Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kambayashi Y et al. | Preferential hydrolysis of oxidized phosphatidylcholine in cholesterol-containing phosphatidylcholine liposome by phospholipase A2. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9588178 |
Kwan KY et al. | Inhibitory effect of linoleic acid on chain elongation and desaturation of 18:2 c,t isomers in lactating and neonatal rats. | 1998 | Lipids | pmid:9590629 |
Egashira Y et al. | Dietary linoleic acid alters alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of niacin synthesis from tryptophan, in the process of protein expression in rat liver. | 1998 | J. Nutr. Sci. Vitaminol. | pmid:9591240 |
Dokko RC et al. | Cellular uptake of stearic, oleic, linoleic, and linolenic acid and their effects on synthesis and secretion of lipids in Hep-G2 cells. | 1998 | Int. J. Biochem. Cell Biol. | pmid:9597754 |
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Geetha T et al. | Effect of triterpenes from Crataeva nurvala stem bark on lipid peroxidation in adjuvant induced arthritis in rats. | 1998 | Pharmacol. Res. | pmid:9602466 |
Tsai WS et al. | Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants. | 1998 | J. Gastroenterol. | pmid:9605950 |
Kouba M and Mourot J | Effect of a high linoleic acid diet on delta 9-desaturase activity, lipogenesis and lipid composition of pig subcutaneous adipose tissue. | 1998 Jan-Feb | Reprod. Nutr. Dev. | pmid:9606747 |
Kleinfeld AM et al. | Transport of long-chain native fatty acids across human erythrocyte ghost membranes. | 1998 | Biochemistry | pmid:9609694 |
Das I and Khan NS | Increased arachidonic acid induced platelet chemiluminescence indicates cyclooxygenase overactivity in schizophrenic subjects. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610837 |
Kikuchi S et al. | Modulation of eosinophil chemotactic activities to leukotriene B4 by n-3 polyunsaturated fatty acids. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610849 |
Ohnishi M et al. | Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. | 1998 | Phytochemistry | pmid:9611825 |
Liu KL and Belury MA | Conjugated linoleic acid reduces arachidonic acid content and PGE2 synthesis in murine keratinocytes. | 1998 | Cancer Lett. | pmid:9619853 |
Emken EA et al. | Effect of dietary arachidonic acid on metabolism of deuterated linoleic acid by adult male subjects. | 1998 | Lipids | pmid:9625594 |
Battu S et al. | Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein. | 1998 | Biochim. Biophys. Acta | pmid:9630716 |
Mizushina Y et al. | An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta. | 1998 | Biol. Pharm. Bull. | pmid:9635497 |
Hughes RK et al. | Characterization of authentic recombinant pea-seed lipoxygenases with distinct properties and reaction mechanisms. | 1998 | Biochem. J. | pmid:9639559 |
Iwase H et al. | Formation of keto and hydroxy compounds of linoleic acid in submitochondrial particles of bovine heart. | 1998 | Free Radic. Biol. Med. | pmid:9641268 |
Murthy S et al. | 13-hydroxy octadecadienoic acid (13-HODE) inhibits triacylglycerol-rich lipoprotein secretion by CaCo-2 cells. | 1998 | J. Lipid Res. | pmid:9643357 |
Aarsland A and Wolfe RR | Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. | 1998 | J. Lipid Res. | pmid:9643360 |