Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Proteinuria D011507 30 associated lipids
Refsum Disease D012035 19 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperplasia D006965 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
CHRISTAKIS GJ et al. EFFECT OF A SERUM CHOLESTEROL-LOWERING DIET ON COMPOSITION OF DEPOT FAT IN MAN. 1965 Am. J. Clin. Nutr. pmid:14253897
ZUKEL MC FAT-CONTROLLED DIETS. 1965 Am. J. Clin. Nutr. pmid:14253901
Higdon JV et al. Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F(2)-isoprostanes. 2000 Am. J. Clin. Nutr. pmid:10966889
Bjerve KS et al. Alpha-linolenic acid deficiency in man: effect of ethyl linolenate on plasma and erythrocyte fatty acid composition and biosynthesis of prostanoids. 1987 Am. J. Clin. Nutr. pmid:3310599
Hennig B et al. Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells. 1996 Am. J. Clin. Nutr. pmid:8602587
Kark JD et al. Adipose tissue n-6 fatty acids and acute myocardial infarction in a population consuming a diet high in polyunsaturated fatty acids. 2003 Am. J. Clin. Nutr. pmid:12663274
Djoussé L et al. Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study. 2003 Am. J. Clin. Nutr. pmid:12663278
Routi T et al. Effects of prospective, randomized cholesterol-lowering dietary intervention and apolipoprotein E phenotype on serum lipoprotein(a) concentrations of infants aged 7-24 mo. 1996 Am. J. Clin. Nutr. pmid:8602597
KRAUSE RF LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A. 1965 Am. J. Clin. Nutr. pmid:14301352
Anderson RL Quantitation of the effects of trans isomers of linoleic acid on the metabolism of linoleic acid. 1982 Am. J. Clin. Nutr. pmid:7081132
Turpeinen AM et al. Bioconversion of vaccenic acid to conjugated linoleic acid in humans. 2002 Am. J. Clin. Nutr. pmid:12197992
Martinelli N et al. FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. 2008 Am. J. Clin. Nutr. pmid:18842780
SCOTT RF et al. FATTY ACIDS OF SERUM AND ADIPOSE TISSUE IN SIX GROUPS EATING NATURAL DIETS CONTAINING 7 TO 40 PER CENT FAT. 1964 Am. J. Clin. Nutr. pmid:14157830
Innis SM and Elias SL Intakes of essential n-6 and n-3 polyunsaturated fatty acids among pregnant Canadian women. 2003 Am. J. Clin. Nutr. pmid:12540410
Vos E and Cunnane SC Alpha-linolenic acid, linoleic acid, coronary artery disease, and overall mortality. 2003 Am. J. Clin. Nutr. pmid:12540417
Gillingham LG et al. Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. 2013 Am. J. Clin. Nutr. pmid:23221573
Anderson GJ and Connor WE On the demonstration of omega-3 essential-fatty-acid deficiency in humans. 1989 Am. J. Clin. Nutr. pmid:2494878
Bradbury KE et al. The serum fatty acids myristic acid and linoleic acid are better predictors of serum cholesterol concentrations when measured as molecular percentages rather than as absolute concentrations. 2010 Am. J. Clin. Nutr. pmid:19955401
Erickson KL Is there a relation between dietary linoleic acid and cancer of the breast, colon, or prostate? 1998 Am. J. Clin. Nutr. pmid:9665090
Zock PL and Katan MB Linoleic acid intake and cancer risk: a review and meta-analysis. 1998 Am. J. Clin. Nutr. pmid:9665108
MACDONALD I and BARRY PJ CHANGES IN THE FATTY ACID PATTERN OF THE ADIPOSE TISSUE OF OBESE SUBJECTS WHILE ON A REDUCING REGIMEN. 1964 Am. J. Clin. Nutr. pmid:14212750
Rudel LL et al. Dietary polyunsaturated fat modifies low-density lipoproteins and reduces atherosclerosis of nonhuman primates with high and low diet responsiveness. 1995 Am. J. Clin. Nutr. pmid:7625361
PINTER KG et al. FAT ABSORPTION STUDIES IN VARIOUS FORMS OF STEATORRHEA. 1964 Am. J. Clin. Nutr. pmid:14220479
Cleland LG et al. Linoleate inhibits EPA incorporation from dietary fish-oil supplements in human subjects. 1992 Am. J. Clin. Nutr. pmid:1310374
Herbel BK et al. Safflower oil consumption does not increase plasma conjugated linoleic acid concentrations in humans. 1998 Am. J. Clin. Nutr. pmid:9459383
Kinsella JE et al. Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatty acid, and prostaglandins: an overview. 1981 Am. J. Clin. Nutr. pmid:6794350
Adam O and Wolfram G Effect of different linoleic acid intakes on prostaglandin biosynthesis and kidney function in man. 1984 Am. J. Clin. Nutr. pmid:6486083
Weaver BJ et al. Dietary canola oil: effect on the accumulation of eicosapentaenoic acid in the alkenylacyl fraction of human platelet ethanolamine phosphoglyceride. 1990 Am. J. Clin. Nutr. pmid:2181858
SINGLETON WS CHARACTERIZED OILS FOR USE IN INTRAVENOUS FAT EMULSIONS. 1965 Am. J. Clin. Nutr. pmid:14262113
Hodgson JM et al. Can linoleic acid contribute to coronary artery disease? 1993 Am. J. Clin. Nutr. pmid:8192728
Truswell AS Can linoleic acid contribute to coronary artery disease? 1994 Am. J. Clin. Nutr. pmid:8198070
Innis SM and Hansen JW Plasma fatty acid responses, metabolic effects, and safety of microalgal and fungal oils rich in arachidonic and docosahexaenoic acids in healthy adults. 1996 Am. J. Clin. Nutr. pmid:8694015
Jones PJ et al. Whole body oxidation of dietary fatty acids: implications for energy utilization. 1985 Am. J. Clin. Nutr. pmid:3933323
Warensjö E et al. Factor analysis of fatty acids in serum lipids as a measure of dietary fat quality in relation to the metabolic syndrome in men. 2006 Am. J. Clin. Nutr. pmid:16895896
Baylin A et al. alpha-Linolenic acid, Delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction. 2007 Am. J. Clin. Nutr. pmid:17284757
Terpstra AH Effect of conjugated linoleic acid on body composition and plasma lipids in humans: an overview of the literature. 2004 Am. J. Clin. Nutr. pmid:14985207
Cunnane SC Diodoquin and linoleic acid absorption in zinc deficiency. 1981 Am. J. Clin. Nutr. pmid:6792900
Friesen RW and Innis SM Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. 2010 Am. J. Clin. Nutr. pmid:19923368
Abbey M et al. Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation. 1993 Am. J. Clin. Nutr. pmid:8438773
Almario RU et al. Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia. 2001 Am. J. Clin. Nutr. pmid:11451720
Makrides M et al. Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants. 1994 Am. J. Clin. Nutr. pmid:7913291
Oosthuizen W et al. Polyunsaturated fatty acid intake is adversely related to liver function in HIV-infected subjects: the THUSA study. 2006 Am. J. Clin. Nutr. pmid:16685065
Cunnane SC et al. Beta-oxidation of linoleate in obese men undergoing weight loss. 2001 Am. J. Clin. Nutr. pmid:11273844
Elias SL and Innis SM Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. 2001 Am. J. Clin. Nutr. pmid:11273857
Merchant AT et al. Intake of n-6 and n-3 fatty acids and fish and risk of community-acquired pneumonia in US men. 2005 Am. J. Clin. Nutr. pmid:16155282
Seidelin KN et al. Percentage distribution of fatty acids in subcutaneous adipose tissue of patients with peptic ulcer disease. 1993 Am. J. Clin. Nutr. pmid:8416668
Larbi A et al. Acute in vivo elevation of intravascular triacylglycerol lipolysis impairs peripheral T cell activation in humans. 2005 Am. J. Clin. Nutr. pmid:16280424
OLSON FE et al. The use of diets containing large amounts of linoleic acid. 1958 Nov-Dec Am. J. Clin. Nutr. pmid:13594895
Nestel PJ et al. Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations. 1998 Am. J. Clin. Nutr. pmid:9846846
Arca M et al. Erythrocyte fatty acid composition and gallstone disease: results of an epidemiological survey. 1987 Am. J. Clin. Nutr. pmid:3604961