Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cantrill RC et al. | Variations in temperature and oxygen content do not alter levels of thiobarbiturate reactive material in human breast tumour cells (ZR-75-1) incubated with gamma-linolenic acid. | 1993 Sep-Oct | Anticancer Res. | pmid:8239521 |
| Biagi PL et al. | Erythrocyte membrane fatty acid composition in children with atopic dermatitis compared to age-matched controls. | 1993 | Acta Paediatr. | pmid:8241678 |
| Tanner JT et al. | Analysis of milk-based infant formula. Phase IV. Iodide, linoleic acid, and vitamins D and K: U.S. Food and Drug Administration-Infant Formula Council: collaborative study. | 1993 Sep-Oct | J AOAC Int | pmid:8241809 |
| Darmani H et al. | Interferon-gamma-stimulated uptake and turnover of linoleate and arachidonate in macrophages: a possible pathway for hypersensitivity to endotoxin. | 1993 | Cell. Immunol. | pmid:8242772 |
| Vargas F et al. | Photodegradation and in vitro phototoxicity of fenofibrate, a photosensitizing anti-hyperlipoproteinemic drug. | 1993 | Photochem. Photobiol. | pmid:8248320 |
| Jones AL et al. | Rapid induction of microsomal delta 12(omega 6)-desaturase activity in chilled Acanthamoeba castellanii. | 1993 | Biochem. J. | pmid:8250841 |
| Viola G et al. | Absorption and distribution of arachidonate in rats receiving lysophospholipids by oral route. | 1993 | J. Lipid Res. | pmid:8263409 |
| Whelan J et al. | Dietary arachidonate enhances tissue arachidonate levels and eicosanoid production in Syrian hamsters. | 1993 | J. Nutr. | pmid:8263613 |
| Blee E et al. | Regio- and stereoselectivity of cytochrome P-450 and peroxygenase-dependent formation of cis-12,13-epoxy-9(Z)-octadecenoic acid (vernolic acid) in Euphorbia lagascae. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8267615 |
| Sullivan JL et al. | Performance of dairy cows fed short staple, Pima, and cracked Pima cottonseed and feed characteristics. | 1993 | J. Dairy Sci. | pmid:8270698 |
| Dehaut F et al. | n-6 polyunsaturated fatty acids increase the neurite length of PC12 cells and embryonic chick motoneurons. | 1993 | Neurosci. Lett. | pmid:8272254 |
| Ettinger WH et al. | Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells. | 1994 | Arterioscler. Thromb. | pmid:8274481 |
| Oulhaj H et al. | Synthesis and distribution of rat Sertoli cell proteoglycans are modulated by linoleate and vitamin E. | 1993 | Biochem. Mol. Biol. Int. | pmid:8275018 |
| Lamb RG et al. | An in vitro model of ethanol-dependent liver cell injury. | 1994 | Hepatology | pmid:8276354 |
| Bronstein JC and Bull AW | The correlation between 13-hydroxyoctadecadienoate dehydrogenase (13-HODE dehydrogenase) and intestinal cell differentiation. | 1993 | Prostaglandins | pmid:8278616 |
| Murray MJ et al. | Effects of endotoxin on pigs prefed omega-3 vs. omega-6 fatty acid-enriched diets. | 1993 | Am. J. Physiol. | pmid:8279548 |
| Hrboticky N et al. | Lovastatin increases arachidonic acid levels and stimulates thromboxane synthesis in human liver and monocytic cell lines. | 1994 | J. Clin. Invest. | pmid:8282787 |
| Saito M and Yamaguchi M | Response of liver microsomal mixed-function oxidases to dietary linoleic acid levels in rats. | 1993 | J. Nutr. Sci. Vitaminol. | pmid:8283320 |
| Judd JT and Clevidence BA | Trans fatty acids in human nutrition. | 1993 | Acta Cardiol | pmid:8284978 |
| Grech ED et al. | Differential free-radical activity after successful and unsuccessful thrombolytic reperfusion in acute myocardial infarction. | 1993 | Coron. Artery Dis. | pmid:8287210 |
| Sunzeri FJ and Buehring GC | Lipids alter the level and distribution of mouse mammary tumor virus gp52 in vitro. | 1993 | Cancer Lett. | pmid:8287372 |
| Sanjurjo P et al. | Cross-sectional study of percentual changes in total plasmatic fatty acids during pregnancy. | 1993 | Horm. Metab. Res. | pmid:8288163 |
| Li Y et al. | Chemical and alpha-chymotrypsin-mediated proteolytic degradation of insulin in bile salt-unsaturated fatty acid mixed micellar systems. | 1993 | Pharm. Res. | pmid:8290478 |
| Ramasamy S et al. | Proteoglycans and endothelial barrier function: effect of linoleic acid exposure to porcine pulmonary artery endothelial cells. | 1993 | Atherosclerosis | pmid:8292102 |
| Marcelo CL and Dunham WR | Fatty acid metabolism studies of human epidermal cell cultures. | 1993 | J. Lipid Res. | pmid:8301228 |
| Yamaguchi Y et al. | Enhancement of aortic cholesterol deposition by dietary linoleic acid in cholesterol-fed mice: an animal model for primary screening of antiatherosclerotic agents. | 1993 | J Pharmacol Toxicol Methods | pmid:8305719 |
| Takatori T | [Relationship between postmortem change and biological reaction]. | 1993 | Nihon Hoigaku Zasshi | pmid:8309098 |
| Larner JM et al. | The isolation and characterization of estradiol-fatty acid esters in human ovarian follicular fluid. Identification of an endogenous long-lived and potent family of estrogens. | 1993 | J. Biol. Chem. | pmid:8314757 |
| Hernell O et al. | Does the bile salt-stimulated lipase of human milk have a role in the use of the milk long-chain polyunsaturated fatty acids? | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8315552 |
| Koba K et al. | Effects of dietary proteins on linoleic acid desaturation and membrane fluidity in rat liver microsomes. | 1993 | Lipids | pmid:8316055 |
| Vázquez CM et al. | Changes in fatty acid desaturation in hepatic and intestinal tissues induced by intestinal resection. | 1993 | Lipids | pmid:8316056 |
| Louw L and van der Westhuizen JP | Correlation between histopathology and linoleic acid levels in five meningioma types. | 1993 | Pathol. Res. Pract. | pmid:8321745 |
| Kaneko T et al. | Protective effect of lipophilic derivatives of ascorbic acid on lipid peroxide-induced endothelial injury. | 1993 | Arch. Biochem. Biophys. | pmid:8323284 |
| Wieland E et al. | Peroxidase-dependent metal-independent oxidation of low density lipoprotein in vitro: a model for in vivo oxidation? | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8327462 |
| Hansen HS | Linoleic acid as a precursor for acylation of transducin, a retinol G protein? | 1993 | Trends Biochem. Sci. | pmid:8328015 |
| Rich MR | Conformational analysis of arachidonic and related fatty acids using molecular dynamics simulations. | 1993 | Biochim. Biophys. Acta | pmid:8329458 |
| Hara I et al. | Role of calcium ion in Schistosoma mansoni cercarial tail loss induced by unsaturated fatty acids. | 1993 | J. Parasitol. | pmid:8331471 |
| Jacobsen BK et al. | Re: "Comparison of measures of fatty acid intake by subcutaneous fat aspirate, food frequency questionnaire, and diet records in a free-living population of US men". | 1993 | Am. J. Epidemiol. | pmid:8333420 |
| Dutta-Roy AK et al. | Purification and characterization of fatty acid-binding proteins from brown adipose tissue of the rat. | 1993 | Biochim. Biophys. Acta | pmid:8334153 |
| Kühn H et al. | Overexpression, purification and characterization of human recombinant 15-lipoxygenase. | 1993 | Biochim. Biophys. Acta | pmid:8334154 |
| Bioque G et al. | Metabolism of N-phenyllinoleamide by rat liver. | 1993 | J. Chromatogr. | pmid:8335697 |
| Guha SN et al. | Free radical reductive degradation of vic-dibromoalkanes and reaction of bromine atoms with polyunsaturated fatty acids: possible involvement of Br(.) in the 1,2-dibromoethane-induced lipid peroxidation. | 1993 | Arch. Biochem. Biophys. | pmid:8342946 |
| Roy R and Bélanger A | ZR-75-1 breast cancer cells generate nonconjugated steroids from low density lipoprotein-incorporated lipoidal dehydroepiandrosterone. | 1993 | Endocrinology | pmid:8344206 |
| Mao-Qiang M et al. | Inhibition of cholesterol and sphingolipid synthesis causes paradoxical effects on permeability barrier homeostasis. | 1993 | J. Invest. Dermatol. | pmid:8345219 |
| Roy SK et al. | Lipoxygenase activity in rat embryos and its potential for xenobiotic oxidation. | 1993 | Biol. Neonate | pmid:8353158 |
| Buchanan MR and Brister SJ | Altering vessel wall fatty acid metabolism: a new strategy for antithrombotic treatment. | 1993 | Semin. Thromb. Hemost. | pmid:8356461 |
| Zheng RL et al. | Inhibition of the autoxidation of linoleic acid by phenylpropanoid glycosides from Pedicularis in micelles. | 1993 | Chem. Phys. Lipids | pmid:8358852 |
| Chang WC et al. | Induction of arachidonate 12-lipoxygenase mRNA by epidermal growth factor in A431 cells. | 1993 | J. Biol. Chem. | pmid:8360167 |
| Davis PA et al. | A linoleate-enriched cheese product reduces low-density lipoprotein in moderately hypercholesterolemic adults. | 1993 | Ann. Intern. Med. | pmid:8363165 |
| Rabinowitch HD et al. | Escherichia coli produces linoleic acid during late stationary phase. | 1993 | J. Bacteriol. | pmid:8366020 |
| Hong CY et al. | Linoleate-rich triacylglycerol in Panax pseudo-ginseng improves erythrocyte deformability in vitro. | 1993 | Planta Med. | pmid:8372148 |
| Black JM and Kinsella JE | Dietary n-3 fatty acids alter murine peritoneal macrophage cytotoxicity. | 1993 | Ann. Nutr. Metab. | pmid:8373135 |
| van Zoeren-Grobben D et al. | Lipid peroxidation in human milk and infant formula: effect of storage, tube feeding and exposure to phototherapy. | 1993 | Acta Paediatr. | pmid:8374211 |
| Sigurdson SL and Ip MM | Casein accumulation by rat mammary epithelial cells grown within a reconstituted basement membrane is modulated by fatty acids in a hormone- and time-dependent manner. | 1993 | Exp. Cell Res. | pmid:8375465 |
| Kirchgessner M and Müller HL | [The effect of palmitic, oleic and linoleic acids on thermogenesis in the model experiment in sows]. | 1993 | Z Ernahrungswiss | pmid:8379216 |
| Feunekes GI et al. | Relative and biomarker-based validity of a food-frequency questionnaire estimating intake of fats and cholesterol. | 1993 | Am. J. Clin. Nutr. | pmid:8379504 |
| James MJ et al. | Simple relationships exist between dietary linoleate and the n-6 fatty acids of human neutrophils and plasma. | 1993 | Am. J. Clin. Nutr. | pmid:8379505 |
| Brinkmeier H et al. | Specific modifications of the membrane fatty acid composition of human myotubes and their effects on the muscular sodium channels. | 1993 | Biochim. Biophys. Acta | pmid:8380720 |
| Tisdale MJ | Mechanism of lipid mobilization associated with cancer cachexia: interaction between the polyunsaturated fatty acid, eicosapentaenoic acid, and inhibitory guanine nucleotide-regulatory protein. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8380931 |
| Poisson JP et al. | Effect of salt-loading and spontaneous hypertension on in vitro metabolism of [1-14C]linoleic and [2-14C]dihomo-gamma-linolenic acids. | 1993 | Biochem. Med. Metab. Biol. | pmid:8382502 |
| Soliven B et al. | Arachidonic acid and its metabolites increase Cai in cultured rat oligodendrocytes. | 1993 | Am. J. Physiol. | pmid:8384786 |
| Horrobin DF | Fatty acid metabolism in health and disease: the role of delta-6-desaturase. | 1993 | Am. J. Clin. Nutr. | pmid:8386433 |
| Reddy AS et al. | Isolation of a delta 6-desaturase gene from the cyanobacterium Synechocystis sp. strain PCC 6803 by gain-of-function expression in Anabaena sp. strain PCC 7120. | 1993 | Plant Mol. Biol. | pmid:8389613 |
| Turley CP and Brewster MA | Alpha-tocopherol protects against a reduction in adenosylcobalamin in oxidatively stressed human cells. | 1993 | J. Nutr. | pmid:8391565 |
| Laihia JK et al. | Lucigenin and linoleate enhanced chemiluminescent assay for superoxide dismutase activity. | 1993 | Free Radic. Biol. Med. | pmid:8394267 |
| Reid G | Metabolic disorders of cattle. | 1993 | Med. Hypotheses | pmid:8394500 |
| De Antueno RJ et al. | Metabolism of radiolabelled 18:2n-6 and 18:3n-6 by NIH-3T3 cells and the DT subclone. | 1993 Jul-Aug | Anticancer Res. | pmid:8394680 |
| Emken EA et al. | Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans. | 1993 | Biochim. Biophys. Acta | pmid:8399342 |
| Baykousheva S | Metabolism of [1-14C]linoleic acid in human promyelocytic leukemia HL-60 cells grown and differentiated in serum-free medium. | 1993 | Cancer Lett. | pmid:8402565 |
| Hatala MA et al. | Characterization of phospholipase A2 activity in MDA-MB-435 human breast cancer cells. | 1993 | Cancer Lett. | pmid:8402571 |
| Rose DP et al. | Effect of diets containing different levels of linoleic acid on human breast cancer growth and lung metastasis in nude mice. | 1993 | Cancer Res. | pmid:8402646 |
| Toborek M and Hennig B | Vitamin E attenuates induction of elastase-like activity by tumor necrosis factor-alpha, cholestan-3 beta,5 alpha,6 beta-triol and linoleic acid in cultured endothelial cells. | 1993 | Clin. Chim. Acta | pmid:8403435 |
| Wolever TM | Comments on "Treatment of diabetic neuropathy with gamma-linolenic acid" by The gamma-Linolenic Multicenter Trial Group. | 1993 | Diabetes Care | pmid:8404440 |
| Kleinveld HA et al. | Oxidation resistance, oxidation rate, and extent of oxidation of human low-density lipoprotein depend on the ratio of oleic acid content to linoleic acid content: studies in vitamin E deficient subjects. | 1993 | Free Radic. Biol. Med. | pmid:8406127 |
| Keler T and Sorof S | Growth promotion of transfected hepatoma cells by liver fatty acid binding protein. | 1993 | J. Cell. Physiol. | pmid:8408240 |
| Seidelin KN et al. | Percentage distribution of fatty acids in subcutaneous adipose tissue of patients with peptic ulcer disease. | 1993 | Am. J. Clin. Nutr. | pmid:8416668 |
| de Waard P et al. | Heteronuclear NMR analysis of unsaturated fatty acids in poly(3-hydroxyalkanoates). Study of beta-oxidation in Pseudomonas putida. | 1993 | J. Biol. Chem. | pmid:8416939 |
| Cominacini L et al. | Determination of lipid hydroperoxides in native low-density lipoprotein by a chemiluminescent flow-injection assay. | 1993 | Biochim. Biophys. Acta | pmid:8418885 |
| Bandyopadhyay GK et al. | Role of polyunsaturated fatty acids as signal transducers: amplification of signals from growth factor receptors by fatty acids in mammary epithelial cells. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8424125 |
| Blair IA et al. | Dietary modification of omega 6 fatty acid intake and its effect on urinary eicosanoid excretion. | 1993 | Am. J. Clin. Nutr. | pmid:8424383 |
| Oliw EH et al. | Bis-allylic hydroxylation of polyunsaturated fatty acids by hepatic monooxygenases and its relation to the enzymatic and nonenzymatic formation of conjugated hydroxy fatty acids. | 1993 | Arch. Biochem. Biophys. | pmid:8424677 |
| Deigner HP and Dresel HA | Effect of platelet activating factor on the kinetics of LDL oxidation in vitro. | 1993 | FEBS Lett. | pmid:8425606 |
| Reaven P et al. | Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects. | 1993 | J. Clin. Invest. | pmid:8432867 |
| Callaghan R et al. | Increased accumulation of drugs in a multidrug resistant cell line by alteration of membrane biophysical properties. | 1993 | Biochim. Biophys. Acta | pmid:8435444 |
| Abbey M et al. | Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation. | 1993 | Am. J. Clin. Nutr. | pmid:8438773 |
| Jones AL et al. | Temperature-induced membrane-lipid adaptation in Acanthamoeba castellanii. | 1993 | Biochem. J. | pmid:8439295 |
| Terada N et al. | Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes. | 1993 | Exp. Cell Res. | pmid:8440323 |
| Clark RM and Hundrieser KE | A lack of correlation among fatty acids associated with different lipid classes in human milk. | 1993 | Lipids | pmid:8441341 |
| Batna A et al. | The occurrence of furan fatty acids in Isochrysis sp. and Phaeodactylum tricornutum. | 1993 | Biochim. Biophys. Acta | pmid:8443233 |
| Oliw EH | bis-Allylic hydroxylation of linoleic acid and arachidonic acid by human hepatic monooxygenases. | 1993 | Biochim. Biophys. Acta | pmid:8443245 |
| Kakita N et al. | Induction of gelatinolytic neutral proteinase secretion by lipid peroxide in cultured mesangial cells. | 1993 | Nephron | pmid:8446258 |
| Hong CY et al. | Effect of pravastatin on fatty acid profile of low density lipoprotein in patients with hypercholesterolemia. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8446653 |
| Band AM et al. | The mechanism of arachidonic acid-induced insulin secretion from rat islets of Langerhans. | 1993 | Biochim. Biophys. Acta | pmid:8452880 |
| Vaughan PF et al. | Effect of inhibitors of eicosanoid metabolism on release of [3H]noradrenaline from the human neuroblastoma, SH-SY5Y. | 1993 | J. Neurochem. | pmid:8455030 |
| Lecerf J et al. | Variations in the fatty acid composition of lipid classes from lipoproteins in elderly women. | 1993 | Atherosclerosis | pmid:8457263 |
| Shiff CJ et al. | A trap for the detection of schistosome cercariae. | 1993 | J. Parasitol. | pmid:8459323 |
| van Haaster CM et al. | Formation of prostanoids and hydroxy fatty acids by stimulated peritoneal mast cells: role of the dietary fat type in rat. | 1993 | Biochim. Biophys. Acta | pmid:8466942 |
| Lomnitski L et al. | The interaction between beta-carotene and lipoxygenase in plant and animal systems. | 1993 | Biochim. Biophys. Acta | pmid:8481396 |
| Püttmann M et al. | Fast HPLC determination of serum free fatty acids in the picomole range. | 1993 | Clin. Chem. | pmid:8485873 |
| Sugano M and Koba K | Dietary protein and lipid metabolism: a multifunctional effect. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8489133 |