| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Protein-Energy Malnutrition | D011502 | 9 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Coronary Restenosis | D023903 | 10 associated lipids |
| Myocardial Stunning | D017682 | 10 associated lipids |
| Wounds, Penetrating | D014950 | 10 associated lipids |
| Dry Eye Syndromes | D015352 | 10 associated lipids |
| Dermatitis, Seborrheic | D012628 | 10 associated lipids |
| Foreign-Body Reaction | D005549 | 10 associated lipids |
| Gastroesophageal Reflux | D005764 | 10 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hubbard VS and McKenna MC | Absorption of safflower oil and structured lipid preparations in patients with cystic fibrosis. | 1987 | Lipids | pmid:3613873 |
| Marshall LA and Johnston PV | Modulation of tissue prostaglandin synthesizing capacity by increased ratios of dietary alpha-linolenic acid to linoleic acid. | 1982 | Lipids | pmid:6298554 |
| Ruyter B et al. | Influence of temperature and high dietary linoleic acid content on esterification, elongation, and desaturation of PUFA in Atlantic salmon hepatocytes. | 2003 | Lipids | pmid:14577662 |
| Christophe A et al. | Efficacy of linoleic acid administered rectally as monoglyceride. | 1987 | Lipids | pmid:3600208 |
| Pérez-Matute P et al. | Linoleic acid decreases leptin and adiponectin secretion from primary rat adipocytes in the presence of insulin. | 2007 | Lipids | pmid:17647039 |
| Lomascolo A et al. | Study of the delta 12-desaturase system of Lipomyces starkeyi. | 1996 | Lipids | pmid:8900454 |
| van den Boom MA et al. | The influence of a fish oil-enriched diet on the phospholipid fatty acid turnover in the rabbit red cell membrane in vivo. | 1996 | Lipids | pmid:8900458 |
| Yazu K et al. | Mechanism of lower oxidizability of eicosapentaenoate than linoleate in aqueous micelles. | 1996 | Lipids | pmid:8900464 |
| Turnock L et al. | Dietary supplementation with conjugated linoleic acid does not alter the resistance of mice to Listeria monocytogenes infection. | 2001 | Lipids | pmid:11269693 |
| Chuang LT et al. | Effect of conjugated linoleic acid on fungal delta6-desaturase activity in a transformed yeast system. | 2001 | Lipids | pmid:11269694 |
| Precht D et al. | Overestimates of oleic and linoleic acid contents in materials containing trans fatty acids and analyzed with short packed gas chromatographic columns. | 2001 | Lipids | pmid:11269704 |
| Mann NJ et al. | The effect of linoleic, arachidonic and eicosapentaenoic acid supplementation on prostacyclin production in rats. | 1994 | Lipids | pmid:8170284 |
| Wien M et al. | Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. | 2010 | Lipids | pmid:20496049 |
| Higashi K et al. | Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. | 2001 | Lipids | pmid:11214722 |
| Stamey Lanier J et al. | Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. | 2013 | Lipids | pmid:23504269 |
| Gardner HW and Grove MJ | Method to produce 9(S)-hydroperoxides of linoleic and linolenic acids by maize lipoxygenase. | 2001 | Lipids | pmid:11432467 |
| Garg ML et al. | Differential effects of dietary linoleic and alpha-linolenic acid on lipid metabolism in rat tissues. | 1988 | Lipids | pmid:2903427 |
| Hansen HS | Essential fatty acid-supplemented diet decreases renal excretion of immunoreactive arginine-vasopressin in essential fatty acid-deficient rats. | 1982 | Lipids | pmid:7078362 |
| Eisen EJ et al. | Rates of depletion of linoleic acid from fat depots of selected lines of mice differing in growth rate and adiposity. | 1982 | Lipids | pmid:7087689 |
| MartÃnez M and Ballabriga A | Effects of parenteral nutrition with high doses of linoleate on the developing human liver and brain. | 1987 | Lipids | pmid:3106740 |
| Attar-Bashi NM et al. | alpha-linolenic acid and the risk of prostate cancer. | 2004 | Lipids | pmid:15669769 |
| Hämäläinen TI et al. | Stereochemistry of the hydroperoxides formed during autoxidation of CLA methyl ester in the presence of alpha-tocopherol. | 2002 | Lipids | pmid:12120950 |
| Risérus U et al. | CLA and body weight regulation in humans. | 2003 | Lipids | pmid:12733745 |
| Paterson LJ et al. | Positional distribution of CLA in TAG of lamb tissues. | 2002 | Lipids | pmid:12120960 |
| Gruffat D et al. | In vitro comparison of hepatic metabolism of 9cis-11 trans and 10trans-12cis isomers of CLA in the rat. | 2003 | Lipids | pmid:12733748 |
| Banni S et al. | Conjugated linoleic acids (CLA) as precursors of a distinct family of PUFA. | 2004 | Lipids | pmid:15726830 |
| Hølmer G et al. | Influence of partially hydrogenated vegetable and marine oils on lipid metabolism in rat liver and heart. | 1982 | Lipids | pmid:7144446 |
| Osada K et al. | Dietary oxidized cholesterol modulates cholesterol metabolism and linoleic acid desaturation in rats fed high-cholesterol diets. | 1998 | Lipids | pmid:9727605 |
| Harvey KA et al. | Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. | 2012 | Lipids | pmid:22684911 |
| Calder PC | Polyunsaturated fatty acids, inflammation, and immunity. | 2001 | Lipids | pmid:11724453 |
| Makrides M et al. | Perinatal characteristics may influence the outcome of visual acuity. | 2001 | Lipids | pmid:11724461 |
| Cunnane SC | Application of new methods and analytical approaches to research on polyunsaturated fatty acid homeostasis. | 2001 | Lipids | pmid:11724470 |
| Morita M and Tokita M | Hydroxy radical, hexanal, and decadienal generation by autocatalysts in autoxidation of linoleate alone and with eleostearate. | 2008 | Lipids | pmid:18493810 |
| Nelson GJ et al. | Low-fat diets do not lower plasma cholesterol levels in healthy men compared to high-fat diets with similar fatty acid composition at constant caloric intake. | 1995 | Lipids | pmid:8569436 |
| Bahramian N et al. | Fatty acids induce increased granulocyte macrophage-colony stimulating factor secretion through protein kinase C-activation in THP-1 macrophages. | 2004 | Lipids | pmid:15233403 |
| Boeglin WE et al. | Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases. | 2008 | Lipids | pmid:18795358 |
| Koussoroplis AM et al. | From aquatic to terrestrial food webs: decrease of the docosahexaenoic acid/linoleic acid ratio. | 2008 | Lipids | pmid:18335265 |
| Cunnane SC et al. | Magnetic resonance imaging-based balance analysis of linoleate utilization during weight loss in obese humans. | 1999 | Lipids | pmid:10419101 |
| Matsui K and Kajiwara T | Cucumber cotyledon lipoxygenase oxygenizes trilinolein at the lipid/water interface. | 1995 | Lipids | pmid:7475989 |
| Belza K et al. | Carbon recycling from linoleate during severe dietary linoleate deficiency. | 1999 | Lipids | pmid:10419120 |
| Hamberg M | New cyclopentenone fatty acids formed from linoleic and linolenic acids in potato. | 2000 | Lipids | pmid:10858019 |
| Cunnane SC et al. | Synthesis of linoleate and alpha-linolenate by chain elongation in the rat. | 1995 | Lipids | pmid:7475996 |
| Babin F et al. | Suspicion of latent delta5-desaturase and peroxisomal beta-oxidation deficiency in elderly women over 75 years of age. | 1999 | Lipids | pmid:10419136 |
| Kishino T et al. | Changes in liver fatty acid unsaturation after partial hepatectomy in the rat. | 2000 | Lipids | pmid:10858030 |
| Becker W and Bruce A | Retention of linoleic acid in carcass lipids of rats fed different levels of essential fatty acids. | 1986 | Lipids | pmid:3959773 |
| Otsuki T et al. | Two geometrical isomers of linoleic acid: improved total syntheses. | 1986 | Lipids | pmid:3959777 |
| Lokesh BR et al. | The suppression of eicosanoid synthesis by peritoneal macrophages is influenced by the ratio of dietary docosahexaenoic acid to linoleic acid. | 1989 | Lipids | pmid:2528666 |
| Xue C et al. | Differences in lipid characteristics among populations: low-temperature adaptability of ayu, Plecoglossus altivelis. | 2012 | Lipids | pmid:22120618 |
| Jernerén F et al. | Linolenate 9R-dioxygenase and allene oxide synthase activities of Lasiodiplodia theobromae. | 2012 | Lipids | pmid:22048860 |
| Spartano NL et al. | Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. | 2014 | Lipids | pmid:24595513 |
| Gardner HW and Deighton N | Effect of 4-hydroxy-2(E)-nonenal on soybean lipoxygenase-1. | 2001 | Lipids | pmid:11485167 |
| Scislowski V et al. | Dietary linoleic acid-induced hypercholesterolemia and accumulation of very light HDL in steers. | 2004 | Lipids | pmid:15134139 |
| Fukushima M et al. | Comparative hypocholesterolemic effects of six vegetable oils in cholesterol-fed rat. | 1996 | Lipids | pmid:8743054 |
| Fukushima M et al. | Comparative hypocholesterolemic effects of capybara (Hydrochoerus hydrochaeris dabbenei) oil, horse oil, and sardine oil in cholesterol-fed rats. | 1997 | Lipids | pmid:9113627 |
| Lock AL and Bauman DE | Modifying milk fat composition of dairy cows to enhance fatty acids beneficial to human health. | 2004 | Lipids | pmid:15736916 |
| Hagve TA et al. | Norflurazon--an inhibitor of essential fatty acid desaturation in isolated liver cells. | 1985 | Lipids | pmid:4058269 |
| Bin Q et al. | The caspase pathway of linoelaidic acid (9t, 12t-c18:2)-induced apoptosis in human umbilical vein endothelial cells. | 2013 | Lipids | pmid:23065354 |
| Belury MA and Kempa-Steczko A | Conjugated linoleic acid modulates hepatic lipid composition in mice. | 1997 | Lipids | pmid:9075211 |
| Mathias MM and Dupont J | Quantitative relationships between dietary linoleate and prostaglandin (eicosanoid) biosynthesis. | 1985 | Lipids | pmid:4068908 |
| Barclay LR et al. | Photo-initiated peroxidation of lipids in micelles by azaaromatics. | 1997 | Lipids | pmid:9076660 |
| Schneider C et al. | Analysis of lipoxygenase-derived fatty acid hydroperoxides by electrospray ionization tandem mass spectrometry. | 1997 | Lipids | pmid:9076671 |
| Kannan R et al. | Anorexic contribution to increased linoleate mobilization and oxidation in lymphoma-bearing mice. | 1992 | Lipids | pmid:1579055 |
| Koba K et al. | Dietary conjugated linolenic acid in relation to CLA differently modifies body fat mass and serum and liver lipid levels in rats. | 2002 | Lipids | pmid:12030314 |
| Destaillats F and Angers P | Evidence for [1,5] sigmatropic rearrangements of CLA in heated oils. | 2002 | Lipids | pmid:12030325 |
| Trevizan L et al. | Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. | 2012 | Lipids | pmid:22249937 |
| Venkatraman JT et al. | Influence of genotype on diet-induced changes in membrane phosphatidylcholine and phosphatidylethanolamine composition of splenocytes, liver nuclear envelope and liver mitochondria. | 1991 | Lipids | pmid:2046486 |
| Yurawecz MP et al. | Furan fatty acids determined as oxidation products of conjugated octadecadienoic acid. | 1995 | Lipids | pmid:7564913 |
| Ling KY et al. | Mechanisms of linoleic acid uptake by rabbit small intestinal brush border membrane vesicles. | 1989 | Lipids | pmid:2747430 |
| Handelman GJ et al. | Biopsy method for human adipose with vitamin E and lipid measurements. | 1988 | Lipids | pmid:3172989 |
| Chan JK et al. | Effect of dietary alpha-linolenic acid and its ratio to linoleic acid on platelet and plasma fatty acids and thrombogenesis. | 1993 | Lipids | pmid:8231657 |
| Innis SM | Effect of total parenteral nutrition with linoleic acid-rich emulsions on tissue omega 6 and omega 3 fatty acids in the rat. | 1986 | Lipids | pmid:3083173 |
| Tsevegsuren N et al. | Occurrence of a novel cis,cis,cis-octadeca-3,9,12-trienoic (Z,Z,Z-octadeca-3,9,12-trienoic) acid in Chrysanthemum (tanacetum) zawadskii herb. (Compositae) seed oil. | 2003 | Lipids | pmid:12880115 |
| Elabbadi N et al. | Regulation of phosphatidic acid phosphohydrolase 1 by fatty acids. | 2002 | Lipids | pmid:11876265 |
| Alvheim AR et al. | Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. | 2014 | Lipids | pmid:24081493 |
| Corl BA et al. | Trans-7,cis-9 CLA is synthesized endogenously by delta9-desaturase in dairy cows. | 2002 | Lipids | pmid:12216839 |
| Hayman A et al. | High intake, but not low intake, of CLA impairs weight gain in growing mice. | 2002 | Lipids | pmid:12216840 |
| Koba K et al. | Effects of dietary proteins on linoleic acid desaturation and membrane fluidity in rat liver microsomes. | 1993 | Lipids | pmid:8316055 |
| Vázquez CM et al. | Changes in fatty acid desaturation in hepatic and intestinal tissues induced by intestinal resection. | 1993 | Lipids | pmid:8316056 |
| Kruger M et al. | Comparison of the effect of the amount and degree of unsaturation of dietary fat on plasma low density lipoproteins in vervet monkeys. | 1992 | Lipids | pmid:1435092 |
| Rosenblat M et al. | Nitro-Oleic Acid Reduces J774A.1 Macrophage Oxidative Status and Triglyceride Mass: Involvement of Paraoxonase2 and Triglyceride Metabolizing Enzymes. | 2016 | Lipids | pmid:27344666 |
| Schilstra MJ et al. | Effect of nonionic detergents on lipoxygenase catalysis. | 1994 | Lipids | pmid:8177015 |
| Chuang LT et al. | Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase. | 2001 | Lipids | pmid:11768153 |
| Jie MS et al. | Synthesis and nuclear magnetic resonance properties of all geometrical isomers of conjugated linoleic acids. | 1997 | Lipids | pmid:9358429 |
| Miller A et al. | Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells. | 2001 | Lipids | pmid:11768161 |
| Gibson RA et al. | The effect of dietary supplementation with eicosapentaenoic acid on the phospholipid and fatty acid composition of erythrocytes of marmoset. | 1992 | Lipids | pmid:1522760 |
| Ikeda I et al. | Lymphatic absorption of structured glycerolipids containing medium-chain fatty acids and linoleic acid, and their effect on cholesterol absorption in rats. | 1991 | Lipids | pmid:1895884 |
| Chinn KS et al. | Modulation of adjuvant-induced arthritis by dietary arachidonic acid in essential fatty acid-deficient rats. | 1997 | Lipids | pmid:9307941 |
| Venkatraman JT et al. | Effect of dietary fat on diabetes-induced changes in liver microsomal fatty acid composition and glucose-6-phosphatase activity in rats. | 1991 | Lipids | pmid:1652672 |
| Duffin KL et al. | Lipid remodeling in mouse liver and plasma resulting from delta6 fatty acid desaturase inhibition. | 2001 | Lipids | pmid:11795852 |
| Schäfer K et al. | Incorporation of dietary linoleic and conjugated linoleic acids and related effects on eggs of laying hens. | 2001 | Lipids | pmid:11795854 |
| Milne GL and Porter NA | Separation and identification of phospholipid peroxidation products. | 2001 | Lipids | pmid:11795860 |
| Frank H et al. | Monohydroperoxides of linoleic acid in endoplasmic lipids of rats exposed to tetrachloromethane. | 1987 | Lipids | pmid:3431344 |
| Beuerle T and Schwab W | Metabolic profile of linoleic acid in stored apples: formation of 13(R)-hydroxy-9(Z),11(E)-octadecadienoic acid. | 1999 | Lipids | pmid:10443970 |
| Piazza GJ et al. | Isolation of unsaturated diols after oxidation of conjugated linoleic acid with peroxygenase. | 2003 | Lipids | pmid:12784865 |
| Clark RM and Hundrieser KE | A lack of correlation among fatty acids associated with different lipid classes in human milk. | 1993 | Lipids | pmid:8441341 |
| Adlof RO et al. | Changes in conjugated linoleic acid composition within samples obtained from a single source. | 2001 | Lipids | pmid:11337988 |
| de Tomás ME et al. | Metabolic transformation of intracraneally injected [1-14C]linoleic and [1-14C]alpha-linolenic acids in malnourished developing rats. | 1991 | Lipids | pmid:1687158 |
| Li XP et al. | Linolelaidic acid induces a stronger proliferative effect on human umbilical vein smooth muscle cells compared to elaidic acid. | 2013 | Lipids | pmid:23341188 |
| Bandyopadhyay GK et al. | Effect of reproductive states on lipid mobilization and linoleic acid metabolism in mammary glands. | 1995 | Lipids | pmid:7769972 |
| Bandyopadhyay GK et al. | Preferential oxidation of linolenic acid compared to linoleic acid in the liver of catfish (Heteropneustes fossilis and Clarias batrachus). | 1982 | Lipids | pmid:6294434 |