Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- J. Lipid Res. (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sammon AM | Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10410386 |
| Vaddadi KS | The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. | 1981 | Prostaglandins Med | pmid:6269135 |
| Decsi T et al. | Low contribution of n-3 polyunsaturated fatty acids to plasma and erythrocyte membrane lipids in diabetic young adults. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17321122 |
| Stachowska E et al. | Exchange of unsaturated fatty acids between adipose tissue and atherosclerotic plaque studied with artificial neural networks. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:14643180 |
| Tu WC et al. | Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20573490 |
| Noguchi M et al. | Effects of indomethacin with or without linoleic acid on human breast cancer cells in vitro. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7644559 |
| Matsuo N et al. | Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951990 |
| Whelan J | The health implications of changing linoleic acid intakes. | 2008 Sep-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18990554 |
| Fritsche KL | Too much linoleic acid promotes inflammation-doesn't it? | 2008 Sep-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18990555 |
| Ober MD and Hart CM | Attenuation of oxidant-mediated endothelial cell injury with docosahexaenoic acid: the role of intracellular iron. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774176 |
| Wander RC et al. | Influence of long-chain polyunsaturated fatty acids on oxidation of low density lipoprotein. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774178 |
| Gueck T et al. | Effects of essential fatty acids on mediators of mast cells in culture. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711248 |
| Nixon JB et al. | Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711249 |
| Pasqualini ME et al. | Association between E-cadherin expression by human colon, bladder and breast cancer cells and the 13-HODE:15-HETE ratio. A possible role of their metastatic potential. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538085 |
| Adam O et al. | Impact of linoleic acid intake on arachidonic acid formation and eicosanoid biosynthesis in humans. | 2008 Sep-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18973995 |
| Angela Liou Y and Innis SM | Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-gamma-linolenic and eicosapentaenoic acid in plasma of adult men. | 2009 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19356914 |
| McKenzie KE et al. | Omega-3 and omega-6 fatty acids and PGE2 stimulate the growth of normal but not tumor mouse mammary epithelial cells: evidence for alterations in the signaling pathways in tumor cells. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7535935 |
| Wenger FA et al. | Does alpha-linolenic acid in combination with linoleic acid influence liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters? | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10913224 |
| Ramchurren N and Karmali R | Effects of gamma-linolenic and dihomo-gamma-linolenic acids on 7,12-dimethylbenz(alpha)anthracene-induced mammary tumors in rats. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480079 |
| Kuipers RS et al. | Fetal intrauterine whole body linoleic, arachidonic and docosahexaenoic acid contents and accretion rates. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22115845 |
| Mouradian M et al. | Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. | 2014 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24374147 |
| Vancassel S et al. | Plasma fatty acid levels in autistic children. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487301 |
| Harris MA et al. | Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487304 |
| Cunnane SC and Guesnet P | Linoleic acid recommendations--A house of cards. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21963263 |
| Tribole E | What happened to do no harm? The issue of dietary omega-6 fatty acids. | 2009 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19147337 |
| Pregnolato P et al. | Effect of diets containing different amounts of precursor and derivative fatty acids on serum TXB2. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8981629 |
| Rosing U and Olund A | Endometrial content of prostaglandin precursors during the menstrual cycle. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2780764 |
| Ramsden CE et al. | Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. | 2012 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22959954 |
| Kawakami Y et al. | Antiproliferative activity of guava leaf extract via inhibition of prostaglandin endoperoxide H synthase isoforms. | 2009 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19457650 |
| Tonogai Y and Tai HH | Quantitation of 13-hydroxyoctadecadienoic acid (13-HODE) by radioimmunoassay. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2111553 |
| Goodfriend TL et al. | An oxidized derivative of linoleic acid affects aldosterone secretion by adrenal cells in vitro. | 2002 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12324236 |
| Okui T et al. | Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. | 2011 Sep-Oct | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21723718 |
| Risé P et al. | Different patterns characterize Omega 6 and Omega 3 long chain polyunsaturated fatty acid levels in blood from Italian infants, children, adults and elderly. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23910046 |
| Cunnane SC et al. | Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471127 |
| Salem N et al. | In vivo conversion of linoleic acid to arachidonic acid in human adults. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471130 |
| Hover CG and Kulkarni AP | A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780874 |
| Charnock JS | Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780878 |
| van der Schouw YT et al. | Fatty acid composition of serum lipids of mothers and their babies after normal and hypertensive pregnancies. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1815240 |
| Smith DE and Salerno JW | Selective growth inhibition of a human malignant melanoma cell line by sesame oil in vitro. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502251 |
| Mayer M | Linoleic-acid-dependent slowing of erythrocyte sedimentation in multiple sclerosis. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1815242 |
| Krumhardt B and Dupont J | The relationship between thromboxane and cytosolic calcium modifiers in rat platelets. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1652770 |
| Porras-Reyes BH et al. | Essential fatty acids are not required for wound healing. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1603819 |
| Punchard NA et al. | Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765976 |
| Williams LL et al. | Quantitative association between altered plasma esterified omega-6 fatty acid proportions and psychological stress. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1461929 |
| Kuipers RS et al. | Milk in the island of Chole [Tanzania] is high in lauric, myristic, arachidonic and docosahexaenoic acids, and low in linoleic acid reconstructed diet of infants born to our ancestors living in tropical coastal regions. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17383169 |
| Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |
| Brestel EP and Koes MT | Heparin inhibits the "quasi-lipoxygenase" activity of hemoglobin toward linoleic acid by oxidant scavenging. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2500671 |
| Crandall DL et al. | Effect of varying concentrations of linoleic acid on alpha-adrenoceptor responses in spontaneously hypertensive rats. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2845438 |
| Kritchevsky D | Trans fatty acids and cardiovascular risk. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430386 |
| Renaud SC | Dietary management of cardiovascular diseases. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430390 |