Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Cholestasis D002779 23 associated lipids
Olfaction Disorders D000857 17 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Glomerulonephritis D005921 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Psoriasis D011565 47 associated lipids
Brain Edema D001929 20 associated lipids
Alcoholism D000437 27 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Starvation D013217 47 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Brain Ischemia D002545 89 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Decsi T et al. Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:10817286
Lapillonne A et al. Effects of liver transplantation on long-chain polyunsaturated fatty acid status in infants with biliary atresia. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:10817283
Blask DE et al. New insights into melatonin regulation of cancer growth. 1999 Adv. Exp. Med. Biol. pmid:10810531
Wang J and Zhang Y [Effect of the long chain polyunsaturated fatty acids levels in mothers on fetuses]. 1998 Zhonghua Fu Chan Ke Za Zhi pmid:10806659
Kachhap SK et al. Effect of omega-6 polyunsaturated fatty acid (linoleic acid) on BRCA1 gene expression in MCF-7 cell line. 2000 Cancer Lett. pmid:10806298
Iwase H et al. Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase. 2000 Free Radic. Biol. Med. pmid:10802222
Gupta SV and Khosla P Pork fat and chicken fat similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. 2000 J. Nutr. pmid:10801922
Itokazu N et al. Bidirectional actions of docosahexaenoic acid on hippocampal neurotransmissions in vivo. 2000 Brain Res. pmid:10799687
Canudas N et al. Photobiological properties of nabumetone (4-[6-methoxy-2-naphthalenyl]-2-butanone), a novel non-steroidal anti-inflammatory and analgesic agent. 2000 Pharmazie pmid:10798241
Kaya A Properties and stability of butter oil obtained from milk and yoghurt. 2000 Nahrung pmid:10795582
Mandin O et al. Volatile compounds from potato-like model systems. 1999 J. Agric. Food Chem. pmid:10794636
McEvoy TG et al. Fatty acid composition of lipids in immature cattle, pig and sheep oocytes with intact zona pellucida. 2000 J. Reprod. Fertil. pmid:10793638
Kharchenko OV et al. [Kinetic mechanisms of linoleic acid oxidation by 5-lipoxygenase from Solanum tuberosum L]. 1999 Jul-Aug Ukr Biokhim Zh (1999) pmid:10791055
McCarty MF Toward a wholly nutritional therapy for type 2 diabetes. 2000 Med. Hypotheses pmid:10783493
Charnock JS Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780878
Hover CG and Kulkarni AP A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780874
Talcott ST et al. Antioxidant changes and sensory properties of carrot puree processed with and without periderm tissue. 2000 J. Agric. Food Chem. pmid:10775391
Liégeois C et al. Measuring antioxidant efficiency of wort, malt, and hops against the 2,2'-azobis(2-amidinopropane) dihydrochloride-induced oxidation of an aqueous dispersion of linoleic acid. 2000 J. Agric. Food Chem. pmid:10775361
Sasaki T et al. Dietary docosahexaenoic acid can alter the surface expression of CD4 and CD8 on T cells in peripheral blood. 2000 J. Agric. Food Chem. pmid:10775347
Siefken W et al. Regulation of cholesterol synthesis by oleic and palmitic acid in keratinocytes. 2000 Exp. Dermatol. pmid:10772388
Kritharides L Ascorbic acid and copper in linoleate oxidation--Dunkley revisited. 1999 Redox Rep. pmid:10772064
Mogul R et al. Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase. 2000 Biochemistry pmid:10769137
Littman ED et al. Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion. 2000 Pancreas pmid:10766451
Yehuda S et al. Fatty acid mixture counters stress changes in cortisol, cholesterol, and impair learning. 2000 Int. J. Neurosci. pmid:10765992
Mohan IK and Das UN Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765977
Punchard NA et al. Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765976
Tomsits E et al. Effects of early nutrition on free radical formation in VLBW infants with respiratory distress. 2000 J Am Coll Nutr pmid:10763905
MacDonald HB Conjugated linoleic acid and disease prevention: a review of current knowledge. 2000 J Am Coll Nutr pmid:10759137
Hubbard NE et al. Reduction of murine mammary tumor metastasis by conjugated linoleic acid. 2000 Cancer Lett. pmid:10755392
Trimborn M et al. Linoleic acid cytotoxicity to bovine lens epithelial cells: influence of albumin on linoleic acid uptake and cytotoxicity. 2000 Mar-Jun Ophthalmic Res. pmid:10754440
Rubbo H et al. Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. 2000 J. Biol. Chem. pmid:10753874
Garcia HS et al. Interesterification (acidolysis) of butterfat with conjugated linoleic acid in a batch reactor. 2000 J. Dairy Sci. pmid:10750090
Whalen MM et al. Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. 1999 Cell. Physiol. Biochem. pmid:10749996
Larqué E et al. Dietary trans fatty acids affect the essential fatty-acid concentration of rat milk. 2000 J. Nutr. pmid:10736340
Hudson JA et al. Identification and enumeration of oleic acid and linoleic acid hydrating bacteria in the rumen of sheep and cows. 2000 J. Appl. Microbiol. pmid:10735997
Clemmesen JO et al. Plasma phospholipid fatty acid pattern in severe liver disease. 2000 J. Hepatol. pmid:10735619
Hochi S et al. Effect of linoleic acid-albumin in the culture medium on freezing sensitivity of in vitro-produced bovine morulae. 1999 Theriogenology pmid:10734383
Kemp B et al. Influence of linoleic/linolenic acid ratio in the diet of periparturient cattle on plasma concentrations of PGF2 alpha metabolite and placental expulsion rate. 1998 Theriogenology pmid:10732036
Draper AJ and Hammock BD Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. 2000 Arch. Biochem. Biophys. pmid:10729206
Adam O Linoleic acid - the fall of an angel? 1999 Ann. Nutr. Metab. pmid:10725772
Fidler N et al. Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women. 1999 Ann. Nutr. Metab. pmid:10725767
Adeyeye EI et al. Fatty acid composition of six varieties of dehulled African yam bean (Sphenostylis stenocarpa) flour. 1999 Int J Food Sci Nutr pmid:10719567
Baron CP et al. Peroxidation of linoleate at physiological pH: hemichrome formation by substrate binding protects against metmyoglobin activation by hydrogen peroxide. 2000 Free Radic. Biol. Med. pmid:10719236
Chavali SR and Forse RA Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10718106
Cox JE et al. Suppression of food intake, body weight, and body fat by jejunal fatty acid infusions. 2000 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:10712279
Takahashi N Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). 2000 Biol. Pharm. Bull. pmid:10706389
Kitts DD et al. Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. 1999 Mol. Cell. Biochem. pmid:10705999
Shimada A et al. Phytotoxicity of indole-3-acetic acid produced by the fungus, Pythium aphanidermatum. 2000 Biosci. Biotechnol. Biochem. pmid:10705467
Delmas-Beauvieux MC et al. Liposomes as fatty acids carriers in isolated rat liver: effect on energy metabolism and on isolated mitochondria activity. 2000 MAGMA pmid:10697225
Martin JC et al. Effects of conjugated linoleic acid isomers on lipid-metabolizing enzymes in male rats. 2000 Lipids pmid:10695929