Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Renal Insufficiency, Chronic D051436 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Coronary Restenosis D023903 10 associated lipids
Myocardial Stunning D017682 10 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Wounds, Penetrating D014950 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Chiou TY et al. Extraction of defatted rice bran with subcritical aqueous acetone. 2012 Biosci. Biotechnol. Biochem. pmid:22878207
Ross GR et al. Fatty acid profile of pig meat after probiotic administration. 2012 J. Agric. Food Chem. pmid:22506842
Oliveira RF et al. Biflavonoids from the unripe fruits of Clusia paralicola and their antioxidant activity. 2012 Nat Prod Commun pmid:23413562
Salleh WM et al. Chemical compositions, antioxidant and antimicrobial activity of the essential oils of Piper officinarum (Piperaceae). 2012 Nat Prod Commun pmid:23413576
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Bonacci G et al. Conjugated linoleic acid is a preferential substrate for fatty acid nitration. 2012 J. Biol. Chem. pmid:23144452
Gutla PV et al. Modulation of plant TPC channels by polyunsaturated fatty acids. 2012 J. Exp. Bot. pmid:23105130
Saei-Dehkordi SS et al. Chemical composition and antioxidative activity of Echinophora platyloba DC. essential oil, and its interaction with natural antimicrobials against food-borne pathogens and spoilage organisms. 2012 J. Food Sci. pmid:23106123
Msika O et al. NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells. 2012 Biochim. Biophys. Acta pmid:22564256
Garcia CV et al. Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. 2012 Food Chem pmid:23107675
Ebba S et al. The examination of fatty acid taste with edible strips. 2012 Physiol. Behav. pmid:22521910
Beck JJ et al. Generation of the volatile spiroketals conophthorin and chalcogran by fungal spores on polyunsaturated fatty acids common to almonds and pistachios. 2012 J. Agric. Food Chem. pmid:23153034
Cichosz G and Czeczot H [Milk fat in prophylaxis of cancer diseases]. 2012 Pol. Merkur. Lekarski pmid:23157137
Ozcan MM et al. Characteristics of grape seed and oil from nine Turkish cultivars. 2012 Nat. Prod. Res. pmid:22132714
Moodley R et al. Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. 2012 Anal. Chim. Acta pmid:22632042
Jung CH et al. The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells. 2012 Inflammation pmid:22124782
Ruparel S et al. Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation. 2012 Pain pmid:22633978
Jarret RL and Levy IJ Oil and fatty acid contents in seed of Citrullus lanatus Schrad. 2012 J. Agric. Food Chem. pmid:22540530
Shimomura K et al. Identification of the plant origin of propolis from Jeju Island, Korea, by observation of honeybee behavior and phytochemical analysis. 2012 Biosci. Biotechnol. Biochem. pmid:23132582
Dramane G et al. STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice. 2012 J. Clin. Invest. pmid:22546859
Joshi S et al. Synthesis, antibacterial activity and mode of action of novel linoleic acid-dipeptide-spermidine conjugates. 2012 Org. Biomol. Chem. pmid:22986997
Little JP et al. The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation. 2012 J. Alzheimers Dis. pmid:22045487
Cortie CH and Else PL Dietary docosahexaenoic Acid (22:6) incorporates into cardiolipin at the expense of linoleic Acid (18:2): analysis and potential implications. 2012 Int J Mol Sci pmid:23203135
Li J et al. A chitosan induced 9-lipoxygenase in Adelostemma gracillimum seedlings. 2012 Int J Mol Sci pmid:22312270
Hu ZP et al. Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. 2012 J. Proteome Res. pmid:23078235
Celia C et al. Ethosomes® and transfersomes® containing linoleic acid: physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. 2012 Biomed Microdevices pmid:21960035
Kanter JE et al. Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages. 2012 Biochim. Biophys. Acta pmid:22020260
Poompachee K and Chudapongse N Comparison of the antioxidant and cytotoxic activities of Phyllanthus virgatus and Phyllanthus amarus extracts. 2012 Med Princ Pract pmid:22024634
Yumrutas O et al. Phenolic acid contents, essential oil compositions and antioxidant activities of two varieties of Salvia euphratica from Turkey. 2012 Nat. Prod. Res. pmid:21995274
King NP et al. Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. 2012 BMC Microbiol. pmid:22243671
Tyagi A et al. Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with α-linolenic acid in a rat model of inflammatory bowel disease. 2012 Br. J. Nutr. pmid:22243775
Zhou H et al. Purification and characterization of a novel ~18 kDa antioxidant protein from Ginkgo biloba seeds. 2012 Molecules pmid:23519252
Kurotani K et al. High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. 2012 Nutr Res pmid:23084639
Trevizan L et al. Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. 2012 Lipids pmid:22249937
Georgiadi A et al. Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. 2012 Physiol. Genomics pmid:22274564
Alvheim AR et al. Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. 2012 Obesity (Silver Spring) pmid:22334255
Lee S et al. Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1. 2012 Br. J. Nutr. pmid:21846428
Weiss LA et al. The omega-6 fatty acid linoleic acid is associated with risk of gastroschisis: a novel dietary risk factor. 2012 Am. J. Med. Genet. A pmid:22315197
de Goede J et al. Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20,000 middle-aged men and women in the Netherlands. 2012 Br. J. Nutr. pmid:21816117
Sun X et al. Lipid peroxidation and DNA adduct formation in lymphocytes of premenopausal women: Role of estrogen metabolites and fatty acid intake. 2012 Int. J. Cancer pmid:22322480
Matesanz N et al. Linoleic acid increases monocyte chemotaxis and adhesion to human aortic endothelial cells through protein kinase C- and cyclooxygenase-2-dependent mechanisms. 2012 J. Nutr. Biochem. pmid:21840193
Zhu X et al. Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. 2012 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:22257167
Tanaka R et al. Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. 2012 Adv. Exp. Med. Biol. pmid:22259110
Rodrigues HG et al. Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing. 2012 J. Invest. Dermatol. pmid:21881592
de Batlle J et al. Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD. 2012 J. Nutr. Biochem. pmid:21889886
Koch C et al. Linoleic acid positioning in psi factor producing oxygenase A, a fusion protein with an atypical cytochrome P450 activity. 2012 FEBS J. pmid:21920024
Florence AC et al. Fatty acid profile, trans-octadecenoic, α-linolenic and conjugated linoleic acid contents differing in certified organic and conventional probiotic fermented milks. 2012 Food Chem pmid:22980792
Rasic-Milutinovic Z et al. Lower serum paraoxonase-1 activity is related to linoleic and docosahexanoic fatty acids in type 2 diabetic patients. 2012 Arch. Med. Res. pmid:22222492
Regensburger J et al. Fatty acids and vitamins generate singlet oxygen under UVB irradiation. 2012 Exp. Dermatol. pmid:22229443
Gursoy O et al. The effect of using different probiotic cultures on conjugated linoleic acid (CLA) concentration and fatty acid composition of white pickle cheese. 2012 Int J Food Sci Nutr pmid:22166042
Padilla MN et al. Molecular cloning, functional characterization and transcriptional regulation of a 9-lipoxygenase gene from olive. 2012 Phytochemistry pmid:22169502
Levitan EB et al. α-Linolenic acid, linoleic acid and heart failure in women. 2012 Br. J. Nutr. pmid:22172525
Taârit MB et al. Physiological changes, phenolic content and antioxidant activity of Salvia officinalis L. grown under saline conditions. 2012 J. Sci. Food Agric. pmid:22173568
Figueiredo JA et al. Facile synthesis of oxo-/thioxopyrimidines and tetrazoles C-C linked to sugars as novel non-toxic antioxidant acetylcholinesterase inhibitors. 2012 Carbohydr. Res. pmid:22153708
Byun HJ et al. Lipid ingredients in moisturizers can modulate skin responses to UV in barrier-disrupted human skin in vivo. 2012 J. Dermatol. Sci. pmid:22209282
Burstein S et al. N-Amino acid linoleoyl conjugates: anti-inflammatory activities. 2012 Bioorg. Med. Chem. Lett. pmid:22217875
Cheguru P et al. Adipocyte differentiation-specific gene transcriptional response to C18 unsaturated fatty acids plus insulin. 2012 Pflugers Arch. pmid:22218833
Mormile R et al. Linoleic acid and colorectal cancer cell growth suppression: is the deregulation of mitochondrial survivin the key factor? 2012 Int J Colorectal Dis pmid:22231621
Ramos Morales E et al. Ricinoleic acid inhibits methanogenesis and fatty acid biohydrogenation in ruminal digesta from sheep and in bacterial cultures. 2012 J. Anim. Sci. pmid:22829608
Luévano-Martínez LA et al. A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. 2012 Biochem. J. pmid:22236206
Jorge AT et al. Schinus terebinthifolius Raddi extract and linoleic acid from Passiflora edulis synergistically decrease melanin synthesis in B16 cells and reconstituted epidermis. 2012 Int J Cosmet Sci pmid:22738140
Manzoor M et al. Variation in minerals, phenolics and antioxidant activity of peel and pulp of different varieties of peach (Prunus persica L.) fruit from Pakistan. 2012 Molecules pmid:22728349
Zengin G et al. Composition of essential oil and antioxidant capacity of Centaurea drabifolia Sm. subsp. detonsa (Bornm.) Wagenitz, endemic to Turkey. 2012 Nat. Prod. Res. pmid:21714737
Pestana JM et al. Effect of slaughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers, and nutritional value of intramuscular fat in organic beef. 2012 J. Sci. Food Agric. pmid:22473659
Kuipers RS et al. Gestational age dependent changes of the fetal brain, liver and adipose tissue fatty acid compositions in a population with high fish intakes. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22425685
Zein CO et al. Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism. 2012 Hepatology pmid:22505276
Takahashi T et al. Effect of linoleic acid albumin in a dilution solution and long-term equilibration for freezing of bovine spermatozoa with poor freezability. 2012 Reprod. Domest. Anim. pmid:21635578
Kowalska A et al. Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). 2012 Fish Physiol. Biochem. pmid:21656178
Martínez Marín AL et al. Effects of feeding increasing dietary levels of high oleic or regular sunflower or linseed oil on fatty acid profile of goat milk. 2012 J. Dairy Sci. pmid:22459841
da Silva Acosta D et al. Fullerene and omega-3 and omega-6 fatty acids on fish brain antioxidant status. 2012 Fish Physiol. Biochem. pmid:22451341
Li D et al. Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings. 2012 Int J Nanomedicine pmid:23269869
Wadekar SD et al. Microbial synthesis of rhamnolipids by Pseudomonas aeruginosa (ATCC 10145) on waste frying oil as low cost carbon source. 2012 Prep. Biochem. Biotechnol. pmid:22509850
Ling PR et al. Purified fish oil eliminating linoleic and alpha linolenic acid meets essential fatty acid requirements in rats. 2012 Metab. Clin. Exp. pmid:22512821
Tanigai T et al. Docosahexaenoic acid exerts anti-inflammatory action on human eosinophils through peroxisome proliferator-activated receptor-independent mechanisms. 2012 Int. Arch. Allergy Immunol. pmid:22487606
Romano R et al. Comparison of the frying performance of olive oil and palm superolein. 2012 J. Food Sci. pmid:22490166
Manosroi A et al. Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. 2012 Eur J Pharm Biopharm pmid:22490981
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Smink W et al. Linoleic and α-linolenic acid as precursor and inhibitor for the synthesis of long-chain polyunsaturated fatty acids in liver and brain of growing pigs. 2012 Animal pmid:22436184
Zened A et al. In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows. 2012 Animal pmid:22436225
Liu X et al. Method for screening of bacterial strains biosynthesizing specific conjugated linoleic acid isomers. 2012 J. Agric. Food Chem. pmid:22946615
Steffen BT et al. Obesity modifies the association between plasma phospholipid polyunsaturated fatty acids and markers of inflammation: the Multi-Ethnic Study of Atherosclerosis. 2012 Int J Obes (Lond) pmid:21829163
de Freitas JM et al. Influence of cellular fatty acid composition on the response of Saccharomyces cerevisiae to hydrostatic pressure stress. 2012 FEMS Yeast Res. pmid:22846157
Yu T et al. Activation of oral trigeminal neurons by fatty acids is dependent upon intracellular calcium. 2012 Pflugers Arch. pmid:22644615
de Sousa Ferreira Soares G et al. Spectroscopic and thermooxidative analysis of organic okra oil and seeds from Abelmoschus esculentus. 2012 ScientificWorldJournal pmid:22645459
Wiebe MG et al. Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates. 2012 BMC Biotechnol. pmid:22646156
Angell RJ et al. Fish oil supplementation maintains adequate plasma arachidonate in cats, but similar amounts of vegetable oils lead to dietary arachidonate deficiency from nutrient dilution. 2012 Nutr Res pmid:22652378
Itakura H et al. The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid. 2012 J. Atheroscler. Thromb. pmid:22653220
Das R et al. Preparation of linoleic acid-capped silver nanoparticles and their antimicrobial effect. 2012 IET Nanobiotechnol pmid:22559712
Burrows T et al. A comparative validation of a child food frequency questionnaire using red blood cell membrane fatty acids. 2012 Eur J Clin Nutr pmid:22378224
Vanek VW et al. A.S.P.E.N. position paper: Clinical role for alternative intravenous fat emulsions. 2012 Nutr Clin Pract pmid:22378798
Shin D et al. Effects of dietary combination of n-3 and n-9 fatty acids on the deposition of linoleic and arachidonic acid in broiler chicken meats. 2012 Poult. Sci. pmid:22399741
Billault I et al. Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes. 2012 Anal Bioanal Chem pmid:22349323
Khan R et al. Variation in oil content and fatty acid composition of the seed oil of Acacia species collected from the northwest zone of India. 2012 J. Sci. Food Agric. pmid:22351513
Chen MH and Nelson EB Microbial-induced carbon competition in the spermosphere leads to pathogen and disease suppression in a municipal biosolids compost. 2012 Phytopathology pmid:22352306
Novak EM et al. Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22365109
He M et al. Effect of dietary fat blend enriched in oleic or linoleic acid and monensin supplementation on dairy cattle performance, milk fatty acid profiles, and milk fat depression. 2012 J. Dairy Sci. pmid:22365227
Castro LF et al. Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. 2012 PLoS ONE pmid:22384110
Li KL et al. Characterization of cumulus expansion-inhibiting factor (CEIF) in goat follicles. 2012 Biol. Reprod. pmid:22402961
Dall'Asta C et al. Role of maize hybrids and their chemical composition in Fusarium infection and fumonisin production. 2012 J. Agric. Food Chem. pmid:22409349
Mulligan CM et al. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. 2012 Cardiovasc. Res. pmid:22411972