Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Retinal Degeneration D012162 9 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Pellagra D010383 1 associated lipids
Tinea Versicolor D014010 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Retinoblastoma D012175 12 associated lipids
Liposarcoma D008080 1 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Haemophilus Infections D006192 3 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Helicobacter Infections D016481 21 associated lipids
Onchocerciasis D009855 1 associated lipids
Infertility D007246 3 associated lipids
Melanosis D008548 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Refractive Errors D012030 1 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Coronary Restenosis D023903 10 associated lipids
Wounds, Penetrating D014950 10 associated lipids
Hypokinesia D018476 2 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Circoviridae Infections D018173 2 associated lipids
Lymphopenia D008231 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Constipation D003248 8 associated lipids
Choroidal Neovascularization D020256 5 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Lactose Intolerance D007787 2 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Mucositis D052016 7 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Iwase H et al. Effect of monochlorohydrins of linoleic acid on guinea-pig cardiac papillary muscles. 1997 Biochem. Biophys. Res. Commun. pmid:9070266
Belury MA and Kempa-Steczko A Conjugated linoleic acid modulates hepatic lipid composition in mice. 1997 Lipids pmid:9075211
Barclay LR et al. Photo-initiated peroxidation of lipids in micelles by azaaromatics. 1997 Lipids pmid:9076660
Schneider C et al. Analysis of lipoxygenase-derived fatty acid hydroperoxides by electrospray ionization tandem mass spectrometry. 1997 Lipids pmid:9076671
Iwase H et al. Formation of leukotoxin (9,10-epoxy-12-octadecenoic acid) during the autoxidation of phospholipids promoted by hemoproteins. 1997 Biochim. Biophys. Acta pmid:9084498
Yamaki T et al. Acute and reversible fatty metamorphosis of cultured rat hepatocytes. 1997 Feb-Mar Pathol. Int. pmid:9088028
Ikeda I et al. Effect of dietary linoleic, alpha-linolenic and arachidonic acids on lipid metabolism, tissue fatty acid composition and eicosanoid production in rats. 1996 J. Nutr. Sci. Vitaminol. pmid:9089480
Hayes KC The linoleic acid content of test diets must be carefully monitored in cholesterol studies. 1997 Am. J. Clin. Nutr. pmid:9094899
Nishizaki T et al. Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid. 1997 Brain Res. pmid:9099812
Griffiths G et al. Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. 1997 Prostate pmid:9108883
Nieuwenhuizen WF et al. Lipoxygenase is irreversibly inactivated by the hydroperoxides formed from the enynoic analogues of linoleic acid. 1997 Biochemistry pmid:9109655
Ip C et al. Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis. 1997 Carcinogenesis pmid:9111211
Fukushima M et al. Comparative hypocholesterolemic effects of capybara (Hydrochoerus hydrochaeris dabbenei) oil, horse oil, and sardine oil in cholesterol-fed rats. 1997 Lipids pmid:9113627
Goldreich D et al. The effect of retinol and retinoic acids on lipoxygenase activity. 1997 Int J Vitam Nutr Res pmid:9119612
Ip C and Scimeca JA Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis. 1997 Nutr Cancer pmid:9121939
Schneider C et al. A fatty acid alpha-ketol, a product of the plant lipoxygenase pathway, is oxidized to 3(Z)-dodecendioic acid by a bacterial monooxygenase. 1997 Biochem. Biophys. Res. Commun. pmid:9125182
Bourre JM et al. Possible role of the choroid plexus in the supply of brain tissue with polyunsaturated fatty acids. 1997 Neurosci. Lett. pmid:9132678
Visonneau S et al. Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. 1997 Mar-Apr Anticancer Res. pmid:9137436
Wong MW et al. Effects of dietary conjugated linoleic acid on lymphocyte function and growth of mammary tumors in mice. 1997 Mar-Apr Anticancer Res. pmid:9137439
Chew BP et al. Effects of conjugated dienoic derivatives of linoleic acid and beta-carotene in modulating lymphocyte and macrophage function. 1997 Mar-Apr Anticancer Res. pmid:9137456