Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sundrarjun T et al. | Effects of n-3 fatty acids on serum interleukin-6, tumour necrosis factor-alpha and soluble tumour necrosis factor receptor p55 in active rheumatoid arthritis. | 2004 Sep-Oct | J. Int. Med. Res. | pmid:15458276 |
| Derian CK and Lewis DF | Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1546066 |
| Javadi M et al. | The effect of six different C18 fatty acids on body fat and energy metabolism in mice. | 2004 | Br. J. Nutr. | pmid:15469642 |
| Houston M et al. | Oxidized linoleic acid regulates expression and shedding of syndecan-4. | 2005 | Am. J. Physiol., Cell Physiol. | pmid:15469957 |
| Ghosh S et al. | Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death. | 2004 | Nutrition | pmid:15474882 |
| Jaburek M et al. | Hydroperoxy fatty acid cycling mediated by mitochondrial uncoupling protein UCP2. | 2004 | J. Biol. Chem. | pmid:15475368 |
| Dullaart RP et al. | Long-term effects of linoleic-acid-enriched diet on albuminuria and lipid levels in type 1 (insulin-dependent) diabetic patients with elevated urinary albumin excretion. | 1992 | Diabetologia | pmid:1547922 |
| Piperova LS et al. | Changes in milk fat in response to dietary supplementation with calcium salts of trans-18:1 or conjugated linoleic fatty acids in lactating dairy cows. | 2004 | J. Dairy Sci. | pmid:15483168 |
| Hargrave KM et al. | Influence of dietary conjugated linoleic Acid and fat source on body fat and apoptosis in mice. | 2004 | Obes. Res. | pmid:15483208 |
| Valero M and Esteban B | Effect of binary and ternary polyvinylpyrrolidone and/or hydroxypropyl-beta-cyclodextrin complexes on the photochemical and photosensitizing properties of Naproxen. | 2004 | J. Photochem. Photobiol. B, Biol. | pmid:15488720 |
| Downie MM et al. | Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro. | 2004 | Br. J. Dermatol. | pmid:15491415 |
| Freeman VL et al. | Inverse association between prostatic polyunsaturated fatty acid and risk of locally advanced prostate carcinoma. | 2004 | Cancer | pmid:15495177 |
| Connolly JM and Rose DP | Interactions between epidermal growth factor-mediated autocrine regulation and linoleic acid-stimulated growth of a human prostate cancer cell line. | 1992 | Prostate | pmid:1549552 |
| Nilsson E and Bengtsson G | Endogenous free fatty acids repel and attract Collembola. | 2004 | J. Chem. Ecol. | pmid:15503529 |
| Baylin A and Campos H | Arachidonic acid in adipose tissue is associated with nonfatal acute myocardial infarction in the central valley of Costa Rica. | 2004 | J. Nutr. | pmid:15514281 |
| Mori TA et al. | Differential effect of aspirin on platelet aggregation in IDDM. | 1992 | Diabetes | pmid:1551486 |
| Egashira Y et al. | Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression. | 2004 | Biochim. Biophys. Acta | pmid:15522828 |
| Elmes M et al. | The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. | 2004 | Biochim. Biophys. Acta | pmid:15522830 |
| Adamska E et al. | Multivariate approach to evaluating the fatty acid composition of seed oil in a doubled haploid population of winter oilseed rape (Brassica napus L.). | 2004 | J. Appl. Genet. | pmid:15523152 |
| Homa ST and Brown CA | Changes in linoleic acid during follicular development and inhibition of spontaneous breakdown of germinal vesicles in cumulus-free bovine oocytes. | 1992 | J. Reprod. Fertil. | pmid:1552477 |
| Buang Y et al. | Alleviation of fatty liver by alpha-linolenic acid. | 2004 | J. Nutr. Sci. Vitaminol. | pmid:15527069 |
| Rinker KD et al. | Linoleic acid increases monocyte deformation and adhesion to endothelium. | 2004 | Atherosclerosis | pmid:15530900 |
| Jarmuszkiewicz W et al. | Redox state of endogenous coenzyme q modulates the inhibition of linoleic acid-induced uncoupling by guanosine triphosphate in isolated skeletal muscle mitochondria. | 2004 | J. Bioenerg. Biomembr. | pmid:15534396 |
| Miolo G et al. | Photochemistry and phototoxicity of fluocinolone 16,17-acetonide. | 2005 Mar-Apr | Photochem. Photobiol. | pmid:15535735 |
| Scholljegerdes EJ et al. | Influence of supplemental cracked high-linoleate or high-oleate safflower seeds on site and extent of digestion in beef cattle. | 2004 | J. Anim. Sci. | pmid:15537779 |
| Encinias HB et al. | High linoleic acid safflower seed supplementation for gestating ewes: effects on ewe performance, lamb survival, and brown fat stores. | 2004 | J. Anim. Sci. | pmid:15537787 |
| Huang HY et al. | Antioxidant activities of various fruits and vegetables produced in Taiwan. | 2004 | Int J Food Sci Nutr | pmid:15545051 |
| Chang PK et al. | Deletion of the Delta12-oleic acid desaturase gene of a nonaflatoxigenic Aspergillus parasiticus field isolate affects conidiation and sclerotial development. | 2004 | J. Appl. Microbiol. | pmid:15546408 |
| Duffield-Lillico AJ et al. | Can selenium prevent colorectal cancer? A signpost from epidemiology. | 2004 | J. Natl. Cancer Inst. | pmid:15547171 |
| Doderer A et al. | Purification and characterization of two lipoxygenase isoenzymes from germinating barley. | 1992 | Biochim. Biophys. Acta | pmid:1554746 |
| Marongiu B et al. | Antioxidant activity of supercritical extract of Melissa officinalis subsp. officinalis and Melissa officinalis subsp. inodora. | 2004 | Phytother Res | pmid:15551397 |
| Grichenko OE et al. | [Analysis of 15-lipoxygenase activity in irradiated thymocytes]. | 2004 Sep-Oct | Izv. Akad. Nauk. Ser. Biol. | pmid:15559127 |
| Boeckaert C et al. | Micro-algae as potent rumen methane inhibitors and modifiers of rumen lipolysis and biohydrogenation of linoleic acid. | 2004 | Commun. Agric. Appl. Biol. Sci. | pmid:15560204 |
| Yamamoto S et al. | The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals. | 2005 | Neuroscience | pmid:15561436 |
| Ahn MR et al. | Antioxidant activity and constituents of propolis collected in various areas of Korea. | 2004 | J. Agric. Food Chem. | pmid:15563208 |
| Cury-Boaventura MF and Curi R | Regulation of reactive oxygen species (ROS) production by C18 fatty acids in Jurkat and Raji cells. | 2005 | Clin. Sci. | pmid:15563273 |
| Wen X et al. | Antioxidative activity of a zinc-chelating substance in coffee. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15564670 |
| Diboune M et al. | Composition of phospholipid fatty acids in red blood cell membranes of patients in intensive care units: effects of different intakes of soybean oil, medium-chain triglycerides, and black-currant seed oil. | 1992 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:1556808 |
| Ringseis R et al. | Dietary conjugated linoleic acids lower the triacylglycerol concentration in the milk of lactating rats and impair the growth and increase the mortality of their suckling pups. | 2004 | J. Nutr. | pmid:15570033 |
| Whelan J and McEntee MF | Dietary (n-6) PUFA and intestinal tumorigenesis. | 2004 | J. Nutr. | pmid:15570048 |
| Hussein N et al. | Long-chain conversion of [13C]linoleic acid and alpha-linolenic acid in response to marked changes in their dietary intake in men. | 2005 | J. Lipid Res. | pmid:15576848 |
| Zhou B et al. | Antioxidative effects of flavonols and their glycosides against the free-radical-induced peroxidation of linoleic acid in solution and in micelles. | 2005 | Chemistry | pmid:15578643 |
| Bonanome A et al. | Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification. | 1992 | Arterioscler. Thromb. | pmid:1558840 |
| Zhou B et al. | Evidence for alpha-tocopherol regeneration reaction of green tea polyphenols in SDS micelles. | 2005 | Free Radic. Biol. Med. | pmid:15589374 |
| Javadi M et al. | Prolonged feeding of mice with conjugated linoleic acid increases hepatic fatty acid synthesis relative to oxidation. | 2004 | J. Nutr. Biochem. | pmid:15590272 |
| Burth P et al. | Role of nonesterified unsaturated fatty acids in the pathophysiological processes of leptospiral infection. | 2005 | J. Infect. Dis. | pmid:15593003 |
| Jiang Q et al. | gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15596715 |
| Wang YW et al. | Maternal dietary ratio of linoleic acid to alpha-linolenic acid affects the passive immunity of hatching chicks. | 2004 | Poult. Sci. | pmid:15615018 |
| Akai K et al. | Ability of ferric nitrilotriacetate complex with three pH-dependent conformations to induce lipid peroxidation. | 2004 | Free Radic. Res. | pmid:15621713 |
| Kris-Etherton PM et al. | Polyunsaturated fatty acids and cardiovascular health. | 2004 | Nutr. Rev. | pmid:15622714 |
| Edwards IJ et al. | Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. | 2004 | Clin. Cancer Res. | pmid:15623603 |
| Nagao K et al. | Dietary conjugated linoleic acid alleviates nonalcoholic fatty liver disease in Zucker (fa/fa) rats. | 2005 | J. Nutr. | pmid:15623825 |
| Ye P et al. | [An exploratory study on mechanism of PPARalpha activators-induced plasminogen activator inhibitor-1 expression in HepG-2 cells]. | 2004 | Zhonghua Nei Ke Za Zhi | pmid:15631825 |
| Wu MJ et al. | Antioxidant activity of Porcelainberry (Ampelopsis brevipedunculata (Maxim.) Trautv.). | 2004 | Am. J. Chin. Med. | pmid:15633804 |
| Lalush I et al. | Utilization of amylose-lipid complexes as molecular nanocapsules for conjugated linoleic Acid. | 2005 Jan-Feb | Biomacromolecules | pmid:15638512 |
| Mishra R and Simonson MS | Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G. | 2005 | Cardiovasc Diabetol | pmid:15642122 |
| Cheng Z et al. | The effect of a diet supplemented with the n-6 polyunsaturated fatty acid linoleic acid on prostaglandin production in early- and late-pregnant ewes. | 2005 | J. Endocrinol. | pmid:15642793 |
| Men: linoleic acid in your diet could ward off cancer. | 2004 | Health News | pmid:15645563 | |
| Nagai T et al. | Antioxidative ability in a linoleic acid oxidation system and scavenging abilities against active oxygen species of enzymatic hydrolysates from pollen Cistus ladaniferus. | 2005 | Int. J. Mol. Med. | pmid:15647841 |
| Mensink RP | Metabolic and health effects of isomeric fatty acids. | 2005 | Curr. Opin. Lipidol. | pmid:15650560 |
| Loor JJ et al. | Relationship among trans and conjugated fatty acids and bovine milk fat yield due to dietary concentrate and linseed oil. | 2005 | J. Dairy Sci. | pmid:15653539 |
| Schmidely P et al. | Influence of extruded soybeans with or without bicarbonate on milk performance and fatty acid composition of goat milk. | 2005 | J. Dairy Sci. | pmid:15653542 |
| Djoussé L et al. | Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study. | 2005 | Hypertension | pmid:15655119 |
| Zheng HF et al. | Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs. | 2005 | World J. Gastroenterol. | pmid:15655819 |
| Muangman P et al. | Antioxidants inhibit fatty acid and glucose-mediated induction of neutral endopeptidase gene expression in human microvascular endothelial cells. | 2005 | J. Am. Coll. Surg. | pmid:15664096 |
| Artemenko IP and Jefcoate CR | Multiple contributions from long-chain fatty acid metabolism in Y-1 and MA-10 cells. | 2004 | Endocr. Res. | pmid:15666804 |
| Laaksonen DE et al. | Prediction of cardiovascular mortality in middle-aged men by dietary and serum linoleic and polyunsaturated fatty acids. | 2005 | Arch. Intern. Med. | pmid:15668366 |
| Meyskens FL et al. | Diet and melanoma in a case-control study. | 2005 | Cancer Epidemiol. Biomarkers Prev. | pmid:15668513 |
| Attar-Bashi NM et al. | alpha-linolenic acid and the risk of prostate cancer. | 2004 | Lipids | pmid:15669769 |
| Brightman AO et al. | A growth factor- and hormone-stimulated NADH oxidase from rat liver plasma membrane. | 1992 | Biochim. Biophys. Acta | pmid:1567890 |
| Belkner J et al. | Expression of 12/15-lipoxygenase attenuates intracellular lipid deposition during in vitro foam cell formation. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15681297 |
| Taylor EN et al. | Fatty acid intake and incident nephrolithiasis. | 2005 | Am. J. Kidney Dis. | pmid:15685503 |
| Carrillo-DomÃnguez S et al. | Cholesterol and n-3 and n-6 fatty acid content in eggs from laying hens fed with red crab meal (Pleuroncodes planipes). | 2005 | Poult. Sci. | pmid:15685957 |
| Mendis E et al. | Antioxidant properties of a radical-scavenging peptide purified from enzymatically prepared fish skin gelatin hydrolysate. | 2005 | J. Agric. Food Chem. | pmid:15686405 |
| Xue HQ et al. | Aflatoxin production in peanut lines selected to represent a range of linoleic acid concentrations. | 2005 | J. Food Prot. | pmid:15690813 |
| Zock PL and Katan MB | Hydrogenation alternatives: effects of trans fatty acids and stearic acid versus linoleic acid on serum lipids and lipoproteins in humans. | 1992 | J. Lipid Res. | pmid:1569387 |
| Position of double bond of trans isomers of linoleic acid affects fatty acid desaturation and elongation. | 1992 | Nutr. Rev. | pmid:1570085 | |
| Cantwell MM et al. | Development and validation of a food-frequency questionnaire for the determination of detailed fatty acid intakes. | 2005 | Public Health Nutr | pmid:15705250 |
| Daoud G et al. | Expression of cFABP and PPAR in trophoblast cells: effect of PPAR ligands on linoleic acid uptake and differentiation. | 2005 | Biochim. Biophys. Acta | pmid:15708366 |
| Wang Y et al. | [Determination of vitamin E in linoleic acid-vitamin E soft capsules by gas chromatography]. | 2004 | Se Pu | pmid:15709439 |
| Yaguchi T et al. | Effects of cis-unsaturated free fatty acids on PKC-epsilon activation and nicotinic ACh receptor responses. | 2005 | Brain Res. Mol. Brain Res. | pmid:15710250 |
| Pakdeechanuan P et al. | Effects of rhodium heterogeneous catalyst and isomerization conditions on linoleic acid conjugation of soybean oil. | 2005 | J. Agric. Food Chem. | pmid:15712999 |
| MacKenzie SE et al. | Isolation of sterols from the marine fungus Corollospora lacera. | 2004 | Can. J. Microbiol. | pmid:15714238 |
| Lane ME et al. | Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model. | 2005 | J. Pharm. Pharmacol. | pmid:15720779 |
| Kelavkar UP et al. | Overexpression of 12/15-lipoxygenase, an ortholog of human 15-lipoxygenase-1, in the prostate tumors of TRAMP mice. | 2004 Nov-Dec | Neoplasia | pmid:15720809 |
| Kapich AN et al. | A rapid method to quantify pro-oxidant activity in cultures of wood-decaying white-rot fungi. | 2005 | J. Microbiol. Methods | pmid:15722153 |
| Banni S et al. | Conjugated linoleic acids (CLA) as precursors of a distinct family of PUFA. | 2004 | Lipids | pmid:15726830 |
| Nguyen LQ et al. | Intake of essential fatty acids by growing-finishing pigs kept on smallholdings in central Vietnam. | 2005 | Trop Anim Health Prod | pmid:15729898 |
| Thanasak J et al. | Effects of polyunsaturated fatty acids on the proliferation of mitogen stimulated bovine peripheral blood mononuclear cells. | 2005 | Vet. Immunol. Immunopathol. | pmid:15734550 |
| Lock AL and Bauman DE | Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health. | 2004 | Lipids | pmid:15736916 |
| Hibbeln JR et al. | Increasing homicide rates and linoleic acid consumption among five Western countries, 1961-2000. | 2004 | Lipids | pmid:15736917 |
| Lee SH et al. | Analysis of FeII-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry. | 2005 | J Mass Spectrom | pmid:15739161 |
| Delgado-Andrade C and Morales FJ | Unraveling the contribution of melanoidins to the antioxidant activity of coffee brews. | 2005 | J. Agric. Food Chem. | pmid:15740014 |
| Salas JJ et al. | Impact of the suppression of lipoxygenase and hydroperoxide lyase on the quality of the green odor in green leaves. | 2005 | J. Agric. Food Chem. | pmid:15740054 |
| Mitmesser SH and Carr TP | Trans fatty acids alter the lipid composition and size of apoB-100-containing lipoproteins secreted by HepG2 cells. | 2005 | J. Nutr. Biochem. | pmid:15741053 |
| Gülçin I et al. | Determination of in vitro antioxidant and radical scavenging activities of propofol. | 2005 | Chem. Pharm. Bull. | pmid:15744098 |
| Araseki M et al. | Lipid peroxidation of a human hepatoma cell line (HepG2) after incorporation of linoleic acid, arachidonic acid, and docosahexaenoic acid. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15784975 |
| Kannan R et al. | Anorexic contribution to increased linoleate mobilization and oxidation in lymphoma-bearing mice. | 1992 | Lipids | pmid:1579055 |
| Montalti D et al. | The chemical composition of the uropygial gland secretion of rock dove Columba livia. | 2005 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:15792592 |
| Cury-Boaventura MF et al. | Comparative toxicity of oleic acid and linoleic acid on Raji cells. | 2005 | Nutrition | pmid:15797684 |