Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chamberlain J et al. | Fatty acid profiles of major food sources of howler monkeys (Alouatta palliata) in the neotropics. | 1993 | Experientia | pmid:8104821 |
Spady DK | Regulatory effects of individual n-6 and n-3 polyunsaturated fatty acids on LDL transport in the rat. | 1993 | J. Lipid Res. | pmid:8105015 |
DeWille JW and Farmer SJ | Linoleic acid controls neonatal tissue-specific stearoyl-CoA desaturase mRNA levels. | 1993 | Biochim. Biophys. Acta | pmid:8105893 |
Hamberg M et al. | Sequential oxygenation of linoleic acid in the fungus Gaeumannomyces graminis: stereochemistry of dioxygenase and hydroperoxide isomerase reactions. | 1994 | Arch. Biochem. Biophys. | pmid:8117115 |
Loidl-Stahlhofen A and Spiteller G | alpha-Hydroxyaldehydes, products of lipid peroxidation. | 1994 | Biochim. Biophys. Acta | pmid:8117742 |
Kochetova MM et al. | [The antiatherogenic action of plant oils with added omega-3 polyunsaturated fatty acids]. | 1993 | Biull Eksp Biol Med | pmid:8117967 |
Hernández-Muñoz I et al. | Toxic oil stimulates collagen synthesis acting at a pretranslational level in cultured fat-storing cells. | 1994 | Gastroenterology | pmid:8119541 |
Schürer NY et al. | Evidence for a novel keratinocyte fatty acid uptake mechanism with preference for linoleic acid: comparison of oleic and linoleic acid uptake by cultured human keratinocytes, fibroblasts and a human hepatoma cell line. | 1994 | Biochim. Biophys. Acta | pmid:8123682 |
Liu XH and Rose DP | Stimulation of type IV collagenase expression by linoleic acid in a metastatic human breast cancer cell line. | 1994 | Cancer Lett. | pmid:8124668 |
Rao SI et al. | The lipoxygenase activity of myoglobin. Oxidation of linoleic acid by the ferryl oxygen rather than protein radical. | 1994 | J. Biol. Chem. | pmid:8125933 |
Castell JV et al. | Photodynamic lipid peroxidation by the photosensitizing nonsteroidal antiinflammatory drugs suprofen and tiaprofenic acid. | 1994 | Photochem. Photobiol. | pmid:8127938 |
Chopra M et al. | Free radical scavenging of lutein in vitro. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8129303 |
Ip C et al. | Potential of food modification in cancer prevention. | 1994 | Cancer Res. | pmid:8137319 |
Carlotti ME et al. | Inhibition of lipoperoxidation of linoleic acid by five antioxidants of different lipophilicity. | 1994 | Pharmazie | pmid:8140131 |
Calder PC et al. | Triacylglycerol metabolism by lymphocytes and the effect of triacylglycerols on lymphocyte proliferation. | 1994 | Biochem. J. | pmid:8141773 |
Shiina T et al. | Eicosapentaenoic acid and docosahexaenoic acid suppress the proliferation of vascular smooth muscle cells. | 1993 | Atherosclerosis | pmid:8141854 |
Paiement J et al. | Modulation of GTP-dependent fusion by linoleic and arachidonic acid in derivatives of rough endoplasmic reticulum from rat liver. | 1994 | Biochim. Biophys. Acta | pmid:8142417 |
Jenkins TC et al. | Dietary soybean oil changes lipolytic rate and composition of fatty acids in plasma membranes of ovine adipocytes. | 1994 | J. Nutr. | pmid:8145079 |
Sakai K et al. | Fatty acid compositions of plasma lipids in atopic dermatitis/asthma patients. | 1994 | Arerugi | pmid:8147707 |
Reaven PD et al. | Effects of linoleate-enriched and oleate-enriched diets in combination with alpha-tocopherol on the susceptibility of LDL and LDL subfractions to oxidative modification in humans. | 1994 | Arterioscler. Thromb. | pmid:8148354 |
Kanekal S and Kehrer JP | Metabolism of cyclophosphamide by lipoxygenases. | 1994 Jan-Feb | Drug Metab. Dispos. | pmid:8149893 |
Araki K et al. | Reduced cytotoxicity of a root canal sealer through eugenol substitution. | 1993 | J Endod | pmid:8151243 |
Fingerote RJ et al. | Gradient for D-glucose and linoleic acid uptake along the crypt-villus axis of rabbit jejunal brush border membrane vesicles. | 1994 | Lipids | pmid:8152345 |
Mabayo RT et al. | Interactions between medium-chain and long-chain triacylglycerols in lipid and energy metabolism in growing chicks. | 1994 | Lipids | pmid:8152347 |
Hirayama O et al. | Singlet oxygen quenching ability of naturally occurring carotenoids. | 1994 | Lipids | pmid:8152349 |
Sabolovic D et al. | Alterations of uninfected red blood cells in malaria. | 1994 | Parasitol. Res. | pmid:8153129 |
Nelson MJ et al. | Structural characterization of alkyl and peroxyl radicals in solutions of purple lipoxygenase. | 1994 | Biochemistry | pmid:8161558 |
Fuchs GJ et al. | Effect of dietary fat on cardiovascular risk factors in infancy. | 1994 | Pediatrics | pmid:8165074 |
Cho Y and Ziboh VA | Incorporation of 13-hydroxyoctadecadienoic acid (13-HODE) into epidermal ceramides and phospholipids: phospholipase C-catalyzed release of novel 13-HODE-containing diacylglycerol. | 1994 | J. Lipid Res. | pmid:8169529 |
Mann NJ et al. | The effect of linoleic, arachidonic and eicosapentaenoic acid supplementation on prostacyclin production in rats. | 1994 | Lipids | pmid:8170284 |
Appel MJ et al. | Effects of dietary linoleic acid on pancreatic carcinogenesis in rats and hamsters. | 1994 | Cancer Res. | pmid:8174115 |
Schilstra MJ et al. | Effect of nonionic detergents on lipoxygenase catalysis. | 1994 | Lipids | pmid:8177015 |
Avellini L et al. | Linoleic acid passage through the blood-brain barrier and a possible effect of age. | 1994 | Neurochem. Res. | pmid:8183422 |
Jakobsen K et al. | Heat production and quantitative oxidation of nutrients by physical activity in pigs. | 1994 | Ann. Nutr. Metab. | pmid:8185282 |
Belluzzi A et al. | Short report: zinc sulphate supplementation corrects abnormal erythrocyte membrane long-chain fatty acid composition in patients with Crohn's disease. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186338 |
Cronan JE and Rock CO | The presence of linoleic acid in Escherichia coli cannot be confirmed. | 1994 | J. Bacteriol. | pmid:8188608 |
Hodgson JM et al. | Can linoleic acid contribute to coronary artery disease? | 1993 | Am. J. Clin. Nutr. | pmid:8192728 |
Truswell AS | Can linoleic acid contribute to coronary artery disease? | 1994 | Am. J. Clin. Nutr. | pmid:8198070 |
Andrassy RJ et al. | Linoleic acid enhances mitogen response and survival of septic weanling rats. | 1994 | J. Pediatr. Surg. | pmid:8201499 |
Yamashiro Y et al. | Effects of ursodeoxycholic acid treatment on essential fatty acid deficiency in patients with biliary atresia. | 1994 | J. Pediatr. Surg. | pmid:8201513 |
Glasgow WC and Eling TE | Structure-activity relationship for potentiation of EGF-dependent mitogenesis by oxygenated metabolites of linoleic acid. | 1994 | Arch. Biochem. Biophys. | pmid:8203891 |
Grammatopoulos D et al. | The human myometrial CRH receptor: G proteins and second messengers. | 1994 | Mol. Cell. Endocrinol. | pmid:8206332 |
Sakuma S et al. | Effect of 13-hydroperoxyoctadecadienoic acid on 15-hydroxy prostaglandin dehydrogenase activity in rabbit kidney cortex. | 1993 | Prostaglandins | pmid:8210445 |
Viscardi RM and Max SR | Unsaturated fatty acid modulation of glucocorticoid receptor binding in L2 cells. | 1993 | Steroids | pmid:8212085 |
de Deckere EA et al. | Hepatic de novo fatty acid synthesis in the rat. | 1993 | Ann. Nutr. Metab. | pmid:8215236 |
Jakobsen K et al. | The biological activity of natural source tocopherols in chickens fed fresh or oxidized fat rich in linoleic acid. | 1993 | Arch Tierernahr | pmid:8215903 |
Spiteller G | Review: on the chemistry of oxidative stress. | 1993 | J Lipid Mediat | pmid:8219002 |
Daret D et al. | Synthesis of monohydroxylated fatty acids from linoleic acid by rat aortic smooth muscle cells and tissues: influence on prostacyclin production. | 1993 | J. Lipid Res. | pmid:8228632 |
Chan JK et al. | Effect of dietary alpha-linolenic acid and its ratio to linoleic acid on platelet and plasma fatty acids and thrombogenesis. | 1993 | Lipids | pmid:8231657 |
Markovic DZ and Patterson LK | Benzophenone-sensitized lipid peroxidation in linoleate micelles. | 1993 | Photochem. Photobiol. | pmid:8234464 |