Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang M et al. | Dietary conjugated linoleic acid protects against end stage disease of systemic lupus erythematosus in the NZB/W F1 mouse. | 2000 | Immunopharmacol Immunotoxicol | pmid:10946824 |
| Magsino CH et al. | Nadolol inhibits reactive oxygen species generation by leukocytes and linoleic acid oxidation. | 2000 | Am. J. Cardiol. | pmid:10946040 |
| Meilhac O et al. | Lipid peroxides induce expression of catalase in cultured vascular cells. | 2000 | J. Lipid Res. | pmid:10946007 |
| Fabbri AA et al. | Early physiological and cytological events induced by wounding in potato tuber. | 2000 | J. Exp. Bot. | pmid:10937703 |
| Zusman I et al. | Transplacental effects of maternal feeding with high fat diets on lipid exchange and response of the splenic lymphoid system in mice offspring exposed to low doses of carcinogen. | 2000 | Int. J. Mol. Med. | pmid:10934300 |
| Kotani A et al. | Determination of plasma free fatty acids by high-performance liquid chromatography with electrochemical detection. | 2000 | Anal. Biochem. | pmid:10933857 |
| Wingler K et al. | Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells. | 2000 | Gastroenterology | pmid:10930377 |
| Dilika F et al. | Antibacterial activity of linoleic and oleic acids isolated from Helichrysum pedunculatum: a plant used during circumcision rites. | 2000 | Fitoterapia | pmid:10925024 |
| Rosella O et al. | Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro. | 2000 | J. Gastroenterol. Hepatol. | pmid:10921416 |
| Ip C et al. | Induction of apoptosis by conjugated linoleic acid in cultured mammary tumor cells and premalignant lesions of the rat mammary gland. | 2000 | Cancer Epidemiol. Biomarkers Prev. | pmid:10919739 |
| Viola G et al. | In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine. | 2000 | Farmaco | pmid:10919085 |
| Kamlage B et al. | Linoleic acid conjugation by human intestinal microorganisms is inhibited by glucose and other substrates in vitro and in gnotobiotic rats. | 2000 | J. Nutr. | pmid:10917922 |
| Jones S et al. | Isomers of conjugated linoleic acid (CLA) are incorporated into egg yolk lipids by CLA-fed laying hens. | 2000 | J. Nutr. | pmid:10917915 |
| Vanella A et al. | L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. | 2000 | Cell Biol. Toxicol. | pmid:10917565 |
| Sakurada K et al. | cis-9,10-Methylenehexadecanoic acid inhibits contractility and actomyosin ATPase activity of guinea pig myocardium. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10913372 |
| Wenger FA et al. | Does alpha-linolenic acid in combination with linoleic acid influence liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters? | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10913224 |
| Cantwell H et al. | The effect of a conjugated linoleic acid on superoxide dismutase, catalase and glutathione peroxidase in oxidatively-challenged liver cells. | 1998 | Biochem. Soc. Trans. | pmid:10909820 |
| O'Shea M et al. | The effect of a conjugated dienoic derivative of linoleic acid on the in vitro growth of MCF-7 and SW480 human cancer cell lines. | 1998 | Biochem. Soc. Trans. | pmid:10909819 |
| Boué C et al. | Trans fatty acids in adipose tissue of French women in relation to their dietary sources. | 2000 | Lipids | pmid:10907791 |
| Groussard C et al. | Free radical scavenging and antioxidant effects of lactate ion: an in vitro study. | 2000 | J. Appl. Physiol. | pmid:10904049 |
| Deva R et al. | Arachidonic acid stimulates cell growth and forms a novel oxygenated metabolite in Candida albicans. | 2000 | Biochim. Biophys. Acta | pmid:10903481 |
| Mizushina Y et al. | Mode analysis of binding of fatty acids to mammalian DNA polymerases. | 2000 | Biochim. Biophys. Acta | pmid:10903472 |
| Vargas F et al. | Studies on the in vitro phototoxicity of the antidiabetes drug glipizide. | 2000 | In Vitr Mol Toxicol | pmid:10900404 |
| Yen GC and Chuang DY | Antioxidant properties of water extracts from Cassia tora L. in relation to the degree of roasting. | 2000 | J. Agric. Food Chem. | pmid:10898619 |
| Freiberger CE et al. | Nutrient content of the edible leaves of seven wild plants from Niger. | 1998 | Plant Foods Hum Nutr | pmid:10890758 |
| Moussa M et al. | Relationship between the fatty acid composition of rat lymphocytes and immune functions. | 2000 | Br. J. Nutr. | pmid:10884721 |
| Tominaga K et al. | Effect of lipid polarization by centrifugation at different developmental stages on post-thaw survival of bovine in vitro produced 16-cell embryos. | 2000 | Theriogenology | pmid:10883852 |
| Gonzalez B et al. | Metabolism of n -9, n -6 and n -3 fatty acids in hepatoma Morris 7777 cells. Preferential accumulation of linoleic acid in cardiolipin. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883061 |
| Loreau O et al. | Large-scale preparation of (9Z,12E)-[1-(13)C]-octadeca-9,12-dienoic acid, (9Z,12Z,15E)-[1-(13)C]-octadeca-9,12,15-trienoic acid and their [1-(13)C] all-cis isomers. | 2000 | Chem. Phys. Lipids | pmid:10878236 |
| Ponec M et al. | Covalently bound lipids in reconstructed human epithelia. | 2000 Mar-Apr | Acta Derm. Venereol. | pmid:10877125 |
| Kumar KV et al. | Oxidant stress and essential fatty acids in patients with risk and established ARDS. | 2000 | Clin. Chim. Acta | pmid:10876008 |
| Latour MA et al. | Effects of conjugated linoleic acid. 2. Embryonic and neonatal growth and circulating lipids. | 2000 | Poult. Sci. | pmid:10875762 |
| Latour MA et al. | Effects of conjugated linoleic acid. 1. Fatty acid modification of yolks and neonatal fatty acid metabolism. | 2000 | Poult. Sci. | pmid:10875761 |
| Decsi T and Koletzko B | Effects of protein-energy malnutrition and human immunodeficiency virus-1 infection on essential fatty acid metabolism in children. | 2000 | Nutrition | pmid:10869902 |
| Watanabe T et al. | Formation of acyl radical in lipid peroxidation of linoleic acid by manganese-dependent peroxidase from Ceriporiopsis subvermispora and Bjerkandera adusta. | 2000 | Eur. J. Biochem. | pmid:10866827 |
| Sehanputri PS and Hill CG | Biotechnology for the production of nutraceuticals enriched in conjugated linoleic acid: II. Multiresponse kinetics of the hydrolysis of corn oil by a Pseudomonas sp. lipase immobilized in a hollow-fiber reactor. | 2000 | Biotechnol. Bioeng. | pmid:10862683 |
| Yoshiki Y et al. | Chemiluminescence and reactive oxygen scavenging activities of the hydrogen peroxide/gallic acid/lactoperoxidase system. | 2000 May-Jun | Luminescence | pmid:10862147 |
| Williams JP et al. | The role of phosphatidylcholine in fatty acid exchange and desaturation in Brassica napus L. leaves. | 2000 | Biochem. J. | pmid:10861220 |
| Kishino T et al. | Changes in liver fatty acid unsaturation after partial hepatectomy in the rat. | 2000 | Lipids | pmid:10858030 |
| Hamberg M | New cyclopentenone fatty acids formed from linoleic and linolenic acids in potato. | 2000 | Lipids | pmid:10858019 |
| Smith JC et al. | Orosensory factors in the ingestion of corn oil/sucrose mixtures by the rat. | 2000 Apr 1-15 | Physiol. Behav. | pmid:10854925 |
| McHowat J and Creer MH | Selective plasmalogen substrate utilization by thrombin-stimulated Ca(2+)-independent PLA(2) in cardiomyocytes. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10843891 |
| Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
| Bloodsworth A et al. | Manganese-porphyrin reactions with lipids and lipoproteins. | 2000 | Free Radic. Biol. Med. | pmid:10832063 |
| Tokumura A et al. | Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase. | 2000 | J. Lipid Res. | pmid:10828088 |
| Azain MJ et al. | Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number. | 2000 | J. Nutr. | pmid:10827208 |
| Peebles ED et al. | Effects of dietary fat type and level on broiler breeder performance. | 2000 | Poult. Sci. | pmid:10824949 |
| Tominaga K et al. | Effect of linoleic acid-albumin on post-thaw survival of in vitro-produced bovine embryos at the 16-cell stage. | 2000 | J. Vet. Med. Sci. | pmid:10823739 |
| Dhiman TR et al. | Conjugated linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acid. | 2000 | J. Dairy Sci. | pmid:10821577 |
| Pham TQ et al. | Antioxidant properties of crocin from Gardenia jasminoides Ellis and study of the reactions of crocin with linoleic acid and crocin with oxygen. | 2000 | J. Agric. Food Chem. | pmid:10820042 |
| Decsi T et al. | Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817286 |
| Lapillonne A et al. | Effects of liver transplantation on long-chain polyunsaturated fatty acid status in infants with biliary atresia. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817283 |
| Blask DE et al. | New insights into melatonin regulation of cancer growth. | 1999 | Adv. Exp. Med. Biol. | pmid:10810531 |
| Wang J and Zhang Y | [Effect of the long chain polyunsaturated fatty acids levels in mothers on fetuses]. | 1998 | Zhonghua Fu Chan Ke Za Zhi | pmid:10806659 |
| Kachhap SK et al. | Effect of omega-6 polyunsaturated fatty acid (linoleic acid) on BRCA1 gene expression in MCF-7 cell line. | 2000 | Cancer Lett. | pmid:10806298 |
| Iwase H et al. | Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase. | 2000 | Free Radic. Biol. Med. | pmid:10802222 |
| Gupta SV and Khosla P | Pork fat and chicken fat similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. | 2000 | J. Nutr. | pmid:10801922 |
| Itokazu N et al. | Bidirectional actions of docosahexaenoic acid on hippocampal neurotransmissions in vivo. | 2000 | Brain Res. | pmid:10799687 |
| Canudas N et al. | Photobiological properties of nabumetone (4-[6-methoxy-2-naphthalenyl]-2-butanone), a novel non-steroidal anti-inflammatory and analgesic agent. | 2000 | Pharmazie | pmid:10798241 |
| Kaya A | Properties and stability of butter oil obtained from milk and yoghurt. | 2000 | Nahrung | pmid:10795582 |
| Mandin O et al. | Volatile compounds from potato-like model systems. | 1999 | J. Agric. Food Chem. | pmid:10794636 |
| McEvoy TG et al. | Fatty acid composition of lipids in immature cattle, pig and sheep oocytes with intact zona pellucida. | 2000 | J. Reprod. Fertil. | pmid:10793638 |
| Kharchenko OV et al. | [Kinetic mechanisms of linoleic acid oxidation by 5-lipoxygenase from Solanum tuberosum L]. | 1999 Jul-Aug | Ukr Biokhim Zh (1999) | pmid:10791055 |
| McCarty MF | Toward a wholly nutritional therapy for type 2 diabetes. | 2000 | Med. Hypotheses | pmid:10783493 |
| Charnock JS | Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780878 |
| Hover CG and Kulkarni AP | A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780874 |
| Talcott ST et al. | Antioxidant changes and sensory properties of carrot puree processed with and without periderm tissue. | 2000 | J. Agric. Food Chem. | pmid:10775391 |
| Liégeois C et al. | Measuring antioxidant efficiency of wort, malt, and hops against the 2,2'-azobis(2-amidinopropane) dihydrochloride-induced oxidation of an aqueous dispersion of linoleic acid. | 2000 | J. Agric. Food Chem. | pmid:10775361 |
| Sasaki T et al. | Dietary docosahexaenoic acid can alter the surface expression of CD4 and CD8 on T cells in peripheral blood. | 2000 | J. Agric. Food Chem. | pmid:10775347 |
| Siefken W et al. | Regulation of cholesterol synthesis by oleic and palmitic acid in keratinocytes. | 2000 | Exp. Dermatol. | pmid:10772388 |
| Kritharides L | Ascorbic acid and copper in linoleate oxidation--Dunkley revisited. | 1999 | Redox Rep. | pmid:10772064 |
| Mogul R et al. | Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase. | 2000 | Biochemistry | pmid:10769137 |
| Littman ED et al. | Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion. | 2000 | Pancreas | pmid:10766451 |
| Yehuda S et al. | Fatty acid mixture counters stress changes in cortisol, cholesterol, and impair learning. | 2000 | Int. J. Neurosci. | pmid:10765992 |
| Mohan IK and Das UN | Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765977 |
| Punchard NA et al. | Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765976 |
| Tomsits E et al. | Effects of early nutrition on free radical formation in VLBW infants with respiratory distress. | 2000 | J Am Coll Nutr | pmid:10763905 |
| MacDonald HB | Conjugated linoleic acid and disease prevention: a review of current knowledge. | 2000 | J Am Coll Nutr | pmid:10759137 |
| Hubbard NE et al. | Reduction of murine mammary tumor metastasis by conjugated linoleic acid. | 2000 | Cancer Lett. | pmid:10755392 |
| Trimborn M et al. | Linoleic acid cytotoxicity to bovine lens epithelial cells: influence of albumin on linoleic acid uptake and cytotoxicity. | 2000 Mar-Jun | Ophthalmic Res. | pmid:10754440 |
| Rubbo H et al. | Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. | 2000 | J. Biol. Chem. | pmid:10753874 |
| Garcia HS et al. | Interesterification (acidolysis) of butterfat with conjugated linoleic acid in a batch reactor. | 2000 | J. Dairy Sci. | pmid:10750090 |
| Whalen MM et al. | Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. | 1999 | Cell. Physiol. Biochem. | pmid:10749996 |
| Larqué E et al. | Dietary trans fatty acids affect the essential fatty-acid concentration of rat milk. | 2000 | J. Nutr. | pmid:10736340 |
| Hudson JA et al. | Identification and enumeration of oleic acid and linoleic acid hydrating bacteria in the rumen of sheep and cows. | 2000 | J. Appl. Microbiol. | pmid:10735997 |
| Clemmesen JO et al. | Plasma phospholipid fatty acid pattern in severe liver disease. | 2000 | J. Hepatol. | pmid:10735619 |
| Hochi S et al. | Effect of linoleic acid-albumin in the culture medium on freezing sensitivity of in vitro-produced bovine morulae. | 1999 | Theriogenology | pmid:10734383 |
| Kemp B et al. | Influence of linoleic/linolenic acid ratio in the diet of periparturient cattle on plasma concentrations of PGF2 alpha metabolite and placental expulsion rate. | 1998 | Theriogenology | pmid:10732036 |
| Draper AJ and Hammock BD | Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. | 2000 | Arch. Biochem. Biophys. | pmid:10729206 |
| Adam O | Linoleic acid - the fall of an angel? | 1999 | Ann. Nutr. Metab. | pmid:10725772 |
| Fidler N et al. | Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women. | 1999 | Ann. Nutr. Metab. | pmid:10725767 |
| Adeyeye EI et al. | Fatty acid composition of six varieties of dehulled African yam bean (Sphenostylis stenocarpa) flour. | 1999 | Int J Food Sci Nutr | pmid:10719567 |
| Baron CP et al. | Peroxidation of linoleate at physiological pH: hemichrome formation by substrate binding protects against metmyoglobin activation by hydrogen peroxide. | 2000 | Free Radic. Biol. Med. | pmid:10719236 |
| Chavali SR and Forse RA | Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10718106 |
| Cox JE et al. | Suppression of food intake, body weight, and body fat by jejunal fatty acid infusions. | 2000 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:10712279 |
| Takahashi N | Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). | 2000 | Biol. Pharm. Bull. | pmid:10706389 |
| Kitts DD et al. | Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. | 1999 | Mol. Cell. Biochem. | pmid:10705999 |
| Shimada A et al. | Phytotoxicity of indole-3-acetic acid produced by the fungus, Pythium aphanidermatum. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10705467 |
| Delmas-Beauvieux MC et al. | Liposomes as fatty acids carriers in isolated rat liver: effect on energy metabolism and on isolated mitochondria activity. | 2000 | MAGMA | pmid:10697225 |
| Martin JC et al. | Effects of conjugated linoleic acid isomers on lipid-metabolizing enzymes in male rats. | 2000 | Lipids | pmid:10695929 |