Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Infant, Newborn, Diseases D007232 9 associated lipids
Infertility D007246 3 associated lipids
Infertility, Male D007248 11 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Keloid D007627 12 associated lipids
Darier Disease D007644 2 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Lactose Intolerance D007787 2 associated lipids
Leptospirosis D007922 2 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liposarcoma D008080 1 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Qian Z et al. Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. 2015 Sci Rep pmid:26615818
Fu X et al. Regulation of formation of volatile compounds of tea (Camellia sinensis) leaves by single light wavelength. 2015 Sci Rep pmid:26567525
Guyenet SJ and Carlson SE Increase in adipose tissue linoleic acid of US adults in the last half century. 2015 Adv Nutr pmid:26567191
Phan CW et al. Uridine from Pleurotus giganteus and Its Neurite Outgrowth Stimulatory Effects with Underlying Mechanism. 2015 PLoS ONE pmid:26565787
Rondanelli M et al. Effects of two-months balanced diet in metabolically healthy obesity: lipid correlations with gender and BMI-related differences. 2015 Lipids Health Dis pmid:26511930
Ellero-Simatos S et al. Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study. 2015 J Am Heart Assoc pmid:26504148
Ressurreição M et al. Sensory Protein Kinase Signaling in Schistosoma mansoni Cercariae: Host Location and Invasion. 2015 J. Infect. Dis. pmid:26401028
Delmastro-Greenwood M et al. Nitrite and nitrate-dependent generation of anti-inflammatory fatty acid nitroalkenes. 2015 Free Radic. Biol. Med. pmid:26385079
Grevengoed TJ et al. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. 2015 J. Lipid Res. pmid:26136511
Hasiewicz-Derkacz K et al. Natural phenolics greatly increase flax (Linum usitatissimum) oil stability. 2015 BMC Biotechnol. pmid:26123633
Rosero DS et al. Impact of dietary lipids on sow milk composition and balance of essential fatty acids during lactation in prolific sows. 2015 J. Anim. Sci. pmid:26115280
Shivashankar S and Sumathi M Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? 2015 J. Biosci. pmid:25963264
Alsaidan M et al. Cells to Surgery Quiz: July 2015. 2015 J. Invest. Dermatol. pmid:26066894
Schumann T et al. Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment. 2015 Oncotarget pmid:25968567
Hirata A et al. A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus. 2015 J. Lipid Res. pmid:25966711
Turci F et al. Free-radical chemistry as a means to evaluate lunar dust health hazard in view of future missions to the moon. 2015 Astrobiology pmid:25946080
Dahlhoff M et al. EGFR/ERBB receptors differentially modulate sebaceous lipogenesis. 2015 FEBS Lett. pmid:25889637
Gouveia-Figueira S et al. Serum levels of oxylipins in achilles tendinopathy: an exploratory study. 2015 PLoS ONE pmid:25875933
Mansour AB et al. Effect of agricultural sites on differentiation between Chemlali and Neb Jmel olive oils. 2015 J Oleo Sci pmid:25833451
Alnaseri H et al. Inducible Expression of a Resistance-Nodulation-Division-Type Efflux Pump in Staphylococcus aureus Provides Resistance to Linoleic and Arachidonic Acids. 2015 J. Bacteriol. pmid:25802299
Fajardo VA et al. Cardiolipin linoleic acid content and mitochondrial cytochrome c oxidase activity are associated in rat skeletal muscle. 2015 Chem. Phys. Lipids pmid:25727371
Chen S et al. Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. 2015 PLoS ONE pmid:25799542
Vlachogianni IC et al. In vitro assessment of antioxidant activity of tyrosol, resveratrol and their acetylated derivatives. 2015 Food Chem pmid:25660873
Askari M et al. Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. 2015 Clin Transl Oncol pmid:25351172
Chan BC et al. Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. 2015 J. Pharm. Pharmacol. pmid:25212982
Miyamoto J et al. A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. 2015 J. Biol. Chem. pmid:25505251
Liu H et al. Transient receptor potential vanilloid 1 gene deficiency ameliorates hepatic injury in a mouse model of chronic binge alcohol-induced alcoholic liver disease. 2015 Am. J. Pathol. pmid:25447051
Reinders I et al. Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults. 2015 J. Nutr. pmid:25355842
Perumalsamy H et al. Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. 2015 Parasit Vectors pmid:25928224
Nakahashi H et al. Evaluation of the Key Odorants in Volatile Oils from Tubers of Apios americana Medikus. 2015 J Oleo Sci pmid:26521814
Naughton SS et al. Australia's nutrition transition 1961-2009: a focus on fats. 2015 Br. J. Nutr. pmid:26123446
Yildiztekin F et al. Antioxidant, anticholinesterase and tyrosinase inhibition activities, and fatty acids of Crocus mathewii - A forgotten endemic angiosperm of Turkey. 2016 Pharm Biol pmid:26810584
Ma C et al. NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. 2016 Nature pmid:26934227
Padayachee T et al. The Detection of Metabolite-Mediated Gene Module Co-Expression Using Multivariate Linear Models. 2016 PLoS ONE pmid:26918614
Hellström F et al. Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain. 2016 BMC Musculoskelet Disord pmid:26916287
Ripoll-Rozada J et al. Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation. 2016 Mol. Microbiol. pmid:26915347
Harris WS et al. Red Blood Cell Fatty Acids and Incident Diabetes Mellitus in the Women's Health Initiative Memory Study. 2016 PLoS ONE pmid:26881936
DoÄŸru-Koca A et al. Chemotaxonomic perspectives of the Paracaryum (Cynoglosseae, Boraginaceae) taxa based on fruit fatty acid composition. 2016 Phytochemistry pmid:27600716
Troche JR et al. Alcohol Consumption-Related Metabolites in Relation to Colorectal Cancer and Adenoma: Two Case-Control Studies Using Serum Biomarkers. 2016 PLoS ONE pmid:26967509
Valdez-Morales M et al. Phenolic Compounds, Antioxidant Activity and Lipid Profile of Huitlacoche Mushroom (Ustilago maydis) Produced in Several Maize Genotypes at Different Stages of Development. 2016 Plant Foods Hum Nutr pmid:27605221
Shapiro H et al. Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27067460
Takabe W et al. Esterification of 24S-OHC induces formation of atypical lipid droplet-like structures, leading to neuronal cell death. 2016 J. Lipid Res. pmid:27647838
Zhang YH et al. The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life. 2016 PLoS ONE pmid:27780226
Rodrigues HG et al. Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats. 2016 PLoS ONE pmid:27764229
Kojima K et al. A simple method for isolation and construction of markerless cyanobacterial mutants defective in acyl-acyl carrier protein synthetase. 2016 Appl. Microbiol. Biotechnol. pmid:27704180
Ishida K and Jolly ER Hsp70 May Be a Molecular Regulator of Schistosome Host Invasion. 2016 PLoS Negl Trop Dis pmid:27611863
Venäläinen TM et al. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. 2016 Am. J. Clin. Nutr. pmid:27581473
Sakayori N et al. Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring's Anxious Behavior with a Sex-Dependent Manner in Mice. 2016 Tohoku J. Exp. Med. pmid:27558477
Bradley RM et al. Influence of tissue, diet, and enzymatic remodeling on cardiolipin fatty acyl profile. 2016 Mol Nutr Food Res pmid:27061349
Abdullah BM et al. Polyesters Based on Linoleic Acid for Biolubricant Basestocks: Low-Temperature, Tribological and Rheological Properties. 2016 PLoS ONE pmid:27008312