Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Infant, Newborn, Diseases D007232 9 associated lipids
Infertility D007246 3 associated lipids
Infertility, Male D007248 11 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Keloid D007627 12 associated lipids
Darier Disease D007644 2 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Lactose Intolerance D007787 2 associated lipids
Leptospirosis D007922 2 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liposarcoma D008080 1 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Kashulin PA et al. Extremely rapid effects of polyunsaturated fatty acids and N-acetylglucosamine on free-radical metabolism in cultured potato plant cells. 2000 Biochem. Soc. Trans. pmid:11171236
Grechkin AN et al. Lipoxygenase pathway in tulip: biosynthesis of ketols. 2000 Biochem. Soc. Trans. pmid:11171230
Kamisaka Y and Noda N Intracellular transport of phosphatidic acid and phosphatidylcholine into lipid bodies: use of fluorescent lipids to study lipid-body formation in an oleaginous fungus. 2000 Biochem. Soc. Trans. pmid:11171185
Verwoert I et al. The molecular basis of the high linoleic acid content in Petunia seed oil: analysis of a seed-specific linoleic acid mutant. 2000 Biochem. Soc. Trans. pmid:11171150
Kaushik N and Agnihotri A GLC analysis of Indian rapeseed-mustard to study the variability of fatty acid composition. 2000 Biochem. Soc. Trans. pmid:11171132
López-Nicolás JM et al. Eggplant lipoxygenase (Solanum melongena): product characterization and effect of physicochemical properties of linoleic acid on the enzymatic activity. 2001 J. Agric. Food Chem. pmid:11170610
Rival SG et al. Caseins and casein hydrolysates. 2. Antioxidative properties and relevance to lipoxygenase inhibition. 2001 J. Agric. Food Chem. pmid:11170591
Widstrom RL et al. Binding of cytochrome P450 monooxygenase and lipoxygenase pathway products by heart fatty acid-binding protein. 2001 Biochemistry pmid:11170430
Ramírez-Expósito MJ et al. Oleate, linoleate and cholesterol differently modify aspartyl- and glutamyl-aminopeptidase activities in primary cultures of rat astrocytes. 2001 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:11166679
Dikalov SI and Mason RP Spin trapping of polyunsaturated fatty acid-derived peroxyl radicals: reassignment to alkoxyl radical adducts. 2001 Free Radic. Biol. Med. pmid:11163536
Soppela P and Nieminen M The effect of wintertime undernutrition on the fatty acid composition of leg bone marrow fats in reindeer (Rangifer tarandus tarandus L.). 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11163305
Sakuma S et al. The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11161586
Shureiqi I et al. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. 2000 Cancer Res. pmid:11156377
Scimeca JA and Miller GD Potential health benefits of conjugated linoleic acid. 2000 J Am Coll Nutr pmid:11153468
Kawai T et al. Chronic effects of different fatty acids and leptin in INS-1 cells. 2001 Diabetes Res. Clin. Pract. pmid:11137176
Kontush A et al. Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma. 2001 Free Radic. Biol. Med. pmid:11134902
Marín MC et al. Dietary long-chain fatty acids and visual response in malnourished nursing infants. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11133176
Masuda A et al. Study of lipid in the ear canal in canine otitis externa with Malassezia pachydermatis. 2000 J. Vet. Med. Sci. pmid:11129861
Yamasaki M et al. Dietary conjugated linoleic acid increases immunoglobulin productivity of Sprague-Dawley rat spleen lymphocytes. 2000 Biosci. Biotechnol. Biochem. pmid:11129589
Bemelmans WJ et al. Associations of alpha-linolenic acid and linoleic acid with risk factors for coronary heart disease. 2000 Eur J Clin Nutr pmid:11114683
Fitch CD et al. A role for linoleic acid in erythrocytes infected with Plasmodium berghei. 2000 Biochim. Biophys. Acta pmid:11113630
Innis SM The role of dietary n-6 and n-3 fatty acids in the developing brain. 2000 Sep-Dec Dev. Neurosci. pmid:11111165
Bee G Dietary conjugated linoleic acid consumption during pregnancy and lactation influences growth and tissue composition in weaned pigs. 2000 J. Nutr. pmid:11110857
Blankson H et al. Conjugated linoleic acid reduces body fat mass in overweight and obese humans. 2000 J. Nutr. pmid:11110851
Thuillier P et al. Activators of peroxisome proliferator-activated receptor-alpha partially inhibit mouse skin tumor promotion. 2000 Mol. Carcinog. pmid:11108658
Bauman DE et al. Technical note: production of butter with enhanced conjugated linoleic acid for use in biomedical studies with animal models. 2000 J. Dairy Sci. pmid:11104258
Ostrowska E et al. Comparison of silver-ion high-performance liquid chromatographic quantification of free and methylated conjugated linoleic acids. 2000 Lipids pmid:11104021
Kelley DS et al. Dietary conjugated linoleic acid did not alter immune status in young healthy women. 2000 Lipids pmid:11104011
Gardner HW et al. Biotransformation of linoleic acid by Clavibacter sp. ALA2: heterocyclic and heterobicyclic fatty acids. 2000 Lipids pmid:11104009
van Dijk K and Nelson EB Fatty acid competition as a mechanism by which Enterobacter cloacae suppresses Pythium ultimum sporangium germination and damping-off. 2000 Appl. Environ. Microbiol. pmid:11097912
Kim YJ et al. Effect of linoleic acid concentration on conjugated linoleic acid production by Butyrivibrio fibrisolvens A38. 2000 Appl. Environ. Microbiol. pmid:11097894
Minich DM et al. Intestinal absorption and postabsorptive metabolism of linoleic acid in rats with short-term bile duct ligation. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11093947
Kwok CF et al. Linoleic acid and oleic acid increase the endothelin-1 binding and action in cultured rat aortic smooth muscle cells. 2000 Metab. Clin. Exp. pmid:11092498
Ueno S et al. Polymorphism of linoleic acid (cis-9, cis-12-octadecadienoic acid) and alpha-linolenic acid (cis-9, cis-12, cis-15-octadecatrienoic acid). 2000 Chem. Phys. Lipids pmid:11090846
Mizushina Y et al. Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. 2000 J. Mol. Biol. pmid:11090281
Louw L Keloids in rural black South Africans. Part 3: a lipid model for the prevention and treatment of keloid formations. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090251
Louw L and Dannhauser A Keloids in rural black South Africans. Part 2: dietary fatty acid intake and total phospholipid fatty acid profile in the blood of keloid patients. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090250
Lehtinen P and Laakso S Inhibition of linoleic acid oxidation by interaction with a protein-rich oat fraction. 2000 J. Agric. Food Chem. pmid:11087534
Grechkin AN et al. The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route. 2000 Biochem. J. pmid:11085944
Hochi S et al. Nuclear transfer in cattle : effect of linoleic acid-albumin on freezing sensitivity of enucleated oocytes. 2000 J. Vet. Med. Sci. pmid:11073086
Cahoon EB et al. Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid. 2001 J. Biol. Chem. pmid:11067856
Lance A et al. 13C-linoleic acid oxidation and transfer into milk in lactating women with contrasting body mass index. 2000 Adv. Exp. Med. Biol. pmid:11065106
Del Prado M et al. Contribution of dietary and newly formed arachidonic acid to milk secretion in women on low fat diets. 2000 Adv. Exp. Med. Biol. pmid:11065105
Sauerwald TU et al. Polyunsaturated fatty acid supply with human milk. Physiological aspects and in vivo studies of metabolism. 2000 Adv. Exp. Med. Biol. pmid:11065079
Granot E et al. Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. 2000 Am. J. Clin. Nutr. pmid:11063450
Brynes AE et al. Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. 2000 Am. J. Clin. Nutr. pmid:11063437
French P et al. Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets. 2000 J. Anim. Sci. pmid:11063308
Ferry DR et al. A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. 2000 Ann. Oncol. pmid:11061613
Cunnane SC et al. Specific linoleate deficiency in the rat does not prevent substantial carbon recycling from [(14)C]linoleate into sterols. 2000 J. Lipid Res. pmid:11060350
Surai PF et al. Effect of long-term supplementation with arachidonic or docosahexaenoic acids on sperm production in the broiler chicken. 2000 J. Reprod. Fertil. pmid:11058441