Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Whigham LD et al. | Conjugated linoleic acid: implications for human health. | 2000 | Pharmacol. Res. | pmid:11058400 |
Steinkamp G et al. | Energy supplements rich in linoleic acid improve body weight and essential fatty acid status of cystic fibrosis patients. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:11045840 |
Soriano CR et al. | Cutaneous application of vegetable oil as a coadjutant in the nutritional management of preterm infants. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:11045835 |
Moran JH et al. | Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. | 2000 | Toxicol. Appl. Pharmacol. | pmid:11042099 |
French SJ et al. | The effects of intestinal infusion of long-chain fatty acids on food intake in humans. | 2000 | Gastroenterology | pmid:11040181 |
Smith HL et al. | Development of a serum-free system for the in vitro cultivation of Brugia malayi infective-stage larvae. | 2000 | Exp. Parasitol. | pmid:11038308 |
Meaney CM and O'Driscoll CM | A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model. | 2000 | Int J Pharm | pmid:11036226 |
Van de Velde M et al. | Effects of lipids on the functional and metabolic recovery from global myocardial stunning in isolated rabbit hearts. | 2000 | Cardiovasc. Res. | pmid:11033115 |
Qian SY et al. | EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. | 2000 | Free Radic. Biol. Med. | pmid:11025200 |
Kelavkar UP et al. | Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging. | 2000 | Carcinogenesis | pmid:11023533 |
West DB et al. | Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression. | 2000 | J. Nutr. | pmid:11015475 |
Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
Lucchi L et al. | Changes in conjugated linoleic acid and its metabolites in patients with chronic renal failure. | 2000 | Kidney Int. | pmid:11012903 |
DeLany JP et al. | Differential oxidation of individual dietary fatty acids in humans. | 2000 | Am. J. Clin. Nutr. | pmid:11010930 |
Sol Morales M et al. | Milk fat composition of Holstein and Jersey cows with control or depleted copper status and fed whole soybeans or tallow. | 2000 | J. Dairy Sci. | pmid:11003245 |
Morales MS et al. | Effects of fat source and copper on unsaturation of blood and milk triacylglycerol fatty acids in Holstein and Jersey cows. | 2000 | J. Dairy Sci. | pmid:11003244 |
Jones DF et al. | Short communication: influence of dietary tallow and fish oil on milk fat composition. | 2000 | J. Dairy Sci. | pmid:11003234 |
Schaffrath U et al. | Characterization of RCI-1, a chloroplastic rice lipoxygenase whose synthesis is induced by chemical plant resistance activators. | 2000 | Eur. J. Biochem. | pmid:10998053 |
Han KH et al. | Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. | 2000 | J. Clin. Invest. | pmid:10995790 |
Livisay SA et al. | Impact of dietary conjugated linoleic acid on the oxidative stability of rat liver microsomes and skeletal muscle homogenates. | 2000 | J. Agric. Food Chem. | pmid:10995331 |
Antony SM et al. | Antioxidative effect of maillard reaction products formed from honey at different reaction times. | 2000 | J. Agric. Food Chem. | pmid:10995301 |
Kim SJ et al. | Improvement of oxidative stability of conjugated linoleic acid (CLA) by microencapsulation in cyclodextrins. | 2000 | J. Agric. Food Chem. | pmid:10995292 |
Horrobin DF | Commentary on the workshop statement: are we really sure that arachidonic acid and linoleic acid are bad things? | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991771 |
Cunnane SC | Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991770 |
Crawford MA | Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991768 |
Galli C | Commentary on the workshop statement. Essentiality of and recommended dietary intake of Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991767 |
Simopoulos AP | Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991765 |
Meinelt T et al. | Correlation of diets high in n-6 polyunsaturated fatty acids with high growth rate in zebrafish (Danio rerio). | 2000 | Comp. Med. | pmid:10987667 |
Hover CG and Kulkarni AP | Human term placental lipoxygenase-mediated N-demethylation of phenothiazines and insecticides in the presence of linoleic acid. | 2000 | Placenta | pmid:10985967 |
O'Quinn PR et al. | Effects of modified tall oil versus a commercial source of conjugated linoleic acid and increasing levels of modified tall oil on growth performance and carcass characteristics of growing-finishing pigs. | 2000 | J. Anim. Sci. | pmid:10985411 |
Oak J et al. | Synthetically prepared Aamadori-glycated phosphatidylethanolaminecan trigger lipid peroxidation via free radical reactions. | 2000 | FEBS Lett. | pmid:10984609 |
Evans M et al. | Conjugated linoleic acid suppresses triglyceride accumulation and induces apoptosis in 3T3-L1 preadipocytes. | 2000 | Lipids | pmid:10984113 |
Kim JG et al. | Reduction of aflatoxins by Korean soybean paste and its effect on cytotoxicity and reproductive toxicity--part 1. Inhibition of growth and aflatoxin production of Aspergillus parasiticus by Korean soybean paste (Doen-jang) and identification of the active component. | 2000 | J. Food Prot. | pmid:10983810 |
Kajita M et al. | Enhanced enteral bioavailability of vancomycin using water-in-oil-in-water multiple emulsion incorporating highly purified unsaturated fatty acid. | 2000 | J Pharm Sci | pmid:10980499 |
Messa P et al. | Abnormal arachidonic acid content of red blood cell membranes and main lithogenic factors in stone formers. | 2000 | Nephrol. Dial. Transplant. | pmid:10978396 |
Monteggia E et al. | Phospholipid distribution in murine mammary adenocarcinomas induced by activated neu oncogene. | 2000 | Cancer Detect. Prev. | pmid:10975281 |
Moosmann B and Behl C | Cytoprotective antioxidant function of tyrosine and tryptophan residues in transmembrane proteins. | 2000 | Eur. J. Biochem. | pmid:10971578 |
Higdon JV et al. | Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F(2)-isoprostanes. | 2000 | Am. J. Clin. Nutr. | pmid:10966889 |
DeLany JP and West DB | Changes in body composition with conjugated linoleic acid. | 2000 | J Am Coll Nutr | pmid:10963469 |
Watkins BA and Seifert MF | Conjugated linoleic acid and bone biology. | 2000 | J Am Coll Nutr | pmid:10963468 |
Kritchevsky D et al. | Influence of conjugated linoleic acid (CLA) on establishment and progression of atherosclerosis in rabbits. | 2000 | J Am Coll Nutr | pmid:10963467 |
Griinari JM et al. | Conjugated linoleic acid is synthesized endogenously in lactating dairy cows by Delta(9)-desaturase. | 2000 | J. Nutr. | pmid:10958825 |
Yang L et al. | Oxidative stability of conjugated linoleic acid isomers. | 2000 | J. Agric. Food Chem. | pmid:10956070 |
Saxena NC | Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits. | 2000 | Pflugers Arch. | pmid:10954324 |
Hennig B et al. | Fatty acid-mediated activation of vascular endothelial cells. | 2000 | Metab. Clin. Exp. | pmid:10954018 |
Kritchevsky D | Antimutagenic and some other effects of conjugated linoleic acid. | 2000 | Br. J. Nutr. | pmid:10953669 |
Tůmová L and Dusek J | [Effect of linoleic acid on the production of secondary metabolites]. | 2000 | Ceska Slov Farm | pmid:10953448 |
Cohen LA et al. | The influence of different varieties of olive oil on N-methylnitrosourea(NMU)-induced mammary tumorigenesis. | 2000 Jul-Aug | Anticancer Res. | pmid:10953289 |
Jeppesen PB et al. | Deficiencies of essential fatty acids, vitamin A and E and changes in plasma lipoproteins in patients with reduced fat absorption or intestinal failure. | 2000 | Eur J Clin Nutr | pmid:10951512 |
Sijben JW et al. | Dietary linoleic acid divergently affects immune responsiveness of growing layer hens. | 2000 | Poult. Sci. | pmid:10947178 |