Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Roy R and Bélanger A | ZR-75-1 breast cancer cells generate nonconjugated steroids from low density lipoprotein-incorporated lipoidal dehydroepiandrosterone. | 1993 | Endocrinology | pmid:8344206 |
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Buchanan MR and Brister SJ | Altering vessel wall fatty acid metabolism: a new strategy for antithrombotic treatment. | 1993 | Semin. Thromb. Hemost. | pmid:8356461 |
Zheng RL et al. | Inhibition of the autoxidation of linoleic acid by phenylpropanoid glycosides from Pedicularis in micelles. | 1993 | Chem. Phys. Lipids | pmid:8358852 |
Chang WC et al. | Induction of arachidonate 12-lipoxygenase mRNA by epidermal growth factor in A431 cells. | 1993 | J. Biol. Chem. | pmid:8360167 |
Davis PA et al. | A linoleate-enriched cheese product reduces low-density lipoprotein in moderately hypercholesterolemic adults. | 1993 | Ann. Intern. Med. | pmid:8363165 |
Rabinowitch HD et al. | Escherichia coli produces linoleic acid during late stationary phase. | 1993 | J. Bacteriol. | pmid:8366020 |
Hong CY et al. | Linoleate-rich triacylglycerol in Panax pseudo-ginseng improves erythrocyte deformability in vitro. | 1993 | Planta Med. | pmid:8372148 |
Black JM and Kinsella JE | Dietary n-3 fatty acids alter murine peritoneal macrophage cytotoxicity. | 1993 | Ann. Nutr. Metab. | pmid:8373135 |
van Zoeren-Grobben D et al. | Lipid peroxidation in human milk and infant formula: effect of storage, tube feeding and exposure to phototherapy. | 1993 | Acta Paediatr. | pmid:8374211 |
Sigurdson SL and Ip MM | Casein accumulation by rat mammary epithelial cells grown within a reconstituted basement membrane is modulated by fatty acids in a hormone- and time-dependent manner. | 1993 | Exp. Cell Res. | pmid:8375465 |
Kirchgessner M and Müller HL | [The effect of palmitic, oleic and linoleic acids on thermogenesis in the model experiment in sows]. | 1993 | Z Ernahrungswiss | pmid:8379216 |
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James MJ et al. | Simple relationships exist between dietary linoleate and the n-6 fatty acids of human neutrophils and plasma. | 1993 | Am. J. Clin. Nutr. | pmid:8379505 |
Brinkmeier H et al. | Specific modifications of the membrane fatty acid composition of human myotubes and their effects on the muscular sodium channels. | 1993 | Biochim. Biophys. Acta | pmid:8380720 |
Tisdale MJ | Mechanism of lipid mobilization associated with cancer cachexia: interaction between the polyunsaturated fatty acid, eicosapentaenoic acid, and inhibitory guanine nucleotide-regulatory protein. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8380931 |
Poisson JP et al. | Effect of salt-loading and spontaneous hypertension on in vitro metabolism of [1-14C]linoleic and [2-14C]dihomo-gamma-linolenic acids. | 1993 | Biochem. Med. Metab. Biol. | pmid:8382502 |
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Wolever TM | Comments on "Treatment of diabetic neuropathy with gamma-linolenic acid" by The gamma-Linolenic Multicenter Trial Group. | 1993 | Diabetes Care | pmid:8404440 |
Kleinveld HA et al. | Oxidation resistance, oxidation rate, and extent of oxidation of human low-density lipoprotein depend on the ratio of oleic acid content to linoleic acid content: studies in vitamin E deficient subjects. | 1993 | Free Radic. Biol. Med. | pmid:8406127 |
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Seidelin KN et al. | Percentage distribution of fatty acids in subcutaneous adipose tissue of patients with peptic ulcer disease. | 1993 | Am. J. Clin. Nutr. | pmid:8416668 |
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Bandyopadhyay GK et al. | Role of polyunsaturated fatty acids as signal transducers: amplification of signals from growth factor receptors by fatty acids in mammary epithelial cells. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8424125 |
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Clark RM and Hundrieser KE | A lack of correlation among fatty acids associated with different lipid classes in human milk. | 1993 | Lipids | pmid:8441341 |
Batna A et al. | The occurrence of furan fatty acids in Isochrysis sp. and Phaeodactylum tricornutum. | 1993 | Biochim. Biophys. Acta | pmid:8443233 |
Oliw EH | bis-Allylic hydroxylation of linoleic acid and arachidonic acid by human hepatic monooxygenases. | 1993 | Biochim. Biophys. Acta | pmid:8443245 |
Kakita N et al. | Induction of gelatinolytic neutral proteinase secretion by lipid peroxide in cultured mesangial cells. | 1993 | Nephron | pmid:8446258 |
Hong CY et al. | Effect of pravastatin on fatty acid profile of low density lipoprotein in patients with hypercholesterolemia. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8446653 |
Band AM et al. | The mechanism of arachidonic acid-induced insulin secretion from rat islets of Langerhans. | 1993 | Biochim. Biophys. Acta | pmid:8452880 |
Vaughan PF et al. | Effect of inhibitors of eicosanoid metabolism on release of [3H]noradrenaline from the human neuroblastoma, SH-SY5Y. | 1993 | J. Neurochem. | pmid:8455030 |
Lecerf J et al. | Variations in the fatty acid composition of lipid classes from lipoproteins in elderly women. | 1993 | Atherosclerosis | pmid:8457263 |
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van Haaster CM et al. | Formation of prostanoids and hydroxy fatty acids by stimulated peritoneal mast cells: role of the dietary fat type in rat. | 1993 | Biochim. Biophys. Acta | pmid:8466942 |
Lomnitski L et al. | The interaction between beta-carotene and lipoxygenase in plant and animal systems. | 1993 | Biochim. Biophys. Acta | pmid:8481396 |
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