| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Koba K et al. | Effects of dietary proteins on linoleic acid desaturation and membrane fluidity in rat liver microsomes. | 1993 | Lipids | pmid:8316055 |
| Hernell O et al. | Does the bile salt-stimulated lipase of human milk have a role in the use of the milk long-chain polyunsaturated fatty acids? | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8315552 |
| Larner JM et al. | The isolation and characterization of estradiol-fatty acid esters in human ovarian follicular fluid. Identification of an endogenous long-lived and potent family of estrogens. | 1993 | J. Biol. Chem. | pmid:8314757 |
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| Yamaguchi Y et al. | Enhancement of aortic cholesterol deposition by dietary linoleic acid in cholesterol-fed mice: an animal model for primary screening of antiatherosclerotic agents. | 1993 | J Pharmacol Toxicol Methods | pmid:8305719 |
| Marcelo CL and Dunham WR | Fatty acid metabolism studies of human epidermal cell cultures. | 1993 | J. Lipid Res. | pmid:8301228 |
| Ramasamy S et al. | Proteoglycans and endothelial barrier function: effect of linoleic acid exposure to porcine pulmonary artery endothelial cells. | 1993 | Atherosclerosis | pmid:8292102 |
| Li Y et al. | Chemical and alpha-chymotrypsin-mediated proteolytic degradation of insulin in bile salt-unsaturated fatty acid mixed micellar systems. | 1993 | Pharm. Res. | pmid:8290478 |
| Sanjurjo P et al. | Cross-sectional study of percentual changes in total plasmatic fatty acids during pregnancy. | 1993 | Horm. Metab. Res. | pmid:8288163 |
| Sunzeri FJ and Buehring GC | Lipids alter the level and distribution of mouse mammary tumor virus gp52 in vitro. | 1993 | Cancer Lett. | pmid:8287372 |
| Grech ED et al. | Differential free-radical activity after successful and unsuccessful thrombolytic reperfusion in acute myocardial infarction. | 1993 | Coron. Artery Dis. | pmid:8287210 |
| Judd JT and Clevidence BA | Trans fatty acids in human nutrition. | 1993 | Acta Cardiol | pmid:8284978 |
| Saito M and Yamaguchi M | Response of liver microsomal mixed-function oxidases to dietary linoleic acid levels in rats. | 1993 | J. Nutr. Sci. Vitaminol. | pmid:8283320 |
| Hrboticky N et al. | Lovastatin increases arachidonic acid levels and stimulates thromboxane synthesis in human liver and monocytic cell lines. | 1994 | J. Clin. Invest. | pmid:8282787 |
| Murray MJ et al. | Effects of endotoxin on pigs prefed omega-3 vs. omega-6 fatty acid-enriched diets. | 1993 | Am. J. Physiol. | pmid:8279548 |
| Bronstein JC and Bull AW | The correlation between 13-hydroxyoctadecadienoate dehydrogenase (13-HODE dehydrogenase) and intestinal cell differentiation. | 1993 | Prostaglandins | pmid:8278616 |
| Lamb RG et al. | An in vitro model of ethanol-dependent liver cell injury. | 1994 | Hepatology | pmid:8276354 |
| Oulhaj H et al. | Synthesis and distribution of rat Sertoli cell proteoglycans are modulated by linoleate and vitamin E. | 1993 | Biochem. Mol. Biol. Int. | pmid:8275018 |
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| Dehaut F et al. | n-6 polyunsaturated fatty acids increase the neurite length of PC12 cells and embryonic chick motoneurons. | 1993 | Neurosci. Lett. | pmid:8272254 |
| Sullivan JL et al. | Performance of dairy cows fed short staple, Pima, and cracked Pima cottonseed and feed characteristics. | 1993 | J. Dairy Sci. | pmid:8270698 |
| Blee E et al. | Regio- and stereoselectivity of cytochrome P-450 and peroxygenase-dependent formation of cis-12,13-epoxy-9(Z)-octadecenoic acid (vernolic acid) in Euphorbia lagascae. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8267615 |
| Whelan J et al. | Dietary arachidonate enhances tissue arachidonate levels and eicosanoid production in Syrian hamsters. | 1993 | J. Nutr. | pmid:8263613 |
| Viola G et al. | Absorption and distribution of arachidonate in rats receiving lysophospholipids by oral route. | 1993 | J. Lipid Res. | pmid:8263409 |
| Jones AL et al. | Rapid induction of microsomal delta 12(omega 6)-desaturase activity in chilled Acanthamoeba castellanii. | 1993 | Biochem. J. | pmid:8250841 |
| Vargas F et al. | Photodegradation and in vitro phototoxicity of fenofibrate, a photosensitizing anti-hyperlipoproteinemic drug. | 1993 | Photochem. Photobiol. | pmid:8248320 |
| Darmani H et al. | Interferon-gamma-stimulated uptake and turnover of linoleate and arachidonate in macrophages: a possible pathway for hypersensitivity to endotoxin. | 1993 | Cell. Immunol. | pmid:8242772 |
| Tanner JT et al. | Analysis of milk-based infant formula. Phase IV. Iodide, linoleic acid, and vitamins D and K: U.S. Food and Drug Administration-Infant Formula Council: collaborative study. | 1993 Sep-Oct | J AOAC Int | pmid:8241809 |
| Biagi PL et al. | Erythrocyte membrane fatty acid composition in children with atopic dermatitis compared to age-matched controls. | 1993 | Acta Paediatr. | pmid:8241678 |
| Cantrill RC et al. | Variations in temperature and oxygen content do not alter levels of thiobarbiturate reactive material in human breast tumour cells (ZR-75-1) incubated with gamma-linolenic acid. | 1993 Sep-Oct | Anticancer Res. | pmid:8239521 |
| Markovic DZ and Patterson LK | Benzophenone-sensitized lipid peroxidation in linoleate micelles. | 1993 | Photochem. Photobiol. | pmid:8234464 |
| Chan JK et al. | Effect of dietary alpha-linolenic acid and its ratio to linoleic acid on platelet and plasma fatty acids and thrombogenesis. | 1993 | Lipids | pmid:8231657 |
| Daret D et al. | Synthesis of monohydroxylated fatty acids from linoleic acid by rat aortic smooth muscle cells and tissues: influence on prostacyclin production. | 1993 | J. Lipid Res. | pmid:8228632 |
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| Jakobsen K et al. | The biological activity of natural source tocopherols in chickens fed fresh or oxidized fat rich in linoleic acid. | 1993 | Arch Tierernahr | pmid:8215903 |
| de Deckere EA et al. | Hepatic de novo fatty acid synthesis in the rat. | 1993 | Ann. Nutr. Metab. | pmid:8215236 |
| Viscardi RM and Max SR | Unsaturated fatty acid modulation of glucocorticoid receptor binding in L2 cells. | 1993 | Steroids | pmid:8212085 |
| Sakuma S et al. | Effect of 13-hydroperoxyoctadecadienoic acid on 15-hydroxy prostaglandin dehydrogenase activity in rabbit kidney cortex. | 1993 | Prostaglandins | pmid:8210445 |
| Grammatopoulos D et al. | The human myometrial CRH receptor: G proteins and second messengers. | 1994 | Mol. Cell. Endocrinol. | pmid:8206332 |
| Glasgow WC and Eling TE | Structure-activity relationship for potentiation of EGF-dependent mitogenesis by oxygenated metabolites of linoleic acid. | 1994 | Arch. Biochem. Biophys. | pmid:8203891 |
| Yamashiro Y et al. | Effects of ursodeoxycholic acid treatment on essential fatty acid deficiency in patients with biliary atresia. | 1994 | J. Pediatr. Surg. | pmid:8201513 |
| Andrassy RJ et al. | Linoleic acid enhances mitogen response and survival of septic weanling rats. | 1994 | J. Pediatr. Surg. | pmid:8201499 |
| Truswell AS | Can linoleic acid contribute to coronary artery disease? | 1994 | Am. J. Clin. Nutr. | pmid:8198070 |
| Hodgson JM et al. | Can linoleic acid contribute to coronary artery disease? | 1993 | Am. J. Clin. Nutr. | pmid:8192728 |
| Cronan JE and Rock CO | The presence of linoleic acid in Escherichia coli cannot be confirmed. | 1994 | J. Bacteriol. | pmid:8188608 |
| Belluzzi A et al. | Short report: zinc sulphate supplementation corrects abnormal erythrocyte membrane long-chain fatty acid composition in patients with Crohn's disease. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186338 |
| Jakobsen K et al. | Heat production and quantitative oxidation of nutrients by physical activity in pigs. | 1994 | Ann. Nutr. Metab. | pmid:8185282 |
| Avellini L et al. | Linoleic acid passage through the blood-brain barrier and a possible effect of age. | 1994 | Neurochem. Res. | pmid:8183422 |
| Schilstra MJ et al. | Effect of nonionic detergents on lipoxygenase catalysis. | 1994 | Lipids | pmid:8177015 |
| Appel MJ et al. | Effects of dietary linoleic acid on pancreatic carcinogenesis in rats and hamsters. | 1994 | Cancer Res. | pmid:8174115 |