Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Infant, Newborn, Diseases D007232 9 associated lipids
Infertility D007246 3 associated lipids
Infertility, Male D007248 11 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Keloid D007627 12 associated lipids
Darier Disease D007644 2 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Lactose Intolerance D007787 2 associated lipids
Leptospirosis D007922 2 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liposarcoma D008080 1 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Elias SL and Innis SM Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. 2001 Am. J. Clin. Nutr. pmid:11273857
Cunnane SC et al. Beta-oxidation of linoleate in obese men undergoing weight loss. 2001 Am. J. Clin. Nutr. pmid:11273844
Kumamoto M et al. Effects of pH and metal ions on antioxidative activities of catechins. 2001 Biosci. Biotechnol. Biochem. pmid:11272815
Precht D et al. Overestimates of oleic and linoleic acid contents in materials containing trans fatty acids and analyzed with short packed gas chromatographic columns. 2001 Lipids pmid:11269704
Chuang LT et al. Effect of conjugated linoleic acid on fungal delta6-desaturase activity in a transformed yeast system. 2001 Lipids pmid:11269694
Turnock L et al. Dietary supplementation with conjugated linoleic acid does not alter the resistance of mice to Listeria monocytogenes infection. 2001 Lipids pmid:11269693
Ponticelli F et al. Synthesis and antiperoxidant activity of new phenolic O-glycosides. 2001 Carbohydr. Res. pmid:11269397
Bassaganya-Riera J et al. Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence. 2001 J. Anim. Sci. pmid:11263832
Warner K et al. Effect of oleic and linoleic acids on the production of deep-fried odor in heated triolein and trilinolein. 2001 J. Agric. Food Chem. pmid:11262047
Xue Y et al. [Effects of conjugated linoleic acid on the metastasis of mouse melanoma B16-MB]. 2001 Wei Sheng Yan Jiu pmid:11255760
Higdon JV et al. Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate. 2001 J. Lipid Res. pmid:11254753
Korotkova M et al. Maternal essential fatty acid deficiency depresses serum leptin levels in suckling rat pups. 2001 J. Lipid Res. pmid:11254747
Michels KB et al. Dietary antioxidant vitamins, retinol, and breast cancer incidence in a cohort of Swedish women. 2001 Int. J. Cancer pmid:11251982
Loreau O et al. Sequential substitution of 1,2-dichloro-ethene: a convenient stereoselective route to (9Z,11E)-, (10E,12Z)- and (10Z,12Z)-. 2001 Chem. Phys. Lipids pmid:11245835
Boudreau MD et al. Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways. 2001 Cancer Res. pmid:11245439
Slim R et al. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. 2001 Toxicol. Appl. Pharmacol. pmid:11243918
George P et al. Phospholipids reacylation and palmitoylcoa control tumour necrosis factor-alpha sensitivity. 2001 Cytokine pmid:11243703
Gill HS and Cross ML Anticancer properties of bovine milk. 2000 Br. J. Nutr. pmid:11242461
Pfeuffer M and Schrezenmeir J Bioactive substances in milk with properties decreasing risk of cardiovascular diseases. 2000 Br. J. Nutr. pmid:11242460
Igarashi M and Miyazawa T The growth inhibitory effect of conjugated linoleic acid on a human hepatoma cell line, HepG2, is induced by a change in fatty acid metabolism, but not the facilitation of lipid peroxidation in the cells. 2001 Biochim. Biophys. Acta pmid:11239819
Aydin R et al. Olive oil prevents the adverse effects of dietary conjugated linoleic acid on chick hatchability and egg quality. 2001 J. Nutr. pmid:11238762
Hauville C et al. Radiation induced peroxidation of polyunsaturated fatty acids: recent results on formation of hydroperoxides. 2001 Can. J. Physiol. Pharmacol. pmid:11233566
Baer RJ et al. Composition and properties of milk and butter from cows fed fish oil. 2001 J. Dairy Sci. pmid:11233018
Du M et al. Volatile profiles and lipid oxidation of irradiated cooked chicken meat from laying hens fed diets containing conjugated linoleic acid. 2001 Poult. Sci. pmid:11233015
Sell JL et al. Metabolizable energy value of conjugated linoleic acid for broiler chicks and laying hens. 2001 Poult. Sci. pmid:11233010
Dandona P et al. The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. 2001 J. Clin. Endocrinol. Metab. pmid:11232024
Osman H et al. Fatty acids bind to the fungal elicitor cryptogein and compete with sterols. 2001 FEBS Lett. pmid:11231013
Ogawa J et al. Conjugated linoleic acid accumulation via 10-hydroxy-12-octadecaenoic acid during microaerobic transformation of linoleic acid by Lactobacillus acidophilus. 2001 Appl. Environ. Microbiol. pmid:11229917
Garcia JR et al. Macrophages transfer [14C]-labelled fatty acids to pancreatic islets in culture. 2001 Cell Biochem. Funct. pmid:11223866
Neri S et al. Association of alpha-interferon and acetyl cysteine in patients with chronic C hepatitis. 2000 Panminerva Med pmid:11218623
Higashi K et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. 2001 Lipids pmid:11214722
Cavicchioli P et al. Endogenous surfactant turnover in preterm infants with respiratory distress syndrome studied with stable isotope lipids. 2001 Am. J. Respir. Crit. Care Med. pmid:11208626
Lance VA et al. Hyperlipidemia and reproductive failure in captive-reared alligators: vitamin E, vitamin A, plasma lipids, fatty acids, and steroid hormones. 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11207442
Kajiwara T et al. Fatty acid oxidizing activity in a red marine alga, Porphyra sp. 2000 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:11204194
Jayaprakasha GK and Rao LJ Phenolic constituents from the lichen Parmotrema stuppeum (Nyl.) Hale and their antioxidant activity. 2000 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:11204179
Carvajal O et al. Effect of medium-chain fatty acid positional distribution in dietary triacylglycerol on lymphatic lipid transport and chylomicron composition in rats. 2000 Lipids pmid:11201996
Li Z et al. Hepatic microsomal and peroxisomal docosahexaenoate biosynthesis during piglet development. 2000 Lipids pmid:11201994
Brown JE et al. Linoleic acid metabolism in the spontaneously diabetic rat: delta6-desaturase activity vs. product/precursor ratios. 2000 Lipids pmid:11201993
Boscá F et al. Involvement of type I and type II mechanisms in the linoleic acid peroxidation photosensitized by tiaprofenic acid. 2000 J. Photochem. Photobiol. B, Biol. pmid:11195846
Du M et al. Effects of dietary conjugated linoleic acid and linoleic:linolenic acid ratio on polyunsaturated fatty acid status in laying hens. 2000 Poult. Sci. pmid:11194037
Cheon SH et al. Effect of dietary linoleate/alpha-linolenate balance on the brain lipid composition, reproductive outcome and behavior of rats during their prenatal and postnatal development. 2000 Biosci. Biotechnol. Biochem. pmid:11193394
Dyck DJ Dietary fat intake, supplements, and weight loss. 2000 Can J Appl Physiol pmid:11187927
Burczynski JM et al. Suppression of lipid peroxidation in adrenal microsomes following ACTH administration to guinea pigs. 2001 J. Endocrinol. pmid:11182771
Hughes RK et al. Mutagenesis and modelling of linoleate-binding to pea seed lipoxygenase. 2001 Eur. J. Biochem. pmid:11179969
Thomas Yeung CH et al. Dietary conjugated linoleic acid mixture affects the activity of intestinal acyl coenzyme A: cholesterol acyltransferase in hamsters. 2000 Br. J. Nutr. pmid:11177212
Cunnane SC The conditional nature of the dietary need for polyunsaturates: a proposal to reclassify 'essential fatty acids' as 'conditionally-indispensable' or 'conditionally-dispensable' fatty acids. 2000 Br. J. Nutr. pmid:11177196
Khosla P and Fungwe TV Conjugated linoleic acid: effects on plasma lipids and cardiovascular function. 2001 Curr. Opin. Lipidol. pmid:11176200
Whigham LD et al. CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheae. 2001 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11171673
Nuñez A et al. Anaerobic lipoxygenase activity from Chlorella pyrenoidosa. 2000 Biochem. Soc. Trans. pmid:11171268
Kaushik N and Vir S Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India. 2000 Biochem. Soc. Trans. pmid:11171243