Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Disease D004194 2 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Dermatitis D003872 30 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Deficiency Diseases D003677 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Coronary Disease D003327 70 associated lipids
Constipation D003248 8 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colitis D003092 69 associated lipids
Cholestasis D002779 23 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Brain Ischemia D002545 89 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cattle Diseases D002418 24 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Carcinoma D002277 18 associated lipids
Cachexia D002100 21 associated lipids
Breast Neoplasms D001943 24 associated lipids
Brain Edema D001929 20 associated lipids
Body Weight D001835 333 associated lipids
Birth Weight D001724 23 associated lipids
Biliary Atresia D001656 4 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Ascites D001201 25 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Aortic Diseases D001018 11 associated lipids
Hypoxia D000860 23 associated lipids
Olfaction Disorders D000857 17 associated lipids
Anorexia D000855 8 associated lipids
Aneurysm D000783 2 associated lipids
Alzheimer Disease D000544 76 associated lipids
Alopecia D000505 14 associated lipids
Alcoholism D000437 27 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Adenocarcinoma D000230 166 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acidosis D000138 13 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Petrogianni M et al. Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. 2014 Public Health Nutr pmid:23249766
Huang X et al. Serum and adipose tissue fatty acid composition as biomarkers of habitual dietary fat intake in elderly men with chronic kidney disease. 2014 Nephrol. Dial. Transplant. pmid:23229929
Armstrong EH et al. Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway. 2014 J. Biol. Chem. pmid:24692551
Corrêa RC et al. Antioxidant and rheological properties of guava jam with added concentrated grape juice. 2014 J. Sci. Food Agric. pmid:23696312
Beavers WN et al. ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: free radical and enzymatic oxidations. 2014 J. Am. Chem. Soc. pmid:25034362
Shimamoto C et al. Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies. 2014 Hum. Mol. Genet. pmid:25027319
Hellstrand S et al. Genetic variation in FADS1 has little effect on the association between dietary PUFA intake and cardiovascular disease. 2014 J. Nutr. pmid:25008580
Hester AG et al. Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans. 2014 J. Biol. Chem. pmid:24962583
Evans SJ et al. Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism. 2014 J Psychiatr Res pmid:24953860
Moate PJ et al. Grape marc reduces methane emissions when fed to dairy cows. 2014 J. Dairy Sci. pmid:24952778
Mesti T et al. Metabolic impact of anti-angiogenic agents on U87 glioma cells. 2014 PLoS ONE pmid:24922514
Herchi W et al. Flaxseed hull: Chemical composition and antioxidant activity during development. 2014 J Oleo Sci pmid:24919478
Woyda-Ploszczyca AM and Jarmuszkiewicz W Different effects of guanine nucleotides (GDP and GTP) on protein-mediated mitochondrial proton leak. 2014 PLoS ONE pmid:24904988
Nadtochiy SM et al. Mitochondrially targeted nitro-linoleate: a new tool for the study of cardioprotection. 2014 Br. J. Pharmacol. pmid:24102583
Arfaoui MO et al. Variation in oil content, fatty acid and phytosterols profile of Onopordum acanthium L. during seed development. 2014 Nat. Prod. Res. pmid:25103576
Huang X et al. Serum fatty acid patterns, insulin sensitivity and the metabolic syndrome in individuals with chronic kidney disease. 2014 J. Intern. Med. pmid:24011327
Choque B et al. Linoleic acid: between doubts and certainties. 2014 Biochimie pmid:23900039
Usami A et al. Characteristic odorants from bailingu oyster mushroom (Pleurotus eryngii var. tuoliensis) and summer oyster mushroom (Pleurotus cystidiosus). 2014 J Oleo Sci pmid:24919476
López-Cervantes J et al. Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. 2014 Int J Food Sci Nutr pmid:24111501
Wennman A et al. Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases. 2014 Arch. Biochem. Biophys. pmid:24857825
López A et al. Compressive mechanical properties and cytocompatibility of bone-compliant, linoleic acid-modified bone cement in a bovine model. 2014 J Mech Behav Biomed Mater pmid:24508711
Larsson N et al. Lipid mediator profiles differ between lung compartments in asthmatic and healthy humans. 2014 Eur. Respir. J. pmid:24036245
Yang Q et al. Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. 2014 BMC Complement Altern Med pmid:25252789
Shimizu N et al. De novo biosynthesis of linoleic acid and its conversion to the hydrocarbon (Z,Z)-6,9-heptadecadiene in the astigmatid mite, Carpoglyphus lactis: incorporation experiments with 13C-labeled glucose. 2014 Insect Biochem. Mol. Biol. pmid:24333472
Oh YT et al. Regulation of hypothalamic-pituitary-adrenal axis by circulating free fatty acids in male Wistar rats: role of individual free fatty acids. 2014 Endocrinology pmid:24424035
Ozdener MH et al. CD36- and GPR120-mediated Ca²⁺ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice. 2014 Gastroenterology pmid:24412488
Hoffman LC et al. Lipid and protein stability and sensory evaluation of ostrich (Struthio camelus) droëwors with the addition of rooibos tea extract (Aspalathus linearis) as a natural antioxidant. 2014 Meat Sci. pmid:24334052
Canetti L et al. Linoleic and alpha linolenic acids ameliorate streptozotocin-induced diabetes in mice. 2014 Arch. Physiol. Biochem. pmid:24320056
Youn K et al. Oleic acid and linoleic acid from Tenebrio molitor larvae inhibit BACE1 activity in vitro: molecular docking studies. 2014 J Med Food pmid:24548007
Ambrozova JV et al. Influence of extractive solvents on lipid and fatty acids content of edible freshwater algal and seaweed products, the green Microalga Chlorella kessleri and the Cyanobacterium Spirulina platensis. 2014 Molecules pmid:24566307
Bazongo P et al. Characteristics, composition and oxidative stability of Lannea microcarpa seed and seed oil. 2014 Molecules pmid:24566330
Ogorodnikova AV et al. Screening of divinyl ether synthase activity in nonphotosynthetic tissue of asparagales. 2013 Mar-Apr Dokl. Biochem. Biophys. pmid:23657662
Thomas CP et al. Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. 2013 Feb-Mar Chem. Phys. Lipids pmid:23352713
Bae WK et al. Docetaxel-loaded thermoresponsive conjugated linoleic acid-incorporated poloxamer hydrogel for the suppression of peritoneal metastasis of gastric cancer. 2013 Biomaterials pmid:23174142
Lin KH et al. Antioxidant activity of herbaceous plant extracts protect against hydrogen peroxide-induced DNA damage in human lymphocytes. 2013 BMC Res Notes pmid:24279749
Cardoso S et al. UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. 2013 J. Bioenerg. Biomembr. pmid:23504111
Stamey Lanier J et al. Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. 2013 Lipids pmid:23504269
Shen W et al. Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice. 2013 J. Lipid Res. pmid:23401602
Jung CH et al. The preventive effect of uncarboxylated osteocalcin against free fatty acid-induced endothelial apoptosis through the activation of phosphatidylinositol 3-kinase/Akt signaling pathway. 2013 Metab. Clin. Exp. pmid:23639572
Cedernaes J et al. Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet. 2013 Lipids Health Dis pmid:23298201
Zamora-Rojas E et al. Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. 2013 Meat Sci. pmid:23793086
Wardhani DH et al. Inhibition kinetics of lipid oxidation of model foods by using antioxidant extract of fermented soybeans. 2013 Food Chem pmid:23561179
Garofalo JM et al. Mouse mammary gland is refractory to the effects of ethanol after natural lactation. 2013 Comp. Med. pmid:23561936
Hein LK et al. Selective reduction of bis(monoacylglycero)phosphate ameliorates the storage burden in a THP-1 macrophage model of Gaucher disease. 2013 J. Lipid Res. pmid:23564732
Franco-Pons N et al. Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis. 2013 Ann. Surg. pmid:22964727
Benbrook CM et al. Organic production enhances milk nutritional quality by shifting fatty acid composition: a United States-wide, 18-month study. 2013 PLoS ONE pmid:24349282
Green DP et al. Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury. 2013 Pain pmid:23891895
Steffen BT et al. n-3 and n-6 Fatty acids are independently associated with lipoprotein-associated phospholipase A2 in the Multi-Ethnic Study of Atherosclerosis. 2013 Br. J. Nutr. pmid:23551952
Del Mar Bibiloni M et al. Dietary factors associated with subclinical inflammation among girls. 2013 Eur J Clin Nutr pmid:24149444
Peters BD et al. Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. 2013 Schizophr Bull pmid:22927668