| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis Obliterans | D001162 | 8 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Protein-Energy Malnutrition | D011502 | 9 associated lipids |
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Retinal Degeneration | D012162 | 9 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Johnson GH and Fritsche K | Effect of dietary linoleic acid on markers of inflammation in healthy persons: a systematic review of randomized controlled trials. | 2012 | J Acad Nutr Diet | pmid:22889633 |
| Chiou TY et al. | Extraction of defatted rice bran with subcritical aqueous acetone. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22878207 |
| Ross GR et al. | Fatty acid profile of pig meat after probiotic administration. | 2012 | J. Agric. Food Chem. | pmid:22506842 |
| Ties P and Barringer S | Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh. | 2012 | J. Food Sci. | pmid:22757705 |
| Lan M et al. | [GC-MS analysis of chemical components in seeds oil from Croton tiglium]. | 2012 | Zhong Yao Cai | pmid:23252276 |
| Xue C et al. | Differences in lipid characteristics among populations: low-temperature adaptability of ayu, Plecoglossus altivelis. | 2012 | Lipids | pmid:22120618 |
| Jernerén F et al. | Linolenate 9R-dioxygenase and allene oxide synthase activities of Lasiodiplodia theobromae. | 2012 | Lipids | pmid:22048860 |
| Rohr-Udilova N et al. | Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. | 2012 | Hepatology | pmid:22105228 |
| Smith AN et al. | Unsaturated fatty acids induce mesenchymal stem cells to increase secretion of angiogenic mediators. | 2012 | J. Cell. Physiol. | pmid:22105830 |
| Ozcan MM et al. | Characteristics of grape seed and oil from nine Turkish cultivars. | 2012 | Nat. Prod. Res. | pmid:22132714 |
| Jung CH et al. | The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells. | 2012 | Inflammation | pmid:22124782 |
| Coimbra MC and Jorge N | Fatty acids and bioactive compounds of the pulps and kernels of Brazilian palm species, guariroba (Syagrus oleraces), jerivá (Syagrus romanzoffiana) and macaúba (Acrocomia aculeata). | 2012 | J. Sci. Food Agric. | pmid:21922463 |
| Shah BP et al. | TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:21998136 |
| Marincola FC et al. | A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis: preliminary results. | 2012 | J. Matern. Fetal. Neonatal. Med. | pmid:23025771 |
| Ruparel S et al. | The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. | 2012 | Mol Pain | pmid:23006841 |
| Martorell P et al. | Caenorhabditis elegans as a model to study the effectiveness and metabolic targets of dietary supplements used for obesity treatment: the specific case of a conjugated linoleic acid mixture (Tonalin). | 2012 | J. Agric. Food Chem. | pmid:23072574 |
| Hu ZP et al. | Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. | 2012 | J. Proteome Res. | pmid:23078235 |
| Saracoglu HT et al. | Evaluation of oil content and fatty acid composition of five endemic Bupleurum species growing in the Central Anatolia region of Turkey. | 2012 | Nat. Prod. Res. | pmid:21870933 |
| Lee S et al. | Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1. | 2012 | Br. J. Nutr. | pmid:21846428 |
| de Goede J et al. | Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20,000 middle-aged men and women in the Netherlands. | 2012 | Br. J. Nutr. | pmid:21816117 |
| Kim YS et al. | In vitro protective effects of Thymus quinquecostatus Celak extracts on t-BHP-induced cell damage through antioxidant activity. | 2012 | Food Chem. Toxicol. | pmid:22921350 |
| Mukherjee S et al. | NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death. | 2012 | J. Biol. Chem. | pmid:22923617 |
| Le Maux S et al. | β-Lactoglobulin as a molecular carrier of linoleate: characterization and effects on intestinal epithelial cells in vitro. | 2012 | J. Agric. Food Chem. | pmid:22924475 |
| Dubey V et al. | Appraisal of conjugated linoleic acid production by probiotic potential of Pediococcus spp. GS4. | 2012 | Appl. Biochem. Biotechnol. | pmid:22971829 |
| Florence AC et al. | Fatty acid profile, trans-octadecenoic, α-linolenic and conjugated linoleic acid contents differing in certified organic and conventional probiotic fermented milks. | 2012 | Food Chem | pmid:22980792 |
| Rasic-Milutinovic Z et al. | Lower serum paraoxonase-1 activity is related to linoleic and docosahexanoic fatty acids in type 2 diabetic patients. | 2012 | Arch. Med. Res. | pmid:22222492 |
| Regensburger J et al. | Fatty acids and vitamins generate singlet oxygen under UVB irradiation. | 2012 | Exp. Dermatol. | pmid:22229443 |
| Gursoy O et al. | The effect of using different probiotic cultures on conjugated linoleic acid (CLA) concentration and fatty acid composition of white pickle cheese. | 2012 | Int J Food Sci Nutr | pmid:22166042 |
| Beevi SS et al. | Polyphenolics profile and antioxidant properties of Raphanus sativus L. | 2012 | Nat. Prod. Res. | pmid:21714734 |
| Zengin G et al. | Composition of essential oil and antioxidant capacity of Centaurea drabifolia Sm. subsp. detonsa (Bornm.) Wagenitz, endemic to Turkey. | 2012 | Nat. Prod. Res. | pmid:21714737 |
| Park EY et al. | Effects of peptide fractions with different isoelectric points from wheat gluten hydrolysates on lipid oxidation in pork meat patties. | 2012 | J. Agric. Food Chem. | pmid:22747172 |
| Sajid ZI et al. | Antioxidant, antimicrobial properties and phenolics of different solvent extracts from bark, leaves and seeds of Pongamia pinnata (L.) Pierre. | 2012 | Molecules | pmid:22466852 |
| Shindo T et al. | Effective induction of oral anaphylaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate. | 2012 | J Toxicol Sci | pmid:22467021 |
| Shimomoto T et al. | Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet. | 2012 | J. Gastroenterol. | pmid:22467055 |
| Pestana JM et al. | Effect of slaughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers, and nutritional value of intramuscular fat in organic beef. | 2012 | J. Sci. Food Agric. | pmid:22473659 |
| Kuipers RS et al. | Gestational age dependent changes of the fetal brain, liver and adipose tissue fatty acid compositions in a population with high fish intakes. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22425685 |
| Gören AC et al. | Fatty acid composition and chemotaxonomic evaluation of species of Stachys. | 2012 | Nat. Prod. Res. | pmid:21859257 |
| Maqbool A et al. | Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22699835 |
| Li D et al. | Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings. | 2012 | Int J Nanomedicine | pmid:23269869 |
| Ladeira MM et al. | Lipids in the diet and the fatty acid profile in beef: a review and recent patents on the topic. | 2012 | Recent Pat Food Nutr Agric | pmid:22702746 |
| Hill S et al. | Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation. | 2012 | Free Radic. Biol. Med. | pmid:22705367 |
| Kamitani S et al. | Differences between group X and group V secretory phospholipase A(2) in lipolytic modification of lipoproteins. | 2012 | Cell. Mol. Biol. Lett. | pmid:22706677 |
| Roongpisuthipong W et al. | Essential fatty acid deficiency while a patient receiving fat regimen total parenteral nutrition. | 2012 | BMJ Case Rep | pmid:22707694 |
| Ren HT et al. | Influence of dietary fatty acids on muscle fatty acid composition and expression levels of Δ6 desaturase-like and Elovl5-like elongase in common carp (Cyprinus carpio var. Jian). | 2012 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:22677415 |
| Monteiro J et al. | Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. | 2012 | Lipids Health Dis | pmid:22642787 |
| Yu T et al. | Activation of oral trigeminal neurons by fatty acids is dependent upon intracellular calcium. | 2012 | Pflugers Arch. | pmid:22644615 |
| de Sousa Ferreira Soares G et al. | Spectroscopic and thermooxidative analysis of organic okra oil and seeds from Abelmoschus esculentus. | 2012 | ScientificWorldJournal | pmid:22645459 |
| Wiebe MG et al. | Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates. | 2012 | BMC Biotechnol. | pmid:22646156 |
| Xie J et al. | Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. | 2012 | Nat. Prod. Res. | pmid:21707231 |
| Lasa A et al. | The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. | 2011 Sep-Oct | Nutr Hosp | pmid:22072344 |
| Okui T et al. | Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. | 2011 Sep-Oct | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21723718 |
| Mujtaba SF et al. | Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities. | 2011 Sep-Oct | Photochem. Photobiol. | pmid:21668866 |
| Ramandi NF et al. | Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. | 2011 Nov-Dec | J. Food Sci. | pmid:22416687 |
| Olszewska MA | Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125960 |
| Olszewska MA | In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125961 |
| Kezutyte T et al. | Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125963 |
| China R et al. | In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. | 2011 Nov-Dec | J. Food Sci. | pmid:22416691 |
| Permiakova MD and Trufanov VA | [Effect of soybean lipoxygenae on baking properties of wheat flour]. | 2011 May-Jun | Prikl. Biokhim. Mikrobiol. | pmid:21790037 |
| Qu WX et al. | Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. | 2011 May-Jun | Phytochem Anal | pmid:20848395 |
| Lam YY et al. | Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. | 2011 Jul-Aug | Biochim. Biophys. Acta | pmid:21570480 |
| de Luis DA et al. | Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients. | 2011 Jul-Aug | Nutr Hosp | pmid:22470031 |
| Aluf Y et al. | Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. | 2011 Jul-Aug | Neuropharmacology | pmid:21414328 |
| Lasa A et al. | Effects of trans-10,cis-12 CLA on liver size and fatty acid oxidation under energy restriction conditions in hamsters. | 2011 | Nutrition | pmid:20619605 |
| Tan B et al. | Dietary L-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle. | 2011 | J. Nutr. Biochem. | pmid:20619625 |
| de Lima-Salgado TM et al. | Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage. | 2011 | Cell Biochem. Biophys. | pmid:20809180 |
| Gelhaus SL et al. | Cellular lipid extraction for targeted stable isotope dilution liquid chromatography-mass spectrometry analysis. | 2011 | J Vis Exp | pmid:22127066 |
| Andreu I et al. | Probing lipid peroxidation by using linoleic acid and benzophenone. | 2011 | Chemistry | pmid:21793062 |
| Shibata H et al. | Effect of supplementation of soy sauce oil and Ca salts of fatty acids on rumen fermentation, milk production and conjugated linoleic acid in milk of dairy cows. | 2011 | Anim. Sci. J. | pmid:21794014 |
| Prasad A and PospÃÅ¡il P | Linoleic acid-induced ultra-weak photon emission from Chlamydomonas reinhardtii as a tool for monitoring of lipid peroxidation in the cell membranes. | 2011 | PLoS ONE | pmid:21799835 |
| Li YC et al. | Effects of conjugated linoleic acid on cleavage of amyloid precursor protein via PPARγ. | 2011 | Neurol. Sci. | pmid:21800078 |
| Cai W et al. | 3,4,4'-Trihydroxy-trans-stilbene, an analogue of resveratrol, is a potent antioxidant and cytotoxic agent. | 2011 | Free Radic. Res. | pmid:21974738 |
| Gibson R and Makrides M | α-Linolenate reduces the dietary requirement for linoleate in the growing rat. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22019216 |
| Arawwawala M et al. | In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. | 2011 | Acta. Biol. Hung. | pmid:21840826 |
| Martinchik AN | [Nutritional value of sesame seeds]. | 2011 | Vopr Pitan | pmid:21842753 |
| Danish HH et al. | Hydrogen tunneling steps in cyclooxygenase-2 catalysis. | 2011 | J. Am. Chem. Soc. | pmid:21902213 |
| Bowden JA et al. | Electrospray ionization tandem mass spectrometry of sodiated adducts of cholesteryl esters. | 2011 | Lipids | pmid:21904795 |
| Shchepinov MS et al. | Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease. | 2011 | Toxicol. Lett. | pmid:21906664 |
| Aktumsek A et al. | Screening for in vitro antioxidant properties and fatty acid profiles of five Centaurea L. species from Turkey flora. | 2011 | Food Chem. Toxicol. | pmid:21878362 |
| Guesnet P et al. | α-Linolenate reduces the dietary requirement for linoleate in the growing rat. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21880475 |
| Hanada H et al. | Induction of apoptosis and lipogenesis in human preadipocyte cell line by n-3 PUFAs. | 2011 | Cell Biol. Int. | pmid:20812919 |
| Vinaixa M et al. | Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. | 2011 | PLoS ONE | pmid:22194988 |
| Chen Q et al. | Delta-6 desaturase from borage converts linoleic acid to gamma-linolenic acid in HEK293 cells. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21679695 |
| Pink RC et al. | Molecular basis for maize as a risk factor for esophageal cancer in a South African population via a prostaglandin E2 positive feedback mechanism. | 2011 | Nutr Cancer | pmid:21667399 |
| Morganti P et al. | Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial. | 2011 | Int J Cosmet Sci | pmid:21668835 |
| Narwaley M et al. | Drug-induced protein free radical formation is attenuated by unsaturated fatty acids by scavenging drug-derived phenyl radical metabolites. | 2011 | Chem. Res. Toxicol. | pmid:21671642 |
| Göçer H and Gülçin I | Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties. | 2011 | Int J Food Sci Nutr | pmid:21631390 |
| Lautenslager GT et al. | Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin. | 2011 | Metab. Clin. Exp. | pmid:21632076 |
| Martins SV et al. | Dietary conjugated linoleic acid isomers change the unsaturation degree of hepatic fatty acids in neutral lipids but not in polar lipids. | 2011 | Nutr Res | pmid:21481719 |
| Negrini R and Mezzenga R | pH-responsive lyotropic liquid crystals for controlled drug delivery. | 2011 | Langmuir | pmid:21452814 |
| Zouboulis CC et al. | Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis. | 2011 | Br. J. Dermatol. | pmid:21457203 |
| Ferreira TC et al. | Cell density-dependent linoleic acid toxicity to Saccharomyces cerevisiae. | 2011 | FEMS Yeast Res. | pmid:21457450 |
| Sala-Vila A et al. | Inverse association between serum phospholipid oleic acid and insulin resistance in subjects with primary dyslipidaemia. | 2011 | Clin Nutr | pmid:21458117 |
| Li M et al. | Isolation of a novel C18-Δ9 polyunsaturated fatty acid specific elongase gene from DHA-producing Isochrysis galbana H29 and its use for the reconstitution of the alternative Δ8 pathway in Saccharomyces cerevisiae. | 2011 | Biotechnol. Lett. | pmid:21538137 |
| Ueda Y et al. | Effect of dietary lipids on longevity and memory in the SAMP8 mice. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:21512289 |
| Tang H et al. | [Analysis of fatty acids in leaves of Loropetalum chinense and L. chinense var. rubrum by GC-MS]. | 2011 | Zhong Yao Cai | pmid:22372144 |
| Wong WT et al. | Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta. | 2011 | Nutr Metab Cardiovasc Dis | pmid:20005687 |
| Lin X et al. | Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs. | 2011 | J. Nutr. Biochem. | pmid:21216581 |
| Rosberg-Cody E et al. | Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice. | 2011 | Microbiology (Reading, Engl.) | pmid:21178166 |
| Tuo Y et al. | Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways. | 2011 | Endocrine | pmid:21161439 |
| Hamberg M | Stereochemistry of hydrogen removal during oxygenation of linoleic acid by singlet oxygen and synthesis of 11(S)-deuterium-labeled linoleic acid. | 2011 | Lipids | pmid:21161604 |