Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Biliary Atresia D001656 4 associated lipids
Leptospirosis D007922 2 associated lipids
Cachexia D002100 21 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Ascites D001201 25 associated lipids
Tremor D014202 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Disease D004194 2 associated lipids
Parkinson Disease D010300 53 associated lipids
Keloid D007627 12 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Haataja M et al. Prostaglandin precursors in rheumatoid arthritis. 1982 Jan-Feb J. Rheumatol. pmid:7086783
Eisen EJ et al. Rates of depletion of linoleic acid from fat depots of selected lines of mice differing in growth rate and adiposity. 1982 Lipids pmid:7087689
O'Connell M et al. The interaction of free fatty acids in radioimmunoassays for reverse triiodothyronine. 1982 J. Clin. Endocrinol. Metab. pmid:7096540
Barbeau A Friedreich's disease 1982: etiologic hypotheses a personal analysis. 1982 Can J Neurol Sci pmid:7104891
Yoo TJ et al. Effect of fatty acid modification of cultured hepatoma cells on susceptibility to natural killer cells. 1982 Cancer Res. pmid:7105033
Letts V et al. Synthesis and utilization of fatty acids by wild-type and fatty acid auxotrophs of Caulobacter crescentus. 1982 J. Bacteriol. pmid:7107555
Kelly R Drug treatment in multiple sclerosis. 1982 Physiotherapy pmid:7111474
Smith FB et al. Increased saturated phospholipid in cultured cells grown with linoleic acid. 1982 In Vitro pmid:7118125
Stantcheva IG et al. Metabolic fate of fatty acids in type II cells isolated from adult rat lung. 1982 Lung pmid:7121064
Rosing U et al. Relative fatty acid composition of serum lecithin in the second half of the normal pregnancy. 1982 Gynecol. Obstet. Invest. pmid:7129232
Mogenson GJ and Box BM Physiological effects of varying dietary linoleic acid in spontaneously hypertensive rats. 1982 Ann. Nutr. Metab. pmid:7137945
Adam O et al. Prostaglandin formation in man during intake of different amounts of linoleic acid in formula diets. 1982 Ann. Nutr. Metab. pmid:7137955
Moore CE and Dhopeshwarkar GA Trans fatty acids: transport and positional specificity in rat placental lecithin. 1982 Biol. Neonate pmid:7138987
Miura S et al. Lymphatic role in the pathogenesis of fat malabsorption in liver cirrhosis in rats. 1982 Dig. Dis. Sci. pmid:7140488
Cuebas D and Schulz H Evidence for a modified pathway of linoleate degradation. Metabolism of 2,4-decadienoyl coenzyme A. 1982 J. Biol. Chem. pmid:7142199
Iritani N and Ikeda Y Activation of catalase and other enzymes by corn oil intake. 1982 J. Nutr. pmid:7143106
Hølmer G et al. Influence of partially hydrogenated vegetable and marine oils on lipid metabolism in rat liver and heart. 1982 Lipids pmid:7144446
Hoffmann P et al. Alterations in renal and aortic prostaglandin E and F formation correlate with blood pressure dietary linoleate deficiency. 1982 Arch Int Pharmacodyn Ther pmid:7181575
Alberghina M et al. Axonal transport of phospholipids in rabbit optic pathway. 1981 Neurochem. Res. pmid:7279114
Liffmann SM and Lynch RD Incorporation of [3H]acetate into L-cell lipids. Dependence on method of linoleate administration and timing of the pulse label. 1981 Biochim. Biophys. Acta pmid:7295748
Macdonald MC et al. Dietary linoleic acid and salt-induced hypertension. 1981 Can. J. Physiol. Pharmacol. pmid:7296385
Lindström M et al. Aqueous lipid phases of relevance to intestinal fat digestion and absorption. 1981 Lipids pmid:7300594
Cunnane SC and Wahle KW Zinc deficiency increases the rate of delta 6 desaturation of linoleic acid in rat mammary tissue. 1981 Lipids pmid:7300596
Alling C et al. Decreased linoleic acid in serum lecithin after ethanol abuse. 1980 Subst Alcohol Actions Misuse pmid:7302797
Murphy DJ and Stumpf PK Polyunsaturation systems from higher plants. 1981 Meth. Enzymol. pmid:7311864
Cherif A [Linoleic acid synthesis in oleaginous seeds]. 1981 Sep-Dec Arch Inst Pasteur Tunis pmid:7316620
Naidoo J Effect of pH on inhibition of plasmid-carrying cultures of Staphylococcus aureus by lipids. 1981 J. Gen. Microbiol. pmid:7320698
Rice DA et al. Reproduction of nutritional degenerative myopathy in the post ruminant calf. 1981 Vet. Rec. pmid:7324363
Fernandes J et al. The effect of a virtually cholesterol-free, high-linoleic-acid vegetarian diet on serum lipoproteins of children with familial hypercholesterolemia (type II-A). 1981 Acta Paediatr Scand pmid:7324917
Twaddle ML et al. Kinetics of appearance of lipoprotein particles in perisinusoidal cisternae of smooth endoplasmic reticulum of isolated rat livers perfused with free fatty acid. 1981 Eur. J. Cell Biol. pmid:7327182
Otsuka H et al. [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. 1981 Yakugaku Zasshi pmid:7338798
Dwyer LA and Blomquist GJ Biosynthesis of linoleic acid in the American cockroach. 1981 Prog. Lipid Res. pmid:7342085
Launay M et al. Control of replication by dietary lipids and namely by linoleic acid in liver and adipose tissue of developing rats. 1981 Prog. Lipid Res. pmid:7342098
Houtsmuller AJ et al. Favorable influences of linoleic acid on the progression of diabetic micro- and macroangiopathy in adult onset diabetes mellitus. 1981 Prog. Lipid Res. pmid:7342100
Cunnane SC Zinc and copper interact antagonistically in the regulation of linoleic acid metabolism. 1981 Prog. Lipid Res. pmid:7342114
Lynn WS et al. Linoleic acid: a specific cytotaxin for macrophages. 1981 Prog. Lipid Res. pmid:7342119
Kitada S et al. Characterization of a lipid mobilizing factor from tumors. 1981 Prog. Lipid Res. pmid:7342133
Cho Y and Ziboh VA Nutritional modulation of guinea pig skin hyperproliferation by essential fatty acid deficiency is associated with selective down regulation of protein kinase C-beta. 1995 J. Nutr. pmid:7472653
Al MD et al. Some aspects of neonatal essential fatty acid status are altered by linoleic acid supplementation of women during pregnancy. 1995 J. Nutr. pmid:7472662
Matsui K and Kajiwara T Cucumber cotyledon lipoxygenase oxygenizes trilinolein at the lipid/water interface. 1995 Lipids pmid:7475989
Cunnane SC et al. Synthesis of linoleate and alpha-linolenate by chain elongation in the rat. 1995 Lipids pmid:7475996
Christen MO et al. Use of linoleic acid radiolysis for assay of antioxidant action of anethole dithiolethione. 1995 Meth. Enzymol. pmid:7476369
Noguchi M et al. Effects of eicosapentaenoic and docosahexaenoic acid on cell growth and prostaglandin E and leukotriene B production by a human breast cancer cell line (MDA-MB-231). 1995 Nov-Dec Oncology pmid:7478431
Ramchurren N and Karmali R Effects of gamma-linolenic and dihomo-gamma-linolenic acids on 7,12-dimethylbenz(alpha)anthracene-induced mammary tumors in rats. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7480079
Kerner J et al. Impaired gut lipid absorptive capacity after trauma-hemorrhage and resuscitation. 1995 Am. J. Physiol. pmid:7485605
Iwase H et al. pH dependent alterations of monoepoxides and monochlorohydrins of linoleic acid, and their existence in vivo. 1995 Biochem. Biophys. Res. Commun. pmid:7488065
Rose DP et al. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. 1995 Nutr Cancer pmid:7491296
Johanning GL and Lin TY Unsaturated fatty acid effects on human breast cancer cell adhesion. 1995 Nutr Cancer pmid:7491298
Groscolas R et al. Developing Yoshida sarcoma does not influence the fatty acid composition of adipose tissues in the rat. 1995 Nutr Cancer pmid:7491300
Decsi T et al. Long-chain polyunsaturated fatty acids in children with severe protein-energy malnutrition with and without human immunodeficiency virus-1 infection. 1995 Am. J. Clin. Nutr. pmid:7491893
Bondy SC and Marwah S Stimulation of synaptosomal free radical production by fatty acids: relation to esterification and to degree of unsaturation. 1995 FEBS Lett. pmid:7498480
Campbell FM and Dutta-Roy AK Plasma membrane fatty acid-binding protein (FABPpm) is exclusively located in the maternal facing membranes of the human placenta. 1995 FEBS Lett. pmid:7498505
Teboul L et al. Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells. 1995 J. Biol. Chem. pmid:7499310
Yamamoto A et al. Absorption enhancement of intrapulmonary administered insulin by various absorption enhancers and protease inhibitors in rats. 1994 J. Pharm. Pharmacol. pmid:7515417
McKenzie KE et al. Omega-3 and omega-6 fatty acids and PGE2 stimulate the growth of normal but not tumor mouse mammary epithelial cells: evidence for alterations in the signaling pathways in tumor cells. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7535935
Eling TE et al. Modulation of EGF cell signaling tyrosine phosphorylation by linoleic acid metabolites. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7537437
Shintani T et al. Recognition system for dietary fatty acids in the rat small intestine. 1995 Biosci. Biotechnol. Biochem. pmid:7549092
Pietsch A et al. N-3 but not N-6 fatty acids reduce the expression of the combined adhesion and scavenger receptor CD36 in human monocytic cells. 1995 Cell Biochem. Funct. pmid:7554100
Yurawecz MP et al. Furan fatty acids determined as oxidation products of conjugated octadecadienoic acid. 1995 Lipids pmid:7564913
Nakayama T et al. Visible spectrophotometric assay, purification, and molecular properties of a lipoxygenase from eggplant (Solanum melongena Linne) fruits. 1995 Biochem. Biophys. Res. Commun. pmid:7575511
Glickman MH and Klinman JP Nature of rate-limiting steps in the soybean lipoxygenase-1 reaction. 1995 Biochemistry pmid:7578005
Gieseg SP et al. 7,8 Dihydroneopterin inhibits low density lipoprotein oxidation in vitro. Evidence that this macrophage secreted pteridine is an anti-oxidant. 1995 Free Radic. Res. pmid:7581810
Laryea MD et al. Fatty acid composition of the milk of well-nourished Sudanese women. 1995 Int J Food Sci Nutr pmid:7584158
Jiang WG et al. Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). 1995 Cancer Res. pmid:7585549
Greco AV et al. Free fatty acid analysis in ascitic fluid improves diagnosis in malignant abdominal tumors. 1995 Clin. Chim. Acta pmid:7586583
Berardesca E et al. Acute irritant dermatitis: effect of short-term topical corticoid treatment. 1995 Curr. Probl. Dermatol. pmid:7587340
Rodier M et al. Effects of insulin therapy upon plasma lipid fatty acids and platelet aggregation in NIDDM with secondary failure to oral antidiabetic agents. 1995 Diabetes Res. Clin. Pract. pmid:7587908
Engman L et al. Organotellurium compounds as efficient retarders of lipid peroxidation in methanol. 1995 Free Radic. Biol. Med. pmid:7590393
Tappia PS et al. Influence of unsaturated fatty acids on the production of tumour necrosis factor and interleukin-6 by rat peritoneal macrophages. 1995 Mol. Cell. Biochem. pmid:7596352
Blée E and Schuber F Stereocontrolled hydrolysis of the linoleic acid monoepoxide regioisomers catalyzed by soybean epoxide hydrolase. 1995 Eur. J. Biochem. pmid:7601104
van de Sandt JJ et al. Release of arachidonic and linoleic acid metabolites in skin organ cultures as characteristics of in vitro skin irritancy. 1995 Fundam Appl Toxicol pmid:7601324
Kurushima H et al. Comparison of hypocholesterolemic effects induced by dietary linoleic acid and oleic acid in hamsters. 1995 Atherosclerosis pmid:7605390
Jenkins TC Butylsoyamide protects soybean oil from ruminal biohydrogenation: effects of butylsoyamide on plasma fatty acids and nutrient digestion in sheep. 1995 J. Anim. Sci. pmid:7608016
Pyles LA et al. Plasma antioxidant depletion after cardiopulmonary bypass in operations for congenital heart disease. 1995 J. Thorac. Cardiovasc. Surg. pmid:7609540
Thomas ME et al. Metabolic effects of fatty acid-bearing albumin on a proximal tubule cell line. 1995 Am. J. Physiol. pmid:7611458
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
Norman HA et al. Licorice-derived compounds inhibit linoleic acid (C:18:2 omega 6) desaturation in soybean chloroplasts. 1995 FEBS Lett. pmid:7615067
Camacho M et al. Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. 1995 J. Biol. Chem. pmid:7615528
Kitano M et al. Lack of promoting effects of alpha-linolenic, linoleic or palmitic acid on urinary bladder carcinogenesis in rats. 1995 Jpn. J. Cancer Res. pmid:7622416
Chu S et al. Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7624373
Rudel LL et al. Dietary polyunsaturated fat modifies low-density lipoproteins and reduces atherosclerosis of nonhuman primates with high and low diet responsiveness. 1995 Am. J. Clin. Nutr. pmid:7625361
Gillet B and Doan BT Phase-sensitive two-dimensional experiment on living animals. 1995 J Magn Reson B pmid:7627434
van der Heijdt LM et al. Changes in the iron coordination sphere of Fe(II) lipoxygenase-1 from soybeans upon binding of linoleate or oleate. 1995 Eur. J. Biochem. pmid:7628469
Chen CC and Chen CS Brugia pahangi: effects of melanization on the uptake of nutrients by microfilariae in vitro. 1995 Exp. Parasitol. pmid:7628569
Krugliak M et al. Antimalarial effects of C18 fatty acids on Plasmodium falciparum in culture and on Plasmodium vinckei petteri and Plasmodium yoelii nigeriensis in vivo. 1995 Exp. Parasitol. pmid:7628573
Guo L et al. Preferential formation of the hydroperoxide of linoleic acid in choline glycerophospholipids in human erythrocytes membrane during peroxidation with an azo initiator. 1995 Free Radic. Biol. Med. pmid:7628726
Emmison N et al. Linoleic and linolenic acids are selectively secreted in triacylglycerol by hepatocytes from neonatal rats. 1995 Am. J. Physiol. pmid:7631907
Leichsenring M et al. Polyunsaturated fatty acids in erythrocyte and plasma lipids of children with severe protein-energy malnutrition. 1995 Acta Paediatr. pmid:7633146
Appel MJ and Woutersen RA Effects of dietary fish oil (MaxEPA) on N-nitrosobis(2-oxopropyl)amine (BOP)-induced pancreatic carcinogenesis in hamsters. 1995 Cancer Lett. pmid:7634246
Rao GN et al. Linoleic acid and its metabolites, hydroperoxyoctadecadienoic acids, stimulate c-Fos, c-Jun, and c-Myc mRNA expression, mitogen-activated protein kinase activation, and growth in rat aortic smooth muscle cells. 1995 J. Clin. Invest. pmid:7635978
Laneuville O et al. Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid. 1995 J. Biol. Chem. pmid:7642610
Noguchi M et al. Effects of indomethacin with or without linoleic acid on human breast cancer cells in vitro. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7644559
Tezabwala BU et al. Immunotoxicity of polyunsaturated fatty acids in serum-free medium. 1995 Immunopharmacol Immunotoxicol pmid:7650296
Schønberg S and Krokan HE The inhibitory effect of conjugated dienoic derivatives (CLA) of linoleic acid on the growth of human tumor cell lines is in part due to increased lipid peroxidation. 1995 Jul-Aug Anticancer Res. pmid:7654003
Raederstorff D et al. Polyunsaturated fatty acid metabolism of human skin fibroblasts during cellular aging. 1995 Int J Vitam Nutr Res pmid:7657482
Khan MF et al. Hematopoietic toxicity of linoleic acid anilide: importance of aniline. 1995 Fundam Appl Toxicol pmid:7665006
Mize CE et al. Lipoprotein-cholesterol responses in healthy infants fed defined diets from ages 1 to 12 months: comparison of diets predominant in oleic acid versus linoleic acid, with parallel observations in infants fed a human milk-based diet. 1995 J. Lipid Res. pmid:7665996
Abdel-Fattah G et al. Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. 1995 J. Lipid Res. pmid:7665997
Romon M et al. Comparison between fat intake assessed by a 3-day food record and phospholipid fatty acid composition of red blood cells: results from the Monitoring of Cardiovascular Disease-Lille Study. 1995 Metab. Clin. Exp. pmid:7666786
van Tol A et al. Dietary trans fatty acids increase serum cholesterylester transfer protein activity in man. 1995 Atherosclerosis pmid:7669083