| MeSH term | MeSH ID | Detail |
|---|---|---|
| Reperfusion Injury | D015427 | 65 associated lipids |
| Child Nutrition Disorders | D015362 | 1 associated lipids |
| Dry Eye Syndromes | D015352 | 10 associated lipids |
| Wounds, Penetrating | D014950 | 10 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Varicose Ulcer | D014647 | 4 associated lipids |
| Varicocele | D014646 | 4 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bafor M et al. | Biosynthesis of vernoleate (cis-12-epoxyoctadeca-cis-9-enoate) in microsomal preparations from developing endosperm of Euphorbia lagascae. | 1993 | Arch. Biochem. Biophys. | pmid:8489257 |
| Naval J et al. | Alternative route for the biosynthesis of polyunsaturated fatty acids in K562 cells. | 1993 | Biochem. J. | pmid:8489510 |
| Budowski P et al. | Linoleic acid in mature milk from Israeli mothers. | 1993 | J. Pediatr. | pmid:8501585 |
| Wey HE et al. | Essential fatty acid deficiency in cultured human keratinocytes attenuates toxicity due to lipid peroxidation. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8511784 |
| Thompson RL et al. | Cigarette smoking, polyunsaturated fats, and coronary heart disease. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8512244 |
| Richter G and Lemser A | [The use of native triticale in poultry. 3. Use in laying hens]. | 1993 | Arch Tierernahr | pmid:8517768 |
| Hudson EA et al. | Kinetics of the inhibition of tumour growth in mice by eicosapentaenoic acid-reversal by linoleic acid. | 1993 | Biochem. Pharmacol. | pmid:8517859 |
| Osawa T et al. | Antioxidative activity of tetrahydrocurcuminoids. | 1995 | Biosci. Biotechnol. Biochem. | pmid:8520105 |
| Nishio H and Mori K | Reinvestigation of the structure of the esterified cerebroside in the epidermis of guinea pigs. | 1995 | Biosci. Biotechnol. Biochem. | pmid:8520108 |
| Arnhold J et al. | The action of hypochlorous acid on phosphatidylcholine liposomes in dependence on the content of double bonds. Stoichiometry and NMR analysis. | 1995 | Chem. Phys. Lipids | pmid:8521532 |
| Abushufa R et al. | Essential fatty acid status in patients on long-term home parenteral nutrition. | 1995 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:8523627 |
| Shen J et al. | Transgenic rabbits with the integrated human 15-lipoxygenase gene driven by a lysozyme promoter: macrophage-specific expression and variable positional specificity of the transgenic enzyme. | 1995 | FASEB J. | pmid:8529842 |
| Wiseman SA et al. | Comparison of the effects of dietary vitamin E on in vivo and in vitro parameters of lipid peroxidation in the rabbit. | 1995 | Free Radic. Biol. Med. | pmid:8529921 |
| Groves BA | Exit linoleic acid too? | 1996 | Lancet | pmid:8531562 |
| Nordenström J et al. | Metabolic effects of infusion of a structured-triglyceride emulsion in healthy subjects. | 1995 May-Jun | Nutrition | pmid:8541695 |
| Siguel EN and Lerman RH | Prevalence of essential fatty acid deficiency in patients with chronic gastrointestinal disorders. | 1996 | Metab. Clin. Exp. | pmid:8544768 |
| Ivanetich KM et al. | Delta 6-desaturase: improved methodology and analysis of the kinetics in a multi-enzyme system. | 1996 | Biochim. Biophys. Acta | pmid:8547334 |
| Mirzoeva OK et al. | Competitive inhibition of the 5-lipoxygenase-catalysed linoleate oxidation by arachidonic and 5-hydroperoxy-eicosatetraenoic acids. | 1995 | FEBS Lett. | pmid:8549743 |
| Bauldry SA et al. | Activation of cytosolic phospholipase A2 in permeabilized human neutrophils. | 1996 | Biochim. Biophys. Acta | pmid:8555268 |
| Luthria DL and Sprecher H | Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. | 1995 | J. Lipid Res. | pmid:8558078 |
| Heiskanen K et al. | Interactions of cis-fatty acids and their anilides with formyl-methionyl-leucyl-phenylalanine, phorbol myristate acetate and dioctanoyl-s,n-glycerol in human leukocytes. | 1995 | Toxicology | pmid:8560489 |
| Ghusain-Choueiri AA and Rath EA | Effect of carbohydrate source on lipid metabolism in lactating mice and on pup development. | 1995 | Br. J. Nutr. | pmid:8562569 |
| Braganza JM et al. | Evidence for early oxidative stress in acute pancreatitis. Clues for correction. | 1995 | Int. J. Pancreatol. | pmid:8568337 |
| Nelson GJ et al. | Low-fat diets do not lower plasma cholesterol levels in healthy men compared to high-fat diets with similar fatty acid composition at constant caloric intake. | 1995 | Lipids | pmid:8569436 |
| Huang YS et al. | N-3 and n-6 fatty acid metabolism in undifferentiated and differentiated human intestine cell line (Caco-2). | 1995 | Mol. Cell. Biochem. | pmid:8569757 |
| desBordes C and Lea MA | Effects of C18 fatty acid isomers on DNA synthesis in hepatoma and breast cancer cells. | 1995 Sep-Oct | Anticancer Res. | pmid:8572595 |
| Demmelmair H et al. | Estimation of arachidonic acid synthesis in full term neonates using natural variation of 13C content. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:8576811 |
| Cao JM et al. | Effect of low levels of dietary fish oil on fatty acid desaturation and tissue fatty acids in obese and lean rats. | 1995 | Lipids | pmid:8577226 |
| Abdel Baset H et al. | Characterization of arachidonic-acid-metabolizing enzymes in adult Schistisoma mansoni. | 1995 | Mol. Biochem. Parasitol. | pmid:8577345 |
| Ritenbaugh C et al. | Risk factors for Barrett's oesophagus: a life history approach to behavioural assessment in the distant past. | 1995 | Eur. J. Cancer Prev. | pmid:8580781 |
| Boscá F et al. | Evaluation of ketoprofen (R,S and R/S) phototoxicity by a battery of in vitro assays. | 1995 | J. Photochem. Photobiol. B, Biol. | pmid:8583281 |
| Bondarenko LB et al. | [Effect of 1,25-dihydroxyvitamin D3 on 15-lipoxygenase activity]. | 1995 May-Jun | Vopr. Med. Khim. | pmid:8585174 |
| Fuhrmann H and Sallmann HP | Alpha-tocopherol and phospholipase A2 in liver and brain of chicks posthatching: the influence of dietary fat and vitamin E. | 1995 | Ann. Nutr. Metab. | pmid:8585700 |
| Chawla A et al. | Effect of N-3 polyunsaturated fatty acid supplemented diet on neutrophil-mediated ileal permeability and neutrophil function in the rat. | 1995 | J Am Coll Nutr | pmid:8586775 |
| Périchon R and Bourre JM | Peroxisomal beta-oxidation activity and catalase activity during development and aging in mouse liver. | 1995 | Biochimie | pmid:8589059 |
| Rothacker DQ and Ellis PK | Linoleic acid supplementation in slimming products is unnecessary and may pose a potential added health risk to the user population. | 1995 | Int. J. Obes. Relat. Metab. Disord. | pmid:8589772 |
| Guil JL et al. | Identification of fatty acids in edible wild plants by gas chromatography. | 1996 | J Chromatogr A | pmid:8589832 |
| Aveldaño MI and Donnari D | Plasma phospholipid fatty acids in X-linked adrenoleukodystrophy. | 1996 | Clin. Chem. | pmid:8598113 |
| Babenko NA and Kavok NS | [The effect of thyroid hormones, phorbol esters, and sphingosine on incorporation of linoleic acid in liver lipids of white rats]. | 1995 | Biokhimiia | pmid:8600996 |
| Hennig B et al. | Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells. | 1996 | Am. J. Clin. Nutr. | pmid:8602587 |
| Routi T et al. | Effects of prospective, randomized cholesterol-lowering dietary intervention and apolipoprotein E phenotype on serum lipoprotein(a) concentrations of infants aged 7-24 mo. | 1996 | Am. J. Clin. Nutr. | pmid:8602597 |
| Ogretmen B et al. | Effects of sodium saccharin and linoleic acid on mRNA levels of Her2/neu and p53 in a human breast epithelial cell line. | 1996 | Cancer Lett. | pmid:8603385 |
| Liew C et al. | Protection of conjugated linoleic acids against 2-amino-3- methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms. | 1995 | Carcinogenesis | pmid:8603482 |
| Iwase H et al. | Superoxide anion reduces the ability of myeloperoxidase to damage lipids. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605038 |
| Yiin SJ and Lin TH | Lead-catalyzed peroxidation of essential unsaturated fatty acid. | 1995 | Biol Trace Elem Res | pmid:8605084 |
| Liu XH et al. | Eicosanoids as mediators of linoleic acid-stimulated invasion and type IV collagenase production by a metastatic human breast cancer cell line. | 1996 | Clin. Exp. Metastasis | pmid:8605728 |
| Ip C et al. | Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention. | 1995 | Nutr Cancer | pmid:8610043 |
| Louheranta AM et al. | Linoleic acid intake and susceptibility of very-low-density and low density lipoproteins to oxidation in men. | 1996 | Am. J. Clin. Nutr. | pmid:8615351 |
| van Egmond AW et al. | Effect of linoleic acid intake on growth of infants with cystic fibrosis. | 1996 | Am. J. Clin. Nutr. | pmid:8615359 |
| DeMar JC et al. | Biosynthesis of the unsaturated 14-carbon fatty acids found on the N termini of photoreceptor-specific proteins. | 1996 | J. Biol. Chem. | pmid:8617777 |
| Sidransky H and Verney E | Toxic effect of valproic acid on tryptophan binding to rat hepatic nuclei. | 1996 | Toxicology | pmid:8619251 |
| De Luca C et al. | Lipoperoxidase activity of Pityrosporum: characterisation of by-products and possible rôle in pityriasis versicolor. | 1996 | Exp. Dermatol. | pmid:8624612 |
| Iwase H et al. | Monoepoxide production from linoleic acid by cytochrome c in the presence of cardiolipin. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8630079 |
| Hussey HJ et al. | Novel anti-tumour activity of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4- benzoquinone (CV-6504) against established murine adenocarcinomas (MAC). | 1996 | Br. J. Cancer | pmid:8630277 |
| Reddy SR and Kotchen TA | Attenuation of experimental hypertension by dietary linoleic acid is model dependent. | 1996 | J Am Coll Nutr | pmid:8632122 |
| Márquez-Ruiz G and Dobarganes MC | Assessments on the digestibility of oxidized compounds from [1-14C] linoleic acid using a combination of chromatographic techniques. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8634750 |
| Hudson JA et al. | Factors affecting the formation of 10-hydroxystearic acid from oleic acid by a ruminal strain of Enterococcus faecalis. | 1996 | Appl. Microbiol. Biotechnol. | pmid:8639306 |
| Ip C et al. | The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet. | 1996 | Carcinogenesis | pmid:8640911 |
| Fischer SM et al. | Arachidonate has protumor-promoting action that is inhibited by linoleate in mouse skin carcinogenesis. | 1996 | J. Nutr. | pmid:8642440 |
| Ramasamy S et al. | Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells. | 1996 | Atherosclerosis | pmid:8645361 |
| Cleland LG et al. | Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. | 1996 | J. Nutr. | pmid:8648425 |
| Osada K et al. | Dietary protein modifies oxidized cholesterol-induced alterations of linoleic acid and cholesterol metabolism in rats. | 1996 | J. Nutr. | pmid:8648438 |
| Jensen CL et al. | Biochemical effects of dietary linoleic/alpha-linolenic acid ratio in term infants. | 1996 | Lipids | pmid:8649227 |
| Watkins BA et al. | Linoleate impairs collagen synthesis in primary cultures of avian chondrocytes. | 1996 | Proc. Soc. Exp. Biol. Med. | pmid:8650253 |
| Süttmann U et al. | Weight gain and increased concentrations of receptor proteins for tumor necrosis factor after patients with symptomatic HIV infection received fortified nutrition support. | 1996 | J Am Diet Assoc | pmid:8655902 |
| Loftin CD and Eling TE | Prostaglandin synthase 2 expression in epidermal growth factor-dependent proliferation of mouse keratinocytes. | 1996 | Arch. Biochem. Biophys. | pmid:8660674 |
| Watanabe N and Yamada S | Activation of 20S proteasomes from spinach leaves by fatty acids. | 1996 | Plant Cell Physiol. | pmid:8665092 |
| Murai A et al. | Involvement of (n-6) essential fatty acids and prostaglandins in liver lipid accumulation in Japanese quail. | 1996 | Am. J. Vet. Res. | pmid:8669766 |
| Akeo K et al. | Comparative effects of linoleic acid and linoleic acid hydroperoxide on growth and morphology of bovine retinal pigment epithelial cells in vitro. | 1996 | Curr. Eye Res. | pmid:8670748 |
| Chen ZY et al. | Accumulation of polyunsaturates is decreased by weight-cycling: whole-body analysis in young, growing rats. | 1996 | Br. J. Nutr. | pmid:8672410 |
| Ghafoorunissa | Nutrition & health implications of palm oil in Indian diets. | 1995 | Indian J. Med. Res. | pmid:8675244 |
| van Greevenbroek MM et al. | Effects of saturated, mono-, and polyunsaturated fatty acids on the secretion of apo B containing lipoproteins by Caco-2 cells. | 1996 | Atherosclerosis | pmid:8678919 |
| Jones GD et al. | Role of lipid hydroperoxides in the activation of 15-lipoxygenase. | 1996 | Biochemistry | pmid:8679548 |
| Rodakiewicz-Nowak J et al. | The effect of linoleic acid on pH inside sodium bis(2-ethylhexyl)sulfosuccinate reverse micelles in isooctane and on the enzymic activity of soybean lipoxygenase. | 1996 | Eur. J. Biochem. | pmid:8681970 |
| Carnielli VP et al. | Medium-chain triacylglycerols in formulas for preterm infants: effect on plasma lipids, circulating concentrations of medium-chain fatty acids, and essential fatty acids. | 1996 | Am. J. Clin. Nutr. | pmid:8694014 |
| Innis SM and Hansen JW | Plasma fatty acid responses, metabolic effects, and safety of microalgal and fungal oils rich in arachidonic and docosahexaenoic acids in healthy adults. | 1996 | Am. J. Clin. Nutr. | pmid:8694015 |
| Haraguchi H et al. | Inhibition of lipid peroxidation by diterpenoid from Podocarpus nagi. | 1996 | Experientia | pmid:8698092 |
| Surette ME et al. | Relationship between arachidonate--phospholipid remodeling and apoptosis. | 1996 | Biochemistry | pmid:8703924 |
| Ritskes-Hoitinga J et al. | Effects of two dietary fat levels and four dietary linoleic acid levels on mammary tumor development in Balb/c-MMTV mice under ad libitum feeding conditions. | 1996 | Nutr Cancer | pmid:8710685 |
| Akeo K et al. | Effects of superoxide dismutase and catalase on growth of retinal pigment epithelial cells in vitro following addition of linoleic acid or linoleic acid hydroperoxide. | 1996 | Ophthalmic Res. | pmid:8726672 |
| Kuroe K et al. | Pericholangitis in a rabbit colitis model induced by injection of muramyl dipeptide emulsified with a long-chain fatty acid. | 1996 | J. Gastroenterol. | pmid:8726825 |
| Pawlosky RJ et al. | Essential fatty acid uptake and metabolism in the developing rodent brain. | 1996 | Lipids | pmid:8729103 |
| Ziboh VA | The significance of polyunsaturated fatty acids in cutaneous biology. | 1996 | Lipids | pmid:8729128 |
| Griffin ME et al. | Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function. | 1996 | QJM | pmid:8731565 |
| Chaloner C et al. | Effect of oral supplementation with micronutrient antioxidants on trans fatty acid content of lipoproteins in healthy humans. | 1996 | Biochem. Soc. Trans. | pmid:8736849 |
| Campbell FM and Dutta-Roy AK | Asymmetric distribution of the plasma membrane fatty acid-binding protein (FABPpm) in the human placenta. | 1996 | Biochem. Soc. Trans. | pmid:8736907 |
| Bordoni A et al. | Metabolism of linoleic and alpha-linolenic acids in cultured cardiomyocytes: effect of different N-6 and N-3 fatty acid supplementation. | 1996 Apr 12-26 | Mol. Cell. Biochem. | pmid:8739249 |
| Fukushima M et al. | Comparative hypocholesterolemic effects of six vegetable oils in cholesterol-fed rat. | 1996 | Lipids | pmid:8743054 |
| Jenkins TC et al. | Butylsoyamide increases unsaturation of fatty acids in plasma and milk of lactating dairy cows. | 1996 | J. Dairy Sci. | pmid:8744223 |
| Murai A et al. | Role of dietary gamma-linolenic acid in liver lipid metabolism in Japanese quail. | 1995 | Br. Poult. Sci. | pmid:8746984 |
| Lin H et al. | Survey of the conjugated linoleic acid contents of dairy products. | 1995 | J. Dairy Sci. | pmid:8747326 |
| Cunnane SC and Yang J | Zinc deficiency impairs whole-body accumulation of polyunsaturates and increases the utilization of [1-14C]linoleate for de novo lipid synthesis in pregnant rats. | 1995 | Can. J. Physiol. Pharmacol. | pmid:8748973 |
| Fuhrmann H and Sallmann HP | The influence of dietary fatty acids and vitamin E on plasma prostanoids and liver microsomal alkane production in broiler chickens with regard to nutritional encephalomalacia. | 1995 | J. Nutr. Sci. Vitaminol. | pmid:8750206 |
| Earashi M et al. | In vitro effects of eicosanoid synthesis inhibitors in the presence of linoleic acid on MDA-MB-231 human breast cancer cells. | 1996 | Breast Cancer Res. Treat. | pmid:8750525 |
| Dunham WR et al. | Oleic acid and linoleic acid are the major determinants of changes in keratinocyte plasma membrane viscosity. | 1996 | J. Invest. Dermatol. | pmid:8751966 |
| Moghaddam M et al. | Novel metabolic pathways for linoleic and arachidonic acid metabolism. | 1996 | Biochim. Biophys. Acta | pmid:8765137 |
| Hrboticky N et al. | Linoleic acid esterified in low density lipoprotein serves as substrate for increased arachidonic acid synthesis in differentiating monocytic cells. | 1996 | Biochim. Biophys. Acta | pmid:8765140 |
| Wiesner R et al. | Nitric oxide oxidises a ferrous mammalian lipoxygenase to a pre-activated ferric species. | 1996 | FEBS Lett. | pmid:8766705 |
| Rosenquist A and Hølmer G | Nutritional value of micro-encapsulated fish oils in rats. | 1996 | Z Ernahrungswiss | pmid:8766891 |
| Takeuchi T | Essential fatty acid requirements in carp. | 1996 | Arch Tierernahr | pmid:8766970 |