Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fox SR et al. | The biosynthesis of oxylipins of linoleic and arachidonic acids by the sewage fungus Leptomitus lacteus, including the identification of 8R-Hydroxy-9Z,12Z-octadecadienoic acid. | 2000 | Lipids | pmid:10695920 |
Kim D and Pleumsamran A | Cytoplasmic unsaturated free fatty acids inhibit ATP-dependent gating of the G protein-gated K(+) channel. | 2000 | J. Gen. Physiol. | pmid:10694258 |
Sekiwa Y et al. | Isolation of novel glucosides related to gingerdiol from ginger and their antioxidative activities. | 2000 | J. Agric. Food Chem. | pmid:10691642 |
López-Nicolás JM et al. | Effect of calcium on the oxidation of linoleic acid by potato (Solanum tuberosum var. Desiree) tuber 5-lipoxygenase. | 2000 | J. Agric. Food Chem. | pmid:10691630 |
Saito A et al. | Effects of capsaicin on biliary free fatty acids in rats. | 2000 | Int J Vitam Nutr Res | pmid:10683757 |
Sébédio JL et al. | Recent advances in conjugated linoleic acid research. | 1999 | Curr Opin Clin Nutr Metab Care | pmid:10678680 |
Rüttinger HH and Radschuweit A | Determination of peroxides by capillary zone electrophoresis with amperometric detection. | 2000 | J Chromatogr A | pmid:10677087 |
Jarmuszkiewicz W et al. | First evidence and characterization of an uncoupling protein in fungi kingdom: CpUCP of Candida parapsilosis. | 2000 | FEBS Lett. | pmid:10675527 |
Larqué E et al. | Dietary trans fatty acids affect docosahexaenoic acid concentrations in plasma and liver but not brain of pregnant and fetal rats. | 2000 | Pediatr. Res. | pmid:10674359 |
Halle I | [The effect of palm oil and safflower oil in the feed of parent fattening hens on fertility, hatchability and growth of progeny]. | 1999 | Arch Tierernahr | pmid:10674173 |
Grobas S et al. | Influence of dietary energy, supplemental fat and linoleic acid concentration on performance of laying hens at two ages. | 1999 | Br. Poult. Sci. | pmid:10670682 |
Jira W and Spiteller G | Dramatic increase of linoleic acid peroxidation products by aging, atherosclerosis, and rheumatoid arthritis. | 1999 | Adv. Exp. Med. Biol. | pmid:10667371 |
Greene JF and Hammock BD | Toxicity of linoleic acid metabolites. | 1999 | Adv. Exp. Med. Biol. | pmid:10667370 |
Buchanan MR | Linoleic acid metabolites in health and disease. | 1999 | Adv. Exp. Med. Biol. | pmid:10667369 |
Brash AR et al. | Investigation of a second 15S-lipoxygenase in humans and its expression in epithelial tissues. | 1999 | Adv. Exp. Med. Biol. | pmid:10667314 |
Heeley EL et al. | Phospholipid molecular species of bronchoalveolar lavage fluid after local allergen challenge in asthma. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10666114 |
Rukkwamsuk T et al. | Interrelation of fatty acid composition in adipose tissue, serum, and liver of dairy cows during the development of fatty liver postpartum. | 2000 | J. Dairy Sci. | pmid:10659963 |
Romero P et al. | Short communication: concentration of conjugated linoleic acid from milk fat with a continuous supercritical fluid processing system. | 2000 | J. Dairy Sci. | pmid:10659958 |
Berghaus TM et al. | Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation. | 2000 | Biol. Neonate | pmid:10657686 |
de Deckere EA et al. | Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. | 1999 | Br. J. Nutr. | pmid:10655980 |
Oriani G et al. | Effects of intramuscular injection of alpha-tocopheryl acetate on fatty acid profile in lamb liver. | 1999 | Int J Vitam Nutr Res | pmid:10642895 |
Salo P et al. | Low-saturated fat, low-cholesterol diet in 3-year-old children: effect on intake and composition of trans fatty acids and other fatty acids in serum phospholipid fraction-The STRIP study. Special Turku coronary Risk factor Intervention Project for children. | 2000 | J. Pediatr. | pmid:10636973 |
Hayat L et al. | Fatty acid composition of human milk in Kuwaiti mothers. | 1999 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:10631803 |
Pariza MW et al. | Conjugated linoleic acid and the control of cancer and obesity. | 1999 | Toxicol. Sci. | pmid:10630598 |
Nair J | Lipid peroxidation-induced etheno-DNA adducts in humans. | 1999 | IARC Sci. Publ. | pmid:10626208 |
Chung FL et al. | Role of 1,N2-propanodeoxyguanosine adducts as endogenous DNA lesions in rodents and humans. | 1999 | IARC Sci. Publ. | pmid:10626207 |
Connolly JM et al. | Effects of reduced dietary linoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice. | 1999 | Nutr Cancer | pmid:10624705 |
Horrobin DF | Essential fatty acid metabolism and its modification in atopic eczema. | 2000 | Am. J. Clin. Nutr. | pmid:10617999 |
Ziboh VA et al. | Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. | 2000 | Am. J. Clin. Nutr. | pmid:10617998 |
Dutta-Roy AK | Transport mechanisms for long-chain polyunsaturated fatty acids in the human placenta. | 2000 | Am. J. Clin. Nutr. | pmid:10617989 |
Crawford M | Placental delivery of arachidonic and docosahexaenoic acids: implications for the lipid nutrition of preterm infants. | 2000 | Am. J. Clin. Nutr. | pmid:10617983 |
Gibson RA and Makrides M | n-3 polyunsaturated fatty acid requirements of term infants. | 2000 | Am. J. Clin. Nutr. | pmid:10617980 |
Uauy R and Hoffman DR | Essential fat requirements of preterm infants. | 2000 | Am. J. Clin. Nutr. | pmid:10617979 |
Sanders TA | Polyunsaturated fatty acids in the food chain in Europe. | 2000 | Am. J. Clin. Nutr. | pmid:10617968 |
Meerarani P et al. | Zinc protects against apoptosis of endothelial cells induced by linoleic acid and tumor necrosis factor alpha. | 2000 | Am. J. Clin. Nutr. | pmid:10617950 |
Ghebremeskel K et al. | Maternal diet high in fat reduces docosahexaenoic acid in liver lipids of newborn and sucking rat pups. | 1999 | Br. J. Nutr. | pmid:10615212 |
Jie MS and Cheung SW | Fullerene lipids: synthesis of C60 fullerene derivatives bearing a long-chain saturated or unsaturated triester system. | 1999 | Lipids | pmid:10606046 |
Speake BK et al. | Lipid composition of eggs of an oviparous lizard (Bassiana duperreyi). | 1999 | Lipids | pmid:10606044 |
Peres CM et al. | Thioglycolate-elicited rat macrophages exhibit alterations in incorporation and oxidation of fatty acids. | 1999 | Lipids | pmid:10606042 |
Hamberg M | An epoxy alcohol synthase pathway in higher plants: biosynthesis of antifungal trihydroxy oxylipins in leaves of potato. | 1999 | Lipids | pmid:10606035 |
Matsusue K et al. | A highly toxic coplanar polychlorinated biphenyl compound suppresses Delta5 and Delta6 desaturase activities which play key roles in arachidonic acid synthesis in rat liver. | 1999 | Chem. Res. Toxicol. | pmid:10604864 |
Klein J et al. | Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. | 1999 | Ther Drug Monit | pmid:10604826 |
Sprinz H et al. | Mechanism of thiyl radical-catalyzed isomerization of unsaturated fatty acid residues in homogeneous solution and in liposomes. | 2000 | Biochim. Biophys. Acta | pmid:10601698 |
Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
Velēna A et al. | Derivatives of 1,4-dihydropyridines as modulators of ascorbate-induced lipid peroxidation and high-amplitude swelling of mitochondria, caused by ascorbate, sodium linoleate and sodium pyrophosphate. | 1999 | Cell Biochem. Funct. | pmid:10587611 |
Dionisi F et al. | Stability of cyclopropane and conjugated linoleic acids during fatty acid quantification in lactic acid bacteria. | 1999 | Lipids | pmid:10580338 |
Yin JJ et al. | Effects of conjugated linoleic acid on oxygen diffusion-concentration product and depletion in membranes by using electron spin resonance spin-label oximetry. | 1999 | Lipids | pmid:10580328 |
Fukuda N et al. | Effect of dietary sesamin on metabolic fate of an exogenous linolelaidic acid in perfused rat liver. | 1999 | J. Nutr. Sci. Vitaminol. | pmid:10575634 |
Hsu AF et al. | Immobilized lipoxygenase in a packed-bed column bioreactor: continuous oxygenation of linoleic acid. | 1999 | Biotechnol. Appl. Biochem. | pmid:10574694 |
Sakono M et al. | Dietary conjugated linoleic acid reciprocally modifies ketogenesis and lipid secretion by the rat liver. | 1999 | Lipids | pmid:10574665 |