Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Retinoblastoma D012175 12 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Keloid D007627 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Acidosis D000138 13 associated lipids
Critical Illness D016638 13 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Glucose Intolerance D018149 13 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Alopecia D000505 14 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Tremor D014202 15 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
pmid:26344318
Mizuta K et al. Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:26342087
pmid:26337666
Yen HW et al. Cultivation of oleaginous Rhodotorula mucilaginosa in airlift bioreactor by using seawater. 2016 J. Biosci. Bioeng. pmid:26319611
pmid:26318151
Lands B Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions. 2015 Biomed Res Int pmid:26301244
Buko VU et al. [Changes in the fatty acid composition of erythrocyte membranes in patients with chronic alcoholism under the effect of a diet enriched with linoleic acid]. 1989 Nov-Dec Vopr Pitan pmid:2629246
pmid:26286610
He J et al. Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. 2015 Yeast pmid:26284451
pmid:26280928
pmid:26277770
Kamano K et al. Effects of a high-linoleate and a high-alpha-linolenate diet on spontaneous mammary tumourigenesis in mice. 1989 Nov-Dec Anticancer Res. pmid:2627137
pmid:26265530
pmid:26249647
Valenzuela R et al. Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. 2015 Nutrients pmid:26247968
Beam J et al. Excess Linoleic Acid Increases Collagen I/III Ratio and "Stiffens" the Heart Muscle Following High Fat Diets. 2015 J. Biol. Chem. pmid:26240151
pmid:26239950
Fala AM et al. Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α. 2015 Sci Rep pmid:26237540
pmid:26235890
Tucker RM et al. No Difference in Perceived Intensity of Linoleic Acid in the Oral Cavity between Obese and Nonobese Individuals. 2015 Chem. Senses pmid:26232811
Evans SJ et al. Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales. 2015 J Psychiatr Res pmid:26228402
pmid:26207873
Lee CW et al. Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin. 2015 Biochem. Biophys. Res. Commun. pmid:26206084
Min JS et al. Monitoring the formation of cholesterol oxidation products in model systems using response surface methodology. 2015 Lipids Health Dis pmid:26201850
Farvid MS et al. Response to Letters Regarding Article, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". 2015 Circulation pmid:26195494
Lucas M Letter by Lucas Regarding Articles, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies" and "Circulating Omega-6 Polyunsaturated Fatty Acids and Total and Cause-Specific Mortality: The Cardiovascular Health Study". 2015 Circulation pmid:26195492
Hoenselaar R Letter by Hoenselaar Regarding Article, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". 2015 Circulation pmid:26195491
Yuan T et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. 2015 Int J Clin Exp Pathol pmid:26191198
pmid:26189725
pmid:26187936
Marinho GS et al. Lipids and Composition of Fatty Acids of Saccharina latissima Cultivated Year-Round in Integrated Multi-Trophic Aquaculture. 2015 Mar Drugs pmid:26184241
Baylin A et al. Serum Trans Fatty Acids Are Not Associated with Weight Gain or Linear Growth in School-Age Children. 2015 J. Nutr. pmid:26180252
pmid:26174350
pmid:26169870
pmid:26162796
pmid:26151719
pmid:26142845
Salehi R et al. A prepartum diet supplemented with oilseeds high in oleic or linoleic acid reduced GnRH-induced LH release in dairy cows during second week postpartum. 2015 Reprod. Biol. Endocrinol. pmid:26138920
Grevengoed TJ et al. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. 2015 J. Lipid Res. pmid:26136511
Park JH et al. Effects of dietary linoleic acid on mucosal adaptation after small bowel resection. 1989 Digestion pmid:2612750
Hasiewicz-Derkacz K et al. Natural phenolics greatly increase flax (Linum usitatissimum) oil stability. 2015 BMC Biotechnol. pmid:26123633
Naughton SS et al. Australia's nutrition transition 1961-2009: a focus on fats. 2015 Br. J. Nutr. pmid:26123446
Fairbank J et al. Octadeca-9,11-dienoic acid in cervical intraepithelial neoplasia: a colposcopic study. 1989 Clin. Chim. Acta pmid:2612010
Rosero DS et al. Impact of dietary lipids on sow milk composition and balance of essential fatty acids during lactation in prolific sows. 2015 J. Anim. Sci. pmid:26115280
pmid:26094213
pmid:26079999
Alsaidan M et al. Cells to Surgery Quiz: July 2015. 2015 J. Invest. Dermatol. pmid:26066894
pmid:26054662
pmid:26051603
pmid:26043928
pmid:26041199
Pruzanski W et al. Diverse activity of human secretory phospholipases A2 on the migration of human vascular smooth muscle cells. 2015 Inflamm. Res. pmid:25999087
pmid:25997576
pmid:25987423
Zeb A and Ullah S Sea buckthorn seed oil protects against the oxidative stress produced by thermally oxidized lipids. 2015 Food Chem pmid:25976784
Clouet P et al. Pathway of alpha-linolenic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids. 1989 Biochem. J. pmid:2597132
Schumann T et al. Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment. 2015 Oncotarget pmid:25968567
Hirata A et al. A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus. 2015 J. Lipid Res. pmid:25966711
Shivashankar S and Sumathi M Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? 2015 J. Biosci. pmid:25963264
pmid:25952888
Turci F et al. Free-radical chemistry as a means to evaluate lunar dust health hazard in view of future missions to the moon. 2015 Astrobiology pmid:25946080
Perumalsamy H et al. Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. 2015 Parasit Vectors pmid:25928224
Chanussot B et al. Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats. 1989 Diabetologia pmid:2591647
pmid:25916258
pmid:25906856
Dahlhoff M et al. EGFR/ERBB receptors differentially modulate sebaceous lipogenesis. 2015 FEBS Lett. pmid:25889637
pmid:25888677
pmid:25877046
pmid:25876988
Gouveia-Figueira S et al. Serum levels of oxylipins in achilles tendinopathy: an exploratory study. 2015 PLoS ONE pmid:25875933
pmid:25874840
Hiramatsu N et al. Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate. 1989 J. Nutr. Sci. Vitaminol. pmid:2585150
pmid:25843422
Yao X et al. Effects of thyroid hormone status on metabolic pathways of arachidonic acid in mice and humans: A targeted metabolomic approach. Prostaglandins Other Lipid Mediat. pmid:25841349
Diehl AK et al. Dietary intake and the prevalence of gallbladder disease in Mexican Americans. 1989 Gastroenterology pmid:2583417
Mansour AB et al. Effect of agricultural sites on differentiation between Chemlali and Neb Jmel olive oils. 2015 J Oleo Sci pmid:25833451
pmid:25828430
Stoeck M et al. Studies on the mechanism whereby cyclosporin A inhibits T-lymphocyte activation. 1985 Immunobiology pmid:2580777
Alnaseri H et al. Inducible Expression of a Resistance-Nodulation-Division-Type Efflux Pump in Staphylococcus aureus Provides Resistance to Linoleic and Arachidonic Acids. 2015 J. Bacteriol. pmid:25802299
Chen S et al. Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. 2015 PLoS ONE pmid:25799542
Manosalva C et al. Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. 2015 PLoS ONE pmid:25790461
Xing J et al. Determining antioxidant activities of lactobacilli cell-free supernatants by cellular antioxidant assay: a comparison with traditional methods. 2015 PLoS ONE pmid:25789875
pmid:25787691
Saccenti E et al. Strategies for individual phenotyping of linoleic and arachidonic acid metabolism using an oral glucose tolerance test. 2015 PLoS ONE pmid:25786212
Negrini R et al. pH-responsive lyotropic liquid crystals and their potential therapeutic role in cancer treatment. 2015 Chem. Commun. (Camb.) pmid:25783035
pmid:25781458
Bourre JM et al. Composition of nerve biomembranes and nutritional fatty acids. 1989 Jul-Aug Nutrition pmid:2577681
pmid:25771044
pmid:25770319
Fujiyama-Fujiwara Y et al. Metabolism of gamma-linolenic acid in primary cultures of rat hepatocytes and in Hep G2 cells. 1989 J. Nutr. Sci. Vitaminol. pmid:2576804
Yoshida Y et al. Chemistry of lipid peroxidation products and their use as biomarkers in early detection of diseases. 2015 J Oleo Sci pmid:25766928
Ciepiela P et al. Arachidonic and linoleic acid derivatives impact oocyte ICSI fertilization--a prospective analysis of follicular fluid and a matched oocyte in a 'one follicle--one retrieved oocyte--one resulting embryo' investigational setting. 2015 PLoS ONE pmid:25763593
pmid:25760551
Bourre JM et al. The effects of dietary alpha-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. 1989 J. Nutr. pmid:2576038
Hernandez LR et al. Effect of plant growth regulators on fatty acids composition in Jatropha curcas L. callus culture. 2015 J Oleo Sci pmid:25757437
Kotani K et al. Enzymatic preparation of human milk fat substitutes and their oxidation stability. 2015 J Oleo Sci pmid:25757431
Hashim RB et al. Fatty acid compositions of silver catfish, Pangasius sp. farmed in several rivers of Pahang, Malaysia. 2015 J Oleo Sci pmid:25748380
Chang TS et al. Palm oil derived trimethylolpropane triesters synthetic lubricants and usage in industrial metalworking fluid. 2015 J Oleo Sci pmid:25748374
Tyurina YY et al. LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. 2015 Free Radic. Res. pmid:25740198
Wang S et al. Plasma nutrient biomarkers are associated with waist-to-height ratio in youth with type 1 diabetes. 2015 J. Nutr. pmid:25733475