Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kelavkar U et al. | 15-lipoxygenase-1 overexpression in prostate adenocarcinoma. | 2002 | Adv. Exp. Med. Biol. | pmid:12664577 |
Egashira Y et al. | Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serum. | 2003 | Adv. Exp. Med. Biol. | pmid:15206789 |
Sharma HM et al. | Effect of MAK-4 and MAK-5 on endothelial cell and soyabean lipoxygenase-induced LDL oxidation. | 1994 | Adv. Exp. Med. Biol. | pmid:7771286 |
Tanaka R et al. | Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. | 2012 | Adv. Exp. Med. Biol. | pmid:22259110 |
Louw L et al. | Impairment in the fatty acid composition of keloids. | 1997 | Adv. Exp. Med. Biol. | pmid:9547645 |
Louw L et al. | Linoleic acid levels in cutaneous tumors with different growth patterns as an additional sensitive diagnostic feature. | 1997 | Adv. Exp. Med. Biol. | pmid:9547646 |
Louw L et al. | The importance of linoleic acid in the total fatty acid compositions of benign and malignant neuroglial tumors. | 1997 | Adv. Exp. Med. Biol. | pmid:9547647 |
Marosvölgyi T et al. | Trans isomeric and LCPUFA are inversely correlated in erythrocyte membrane lipids at mid-gestation. | 2009 | Adv. Exp. Med. Biol. | pmid:19536675 |
Agostoni C et al. | Long-chain polyunsaturated fatty acid concentrations in human hindmilk are constant throughout twelve months of lactation. | 2001 | Adv. Exp. Med. Biol. | pmid:11787678 |
Demmelmair H et al. | Investigation of long-chain polyunsaturated fatty acid metabolism in lactating women by means of stable isotope techniques. | 2001 | Adv. Exp. Med. Biol. | pmid:11787680 |
Fidler N et al. | Fat content and fatty acid composition of fresh, pasteurized, or sterilized human milk. | 2001 | Adv. Exp. Med. Biol. | pmid:11787720 |
Blask DE et al. | New insights into melatonin regulation of cancer growth. | 1999 | Adv. Exp. Med. Biol. | pmid:10810531 |
Louw L et al. | Keloids: peripheral and central differences in cell morphology and fatty acid compositions of lipids. | 1997 | Adv. Exp. Med. Biol. | pmid:9322000 |
GIBSON DM and ALLMANN DW | ADAPTIVE CHANGES IN FATTY ACID BIOSYNTHESIS. | 1963 | Adv. Enzyme Regul. | pmid:14190353 |
Cook ME | Nutritional effects on vaccination. | 1999 | Adv Vet Med | pmid:9890009 |
Birnbaum L | Addition of conjugated linoleic acid to a herbal anticellulite pill. | 2001 Sep-Oct | Adv Ther | pmid:11783459 |
Guyenet SJ and Carlson SE | Increase in adipose tissue linoleic acid of US adults in the last half century. | 2015 | Adv Nutr | pmid:26567191 |
Whelan J and Fritsche K | Linoleic acid. | 2013 | Adv Nutr | pmid:23674797 |
Ermidou-Pollet S et al. | Influence of subcutaneous injection of essential fatty acids on the stress-induced modifications of rat platelet aggregation and membrane lipid composition. | 2005 | Acta. Biol. Hung. | pmid:16196200 |
Arawwawala M et al. | In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. | 2011 | Acta. Biol. Hung. | pmid:21840826 |