of age. | 1999 | Lipids | pmid:10419136 |
Calvo AM et al. | Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. | 1999 | Appl. Environ. Microbiol. | pmid:10427064 |
Yamasaki M et al. | Dietary effect of conjugated linoleic acid on lipid levels in white adipose tissue of Sprague-Dawley rats. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10427699 |
Rudel LL | Atherosclerosis and conjugated linoleic acid. | 1999 | Br. J. Nutr. | pmid:10434843 |
Ahn DU et al. | Effect of dietary conjugated linoleic acid on the quality characteristics of chicken eggs during refrigerated storage. | 1999 | Poult. Sci. | pmid:10438141 |
Jarmuszkiewicz W et al. | Identification and characterization of a protozoan uncoupling protein in Acanthamoeba castellanii. | 1999 | J. Biol. Chem. | pmid:10438491 |
Freese R et al. | Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females. | 1999 | Eur J Nutr | pmid:10443337 |
Beuerle T and Schwab W | Metabolic profile of linoleic acid in stored apples: formation of 13(R)-hydroxy-9(Z),11(E)-octadecadienoic acid. | 1999 | Lipids | pmid:10443970 |
Lundell KH et al. | Plasma metabolites after a lipid load in infants with congenital heart disease. | 1999 | Acta Paediatr. | pmid:10447129 |
Sammon AM | Dietary linoleic acid, immune inhibition and disease. | 1999 | Postgrad Med J | pmid:10448487 |
Lipkin M et al. | Dietary factors in human colorectal cancer. | 1999 | Annu. Rev. Nutr. | pmid:10448536 |
Nakano N et al. | Formation of 8,11,14-octadecatrienoic acid (18:3 n-4) from naturally occurring unique fatty acid, 9,12-hexadecadienoic acid (16:2 n-4), in animal cell cultures. | 1999 | J. Nutr. Sci. Vitaminol. | pmid:10450561 |
Kharchenko OV et al. | [Inhibitory effect of linoleyl-hydroxamic acid on the oxidation of linoleic acid by 12-lipoxygenase from porcine leukocytes]. | 1999 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:10457987 |
Butovich IA and Kharchenko OV | [Role of phospholipids in the regulation of activity of porcine leukocyte 12-lipoxygenase]. | 1999 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:10457988 |
Warnotte C et al. | Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. | 1999 | Mol. Cell. Endocrinol. | pmid:10459862 |
Helge JW et al. | Regular exercise modulates muscle membrane phospholipid profile in rats. | 1999 | J. Nutr. | pmid:10460197 |
Stan S et al. | Modulation of apo A-IV transcript levels and synthesis by n-3, n-6, and n-9 fatty acids in CACO-2 cells. | 1999 | J. Cell. Biochem. | pmid:10462706 |
O'Shea M et al. | Antioxidant enzyme defence responses of human MCF-7 and SW480 cancer cells to conjugated linoleic acid. | 1999 May-Jun | Anticancer Res. | pmid:10470140 |
Cunnane SC et al. | Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471127 |
Salem N et al. | In vivo conversion of linoleic acid to arachidonic acid in human adults. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471130 |
Park JY et al. | Role of hyperpolarization attained by linoleic acid in chick myoblast fusion. | 1999 | Exp. Cell Res. | pmid:10471316 |
Meek S et al. | Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A-subunit of PP2A. | 1999 | FEBS Lett. | pmid:10471836 |
Chamruspollert M and Sell JL | Transfer of dietary conjugated linoleic acid to egg yolks of chickens. | 1999 | Poult. Sci. | pmid:10472840 |
Lin MY and Yen CL | Reactive oxygen species and lipid peroxidation product-scavenging ability of yogurt organisms. | 1999 | J. Dairy Sci. | pmid:10480088 |
Kankaanpää P et al. | Dietary fatty acids and allergy. | 1999 | Ann. Med. | pmid:10480759 |
Precht D and Molkentin J | C18:1, C18:2 and C18:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids. | 1999 | Nahrung | pmid:10481820 |
Vicanová J et al. | Incorporation of linoleic acid by cultured human keratinocytes. | 1999 Jul-Aug | Arch. Dermatol. Res. | pmid:10482010 |
Sauer LA et al. | 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. | 1999 | Cancer Res. | pmid:10493526 |
Blask DE et al. | Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. | 1999 | Cancer Res. | pmid:10493527 |