Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kummerow FA et al. | Trans fatty acids in partially hydrogenated soybean oil inhibit prostacyclin release by endothelial cells in presence of high level of linoleic acid. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17991616 |
| Sammon AM | Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10410386 |
| Yao X et al. | Effects of thyroid hormone status on metabolic pathways of arachidonic acid in mice and humans: A targeted metabolomic approach. | Prostaglandins Other Lipid Mediat. | pmid:25841349 | |
| Rose DP and Connolly JM | Effects of fatty acids and eicosanoid synthesis inhibitors on the growth of two human prostate cancer cell lines. | 1991 | Prostate | pmid:2020620 |
| Cohen LA et al. | Effect of soy protein isolate and conjugated linoleic acid on the growth of Dunning R-3327-AT-1 rat prostate tumors. | 2003 | Prostate | pmid:12518321 |
| Griffiths G et al. | Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. | 1997 | Prostate | pmid:9108883 |
| Connolly JM and Rose DP | Interactions between epidermal growth factor-mediated autocrine regulation and linoleic acid-stimulated growth of a human prostate cancer cell line. | 1992 | Prostate | pmid:1549552 |
| Verlotta A and Trono D | Expression, purification and refolding of active durum wheat (Triticum durum Desf.) secretory phospholipase A2 from inclusion bodies of Escherichia coli. | 2014 | Protein Expr. Purif. | pmid:24925645 |
| Skrzypczak-Jankun E et al. | Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme. | 1997 | Proteins | pmid:9294864 |
| Dobryniewski J et al. | [Biology of essential fatty acids (EFA)]. | 2007 | Prz. Lek. | pmid:17892040 |
| Buydens-Branchey L et al. | Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts. | 2003 | Psychiatry Res | pmid:14500111 |
| Bazinet RP et al. | Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat. | 2005 | Psychopharmacology (Berl.) | pmid:15986187 |
| Cheng G et al. | Relative validity of a 3 d estimated food record in German toddlers. | 2013 | Public Health Nutr | pmid:22874634 |
| Segovia-Siapco G et al. | Validation of a food-frequency questionnaire for measurement of nutrient intake in a dietary intervention study. | 2007 | Public Health Nutr | pmid:17261227 |
| Petrogianni M et al. | Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. | 2014 | Public Health Nutr | pmid:23249766 |
| Cantwell MM et al. | Development and validation of a food-frequency questionnaire for the determination of detailed fatty acid intakes. | 2005 | Public Health Nutr | pmid:15705250 |
| Maqbool A et al. | The skinny on tuna fat: health implications. | 2011 | Public Health Nutr | pmid:21324226 |
| Fremann D et al. | Dietary conjugated linoleic acid (CLA) intake assessment and possible biomarkers of CLA intake in young women. | 2002 | Public Health Nutr | pmid:12001981 |
| Ghisolfi J et al. | Nutrient intakes of children aged 1-2 years as a function of milk consumption, cows' milk or growing-up milk. | 2013 | Public Health Nutr | pmid:23098567 |
| Vinceti M et al. | A population-based case-control study of diet and melanoma risk in northern Italy. | 2005 | Public Health Nutr | pmid:16372927 |