Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Dermatitis, Seborrheic D012628 10 associated lipids
Retinoblastoma D012175 12 associated lipids
Retinal Degeneration D012162 9 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Refsum Disease D012035 19 associated lipids
Refractive Errors D012030 1 associated lipids
Pulmonary Edema D011654 23 associated lipids
Psoriasis D011565 47 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Proteinuria D011507 30 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Precancerous Conditions D011230 48 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
Pellagra D010383 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Ivan M et al. Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. 2013 Br. J. Nutr. pmid:22850225
Alvheim AR et al. Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice. 2013 Br. J. Nutr. pmid:22883314
Otte KB et al. Synthesis of 9-oxononanoic acid, a precursor for biopolymers. 2013 ChemSusChem pmid:23934656
Cheng G et al. Relative validity of a 3 d estimated food record in German toddlers. 2013 Public Health Nutr pmid:22874634
Emery JA et al. Δ-6 Desaturase substrate competition: dietary linoleic acid (18:2n-6) has only trivial effects on α-linolenic acid (18:3n-3) bioconversion in the teleost rainbow trout. 2013 PLoS ONE pmid:23460861
Suardíaz R et al. An insight into the regiospecificity of linoleic acid peroxidation catalyzed by mammalian 15-lipoxygenases. 2013 J Phys Chem B pmid:23496802
Cardoso S et al. UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. 2013 J. Bioenerg. Biomembr. pmid:23504111
Stamey Lanier J et al. Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. 2013 Lipids pmid:23504269
Shen W et al. Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice. 2013 J. Lipid Res. pmid:23401602
Saubeau G et al. Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. 2013 Plant Cell Rep. pmid:23479199
Godinot N et al. Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice. 2013 Neuroscience pmid:23831422
Lai MC et al. The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. 2013 J. Vet. Med. Sci. pmid:23832628
Bartók T et al. ESI-MS and MS/MS identification of the first ceramide analogues of fumonisin B₁ mycotoxin from a Fusarium verticillioides culture following RP-HPLC separation. 2013 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:23837460
Le Maux S et al. β-Lactoglobulin-linoleate complexes: In vitro digestion and the role of protein in fatty acid uptake. 2013 J. Dairy Sci. pmid:23684041
Saín J et al. Effects of trans-fatty acids on liver lipid metabolism in mice fed on diets showing different fatty acid composition. 2013 Ann. Nutr. Metab. pmid:23594856
Nørskov NP et al. Multicompartmental nontargeted LC-MS metabolomics: explorative study on the metabolic responses of rye fiber versus refined wheat fiber intake in plasma and urine of hypercholesterolemic pigs. 2013 J. Proteome Res. pmid:23596967
Jung CH et al. The preventive effect of uncarboxylated osteocalcin against free fatty acid-induced endothelial apoptosis through the activation of phosphatidylinositol 3-kinase/Akt signaling pathway. 2013 Metab. Clin. Exp. pmid:23639572
Cedernaes J et al. Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet. 2013 Lipids Health Dis pmid:23298201
Kälber T et al. Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. 2013 J. Dairy Res. pmid:23253429
Gillingham LG et al. Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. 2013 Am. J. Clin. Nutr. pmid:23221573
Carro M et al. Linoleic acid stimulates neutral lipid accumulation in lipid droplets of maturing bovine oocytes. 2013 Theriogenology pmid:23273433
Khan AA et al. Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. 2013 Nanomedicine (Lond) pmid:23311988
Graves JP et al. Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily. 2013 Drug Metab. Dispos. pmid:23315644
Carey AN et al. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. 2013 Nutr Neurosci pmid:23321679
Ramsden CE et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. 2013 BMJ pmid:23386268
Bin Q et al. The caspase pathway of linoelaidic acid (9t, 12t-c18:2)-induced apoptosis in human umbilical vein endothelial cells. 2013 Lipids pmid:23065354
Ghisolfi J et al. Nutrient intakes of children aged 1-2 years as a function of milk consumption, cows' milk or growing-up milk. 2013 Public Health Nutr pmid:23098567
Guo J et al. Selective transport of long-chain fatty acids by FAT/CD36 in skeletal muscle of broilers. 2013 Animal pmid:23031491
Kiernan M et al. The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. 2013 Reprod. Fertil. Dev. pmid:23036717
Franco-Pons N et al. Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis. 2013 Ann. Surg. pmid:22964727
Whelan J and Fritsche K Linoleic acid. 2013 Adv Nutr pmid:23674797
Men XM et al. Age-related changes and nutritional regulation of myosin heavy-chain composition in longissimus dorsi of commercial pigs. 2013 Animal pmid:23764195
Ndhlala AR et al. Anti-oxidative and cholinesterase inhibitory effects of leaf extracts and their isolated compounds from two closely related Croton species. 2013 Molecules pmid:23377133
Al-Bishri WM Favorable effects of flaxseed supplemented diet on liver and kidney functions in hypertensive Wistar rats. 2013 J Oleo Sci pmid:24005015
Han L et al. Hydroxyl radical induced by lipid in Maillard reaction model system promotes diet-derived N(ε)-carboxymethyllysine formation. 2013 Food Chem. Toxicol. pmid:23959106
Aboshi T et al. Biosynthesis of linoleic acid in Tyrophagus mites (Acarina: Acaridae). 2013 Insect Biochem. Mol. Biol. pmid:23973745
Luo C et al. Vegetable oil thermosets reinforced by tannin-lipid formulations. 2013 Acta Biomater pmid:22975626
Ramirez AM et al. A trichome-specific linoleate lipoxygenase expressed during pyrethrin biosynthesis in pyrethrum. 2013 Lipids pmid:23893337
Hashim A et al. Antioxidant and α -amylase inhibitory property of phyllanthus virgatus L.: an in vitro and molecular interaction study. 2013 Biomed Res Int pmid:23957001
Xia Q et al. Fatty acid profile, oxidative stability and toxicological safety of bayberry kernel oil. 2013 Food Chem. Toxicol. pmid:23867545
Le Maux S et al. Complexes between linoleate and native or aggregated β-lactoglobulin: interaction parameters and in vitro cytotoxic effect. 2013 Food Chem pmid:23870962
Aladedunye F and Przybylski R Frying stability of high oleic sunflower oils as affected by composition of tocopherol isomers and linoleic acid content. 2013 Food Chem pmid:23870970
Chen CS et al. Preference for linoleic acid in obesity-prone and obesity-resistant rats is attenuated by the reduction of CD36 on the tongue. 2013 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24154509
Reinders I et al. Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. 2013 Eur J Clin Nutr pmid:24084512
Navarro-Guillén C et al. Interaction between dietary levels of LC-PUFA and vegetable oil sources in Senegalese sole (Solea senegalensis) post-larvae: puzzling results suggesting complete biosynthesis pathway from C18 PUFA to DHA. 2013 Commun. Agric. Appl. Biol. Sci. pmid:25141696
Li P et al. Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. 2013 Cell. Physiol. Biochem. pmid:24335176
Sato K et al. Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on U46619-induced contraction in rat aorta. 2013 J Smooth Muscle Res pmid:24304639
De Weirdt R et al. A simulated mucus layer protects Lactobacillus reuteri from the inhibitory effects of linoleic acid. 2013 Benef Microbes pmid:24311313
Okada Y et al. Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization. 2013 Clin. Exp. Immunol. pmid:24028683
Yamagishi K et al. Plasma fatty acid composition and incident ischemic stroke in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. 2013 Cerebrovasc. Dis. pmid:23920478