Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Thorax (1)
- Am. J. Physiol., Cell Physiol. (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Akeo K and Hiramitsu T | Changes in lipid peroxide level in retinal pigment epithelial cells in vitro upon addition of linoleic acids or linoleic acid hydroperoxides under varying concentrations of oxygen. | 1998 | Pigment Cell Res. | pmid:9877104 |
| Matsuba S et al. | Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888206 |
| Tsimikas S et al. | LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:9888874 |
| Cook ME | Nutritional effects on vaccination. | 1999 | Adv Vet Med | pmid:9890009 |
| Hennig B et al. | Linoleic acid amplifies polychlorinated biphenyl-mediated dysfunction of endothelial cells. | 1999 | J. Biochem. Mol. Toxicol. | pmid:9890193 |
| O'Donnell VB et al. | Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion. | 1999 | Chem. Res. Toxicol. | pmid:9894022 |
| Mahfouz MM and Kummerow FA | Hydrogenated fat high in trans monoenes with an adequate level of linoleic acid has no effect on prostaglandin synthesis in rats. | 1999 | J. Nutr. | pmid:9915870 |
| Hayek MG et al. | Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. | 1999 | J. Nutr. | pmid:9915872 |
| Satory DL and Smith SB | Conjugated linoleic acid inhibits proliferation but stimulates lipid filling of murine 3T3-L1 preadipocytes. | 1999 | J. Nutr. | pmid:9915881 |
| Pohl CH et al. | Oxylipin formation in fungi: biotransformation of arachidonic acid to 3-hydroxy-5,8-tetradecadienoic acid by Mucor genevensis. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9918790 |
| Allman-Farinelli MA et al. | Comparison of the effects of two low fat diets with different alpha-linolenic:linoleic acid ratios on coagulation and fibrinolysis. | 1999 | Atherosclerosis | pmid:9920517 |
| Natella F et al. | Oxidative modification of human low-density lipoprotein by horseradish peroxidase in the absence of hydrogen peroxide. | 1998 | Free Radic. Res. | pmid:9925035 |
| Kalivianakis M et al. | Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. | 1999 | Am. J. Clin. Nutr. | pmid:9925134 |
| Began G et al. | Inhibition of lipoxygenase 1 by phosphatidylcholine micelles-bound curcumin. | 1998 | Lipids | pmid:9930409 |
| Chyb S et al. | Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. | 1999 | Nature | pmid:9930700 |
| Toborek M and Hennig B | The role of linoleic acid in endothelial cell gene expression. Relationship to atherosclerosis. | 1998 | Subcell. Biochem. | pmid:9932524 |
| Black PN | The prevalence of allergic disease and linoleic acid in the diet. | 1999 | J. Allergy Clin. Immunol. | pmid:9949330 |
| Rao MS et al. | Yield, protein, and oil quality of soybean genotypes selected for tofu production. | 1998 | Plant Foods Hum Nutr | pmid:9950085 |
| Zhou L and Nilsson A | Fasting increases tissue uptake and interconversion of plasma unesterified linoleic acid in guinea pigs. | 1999 | Biochim. Biophys. Acta | pmid:9989279 |
| Sasaki T et al. | Effects of dietary docosahexaenoic acid on surface molecules involved in T cell proliferation. | 1999 | Biochim. Biophys. Acta | pmid:9989281 |