Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kissil GW et al. | Capacity of the European eel (Anguilla anguilla) to elongate and desaturate dietary linoleic acid. | 1987 | J. Nutr. | pmid:3114442 |
| Wertz PW et al. | Essential fatty acids and epidermal integrity. | 1987 | Arch Dermatol | pmid:3310912 |
| Szekeres L | Cardioprotection by anti-ischaemic and cytoprotective drugs. | 1987 | Basic Res. Cardiol. | pmid:3311014 |
| Levay-Young BK et al. | Linoleic acid, but not cortisol, stimulates accumulation of casein by mouse mammary epithelial cells in serum-free collagen gel culture. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3317407 |
| Cardot P et al. | Essential fatty acid deficiency during pregnancy in the rat: influence of dietary carbohydrates. | 1987 | J. Nutr. | pmid:3116179 |
| Mikhailidis DP et al. | High content of dietary linoleic acid does not reduce platelet reactivity in patients with hyperlipoproteinaemia. | 1987 | Eur. J. Clin. Invest. | pmid:3106056 |
| MartÃnez M and Ballabriga A | Effects of parenteral nutrition with high doses of linoleate on the developing human liver and brain. | 1987 | Lipids | pmid:3106740 |
| Ludwig P et al. | Modelling the reaction mechanism of the reticulocyte lipoxygenase. | 1987 | Biomed. Biochim. Acta | pmid:3109405 |
| Maher ER et al. | Increased free-radical activity during haemodialysis? | 1987 | Nephrol. Dial. Transplant. | pmid:3114676 |
| Effect of parenteral linoleate on fatty acid composition of infant brain and liver. | 1987 | Nutr. Rev. | pmid:3114686 | |
| Vrignaud P and Robert J | Free fatty acid uptake is increased in doxorubicin-resistant rat glioblastoma cells. | 1987 | Biochim. Biophys. Acta | pmid:2886153 |
| Sani BP et al. | Interference of retinoic acid binding to its binding protein by omega-6 fatty acids. | 1987 | Biochem. Biophys. Res. Commun. | pmid:2820396 |
| Tilvis RS et al. | Serum lipids and fatty acids in ischemic strokes. | 1987 | Am. Heart J. | pmid:3812213 |
| Coronary heart disease and linoleic acid content of adipose tissue. | 1987 | Nutr. Rev. | pmid:3332709 | |
| Hagve TA and Christophersen BO | Sex-related differences in desaturation and chain elongation of essential fatty acids studied in isolated rat hepatocytes. | 1987 | Biochim. Biophys. Acta | pmid:3607076 |
| Persegol L and Paris R | Influence of dietary lipids and linoleic acid amounts on fatty acid content and composition of pig serum lipoproteins. | 1987 | J. Physiol. (Paris) | pmid:3430364 |
| Spann W et al. | [Effects of equal amounts of linoleic acid in orally administered, polyunsaturated phospholipids or in safflower oil on blood lipoproteins]. | 1987 | Klin. Wochenschr. | pmid:3431029 |
| Frank H et al. | Monohydroperoxides of linoleic acid in endoplasmic lipids of rats exposed to tetrachloromethane. | 1987 | Lipids | pmid:3431344 |
| McKinney M | Blockade of receptor-mediated cyclic GMP formation by hydroxyeicosatetraenoic acid. | 1987 | J. Neurochem. | pmid:3037024 |
| Setty BN et al. | 13-Hydroxyoctadecadienoic acid (13-HODE) stimulates prostacyclin production by endothelial cells. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3113422 |
| Wan JM and Grimble RF | Effect of dietary linoleate content on the metabolic response of rats to Escherichia coli endotoxin. | 1987 | Clin. Sci. | pmid:3545648 |
| Bruneau C et al. | Influence of lipid environment on insulin binding in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552053 |
| Bruneau C et al. | Modifications of cellular lipids induce insulin resistance in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552054 |
| Perez RV et al. | The effect of donor specific transfusions and dietary fatty acids on rat cardiac allograft survival. | 1987 | J. Surg. Res. | pmid:3553741 |
| Berry EM et al. | Dietary fat, plasma lipoproteins, and immune function in middle-aged American men. | 1987 | Nutr Cancer | pmid:3562291 |
| Olivi O et al. | [A new and original therapy for seborrheic dermatitis]. | 1986 May-Jun | Pediatr Med Chir | pmid:2947051 |
| Lester LA et al. | Supplemental parenteral nutrition in cystic fibrosis. | 1986 May-Jun | JPEN J Parenter Enteral Nutr | pmid:3086588 |
| Kaunitz H | Medium chain triglycerides (MCT) in aging and arteriosclerosis. | 1986 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:3519928 |
| Kummerow FA | Dietary effects of trans fatty acids. | 1986 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:3519929 |
| Fukuzumi K | Relationship between lipoperoxides and diseases. | 1986 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:3519933 |
| Koletzko B et al. | Comparison of fatty acid composition of plasma lipid fractions in well-nourished Nigerian and German infants and toddlers. | 1986 Jul-Aug | J. Pediatr. Gastroenterol. Nutr. | pmid:3090220 |
| Iriyama K et al. | Metabolism of non-protein energy-substrates in septic rats receiving parenteral nutrition. | 1986 Jan-Mar | Int Surg | pmid:3087901 |
| Gotoh K et al. | Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. | 1986 | J. Biochem. | pmid:2880840 |
| Nanji AA and Narod S | Multiple sclerosis, latitude and dietary fat: is pork the missing link? | 1986 | Med. Hypotheses | pmid:3638477 |
| Boberg M et al. | High content of dietary linoleic acid does not reduce platelet reactivity in patients with hyperlipoproteinaemia. | 1986 | Eur. J. Clin. Invest. | pmid:2938965 |
| Orchard S et al. | Poison ivy/oak dermatitis. Use of polyamine salts of a linoleic acid dimer for topical prophylaxis. | 1986 | Arch Dermatol | pmid:2942115 |
| May V and Eipper BA | Long term culture of primary rat pituitary adrenocorticotropin/endorphin-producing cells in serum-free medium. | 1986 | Endocrinology | pmid:3004908 |
| Kühn H et al. | The stoichiometry of oxygen uptake and conjugated diene formation during the dioxygenation of linoleic acid by the pure reticulocyte lipoxygenase. Evidence for aerobic hydroperoxidase activity. | 1986 | Biochim. Biophys. Acta | pmid:3006782 |
| Murphy MG | Studies of the regulation of basal adenylate cyclase activity by membrane polyunsaturated fatty acids in cultured neuroblastoma. | 1986 | J. Neurochem. | pmid:3011993 |
| Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
| Kher V et al. | Protective effect of polyunsaturated fatty acid supplementation in apoferritin induced murine glomerulonephritis. | 1986 | Prostaglandins Leukot Med | pmid:3014561 |
| Alexander JW et al. | The importance of lipid type in the diet after burn injury. | 1986 | Ann. Surg. | pmid:3015058 |
| Yamamoto T et al. | Purification of the two forms of the high-molecular-weight neutral proteinase ingensin from rat liver. | 1986 | Biochim. Biophys. Acta | pmid:3015226 |
| Kelly RA et al. | Identification of NaK-ATPase inhibitors in human plasma as nonesterified fatty acids and lysophospholipids. | 1986 | J. Biol. Chem. | pmid:3017943 |
| Galland L | Increased requirements for essential fatty acids in atopic individuals: a review with clinical descriptions. | 1986 | J Am Coll Nutr | pmid:2424959 |
| Narce M et al. | [Chronologic studies of the effects of a hypoproteinic diet followed by an equilibrated diet on delta-6 and delta-5 desaturations of linoleic acid in liver microsomes in the rat]. | 1986 | Arch. Int. Physiol. Biochim. | pmid:2430531 |
| Iizuka Y and Murphy MJ | Colony formation of granulocyte (CFU-g) and macrophage (CFU-m) precursors in serum- and albumin-free culture: effect of transferrin on clonal growth. | 1986 | Exp. Cell Biol. | pmid:2433167 |
| Kääpä P et al. | Dietary fatty acids and platelet thromboxane production in puerperal women and their offspring. | 1986 | Am. J. Obstet. Gynecol. | pmid:3089014 |
| Maddaiah VT and Clejan S | Growth hormone and liver mitochondria: time course of effects on respiration and fatty acid composition in hypophysectomized rats. | 1986 | Endocrinology | pmid:2941269 |
| Connor HD et al. | A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3026385 |
| Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
| van Staveren WA et al. | Validity of the fatty acid composition of subcutaneous fat tissue microbiopsies as an estimate of the long-term average fatty acid composition of the diet of separate individuals. | 1986 | Am. J. Epidemiol. | pmid:3946391 |
| Nijssen JG and van den Bosch H | Cytosol-stimulated remodeling of phosphatidylcholine in rat lung microsomes. | 1986 | Biochim. Biophys. Acta | pmid:3947653 |
| Kryvi H et al. | Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet. | 1986 | Biochim. Biophys. Acta | pmid:3947675 |
| De Villiers M and Lochner A | Mitochondrial Ca2+ fluxes: role of free fatty acids, acyl-CoA and acylcarnitine. | 1986 | Biochim. Biophys. Acta | pmid:3955069 |
| Fressinaud C et al. | Fatty acid composition of endoneurium and perineurium from adult rat sciatic nerve. | 1986 | J. Neurochem. | pmid:3958717 |
| Becker W and Bruce A | Retention of linoleic acid in carcass lipids of rats fed different levels of essential fatty acids. | 1986 | Lipids | pmid:3959773 |
| Otsuki T et al. | Two geometrical isomers of linoleic acid: improved total syntheses. | 1986 | Lipids | pmid:3959777 |
| Madison KC et al. | Lipid composition of cultured murine keratinocytes. | 1986 | J. Invest. Dermatol. | pmid:3090156 |
| Kort WJ et al. | Influence of the linoleic acid content of the diet on tumor growth in transplantable rat tumor models. | 1986 | Ann. Nutr. Metab. | pmid:3963748 |
| Ishiura S et al. | Reticulocyte lipoxygenase, ingensin, and ATP-dependent proteolysis. | 1986 | FEBS Lett. | pmid:3086125 |
| Beneytout JL et al. | Effect of isoquinoline alkaloids on soybean lipoxygenase activity in vitro. | 1986 | Prostaglandins | pmid:3086939 |
| Coene MC et al. | Inhibition of rabbit platelet activation by lipoxygenase products of arachidonic and linoleic acid. | 1986 | Thromb. Res. | pmid:3087009 |
| Riemersma RA et al. | Linoleic acid content in adipose tissue and coronary heart disease. | 1986 | Br Med J (Clin Res Ed) | pmid:3087455 |
| Rapoport S et al. | Hydroperoxyfatty acids inactivate the reticulocyte lipoxygenase independently of a hydroperoxidase reaction. | 1986 | FEBS Lett. | pmid:3087777 |
| Hansen HS et al. | Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats. | 1986 | Biochim. Biophys. Acta | pmid:3092868 |
| Chambaz J et al. | Essential fatty acid uptake and esterification in primary culture of rat hepatocytes. | 1986 | Biochim. Biophys. Acta | pmid:3092869 |
| Kanofsky JR and Axelrod B | Singlet oxygen production by soybean lipoxygenase isozymes. | 1986 | J. Biol. Chem. | pmid:3080416 |
| Renner F et al. | Effect of saturated and unsaturated lipid on the composition of mesenteric triglyceride-rich lipoproteins in the rat. | 1986 | J. Lipid Res. | pmid:3083032 |
| Innis SM | Effect of total parenteral nutrition with linoleic acid-rich emulsions on tissue omega 6 and omega 3 fatty acids in the rat. | 1986 | Lipids | pmid:3083173 |
| Kanazawa K et al. | The effect of orally administered secondary autoxidation products of linoleic acid on the activity of detoxifying enzymes in the rat liver. | 1986 | Biochim. Biophys. Acta | pmid:3768385 |
| Montalto MB and Benson JD | Nutrient intakes of older infants: effect of different milk feedings. | 1986 | J Am Coll Nutr | pmid:3771945 |
| Feingold KR et al. | Effect of essential fatty acid deficiency on cutaneous sterol synthesis. | 1986 | J. Invest. Dermatol. | pmid:3772153 |
| Jensen GE and Clausen J | Glutathione peroxidase activity, associated enzymes and substrates in blood cells from patients with multiple sclerosis--effects of antioxidant supplementation. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3776606 |
| Kapoulas VM and Andrikopoulos NK | Detection of olive oil adulteration with linoleic acid-rich oils by reversed-phase high-performance liquid chromatography. | 1986 | J. Chromatogr. | pmid:3782323 |
| Jones DB et al. | Indirect evidence of impairment of platelet desaturase enzymes in diabetes mellitus. | 1986 | Horm. Metab. Res. | pmid:3013745 |
| Hennig B et al. | Linoleic acid hydroperoxide increases the transfer of albumin across cultured endothelial monolayers. | 1986 | Arch. Biochem. Biophys. | pmid:3729421 |
| Marshall MW et al. | Effects of low fat diets varying in P/S ratio on nutrient intakes, fecal excretion, blood chemistry profiles, and fatty acids of adult men. | 1986 | J Am Coll Nutr | pmid:3734273 |
| Parsons HG et al. | Modulation of human erythrocyte shape and fatty acids by diet. | 1986 | Biochim. Biophys. Acta | pmid:3741859 |
| Roguet R et al. | In vivo distribution of linoleic acid in hairless rat skin following topical administration. | 1986 | Arch. Dermatol. Res. | pmid:3789807 |
| Kukreja RC et al. | PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. | 1986 | Circ. Res. | pmid:3028671 |
| Wertz PW and Downing DT | Linoleate content of epidermal acylglucosylceramide in newborn, growing and mature mice. | 1986 | Biochim. Biophys. Acta | pmid:3707979 |
| Vericel E et al. | Effects of linoleic acid and gamma-linolenic acid intake on platelet functions in elderly people. | 1986 | Thromb. Res. | pmid:3715813 |
| Hajarine M and Lagarde M | Studies on polyenoic acid incorporation into human platelet lipid stores: interactions with linoleic and arachidonic acids. | 1986 | Biochim. Biophys. Acta | pmid:3719006 |
| Dowd TC et al. | Diabetic retinopathy: different risk factors for exudates and haemorrhages. | 1986 | Int Ophthalmol | pmid:3721707 |
| Awad AB and Chattopadhyay JP | Effect of dietary saturated fatty acids on intracellular free fatty acids and kinetic properties of hormone-sensitive lipase of rat adipocytes. | 1986 | J. Nutr. | pmid:3723204 |
| Okabe H et al. | Effects of anti-convulsants on fatty acid metabolism in human serum. | 1986 | Tohoku J. Exp. Med. | pmid:3705068 |
| Gabor H and Abraham S | Effect of dietary menhaden oil on tumor cell loss and the accumulation of mass of a transplantable mammary adenocarcinoma in BALB/c mice. | 1986 | J. Natl. Cancer Inst. | pmid:3458958 |
| Elliott GR et al. | Linoleic and dihomo-gamma-linolenic acids modulate granuloma growth and granuloma macrophage eicosanoid release. | 1986 | Eur. J. Pharmacol. | pmid:3460810 |
| Lee SH and Clandinin MT | Effect of dietary fat on the utilization of fatty acids by myocardial tissue in the rat. | 1986 | J. Nutr. | pmid:3794820 |
| Murakami K et al. | Protein kinase C activation by cis-fatty acid in the absence of Ca2+ and phospholipids. | 1986 | J. Biol. Chem. | pmid:3096987 |
| Siguel EN et al. | Monitoring the optimal infusion of intravenous lipids. Detection of essential fatty acid deficiency. | 1986 | Arch. Pathol. Lab. Med. | pmid:2875703 |
| Szebeni J et al. | Plasma fatty acid pattern including diene-conjugated linoleic acid in ethanol users and patients with ethanol-related liver disease. | 1986 | Alcohol. Clin. Exp. Res. | pmid:3101533 |
| Morson LA and Clandinin MT | Diets varying in linoleic and linolenic acid content alter liver plasma membrane lipid composition and glucagon-stimulated adenylate cyclase activity. | 1986 | J. Nutr. | pmid:2879899 |
| Andre JC and Funk MO | Determination of stereochemistry in the fatty acid hydroperoxide products of lipoxygenase catalysis. | 1986 | Anal. Biochem. | pmid:3101541 |
| Heleniak EP and Lamola SW | A new prostaglandin disturbance syndrome in schizophrenia: delta-6-pyroluria. | 1986 | Med. Hypotheses | pmid:3520252 |
| Kovár J and Franĕk F | Serum-free medium for hybridoma and parental myeloma cell cultivation. | 1986 | Meth. Enzymol. | pmid:3523123 |
| Guesry PR et al. | Nutritional advantages of constituents of infant formulae formerly called "humanised". | 1986 | Reprod Nutr Dev | pmid:3523658 |
| Abeywardena MY et al. | Effects of variable linoleate intake on aortic PGI2-like activity and fatty acid composition: difference between rat and marmoset (Callithrix jacchus). | 1986 | Prostaglandins Leukot Med | pmid:3103139 |
| Stewart ME et al. | Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. | 1986 | J. Invest. Dermatol. | pmid:2946783 |