| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Infertility, Male | D007248 | 11 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Darier Disease | D007644 | 2 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
| Leptospirosis | D007922 | 2 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Liposarcoma | D008080 | 1 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Thorax (1)
- Am. J. Physiol., Cell Physiol. (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Virtanen JK et al. | Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women. | 2012 | Osteoporos Int | pmid:22270860 |
| Morales A et al. | Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. | 2012 | J Chromatogr A | pmid:22321954 |
| Honkanen AM et al. | Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. | 2012 | J. Dairy Sci. | pmid:22365221 |
| Jadoon A et al. | Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression. | 2012 | J Affect Disord | pmid:22113178 |
| Järvinen R et al. | Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women. | 2012 | Eur J Clin Nutr | pmid:22113249 |
| Sauerwald UC et al. | Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and α-linolenic acid conversion in preterm infants. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22008957 |
| Krugner-Higby L et al. | Ulcerative dermatitis in C57BL/6 mice lacking stearoyl CoA desaturase 1. | 2012 | Comp. Med. | pmid:23043777 |
| Han SN et al. | Novel soybean oils differing in fatty acid composition alter immune functions of moderately hypercholesterolemic older adults. | 2012 | J. Nutr. | pmid:23096013 |
| Buchhaupt M et al. | Synthesis of green note aroma compounds by biotransformation of fatty acids using yeast cells coexpressing lipoxygenase and hydroperoxide lyase. | 2012 | Appl. Microbiol. Biotechnol. | pmid:21789493 |
| Nurachman Z et al. | Oil from the tropical marine benthic-diatom Navicula sp. | 2012 | Appl. Biochem. Biotechnol. | pmid:22926527 |
| Huang FC and Schwab W | Overexpression of hydroperoxide lyase, peroxygenase and epoxide hydrolase in tobacco for the biotechnological production of flavours and polymer precursors. | 2012 | Plant Biotechnol. J. | pmid:22967031 |
| Fares M et al. | ω6/ω3 Polyunsaturated fatty acid supplementations in renal cell model lead to a particular regulation through lipidome for preserved ω6/ω3 ratios. | 2012 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:22762527 |
| Cerretani L et al. | DSC evaluation of extra virgin olive oil stability under accelerated oxidative test: effect of fatty acid composition and phenol contents. | 2012 | J Oleo Sci | pmid:22687775 |
| McPherson PA et al. | A curvilinear approach to the kinetic analysis of linoleate peroxidation in aqueous liposomes by 2,2'azobis(2-amidoinopropane) dihydrochloride. | 2012 | Chem. Phys. Lipids | pmid:22841574 |
| Kuipers RS et al. | Fetal intrauterine whole body linoleic, arachidonic and docosahexaenoic acid contents and accretion rates. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22115845 |
| Brenna T | Tissue-specific LCPUFA accretion in fetal humans. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22078006 |
| Chivandi E et al. | Suppression of Caco-2 and HEK-293 cell proliferation by Kigelia africana, Mimusops zeyheri and Ximenia caffra seed oils. | 2012 Jan-Feb | In Vivo | pmid:22210722 |
| Alinezhad H et al. | Biochemical activities of acetone extracts of Hyssopus angustifolius. | 2012 Jul-Aug | Acta Pol Pharm | pmid:22876603 |
| Moghaddam AH et al. | Antioxidant, antihemolytic and nephroprotective activity of aqueous extract of Diospyros lotus seeds. | 2012 Jul-Aug | Acta Pol Pharm | pmid:22876611 |
| Mysiakina IS et al. | [Lipid composition of fungus Mucor hiemalis mycelium grown in the presence of trehalose, triacylglycerols, and itraconazole]. | 2012 Nov-Dec | Mikrobiologiia | pmid:23610922 |
| Mysiakina IS et al. | [Effect of biological factors on morphogenesis, growth, and lipid composition of fungus Mucor hiemalis mycelium]. | 2012 Nov-Dec | Mikrobiologiia | pmid:23610923 |
| Ramsden CE et al. | Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. | 2012 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22959954 |
| Ivan M et al. | Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. | 2013 | Br. J. Nutr. | pmid:22850225 |
| Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice. | 2013 | Br. J. Nutr. | pmid:22883314 |
| Cheng G et al. | Relative validity of a 3 d estimated food record in German toddlers. | 2013 | Public Health Nutr | pmid:22874634 |
| Huang X et al. | Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia. | 2013 | Clin. Cancer Res. | pmid:23493348 |
| Chukir T et al. | Shared retronasal identifications of vapor-phase 18-carbon fatty acids. | 2013 | Chem. Senses | pmid:23424022 |
| Anton SD et al. | Differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health. | 2013 | J Integr Med | pmid:23464640 |
| Zhang J et al. | Characteristics of fatty acid distribution is associated with colorectal cancer prognosis. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23465412 |
| Tarawneh AH et al. | Fatty acids with in vitro binding affinity for human opioid receptors from the fungus Emericella nidulans. | 2013 | J. Agric. Food Chem. | pmid:24147790 |
| Bae WK et al. | Docetaxel-loaded thermoresponsive conjugated linoleic acid-incorporated poloxamer hydrogel for the suppression of peritoneal metastasis of gastric cancer. | 2013 | Biomaterials | pmid:23174142 |
| Shen W et al. | Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice. | 2013 | J. Lipid Res. | pmid:23401602 |
| Saubeau G et al. | Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. | 2013 | Plant Cell Rep. | pmid:23479199 |
| Godinot N et al. | Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice. | 2013 | Neuroscience | pmid:23831422 |
| Lai MC et al. | The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. | 2013 | J. Vet. Med. Sci. | pmid:23832628 |
| Bartók T et al. | ESI-MS and MS/MS identification of the first ceramide analogues of fumonisin B₠mycotoxin from a Fusarium verticillioides culture following RP-HPLC separation. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23837460 |
| Okada Y et al. | Wing (Ib) cells in frog taste discs detect dietary unsaturated fatty acids. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23872318 |
| Song Y et al. | Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members. | 2013 | Lipids Health Dis | pmid:23879935 |
| Cao AH et al. | Composition of long chain polyunsaturated fatty acids (LC-PUFAs) in different encephalic regions and its association with behavior in spontaneous hypertensive rat (SHR). | 2013 | Brain Res. | pmid:23811335 |
| Klein-Wieringa IR et al. | Adipocytes modulate the phenotype of human macrophages through secreted lipids. | 2013 | J. Immunol. | pmid:23817431 |
| Wei J et al. | Linoleic acid attenuates endothelium-derived relaxing factor production by suppressing cAMP-hydrolyzing phosphodiesterase activity. | 2013 | Circ. J. | pmid:23883876 |
| Moloney AP et al. | Colour of fat, and colour, fatty acid composition and sensory characteristics of muscle from heifers offered alternative forages to grass silage in a finishing ration. | 2013 | Meat Sci. | pmid:23806853 |
| Lagarde M et al. | Lipidomics of essential fatty acids and oxygenated metabolites. | 2013 | Mol Nutr Food Res | pmid:23818385 |
| Cedernaes J et al. | Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet. | 2013 | Lipids Health Dis | pmid:23298201 |
| Kälber T et al. | Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. | 2013 | J. Dairy Res. | pmid:23253429 |
| Gillingham LG et al. | Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. | 2013 | Am. J. Clin. Nutr. | pmid:23221573 |
| Carro M et al. | Linoleic acid stimulates neutral lipid accumulation in lipid droplets of maturing bovine oocytes. | 2013 | Theriogenology | pmid:23273433 |
| Nelson RH et al. | Kinetics of saturated, monounsaturated, and polyunsaturated fatty acids in humans. | 2013 | Diabetes | pmid:23274886 |
| Gage SH et al. | Functionalization of monodisperse iron oxide NPs and their properties as magnetically recoverable catalysts. | 2013 | Langmuir | pmid:23234434 |
| Figueroa V et al. | Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway. | 2013 | Biochim. Biophys. Acta | pmid:23261389 |
| Li A et al. | Thermally induced isomerization of linoleic acid in soybean oil. | 2013 | Chem. Phys. Lipids | pmid:23261796 |
| Mena J et al. | Linoleic acid increases adhesion, chemotaxis, granule release, intracellular calcium mobilisation, MAPK phosphorylation and gene expression in bovine neutrophils. | 2013 | Vet. Immunol. Immunopathol. | pmid:23267746 |
| Li L et al. | A novel galanin receptor 1a gene in zebrafish: tissue distribution, developmental expression roles in nutrition regulation. | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23268327 |
| Zeng G et al. | Kinetics of heterogeneous reaction of ozone with linoleic acid and its dependence on temperature, physical state, RH, and ozone concentration. | 2013 | J Phys Chem A | pmid:23347186 |
| Raatz SK et al. | Dose-dependent consumption of farmed Atlantic salmon (Salmo salar) increases plasma phospholipid n-3 fatty acids differentially. | 2013 | J Acad Nutr Diet | pmid:23351633 |
| Khan AA et al. | Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. | 2013 | Nanomedicine (Lond) | pmid:23311988 |
| Graves JP et al. | Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily. | 2013 | Drug Metab. Dispos. | pmid:23315644 |
| Carey AN et al. | The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. | 2013 | Nutr Neurosci | pmid:23321679 |
| Ramsden CE et al. | Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. | 2013 | BMJ | pmid:23386268 |
| Calder PC | Old study sheds new light on the fatty acids and cardiovascular health debate. | 2013 | BMJ | pmid:23386269 |
| Benjamin S et al. | Conjugated linoleic acid isomers and their precursor fatty acids regulate peroxisome proliferator-activated receptor subtypes and major peroxisome proliferator responsive element-bearing target genes in HepG2 cell model. | 2013 | J Zhejiang Univ Sci B | pmid:23365010 |
| Harris WS et al. | Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23375840 |
| Chiou TY et al. | Characteristics and antioxidative ability of defatted rice bran extracts obtained using several extractants under subcritical conditions. | 2013 | J Oleo Sci | pmid:23357811 |
| Fijlstra M et al. | Reduced absorption of long-chain fatty acids during methotrexate-induced gastrointestinal mucositis in the rat. | 2013 | Clin Nutr | pmid:23102689 |
| Liu X et al. | Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation. | 2013 | Anal. Biochem. | pmid:23850559 |
| Dai J et al. | Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro. | 2013 | Lipids Health Dis | pmid:23663688 |
| Ali Q et al. | Ameliorating effects of exogenously applied proline on seed composition, seed oil quality and oil antioxidant activity of maize (Zea mays L.) under drought stress. | 2013 | Int J Mol Sci | pmid:23344043 |
| Ogata F et al. | Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). | 2013 | J Oleo Sci | pmid:23391535 |
| Ghisolfi J et al. | Nutrient intakes of children aged 1-2 years as a function of milk consumption, cows' milk or growing-up milk. | 2013 | Public Health Nutr | pmid:23098567 |
| Guo J et al. | Selective transport of long-chain fatty acids by FAT/CD36 in skeletal muscle of broilers. | 2013 | Animal | pmid:23031491 |
| Kiernan M et al. | The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. | 2013 | Reprod. Fertil. Dev. | pmid:23036717 |
| D'Angeli S et al. | Cold perception and gene expression differ in Olea europaea seed coat and embryo during drupe cold acclimation. | 2013 | New Phytol. | pmid:23078289 |
| Loizzo MR et al. | Phenolics, aroma profile, and in vitro antioxidant activity of Italian dessert passito wine from Saracena (Italy). | 2013 | J. Food Sci. | pmid:23574495 |
| Bassett JK et al. | Plasma phospholipid fatty acids, dietary fatty acids and prostate cancer risk. | 2013 | Int. J. Cancer | pmid:23575905 |
| Brouwer IA et al. | Trans fatty acids and cardiovascular health: research completed? | 2013 | Eur J Clin Nutr | pmid:23531781 |
| Mujtaba SF et al. | Singlet oxygen mediated apoptosis by anthrone involving lysosomes and mitochondria at ambient UV exposure. | 2013 | J. Hazard. Mater. | pmid:23542321 |
| Wardhani DH et al. | Inhibition kinetics of lipid oxidation of model foods by using antioxidant extract of fermented soybeans. | 2013 | Food Chem | pmid:23561179 |
| Garofalo JM et al. | Mouse mammary gland is refractory to the effects of ethanol after natural lactation. | 2013 | Comp. Med. | pmid:23561936 |
| Al-Bishri WM | Favorable effects of flaxseed supplemented diet on liver and kidney functions in hypertensive Wistar rats. | 2013 | J Oleo Sci | pmid:24005015 |
| Han L et al. | Hydroxyl radical induced by lipid in Maillard reaction model system promotes diet-derived N(ε)-carboxymethyllysine formation. | 2013 | Food Chem. Toxicol. | pmid:23959106 |
| Aboshi T et al. | Biosynthesis of linoleic acid in Tyrophagus mites (Acarina: Acaridae). | 2013 | Insect Biochem. Mol. Biol. | pmid:23973745 |
| Luo C et al. | Vegetable oil thermosets reinforced by tannin-lipid formulations. | 2013 | Acta Biomater | pmid:22975626 |
| Ramirez AM et al. | A trichome-specific linoleate lipoxygenase expressed during pyrethrin biosynthesis in pyrethrum. | 2013 | Lipids | pmid:23893337 |
| Ding CH et al. | [Extraction of fatty constituents from Tabanus bivittatus and their analysis by GC-MS]. | 2013 | Zhong Yao Cai | pmid:23901639 |
| Daud AZ et al. | The trans fatty acid content in human milk and its association with maternal diet among lactating mothers in Malaysia. | 2013 | Asia Pac J Clin Nutr | pmid:23945414 |
| Abdoul-Azize S et al. | Oro-gustatory perception of dietary lipids and calcium signaling in taste bud cells are altered in nutritionally obesity-prone Psammomys obesus. | 2013 | PLoS ONE | pmid:23936306 |
| Adachi S et al. | Increased levels of extracellular dopamine in the nucleus accumbens and amygdala of rats by ingesting a low concentration of a long-chain Fatty Acid. | 2013 | Biosci. Biotechnol. Biochem. | pmid:24200795 |
| Kummerow FA et al. | Effects of trans fats on prostacyclin production. | 2013 | Scand. Cardiovasc. J. | pmid:24228623 |
| Hashim A et al. | Antioxidant and α -amylase inhibitory property of phyllanthus virgatus L.: an in vitro and molecular interaction study. | 2013 | Biomed Res Int | pmid:23957001 |
| Stelzleni AM et al. | Effects of feeding extruded full-fat cottonseed pellets in place of tallow as a fat source for finishing heifers on feedlot performance, carcass characteristics, sensory traits, display color, and fatty acid profiles. | 2013 | J. Anim. Sci. | pmid:23893987 |
| Cvetković Z et al. | Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. | 2013 | Med. Oncol. | pmid:24085546 |
| Reinders I et al. | Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. | 2013 | Eur J Clin Nutr | pmid:24084512 |
| Navarro-Guillén C et al. | Interaction between dietary levels of LC-PUFA and vegetable oil sources in Senegalese sole (Solea senegalensis) post-larvae: puzzling results suggesting complete biosynthesis pathway from C18 PUFA to DHA. | 2013 | Commun. Agric. Appl. Biol. Sci. | pmid:25141696 |
| Smink W et al. | Effect of intake of linoleic acid and α-linolenic acid levels on conversion into long-chain polyunsaturated fatty acids in backfat and in intramuscular fat of growing pigs. | 2013 | J Anim Physiol Anim Nutr (Berl) | pmid:22463497 |
| Gharby S et al. | Can fruit-form be a marker for argan oil production? | 2013 | Nat Prod Commun | pmid:23472452 |
| Sato K et al. | Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on U46619-induced contraction in rat aorta. | 2013 | J Smooth Muscle Res | pmid:24304639 |
| De Weirdt R et al. | A simulated mucus layer protects Lactobacillus reuteri from the inhibitory effects of linoleic acid. | 2013 | Benef Microbes | pmid:24311313 |
| Okada Y et al. | Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization. | 2013 | Clin. Exp. Immunol. | pmid:24028683 |
| Del Mar Bibiloni M et al. | Dietary factors associated with subclinical inflammation among girls. | 2013 | Eur J Clin Nutr | pmid:24149444 |
| Yamagishi K et al. | Plasma fatty acid composition and incident ischemic stroke in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. | 2013 | Cerebrovasc. Dis. | pmid:23920478 |