Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Infant, Newborn, Diseases D007232 9 associated lipids
Infertility D007246 3 associated lipids
Infertility, Male D007248 11 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Keloid D007627 12 associated lipids
Darier Disease D007644 2 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Lactose Intolerance D007787 2 associated lipids
Leptospirosis D007922 2 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liposarcoma D008080 1 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Nakagawa Y [Metabolism and biological function of cardiolipin]. 2013 Yakugaku Zasshi pmid:23649397
Otsuka H et al. [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. 1981 Yakugaku Zasshi pmid:7338798
Osaki Y et al. [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]. 1994 Yakugaku Zasshi pmid:8014843
Yamamoto K et al. [Antimutagenic substances in the Armeniacae semen and Persicae semen]. 1992 Yakugaku Zasshi pmid:1294719
Byczkowski JZ and Kulkarni AP Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. 1992 Xenobiotica pmid:1413876
Cardoso CR et al. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. 2004 Mar-Apr Wound Repair Regen pmid:15086775
Dubnov G and Berry EM Omega-6/omega-3 fatty acid ratio: the Israeli paradox. 2003 World Rev Nutr Diet pmid:14579685
Zampelas A et al. Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. 2003 World Rev Nutr Diet pmid:14579686
Hamazaki T and Okuyama H The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. 2003 World Rev Nutr Diet pmid:14579687
Budowski P et al. Mature milk from Israeli mothers is rich in polyunsaturated fatty acids. 1994 World Rev Nutr Diet pmid:7871809
Postle AD et al. Molecular species composition of plasma phosphatidylcholine in human pregnancy. 1994 World Rev Nutr Diet pmid:7871810
Yavin E and Green P Distribution, processing and selective esterification of essential fatty acid metabolites in the fetal brain. 1994 World Rev Nutr Diet pmid:7871815
Lien EL The ratio of linoleic acid to alpha-linolenic acid in infant formulas: current facts and future research directions. 1994 World Rev Nutr Diet pmid:7871839
Simopoulos AP Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications. 2009 World Rev Nutr Diet pmid:19696523
Holman RT Highpoints in an affair with polyunsaturated fatty acids. 1991 World Rev Nutr Diet pmid:2053355
Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Okuyama H et al. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. 2007 World Rev Nutr Diet pmid:17167285
Okuyama H and Sakai K Effects of dietary oils with extreme omega 3/omega 6 ratios--selective incorporation and differential catabolism. 1991 World Rev Nutr Diet pmid:1675826