Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kovár J | Hybridoma cultivation in defined serum-free media: growth-supporting substances. IV. Lipids and serum albumin. | 1987 | Folia Biol. (Praha) | pmid:3436465 |
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Ishiura S et al. | Effects of linoleic acid and cations on the activity of a novel high-molecular weight protease, ingensin, from human placenta. | 1986 | Int. J. Biochem. | pmid:3530832 |
Izumi Y et al. | Effects of dietary linoleic acid on blood pressure and renal function in subtotally nephrectomized rats. | 1986 | Proc. Soc. Exp. Biol. Med. | pmid:3532127 |
Hoffmann P et al. | Cardiovascular actions of dihydralazine as modified by dietary linoleic acid. | 1986 | Biomed. Biochim. Acta | pmid:3535786 |
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Hoffmann P et al. | Circadian rhythm of eicosanoid formation as affected by dietary linoleate. | 1986 | Prostaglandins Leukot Med | pmid:3547416 |
Bruneau C et al. | Influence of lipid environment on insulin binding in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552053 |
Bruneau C et al. | Modifications of cellular lipids induce insulin resistance in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552054 |
Perez RV et al. | The effect of donor specific transfusions and dietary fatty acids on rat cardiac allograft survival. | 1987 | J. Surg. Res. | pmid:3553741 |
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Clementz T et al. | Membrane potential, lipid regulation and adenylate energy charge in acyl chain modified Acholeplasma laidlawii. | 1987 | Biochim. Biophys. Acta | pmid:3567184 |
Griffin JF et al. | Recognition of cervical neoplasia by the estimation of a free-radical reaction product (octadeca-9,11-dienoic acid) in biopsy material. | 1987 | Clin. Chim. Acta | pmid:3568417 |
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Emken EA et al. | Metabolism of cis-12-octadecenoic acid and trans-9,trans-12-octadecadienoic acid and their influence on lipogenic enzyme activities in mouse liver. | 1987 | Biochim. Biophys. Acta | pmid:3580379 |
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Christophe A et al. | Efficacy of linoleic acid administered rectally as monoglyceride. | 1987 | Lipids | pmid:3600208 |
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Marshall MW et al. | Effects of low fat diets varying in P/S ratio on nutrient intakes, fecal excretion, blood chemistry profiles, and fatty acids of adult men. | 1986 | J Am Coll Nutr | pmid:3734273 |
Parsons HG et al. | Modulation of human erythrocyte shape and fatty acids by diet. | 1986 | Biochim. Biophys. Acta | pmid:3741859 |
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Fusco AC et al. | Schistosoma mansoni: production of cercarial eicosanoids as correlates of penetration and transformation. | 1986 | J. Parasitol. | pmid:3746561 |