Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Louw L et al. | Keloids: peripheral and central differences in cell morphology and fatty acid compositions of lipids. | 1997 | Adv. Exp. Med. Biol. | pmid:9322000 |
Eling TE et al. | Modulation of epidermal growth factor signal transduction by linoleic acid metabolites. | 1997 | Adv. Exp. Med. Biol. | pmid:9321970 |
Meyer C et al. | Human kidney free fatty acid and glucose uptake: evidence for a renal glucose-fatty acid cycle. | 1997 | Am. J. Physiol. | pmid:9316458 |
Chatterjee MT et al. | Alterations in cellular lipids may be responsible for the transient nature of the yeast heat shock response. | 1997 | Microbiology (Reading, Engl.) | pmid:9308188 |
Chinn KS et al. | Modulation of adjuvant-induced arthritis by dietary arachidonic acid in essential fatty acid-deficient rats. | 1997 | Lipids | pmid:9307941 |
Bolton-Smith C et al. | Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. | 1997 | Eur J Clin Nutr | pmid:9306089 |
Hayakawa F et al. | DNA cleavage reaction and linoleic acid peroxidation induced by tea catechins in the presence of cupric ion. | 1997 | Biochim. Biophys. Acta | pmid:9305782 |
Moran JH et al. | Cytotoxicity of linoleic acid diols to renal proximal tubular cells. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9299596 |
Rusnak A et al. | Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production. | 1997 | J. Bioenerg. Biomembr. | pmid:9298714 |
de Waart FG et al. | Vitamin E supplementation in elderly lowers the oxidation rate of linoleic acid in LDL. | 1997 | Atherosclerosis | pmid:9298686 |