Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Kim SY et al. | S-adenosyl methionine prevents endothelial dysfunction by inducing heme oxygenase-1 in vascular endothelial cells. | 2013 | Mol. Cells | pmid:24046187 |
Ivan M et al. | Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. | 2013 | Br. J. Nutr. | pmid:22850225 |
Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice. | 2013 | Br. J. Nutr. | pmid:22883314 |
Cheng G et al. | Relative validity of a 3 d estimated food record in German toddlers. | 2013 | Public Health Nutr | pmid:22874634 |
Huang X et al. | Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia. | 2013 | Clin. Cancer Res. | pmid:23493348 |
Godinot N et al. | Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice. | 2013 | Neuroscience | pmid:23831422 |
Lai MC et al. | The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. | 2013 | J. Vet. Med. Sci. | pmid:23832628 |
Bartók T et al. | ESI-MS and MS/MS identification of the first ceramide analogues of fumonisin B₠mycotoxin from a Fusarium verticillioides culture following RP-HPLC separation. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23837460 |
Okada Y et al. | Wing (Ib) cells in frog taste discs detect dietary unsaturated fatty acids. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23872318 |
Song Y et al. | Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members. | 2013 | Lipids Health Dis | pmid:23879935 |
Cao AH et al. | Composition of long chain polyunsaturated fatty acids (LC-PUFAs) in different encephalic regions and its association with behavior in spontaneous hypertensive rat (SHR). | 2013 | Brain Res. | pmid:23811335 |
Klein-Wieringa IR et al. | Adipocytes modulate the phenotype of human macrophages through secreted lipids. | 2013 | J. Immunol. | pmid:23817431 |
Hand KV et al. | Examining acute and chronic effects of short- and long-chain fatty acids on peptide YY (PYY) gene expression, cellular storage and secretion in STC-1 cells. | 2013 | Eur J Nutr | pmid:22926626 |
Kälber T et al. | Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. | 2013 | J. Dairy Res. | pmid:23253429 |
Gillingham LG et al. | Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. | 2013 | Am. J. Clin. Nutr. | pmid:23221573 |
Carro M et al. | Linoleic acid stimulates neutral lipid accumulation in lipid droplets of maturing bovine oocytes. | 2013 | Theriogenology | pmid:23273433 |
Nelson RH et al. | Kinetics of saturated, monounsaturated, and polyunsaturated fatty acids in humans. | 2013 | Diabetes | pmid:23274886 |
Gage SH et al. | Functionalization of monodisperse iron oxide NPs and their properties as magnetically recoverable catalysts. | 2013 | Langmuir | pmid:23234434 |
Figueroa V et al. | Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway. | 2013 | Biochim. Biophys. Acta | pmid:23261389 |
Li A et al. | Thermally induced isomerization of linoleic acid in soybean oil. | 2013 | Chem. Phys. Lipids | pmid:23261796 |
Mena J et al. | Linoleic acid increases adhesion, chemotaxis, granule release, intracellular calcium mobilisation, MAPK phosphorylation and gene expression in bovine neutrophils. | 2013 | Vet. Immunol. Immunopathol. | pmid:23267746 |
Li L et al. | A novel galanin receptor 1a gene in zebrafish: tissue distribution, developmental expression roles in nutrition regulation. | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23268327 |
Zlatanov MD et al. | Lipid composition of Castanea sativa Mill. and Aesculus hippocastanum fruit oils. | 2013 | J. Sci. Food Agric. | pmid:23174908 |
McPherson PA et al. | Mechanism for the enhanced peroxidation of linoleic acid by a titanium dioxide/hypochlorite system. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23178466 |
Serna-Marquez N et al. | Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells. | 2013 | Cell Oncol (Dordr) | pmid:23179791 |
Gámez-Meza N et al. | Chemical characterisation of kernels, kernel meals and oils from Jatropha cordata and Jatropha cardiophylla seeds. | 2013 | J. Sci. Food Agric. | pmid:23180465 |
Toral PG et al. | Effect of the inclusion of quebracho tannins in a diet rich in linoleic acid on milk fatty acid composition in dairy ewes. | 2013 | J. Dairy Sci. | pmid:23164228 |
Yang Z and Huffman SL | Modelling linoleic acid and α-linolenic acid requirements for infants and young children in developing countries. | 2013 | Matern Child Nutr | pmid:23167585 |
Zhao Y et al. | Linoleic acid stimulates [Ca2+]i increase in rat pancreatic beta-cells through both membrane receptor- and intracellular metabolite-mediated pathways. | 2013 | PLoS ONE | pmid:23565210 |
Bakır T et al. | Polar paradox revisited: analogous pairs of hydrophilic and lipophilic antioxidants in linoleic acid emulsion containing Cu(II). | 2013 | J. Sci. Food Agric. | pmid:23520052 |
Godovikova TS et al. | Ligand-directed acid-sensitive amidophosphate 5-trifluoromethyl-2'-deoxyuridine conjugate as a potential theranostic agent. | 2013 | Bioconjug. Chem. | pmid:23521072 |
Høstmark AT and Haug A | Percentage oleic acid is inversely related to percentage arachidonic acid in total lipids of rat serum. | 2013 | Lipids Health Dis | pmid:23521743 |
Fujii M et al. | Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice. | 2013 | Exp. Dermatol. | pmid:23528213 |
Shimomura S et al. | Stereoselective synthesis of a promising flower-inducing KODA analog, (9R,12S,13R,15Z)-9-hydroxy-12,13-methylene-10-oxooctadec-15-enoic acid. | 2013 | Biosci. Biotechnol. Biochem. | pmid:23748793 |
Poon JF et al. | In search of catalytic antioxidants--(alkyltelluro)phenols, (alkyltelluro)resorcinols, and bis(alkyltelluro)phenols. | 2013 | J. Org. Chem. | pmid:23701313 |
Chodok P et al. | Identification and functional characterization of two Δ12-fatty acid desaturases associated with essential linoleic acid biosynthesis in Physcomitrella patens. | 2013 | J. Ind. Microbiol. Biotechnol. | pmid:23702573 |
Luo C et al. | Vegetable oil thermosets reinforced by tannin-lipid formulations. | 2013 | Acta Biomater | pmid:22975626 |
Vasudevan C et al. | The effect of parenteral lipid emulsions on pulmonary hemodynamics and eicosanoid metabolites in preterm infants: a pilot study. | 2013 | Nutr Clin Pract | pmid:24177284 |
Herrera-Meza MS et al. | Dietary anhydrous milk fat naturally enriched with conjugated linoleic acid and vaccenic acid modify cardiovascular risk biomarkers in spontaneously hypertensive rats. | 2013 | Int J Food Sci Nutr | pmid:23360131 |
Satoh K | Linoleic acid. A novel mechanism of endothelial cell dysfunction. | 2013 | Circ. J. | pmid:24077059 |
Li KC et al. | [A preliminary study of the inhibitive efficacy of iodized linoleic acid and its fluorodeoxyuridine ester in hepatocellular cancer]. | 2013 | Zhonghua Gan Zang Bing Za Zhi | pmid:24025140 |
Kim JB et al. | Heart failure is associated with impaired anti-inflammatory and antioxidant properties of high-density lipoproteins. | 2013 | Am. J. Cardiol. | pmid:24050409 |
Caligiuri SP et al. | Dietary linoleic acid and α-linolenic acid differentially affect renal oxylipins and phospholipid fatty acids in diet-induced obese rats. | 2013 | J. Nutr. | pmid:23902961 |
Risé P et al. | Different patterns characterize Omega 6 and Omega 3 long chain polyunsaturated fatty acid levels in blood from Italian infants, children, adults and elderly. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23910046 |
Ruparel S et al. | Oxidized linoleic acid metabolite-cytochrome P450 system (OLAM-CYP) is active in biopsy samples from patients with inflammatory dental pain. | 2013 | Pain | pmid:23867730 |
Shinjyo N et al. | Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. | 2013 | J. Neurosci. Res. | pmid:23633391 |
de Oliveira Otto MC et al. | Circulating and dietary omega-3 and omega-6 polyunsaturated fatty acids and incidence of CVD in the Multi-Ethnic Study of Atherosclerosis. | 2013 | J Am Heart Assoc | pmid:24351702 |
Li XP et al. | Linolelaidic acid induces a stronger proliferative effect on human umbilical vein smooth muscle cells compared to elaidic acid. | 2013 | Lipids | pmid:23341188 |
Vukašinović EL et al. | Diapause induces changes in the composition and biophysical properties of lipids in larvae of the European corn borer, Ostrinia nubilalis (Lepidoptera: Crambidae). | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23701990 |
Luo X et al. | Comparison of enzymatic activity of two linoleic acid isomerases expressed in E. coli. | 2013 | Mol. Biol. Rep. | pmid:24062071 |