Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hoelgaard A and Møllgaard B | Permeation of linoleic acid through skin in vitro. | 1982 | J. Pharm. Pharmacol. | pmid:6127396 |
Letts V et al. | Synthesis and utilization of fatty acids by wild-type and fatty acid auxotrophs of Caulobacter crescentus. | 1982 | J. Bacteriol. | pmid:7107555 |
Enser M and Roberts JL | The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid composition of the diet. | 1982 | Biochem. J. | pmid:6128973 |
Mitranic MM et al. | The effect of linoleic acid and benzyl alcohol on the activity of glycosyltransferases of rat liver Golgi membranes and some soluble glycosyltransferases. | 1982 | Biochim. Biophys. Acta | pmid:6217837 |
Carreau JP et al. | Cholesterol synthesis in the liver, kidneys and brain after injection of uniformly 14C-labeled oleic or linoleic acid to developing rats. | 1982 | Ann. Nutr. Metab. | pmid:6814348 |
Miura S et al. | Lymphatic role in the pathogenesis of fat malabsorption in liver cirrhosis in rats. | 1982 | Dig. Dis. Sci. | pmid:7140488 |
Cuebas D and Schulz H | Evidence for a modified pathway of linoleate degradation. Metabolism of 2,4-decadienoyl coenzyme A. | 1982 | J. Biol. Chem. | pmid:7142199 |
Iritani N and Ikeda Y | Activation of catalase and other enzymes by corn oil intake. | 1982 | J. Nutr. | pmid:7143106 |
Hølmer G et al. | Influence of partially hydrogenated vegetable and marine oils on lipid metabolism in rat liver and heart. | 1982 | Lipids | pmid:7144446 |
Hoffmann P et al. | Alterations in renal and aortic prostaglandin E and F formation correlate with blood pressure dietary linoleate deficiency. | 1982 | Arch Int Pharmacodyn Ther | pmid:7181575 |
Cunnane SC | Differential regulation of essential fatty acid metabolism to the prostaglandins: possible basis for the interaction of zinc and copper in biological systems. | 1982 | Prog. Lipid Res. | pmid:7051042 |
Rosing U et al. | Relative fatty acid composition of serum lecithin in the second half of the normal pregnancy. | 1982 | Gynecol. Obstet. Invest. | pmid:7129232 |
Denning GM et al. | Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells. | 1982 | J. Lipid Res. | pmid:6808070 |
Beaudry GA et al. | Stimulation of deacylation in Madin-Darby canine kidney cells. Specificity of deacylation and prostaglandin production in 12-O-tetradecanoylphorbol-13-acetate-treated cells. | 1982 | J. Biol. Chem. | pmid:6809762 |
Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: I. Design of the study, material and methods. | 1982 | Can J Neurol Sci | pmid:7049340 |
Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: II. Clinical results. | 1982 | Can J Neurol Sci | pmid:7049341 |
Hill EG et al. | Perturbation of the metabolism of essential fatty acids by dietary partially hydrogenated vegetable oil. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6951178 |
Singh SP et al. | Absence of effect of prostaglandins on cholesteryl ester metabolism of 3T3 mouse fibroblasts grown in tissue culture. | 1982 | Atherosclerosis | pmid:6952877 |
Seward RA et al. | Effects of potassium sorbate and other antibotulinal agents on germination and outgrowth of Clostridium botulinum type E spores in microcultures. | 1982 | Appl. Environ. Microbiol. | pmid:6758699 |
Lange LG | Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6955782 |
Hoffmann P et al. | Augmented acute hypotensive effect of dihydralazine and clonidine after linoleic acid rich diet in normotensive conscious rats. | 1982 | Prostaglandins Leukot Med | pmid:6955801 |
Sullivan LM and Mathias MM | Eicosanoid production in rat blood as affected by fasting and dietary fat. | 1982 | Prostaglandins Leukot Med | pmid:6956928 |
Verma SP and Wallach DF | Action of ionizing radiation on lipid-protein interaction. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6896453 |
Singer P et al. | [Clinical aspects of typical changes in carbohydrate and lipid metabolism in essential hypertension]. | 1982 | Z Gesamte Inn Med | pmid:6750938 |
Cherif A | [Linoleic acid synthesis in oleaginous seeds]. | 1981 Sep-Dec | Arch Inst Pasteur Tunis | pmid:7316620 |
Volpe JJ and Obert KA | Coordinate regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A synthase but not 3-hydroxy-3-methylglutaryl coenzyme A reductase in C-6 glia. | 1981 | Arch. Biochem. Biophys. | pmid:6118099 |
Lewis MG et al. | Effect of essential polyunsaturated fatty acid modifications on prostaglandin production by MDCK canine kidney cells. | 1981 | Prostaglandins | pmid:6799988 |
Gavigan SJ and Knight BL | Catabolism of low-density lipoprotein by fibroblasts cultured in medium supplemented with saturated or unsaturated free fatty acids. | 1981 | Biochim. Biophys. Acta | pmid:6271233 |
Knorr A et al. | Cardiostimulating effect of sodium linoleate and its influence on effects of cardiac glycosides. | 1981 | Arch Int Pharmacodyn Ther | pmid:6279044 |
Cheah AM | Effect of long chain unsaturated fatty acids on the calcium transport of sarcoplasmic reticulum. | 1981 | Biochim. Biophys. Acta | pmid:6118177 |
Alberghina M et al. | Axonal transport of phospholipids in rabbit optic pathway. | 1981 | Neurochem. Res. | pmid:7279114 |
Liffmann SM and Lynch RD | Incorporation of [3H]acetate into L-cell lipids. Dependence on method of linoleate administration and timing of the pulse label. | 1981 | Biochim. Biophys. Acta | pmid:7295748 |
Macdonald MC et al. | Dietary linoleic acid and salt-induced hypertension. | 1981 | Can. J. Physiol. Pharmacol. | pmid:7296385 |
Lindström M et al. | Aqueous lipid phases of relevance to intestinal fat digestion and absorption. | 1981 | Lipids | pmid:7300594 |
Cunnane SC and Wahle KW | Zinc deficiency increases the rate of delta 6 desaturation of linoleic acid in rat mammary tissue. | 1981 | Lipids | pmid:7300596 |
Murphy DJ and Stumpf PK | Polyunsaturation systems from higher plants. | 1981 | Meth. Enzymol. | pmid:7311864 |
Rice DA et al. | Reproduction of nutritional degenerative myopathy in the post ruminant calf. | 1981 | Vet. Rec. | pmid:7324363 |
Fernandes J et al. | The effect of a virtually cholesterol-free, high-linoleic-acid vegetarian diet on serum lipoproteins of children with familial hypercholesterolemia (type II-A). | 1981 | Acta Paediatr Scand | pmid:7324917 |
Twaddle ML et al. | Kinetics of appearance of lipoprotein particles in perisinusoidal cisternae of smooth endoplasmic reticulum of isolated rat livers perfused with free fatty acid. | 1981 | Eur. J. Cell Biol. | pmid:7327182 |
Otsuka H et al. | [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. | 1981 | Yakugaku Zasshi | pmid:7338798 |
Dwyer LA and Blomquist GJ | Biosynthesis of linoleic acid in the American cockroach. | 1981 | Prog. Lipid Res. | pmid:7342085 |
Launay M et al. | Control of replication by dietary lipids and namely by linoleic acid in liver and adipose tissue of developing rats. | 1981 | Prog. Lipid Res. | pmid:7342098 |
Houtsmuller AJ et al. | Favorable influences of linoleic acid on the progression of diabetic micro- and macroangiopathy in adult onset diabetes mellitus. | 1981 | Prog. Lipid Res. | pmid:7342100 |
Cunnane SC | Zinc and copper interact antagonistically in the regulation of linoleic acid metabolism. | 1981 | Prog. Lipid Res. | pmid:7342114 |
Lynn WS et al. | Linoleic acid: a specific cytotaxin for macrophages. | 1981 | Prog. Lipid Res. | pmid:7342119 |
Kitada S et al. | Characterization of a lipid mobilizing factor from tumors. | 1981 | Prog. Lipid Res. | pmid:7342133 |
Houtsmuller UM and van der Beek A | Effects of topical application of fatty acids. | 1981 | Prog. Lipid Res. | pmid:6804961 |
Spector AA et al. | Utilization of arachidonic and linoleic acids by cultured human endothelial cells. | 1981 | J. Clin. Invest. | pmid:6793627 |
Kinsella JE et al. | Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatty acid, and prostaglandins: an overview. | 1981 | Am. J. Clin. Nutr. | pmid:6794350 |
Vaddadi KS | The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. | 1981 | Prostaglandins Med | pmid:6269135 |
Andersen BR et al. | The effects of arachidonic and other fatty acids on canine neutrophil metabolism. | 1981 | Prostaglandins | pmid:6795686 |
McDaniel HG et al. | Glucose-insulin-potassium induced alterations in individual plasma free fatty acids in patients with acute myocardial infarction. | 1981 | Am. Heart J. | pmid:6787909 |
Naidoo J | Effect of pH on inhibition of plasmid-carrying cultures of Staphylococcus aureus by lipids. | 1981 | J. Gen. Microbiol. | pmid:7320698 |
Christophersen BO and Norseth J | Arachidonic acid synthesis in isolated liver cells:" effects of (-)-carnitine and of (+)-decanoylcarnitine. | 1981 | FEBS Lett. | pmid:6796433 |
Cunnane SC | Diodoquin and linoleic acid absorption in zinc deficiency. | 1981 | Am. J. Clin. Nutr. | pmid:6792900 |
Nakazawa T et al. | Radiation-induced changes of liposomes and lecithin in non-aqueous media. | 1981 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:6975251 |
Hoffmann P and Förster W | Influence of dietary linoleic acid content on blood pressure regulation in salt-loaded rats (with special reference to the prostaglandin system). | 1981 | Adv. Lipid Res. | pmid:6798829 |
Colca JR and Hazelwood RL | Insulin, pancreatic polypeptide, and glucagon release from the chicken pancreas in vitro: responses to changes in medium glucose and free fatty acid content. | 1981 | Gen. Comp. Endocrinol. | pmid:7037532 |
Schieberle P et al. | A study of oxygen isotope scrambling in the enzymic and non-enzymic oxidation of linoleic acid. | 1981 | Biochim. Biophys. Acta | pmid:6798993 |
Burr GO | The essential fatty acids fifty years ago. | 1981 | Prog. Lipid Res. | pmid:7043474 |
Spector AA et al. | Essential fatty acid availability and prostacyclin production by cultured human endothelial cells. | 1981 | Prog. Lipid Res. | pmid:7043481 |
Agradi E et al. | Dietary linoleic acid, accumulation of arachidonic acid in tissue lipids and production of TXB2 and PGI2 in the cardiovascular system. | 1981 | Prog. Lipid Res. | pmid:7043483 |
Mercuri O and De Tomás ME | Early steps on the in vivo incorporation of [1-14C]linoleic acid into liver lipids of protein deficient pregnant rats. | 1981 | Prog. Lipid Res. | pmid:6804968 |
Kuriki Y | Effects of unsaturated fatty acids on the morphogenesis of an unsaturated fatty acid auxotroph of Escherichia coli. | 1981 | J. Bacteriol. | pmid:7024246 |
Albrecht R et al. | [Induction by lindane of microsomal monoxygenases of the liver in the rat: effects of a 72-hour fast]. | 1981 | Food Cosmet Toxicol | pmid:6167500 |
Alling C et al. | Decreased linoleic acid in serum lecithin after ethanol abuse. | 1980 | Subst Alcohol Actions Misuse | pmid:7302797 |
Prout RE and Odutuga AA | Fatty acid composition of neutral lipids and phospholipids of enamel and dentine from human molars. | 1974 | Arch. Oral Biol. | pmid:12692911 |
Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
NESTEL PJ | METABOLISM OF LINOLEATE AND PALMITATE IN PATIENTS WITH HYPERTRIGLYCERIDEMIA AND HEART DISEASE. | 1965 | Metab. Clin. Exp. | pmid:14252339 |
CHRISTAKIS GJ et al. | EFFECT OF A SERUM CHOLESTEROL-LOWERING DIET ON COMPOSITION OF DEPOT FAT IN MAN. | 1965 | Am. J. Clin. Nutr. | pmid:14253897 |
ZUKEL MC | FAT-CONTROLLED DIETS. | 1965 | Am. J. Clin. Nutr. | pmid:14253901 |
DAYTON S et al. | CAN CHANGES IN THE AMERICAN DIET PREVENT CORONARY HEART DISEASE? | 1965 | J Am Diet Assoc | pmid:14256210 |
MARION JE | EFFECT OF AGE AND DIETARY FAT ON THE LIPIDS OF CHICKEN MUSCLE. | 1965 | J. Nutr. | pmid:14257000 |
PRIVETT OS et al. | INFLUENCE OF DIETARY FAT ON TRIGLYCERIDE STRUCTURE IN THE RAT. | 1965 | J. Nutr. | pmid:14259460 |
DATEY KK et al. | ETHYL LINOLEATE IN EXPERIMENTAL ATHEROGENESIS. | 1965 | J Assoc Physicians India | pmid:14263401 |
STEIN O and STEIN Y | FATTY ACID METABOLISM BY IN VIVO LABELED ADIPOSE TISSUE IN ESSENTIAL FATTY ACID DEFICIENT RATS. | 1965 | Proc. Soc. Exp. Biol. Med. | pmid:14264515 |
YAMAMOTO A et al. | INFLUENCE OF DIETARY FATTY ACIDS ON PHOSPHOLIPID FATTY ACID COMPOSITION IN SUBCELLULAR PARTICLES OF RAT LIVER. | 1965 | J. Lipid Res. | pmid:14330770 |
CAMPBELL AM et al. | SERUM LIPIDS OF MEN FED DIETS DIFFERING IN PROTEIN QUALITY AND LINOLEIC ACID CONTENT. | 1965 | Am. J. Clin. Nutr. | pmid:14332349 |
KOKATNUR MG et al. | A RAPID METHOD FOR THE PREPARATION OF PEROXIDES FROM AUTOXIDIZED METHYL ESTERS OF FATTY ACIDS. | 1965 | Anal. Biochem. | pmid:14340025 |
SGOUTAS D et al. | RADIOHOMOGENEITY OF H3- AND C14-LABELED LINOLEIC ACID IN VIVO. | 1965 | J. Lipid Res. | pmid:14343270 |
HARRIS RV and JAMES AT | CONVERSION OF OLEIC ACID INTO LINOLEIC ACID BY A SUBCELLULAR SYSTEM OF CHLORELLA VULGARIS. | 1965 | Biochem. J. | pmid:14346083 |
ALLMANN DW and GIBSON DM | FATTY ACID SYNTHESIS DURING EARLY LINOLEIC ACID DEFICIENCY IN THE MOUSE. | 1965 | J. Lipid Res. | pmid:14280473 |
ALLMANN DW et al. | FATTY ACID SYNTHESIS DURING FAT-FREE REFEEDING OF STARVED RATS. | 1965 | J. Lipid Res. | pmid:14280474 |
STOFFEL W and WIESE H | [THE BIOSYNTHESIS OF OLEIC-, LINOLEIC- AND GAMMA-LINOLENIC ACID IN PHYCOMYCES BLAKESLEEANUS]. | 1965 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:14309053 |
SHAW R | THE OCCURRENCE OF GAMMA-LINOLENIC ACID IN FUNGI. | 1965 | Biochim. Biophys. Acta | pmid:14320219 |
WILLS ED | MECHANISMS OF LIPID PEROXIDE FORMATION IN TISSUES. ROLE OF METALS AND HAEMATIN PROTEINS IN THE CATALYSIS OF THE OXIDATION UNSATURATED FATTY ACIDS. | 1965 | Biochim. Biophys. Acta | pmid:14325327 |
KATO M | FATTY ACIDS IN DROSOPHILA MELANOGASTER. I. THE QUALITATIVE ANALYSIS OF UNSATURATED FATTY ACIDS IN DROSOPHILA MELANOGASTER. | 1965 | Can. J. Biochem. | pmid:14325986 |
MEGHAL SK and NATH MC | ACTION OF FATS AND LINOLEIC ACID ON INTESTINAL SYNTHESIS OF THIAMINE IN THIAMINE-DEFICIENT RATS. | 1965 | Br. J. Nutr. | pmid:14290858 |
TANHUANPAEAE E | STUDIES ON THE INFLUENCE OF DIETARY METHYL LINOLEATE ON SWINE TISSUE LIPIDS WITH SPECIAL REFERENCE TO NUTRITIONAL MUSCULAR AND LIVE DYSTROPHY. | 1965 | Acta Vet. Scand. | pmid:14298292 |
GLENN JL and DAM H | INFLUENCE OF DIETARY LIPIDS ON THE FATTY ACID COMPOSITION OF NEUTRAL LIPIDS AND PHOSPHATIDES IN CHICK LIVER AND BILE. | 1965 | J. Nutr. | pmid:14300993 |
KRAUSE RF | LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A. | 1965 | Am. J. Clin. Nutr. | pmid:14301352 |
JAMES AT et al. | THE BIOSYNTHESIS OF RICINOLEIC ACID. | 1965 | Biochem. J. | pmid:14340094 |
SCHWARTZ S et al. | LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION. | 1965 | Am. J. Med. Sci. | pmid:14254823 |
SINGLETON WS | CHARACTERIZED OILS FOR USE IN INTRAVENOUS FAT EMULSIONS. | 1965 | Am. J. Clin. Nutr. | pmid:14262113 |
STEIN AA et al. | FATTY ACID ANALYSIS OF TWO EXPERIMENTAL TRANSMISSIBLE GLIAL TUMORS BY GAS-LIQUID CHROMATOGRAPHY. | 1965 | Cancer Res. | pmid:14264052 |
DUBIN IN et al. | EFFECTS OF ALBUMIN FRACTION AND LINOLEIC ACID ON GROWTH OF MACROPHAGES IN TISSUE CULTURE. | 1965 | J. Natl. Cancer Inst. | pmid:14287281 |
BAKER RW et al. | SERUM CHOLESTEROL LINOLEATE LEVELS IN MULTIPLE SCLEROSIS. | 1965 | J. Neurol. Neurosurg. Psychiatr. | pmid:14347622 |
ANSTALL HB and TRUJILLO JM | DETERMINATION OF FREE FATTY ACIDS IN PLASMA BY A COLORIMETRIC PROCEDURE: AN APPRAISAL OF THE METHOD AND COMPARISON WITH OTHER TECHNICS. | 1965 | Clin. Chem. | pmid:14319230 |
GLENDE EA and CORNATZER WE | FATTY ACID COMPOSITION OF RAT LIVER LIPIDS DURING CHOLINE DEFICIENCY. | 1965 | J. Nutr. | pmid:14302120 |
HOLMES FE | AIR-COOLED EXTRACTORS AND THEIR USE IN DETERMINATION OF CHOLESTEROL. | 1965 | Clin. Chem. | pmid:14243897 |