Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Loizzo MR et al. | In vitro antioxidant and hypoglycemic activities of Ethiopian spice blend Berbere. | 2011 | Int J Food Sci Nutr | pmid:21599464 |
| Kruska N and Reiser G | Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. | 2011 | Neurobiol. Dis. | pmid:21570468 |
| Liu SJ et al. | Effect of ruminal pulse dose of polyunsaturated fatty acids on ruminal microbial populations and duodenal flow and milk profiles of fatty acids. | 2011 | J. Dairy Sci. | pmid:21605768 |
| Palmieri-Thiers C et al. | Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies. | 2011 | Arch. Biochem. Biophys. | pmid:21345329 |
| Kishino S et al. | Linoleic acid isomerase in Lactobacillus plantarum AKU1009a proved to be a multi-component enzyme system requiring oxidoreduction cofactors. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21307591 |
| McFarland DC et al. | Effect of lipids on avian satellite cell proliferation, differentiation and heparan sulfate proteoglycan expression. | 2011 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:21356326 |
| Ranchordas MK et al. | A-z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 23. | 2011 | Br J Sports Med | pmid:21743106 |
| Kikalishvili BIu et al. | [The most biological important constances of Rkatsiteli grape oil and its effect as a 5% and 10% food-additive]. | 2011 | Georgian Med News | pmid:21778549 |
| Beker BY et al. | Antioxidant protective effect of flavonoids on linoleic acid peroxidation induced by copper(II)/ascorbic acid system. | 2011 | Chem. Phys. Lipids | pmid:21925488 |
| Lin YH et al. | Altered essential fatty acid metabolism and composition in rat liver, plasma, heart and brain after microalgal DHA addition to the diet. | 2011 | J. Nutr. Biochem. | pmid:21111595 |
| Briend A et al. | Fatty acid status in early life in low-income countries--overview of the situation, policy and research priorities. | 2011 | Matern Child Nutr | pmid:21366873 |
| Blasbalg TL et al. | Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. | 2011 | Am. J. Clin. Nutr. | pmid:21367944 |
| Edris AE | The chemical composition and the content of volatile oil: potential factors that can contribute to the oxidative stability of Nigella sativa L. crude oil. | 2011 | J Diet Suppl | pmid:22432633 |
| Salem N and Kuratko CN | Lack of evidence for increased α-linolenic acid metabolism in vegetarians. | 2011 | Am. J. Clin. Nutr. | pmid:21430120 |
| McCusker MM and Grant-Kels JM | Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. | 2010 Jul-Aug | Clin. Dermatol. | pmid:20620762 |
| NaÄdina VP et al. | [Changes in lipid composition of human plasma and erythrocyte membranes due to sodium hydroxybutyrate and normobaric hyperoxia during bed rest]. | 2010 Jan-Feb | Aviakosm Ekolog Med | pmid:20804001 |
| Zovko Koncić M et al. | Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488218 |
| Hajlaoui H et al. | Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488223 |
| Jung S et al. | Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers. | 2010 | Meat Sci. | pmid:20609528 |
| Feldstein AE et al. | Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2010 | J. Lipid Res. | pmid:20631297 |
| Khiaosa-ard R et al. | Methods of emulsifying linoleic acid in biohydrogenation studies in vitro may bias the resulting fatty acid profiles. | 2010 | Lipids | pmid:20582723 |
| Delhanty PJ et al. | Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20587751 |
| Ross RA et al. | Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20647558 |
| Ohmori H et al. | Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1. | 2010 | Pathobiology | pmid:20616616 |
| Gao F et al. | Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats. | 2010 | J. Lipid Res. | pmid:20622136 |
| Herdmann A et al. | Effect of dietary n-3 and n-6 PUFA on lipid composition of different tissues of German Holstein bulls and the fate of bioactive fatty acids during processing. | 2010 | J. Agric. Food Chem. | pmid:20597504 |
| Zaman MM et al. | Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice. | 2010 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:20656894 |
| Livraghi S et al. | Decreasing the oxidative potential of TiO(2) nanoparticles through modification of the surface with carbon: a new strategy for the production of safe UV filters. | 2010 | Chem. Commun. (Camb.) | pmid:20938530 |
| Caroprese M et al. | Flaxseed supplementation improves fatty acid profile of cow milk. | 2010 | J. Dairy Sci. | pmid:20494167 |
| Wien M et al. | Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. | 2010 | Lipids | pmid:20496049 |
| Can-Karabulut DC et al. | Influence of experimental provisional cements containing zeolite, bone hydroxyapatite and linoleic Acid on bond strength of composite to dentin in vitro. | 2010 | J Adhes Dent | pmid:20157651 |
| Biro A et al. | Complement protein C1q recognizes enzymatically modified low-density lipoprotein through unesterified fatty acids generated by cholesterol esterase. | 2010 | Biochemistry | pmid:20166680 |
| Maia MR et al. | Toxicity of unsaturated fatty acids to the biohydrogenating ruminal bacterium, Butyrivibrio fibrisolvens. | 2010 | BMC Microbiol. | pmid:20167098 |
| Sarikurkcu C et al. | Evaluation of metal concentration and antioxidant activity of three edible mushrooms from Mugla, Turkey. | 2010 | Food Chem. Toxicol. | pmid:20167240 |
| Vukovic N et al. | An efficient synthesis and antioxidant properties of novel imino and amino derivatives of 4-hydroxy coumarins. | 2010 | Arch. Pharm. Res. | pmid:20191339 |
| Hirai S et al. | Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco. | 2010 | FEBS J. | pmid:20180844 |
| Pauloin A et al. | Oleate and linoleate stimulate degradation of β-casein in prolactin-treated HC11 mouse mammary epithelial cells. | 2010 | Cell Tissue Res. | pmid:20182891 |
| Gammill W et al. | Comparative study of high-linoleic acid vegetable oils for the production of conjugated linoleic acid. | 2010 | J. Agric. Food Chem. | pmid:20136082 |
| Harris W | Omega-6 and omega-3 fatty acids: partners in prevention. | 2010 | Curr Opin Clin Nutr Metab Care | pmid:20145438 |
| Goebel AS et al. | Dermal targeting using colloidal carrier systems with linoleic acid. | 2010 | Eur J Pharm Biopharm | pmid:20170728 |
| Thornhill JA et al. | Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. | 2010 | Parasitology | pmid:20128942 |
| Dailey MJ et al. | Nutrient specific feeding and endocrine effects of jejunal infusions. | 2010 | Obesity (Silver Spring) | pmid:20134410 |
| Combet E et al. | Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20112267 |
| Jernerén F et al. | Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus. | 2010 | Biochim. Biophys. Acta | pmid:20045744 |
| Paraszkiewicz K et al. | Lipid peroxidation in the fungus Curvularia lunata exposed to nickel. | 2010 | Arch. Microbiol. | pmid:20047047 |
| Esmaeili MA and Sonboli A | Antioxidant, free radical scavenging activities of Salvia brachyantha and its protective effect against oxidative cardiac cell injury. | 2010 | Food Chem. Toxicol. | pmid:20036303 |
| da Silva JK et al. | Essential oil composition, antioxidant capacity and antifungal activity of Piper divaricatum. | 2010 | Nat Prod Commun | pmid:20420331 |
| Li Y et al. | Bone mineral content is positively correlated to n-3 fatty acids in the femur of growing rats. | 2010 | Br. J. Nutr. | pmid:20420751 |
| Edwards SJ et al. | Impact of distal mutation on hydrogen transfer interface and substrate conformation in soybean lipoxygenase. | 2010 | J Phys Chem B | pmid:20423074 |
| Patwardhan AM et al. | Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents. | 2010 | J. Clin. Invest. | pmid:20424317 |
| Brown DA and Passmore GM | Some new insights into the molecular mechanisms of pain perception. | 2010 | J. Clin. Invest. | pmid:20424321 |
| Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Bradbury KE et al. | The serum fatty acids myristic acid and linoleic acid are better predictors of serum cholesterol concentrations when measured as molecular percentages rather than as absolute concentrations. | 2010 | Am. J. Clin. Nutr. | pmid:19955401 |
| Lábaque MC et al. | Effect of age and body weight of Greater Rhea (Rhea americana) females on egg number, size and composition. | 2010 | Br. Poult. Sci. | pmid:21161792 |
| Zidi A et al. | Pleiotropic effects of the goat prolactin receptor genotype on milk fatty acid composition. | 2010 | Domest. Anim. Endocrinol. | pmid:20399061 |
| Peoples GE and McLennan PL | Dietary fish oil reduces skeletal muscle oxygen consumption, provides fatigue resistance and improves contractile recovery in the rat in vivo hindlimb. | 2010 | Br. J. Nutr. | pmid:20691135 |
| Deiana M et al. | Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells. | 2010 | Food Chem. Toxicol. | pmid:20691238 |
| Huang CB et al. | Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. | 2010 | Arch. Oral Biol. | pmid:20541177 |
| Köse EO et al. | Chemical composition, antimicrobial and antioxidant activities of the essential oils of Sideritis erythrantha Boiss. and Heldr. (var. erythrantha and var. cedretorum P.H. Davis) endemic in Turkey. | 2010 | Food Chem. Toxicol. | pmid:20670669 |
| Strandvik B | Fatty acid metabolism in cystic fibrosis. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20673710 |
| Rodrigues HG et al. | Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. | 2010 | Lipids | pmid:20730605 |
| Tel G et al. | Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities. | 2010 | Food Chem. Toxicol. | pmid:20732375 |
| Takahashi S et al. | The occurrence of renin inhibitor in rice: isolation, identification, and structure-function relationship. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20699562 |
| Vij N | Linoleic acid supplement in cystic fibrosis: friend or foe? | 2010 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:20709729 |
| Aziz AA et al. | Increasing Dietary alpha-linolenic acid enhances tissue levels of long-chain n-3 PUFA when linoleic acid intake is low in hamsters. | 2010 | Ann. Nutr. Metab. | pmid:20714137 |
| Gutiérrez-Correa J | Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. | 2010 | Free Radic. Res. | pmid:20815787 |
| Bolton B and Halpern BP | Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. | 2010 | Chem. Senses | pmid:20100787 |
| Lu XF et al. | Colorectal cancer cell growth inhibition by linoleic acid is related to fatty acid composition changes. | 2010 | J Zhejiang Univ Sci B | pmid:21121070 |
| Luo H et al. | The In vitro antioxidant properties of chinese highland lichens. | 2010 | J. Microbiol. Biotechnol. | pmid:21124057 |
| Olszewska MA et al. | Assessment of the content of phenolics and antioxidant action of inflorescences and leaves of selected species from the genus Sorbus sensu stricto. | 2010 | Molecules | pmid:21127463 |
| Gotoh N et al. | Highly unsaturated fatty acid might act as an antioxidant in emulsion system oxidized by azo compound. | 2010 | J Oleo Sci | pmid:21099140 |
| Guo JJ and Hu CH | Mechanism of chain termination in lipid peroxidation by carotenes: a theoretical study. | 2010 | J Phys Chem B | pmid:21105679 |
| Wu TC et al. | Fatty acid composition of Taiwanese human milk. | 2010 | J Chin Med Assoc | pmid:21093826 |
| Safarinejad MR et al. | Relationship of omega-3 and omega-6 fatty acids with semen characteristics, and anti-oxidant status of seminal plasma: a comparison between fertile and infertile men. | 2010 | Clin Nutr | pmid:19666200 |
| Panagiotakos DB et al. | Fatty acids intake and depressive symptomatology in a Greek sample: an epidemiological analysis. | 2010 | J Am Coll Nutr | pmid:21677122 |
| West SG et al. | Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. | 2010 | J Am Coll Nutr | pmid:21677123 |
| Demir AS and Talpur FN | Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid. | 2010 | J. Agric. Food Chem. | pmid:20058923 |
| Zulkifli RM et al. | Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols. | 2010 | J. Anim. Sci. | pmid:20382866 |
| DomÃnguez T et al. | Increasing omega-3 desaturase expression in tomato results in altered aroma profile and enhanced resistance to cold stress. | 2010 | Plant Physiol. | pmid:20382895 |
| Kamkar A et al. | The antioxidative effect of Iranian Mentha pulegium extracts and essential oil in sunflower oil. | 2010 | Food Chem. Toxicol. | pmid:20385193 |
| Sarikurkcu C et al. | Essential oil composition and antioxidant activity of Thymus longicaulis C. Presl subsp. longicaulis var. longicaulis. | 2010 | Food Chem. Toxicol. | pmid:20385197 |
| Marei WF et al. | Impact of linoleic acid on bovine oocyte maturation and embryo development. | 2010 | Reproduction | pmid:20215338 |
| Litvinov D et al. | Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. | 2010 | Atherosclerosis | pmid:19880116 |
| Wan ZX et al. | Lipid content and fatty acids composition of mature human milk in rural North China. | 2010 | Br. J. Nutr. | pmid:19825220 |
| Li Z et al. | Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase. | 2010 | Bioresour. Technol. | pmid:19833506 |
| Friesen RW and Innis SM | Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. | 2010 | Am. J. Clin. Nutr. | pmid:19923368 |
| Runyon JB et al. | Parasitism by Cuscuta pentagona sequentially induces JA and SA defence pathways in tomato. | 2010 | Plant Cell Environ. | pmid:19930126 |
| Schwartz J et al. | Dietary intake and plasma concentrations of PUFA and LC-PUFA in breastfed and formula fed infants under real-life conditions. | 2010 | Eur J Nutr | pmid:19851802 |
| Martin H | Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. | 2010 | Mutat. Res. | pmid:20973164 |
| Benammar C et al. | Zizyphus lotus L. (Desf.) modulates antioxidant activity and human T-cell proliferation. | 2010 | BMC Complement Altern Med | pmid:20868496 |
| Lu X et al. | Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. | 2010 | Lipids Health Dis | pmid:20868498 |
| Macouzet M et al. | Genetic and functional aspects of linoleate isomerase in Lactobacillus acidophilus. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20461509 |
| McKay DL et al. | Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study. | 2010 | Nutr J | pmid:20462428 |
| Salehipour M et al. | Polyunsaturated fatty acids and modulation of cholesterol homeostasis in THP-1 macrophage-derived foam cells. | 2010 | Int J Mol Sci | pmid:21151462 |
| Rodrigues AS et al. | Proton leak modulation in testicular mitochondria affects reactive oxygen species production and lipid peroxidation. | 2010 | Cell Biochem. Funct. | pmid:20235330 |
| Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |
| Zabielski P et al. | The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20599517 |
| Zengin G et al. | In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey. | 2010 | Food Chem. Toxicol. | pmid:20600531 |
| Shen Q et al. | Antioxidant activity in vitro of the selenium-contained protein from the Se-enriched Bifidobacterium animalis 01. | 2010 | Anaerobe | pmid:20601030 |