Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sheaff Greiner RC et al. | Linoleate, alpha-linolenate, and docosahexaenoate recycling into saturated and monounsaturated fatty acids is a major pathway in pregnant or lactating adults and fetal or infant rhesus monkeys. | 1996 | J. Lipid Res. | pmid:9017518 |
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Das I et al. | Effects of aspirin and garlic on cyclooxygenase-induced chemiluminescence in human term placenta. | 1997 | Biochem. Soc. Trans. | pmid:9056997 |
Kühn H et al. | In vivo action of 15-lipoxygenase in early stages of human atherogenesis. | 1997 | J. Clin. Invest. | pmid:9062346 |
Roy SK and Kulkarni AP | Isolation and some properties of dioxygenase and co-oxidase activities of adult human liver cytosolic lipoxygenase. | 1996 | J. Biochem. Toxicol. | pmid:9062846 |
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Butler M et al. | Unsaturated fatty acids enhance cell yields and perturb the energy metabolism of an antibody-secreting hybridoma. | 1997 | Biochem. J. | pmid:9065785 |
Cunningham DC et al. | Proliferative responses of normal human mammary and MCF-7 breast cancer cells to linoleic acid, conjugated linoleic acid and eicosanoid synthesis inhibitors in culture. | 1997 Jan-Feb | Anticancer Res. | pmid:9066651 |
Reddy N et al. | Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070230 |