Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Protein-Energy Malnutrition D011502 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Coronary Restenosis D023903 10 associated lipids
Myocardial Stunning D017682 10 associated lipids
Wounds, Penetrating D014950 10 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Wang L et al. [Effects of linoleic acid on intracellular calcium concentration in primarily cultured rat pancreatic β-cells and underlying mechanism]. 2010 Sheng Li Xue Bao pmid:21170499
Bartók T et al. Identification of the first fumonisin mycotoxins with three acyl groups by ESI-ITMS and ESI-TOFMS following RP-HPLC separation: palmitoyl, linoleoyl and oleoyl EFB₁ fumonisin isomers from a solid culture of Fusarium verticillioides. 2010 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21108092
Brito GA et al. Lymphocytes transfer [(14)C]-labeled fatty acids to skeletal muscle in culture; modulation by exercise. 2010 Cell Biochem. Funct. pmid:20517891
Li TL et al. [Study on the chemical constituents of Humulus scandens]. 2010 Zhong Yao Cai pmid:20518305
Czernichow S et al. n-6 Fatty acids and cardiovascular health: a review of the evidence for dietary intake recommendations. 2010 Br. J. Nutr. pmid:20522273
Sorrentino F et al. Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures. 2010 Appl. Microbiol. Biotechnol. pmid:20571794
Tu WC et al. Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20573490
Li GY et al. [Studies on chemistry component and the biological activity of petroleum ether extraction from pre-and post-processed of Cornus officinalis]. 2010 Zhong Yao Cai pmid:20575409
Wei M et al. [Kinetics of bioconversion of linoleic acid to conjugated linoleic acid by permeabilized Lactobacillus acidophilus cells]. 2010 Sheng Wu Gong Cheng Xue Bao pmid:20575439
Caroprese M et al. Flaxseed supplementation improves fatty acid profile of cow milk. 2010 J. Dairy Sci. pmid:20494167
Wien M et al. Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. 2010 Lipids pmid:20496049
Beevi SS et al. Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. 2010 Plant Foods Hum Nutr pmid:20072818
Privé F et al. Temperature and duration of heating of sunflower oil affect ruminal biohydrogenation of linoleic acid in vitro. 2010 J. Dairy Sci. pmid:20105542
Rodríguez AM et al. Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. 2010 Cell. Physiol. Biochem. pmid:20110694
Ivanova L et al. Phomenins and fatty acids from Alternaria infectoria. 2010 Toxicon pmid:20060014
Won JC et al. Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. 2010 Arterioscler. Thromb. Vasc. Biol. pmid:19965780
Dimri M et al. Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells. 2010 Carcinogenesis pmid:19969553
Olveira G et al. Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. 2010 Arch. Bronconeumol. pmid:20045240
Jernerén F et al. Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus. 2010 Biochim. Biophys. Acta pmid:20045744
Paraszkiewicz K et al. Lipid peroxidation in the fungus Curvularia lunata exposed to nickel. 2010 Arch. Microbiol. pmid:20047047
Esmaeili MA and Sonboli A Antioxidant, free radical scavenging activities of Salvia brachyantha and its protective effect against oxidative cardiac cell injury. 2010 Food Chem. Toxicol. pmid:20036303
Kubala L et al. Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. 2010 Free Radic. Biol. Med. pmid:20156554
Li YF et al. Properties of synthetic homoisoflavonoids to reduce oxidants and to protect linoleic acid and dna against oxidation. 2010 J. Agric. Food Chem. pmid:20199083
Jernerén F et al. Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus. 2010 Arch. Biochem. Biophys. pmid:20043865
Kim BS et al. Effect of surfactant on the production of oxygenated unsaturated fatty acids by Bacillus megaterium ALA2. 2010 N Biotechnol pmid:19748603
Joshi SC et al. Antioxidant and antibacterial activities of the leaf essential oils of Himalayan Lauraceae species. 2010 Food Chem. Toxicol. pmid:19766161
Lábaque MC et al. Effect of age and body weight of Greater Rhea (Rhea americana) females on egg number, size and composition. 2010 Br. Poult. Sci. pmid:21161792
Fekete K and Decsi T Long-chain polyunsaturated fatty acids in inborn errors of metabolism. 2010 Nutrients pmid:22254065
Zidi A et al. Pleiotropic effects of the goat prolactin receptor genotype on milk fatty acid composition. 2010 Domest. Anim. Endocrinol. pmid:20399061
Alvaro A et al. Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids. 2010 J. Nutr. Biochem. pmid:19443194
Walloschke B et al. Enrichment of RAW264.7 macrophages with essential 18-carbon fatty acids affects both respiratory burst and production of immune modulating cytokines. 2010 J. Nutr. Biochem. pmid:19447017
Calder PC The American Heart Association advisory on n-6 fatty acids: evidence based or biased evidence? 2010 Br. J. Nutr. pmid:21118616
Ramsden CE et al. n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials. 2010 Br. J. Nutr. pmid:21118617
Lu XF et al. Colorectal cancer cell growth inhibition by linoleic acid is related to fatty acid composition changes. 2010 J Zhejiang Univ Sci B pmid:21121070
Luo H et al. The In vitro antioxidant properties of chinese highland lichens. 2010 J. Microbiol. Biotechnol. pmid:21124057
Olszewska MA et al. Assessment of the content of phenolics and antioxidant action of inflorescences and leaves of selected species from the genus Sorbus sensu stricto. 2010 Molecules pmid:21127463
Della Casa G et al. Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. 2010 Meat Sci. pmid:20374768
Aldai N et al. Double-muscling character influences the trans-18:1 and conjugated linoleic acid profiles in concentrate-fed yearling bulls. 2010 Meat Sci. pmid:20374865
Christensen KB et al. Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma. 2010 Phytother Res pmid:20222152
Chen T et al. Analytical characterization of Hempseed (seed of Cannabis sativa L.) oil from eight regions in China. 2010 J Diet Suppl pmid:22435611
Xiao C et al. Synthesis of methyl-substituted xanthotoxol to clarify prooxidant effect of methyl on radical-induced oxidation of DNA. 2010 Eur J Med Chem pmid:20332056
Bitis L et al. Flavonoids and antioxidant activity of Rosa agrestis leaves. 2010 Nat. Prod. Res. pmid:20397108
Georgiadi A et al. Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress. 2010 Circ. Res. pmid:20378851
Zulkifli RM et al. Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols. 2010 J. Anim. Sci. pmid:20382866
Domínguez T et al. Increasing omega-3 desaturase expression in tomato results in altered aroma profile and enhanced resistance to cold stress. 2010 Plant Physiol. pmid:20382895
Kamkar A et al. The antioxidative effect of Iranian Mentha pulegium extracts and essential oil in sunflower oil. 2010 Food Chem. Toxicol. pmid:20385193
Sarikurkcu C et al. Essential oil composition and antioxidant activity of Thymus longicaulis C. Presl subsp. longicaulis var. longicaulis. 2010 Food Chem. Toxicol. pmid:20385197
Matsuoka T et al. Elevated dietary linoleic acid increases gastric carcinoma cell invasion and metastasis in mice. 2010 Br. J. Cancer pmid:20842125
Lau BY et al. Influence of high-fat diet from differential dietary sources on bone mineral density, bone strength, and bone fatty acid composition in rats. 2010 Appl Physiol Nutr Metab pmid:20962915
Giroix MH et al. Fatty acid pattern of pancreatic islet lipids in Goto-Kakizaki rats. 2010 Endocrine pmid:20963567
Corriher VA et al. Pigeon peas as a supplement for lactating dairy cows fed corn silage-based diets. 2010 J. Dairy Sci. pmid:20965347
Liu S and Han B Differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. 2010 BMC Plant Biol. pmid:20969806
Martin H Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. 2010 Mutat. Res. pmid:20973164
Brodhun F et al. PpoC from Aspergillus nidulans is a fusion protein with only one active haem. 2010 Biochem. J. pmid:19878096
Khiaosa-Ard R et al. Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. 2010 J. Dairy Res. pmid:20482940
Sahoo PK and Behera P Synthesis and biological screening of some novel amidocarbamate derivatives of ketoprofen. 2010 Eur J Med Chem pmid:20434240
Campoy C et al. [Update of knowledge, recommendations and full consensus about the role of long chain polyunsaturated fatty acids in pregnancy, lactating period and first year of life.Asociación Española de Pediatría. Sociedad Española de Ginecología y Obstetricia. Sociedad Española de Nutrición Comunitaria. Academia Española deNutrición y Ciencias de la Alimentación]. 2010 Med Clin (Barc) pmid:20434734
Goicoechea E and Guillen MD Analysis of hydroperoxides, aldehydes and epoxides by 1H nuclear magnetic resonance in sunflower oil oxidized at 70 and 100 degrees C. 2010 J. Agric. Food Chem. pmid:20438132
Zurabashvili DZ et al. [The effect of toxic components in tobacco smoke on the fatty acid profile of dental pulp]. 2010 Georgian Med News pmid:20413813
Cannata S et al. Effect of visual marbling on sensory properties and quality traits of pork loin. 2010 Meat Sci. pmid:20416803
Macouzet M et al. Genetic and functional aspects of linoleate isomerase in Lactobacillus acidophilus. 2010 Appl. Microbiol. Biotechnol. pmid:20461509
McKay DL et al. Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study. 2010 Nutr J pmid:20462428
Zovko Koncić M et al. Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. 2010 Aug-Sep Food Chem. Toxicol. pmid:20488218
Hajlaoui H et al. Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. 2010 Aug-Sep Food Chem. Toxicol. pmid:20488223
NaÄ­dina VP et al. [Changes in lipid composition of human plasma and erythrocyte membranes due to sodium hydroxybutyrate and normobaric hyperoxia during bed rest]. 2010 Jan-Feb Aviakosm Ekolog Med pmid:20804001
McCusker MM and Grant-Kels JM Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. 2010 Jul-Aug Clin. Dermatol. pmid:20620762
Shin D et al. Dietary combination effects of conjugated linoleic acid and flaxseed or fish oil on the concentration of linoleic and arachidonic acid in poultry meat. 2011 Poult. Sci. pmid:21597077
Yepuri G et al. Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA. 2011 Br. J. Nutr. pmid:21281526
Wang L et al. Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells. 2011 J. Endocrinol. pmid:21565851
Royan M et al. Effects of conjugated linoleic acid, fish oil and soybean oil on PPARs (α & γ) mRNA expression in broiler chickens and their relation to body fat deposits. 2011 Int J Mol Sci pmid:22272093
P Wrobel T et al. Imaging of lipids in atherosclerotic lesion in aorta from ApoE/LDLR-/- mice by FT-IR spectroscopy and Hierarchical Cluster Analysis. 2011 Analyst pmid:22007352
Salleh WM et al. Chemical compositions, antioxidant and antimicrobial activities of essential oils of Piper caninum Blume. 2011 Int J Mol Sci pmid:22174627
Lebold KM et al. Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio). 2011 J. Nutr. pmid:22013196
Nishioka N et al. Linoleic acid enhances angiogenesis through suppression of angiostatin induced by plasminogen activator inhibitor 1. 2011 Br. J. Cancer pmid:22015554
Alimi H et al. Evaluation of antioxidant and antiulcerogenic activities of Opuntia ficus indica f. inermis flowers extract in rats. 2011 Environ. Toxicol. Pharmacol. pmid:22004960
Strandvik B The omega-6/omega-3 ratio is of importance! 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:21945460
Espinosa-Neira R et al. Linoleic acid induces an EMT-like process in mammary epithelial cells MCF10A. 2011 Int. J. Biochem. Cell Biol. pmid:21945809
Končić MZ et al. Antiradical, chelating and antioxidant activities of hydroxamic acids and hydroxyureas. 2011 Molecules pmid:21788931
Ramsden CE et al. All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. 2011 World Rev Nutr Diet pmid:21865817
Okuyama H et al. New Cholesterol Guidelines for Longevity (2010). 2011 World Rev Nutr Diet pmid:21865826
Legrand P et al. Update of French nutritional recommendations for fatty acids. 2011 World Rev Nutr Diet pmid:21865827
Khan AA et al. Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: an in vitro study. 2011 Eur J Med Chem pmid:21868138
Arciniega JC et al. Effects of free fatty acids on meibomian lipid films. 2011 Exp. Eye Res. pmid:21718696
Yang Y et al. Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals. 2011 Free Radic. Res. pmid:21128731
Hubert DJ et al. In vitro hepatoprotective and antioxidant activities of crude extract and isolated compounds from Ficus gnaphalocarpa. 2011 Inflammopharmacology pmid:21088994
Jin G et al. Crude lipoxygenase from pig muscle: partial characterization and interactions of temperature, NaCl and pH on its activity. 2011 Meat Sci. pmid:21093161
Du YZ et al. Linoleic acid-grafted chitosan oligosaccharide micelles for intracellular drug delivery and reverse drug resistance of tumor cells. 2011 Int. J. Biol. Macromol. pmid:21093477
Tuei VC et al. Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. 2011 Life Sci. pmid:21396379
Mihaljević B et al. Linoleic acid peroxidation vs. isomerization: a biomimetic model of free radical reactivity in the presence of thiols. 2011 Org. Biomol. Chem. pmid:21442126
Blum JL et al. Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria. 2011 Toxicol In Vitro pmid:21443943
Conforti F et al. Correlation between environmental factors, chemical composition, and antioxidative properties of caper species growing wild in Calabria (South Italy). 2011 Chem. Biodivers. pmid:21404435
Serratosa MP et al. Changes in hydrophilic and lipophilic antioxidant activity in relation to their phenolic composition during the chamber drying of red grapes at a controlled temperature. 2011 J. Agric. Food Chem. pmid:21319807
Parra-Cabrera S et al. Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women. 2011 Matern Child Nutr pmid:21410881
Konkel A and Schunck WH Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. 2011 Biochim. Biophys. Acta pmid:20869469
Liou AP et al. The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin. 2011 Gastroenterology pmid:20955703
Perona JS et al. Olive oil phenols modulate the triacylglycerol molecular species of human very low-density lipoprotein. A randomized, crossover, controlled trial. 2011 Metab. Clin. Exp. pmid:20934731
Mariutto M et al. The elicitation of a systemic resistance by Pseudomonas putida BTP1 in tomato involves the stimulation of two lipoxygenase isoforms. 2011 BMC Plant Biol. pmid:21294872
Pan Z et al. Effects of linoleate on cell viability and lipid metabolic homeostasis in goose primary hepatocytes. 2011 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:21295151
Tsubura A et al. Anticancer effects of garlic and garlic-derived compounds for breast cancer control. 2011 Anticancer Agents Med Chem pmid:21269259
Turk HF et al. Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes. 2011 Int. J. Cancer pmid:20232381