| MeSH term | MeSH ID | Detail |
|---|---|---|
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Gastrointestinal Hemorrhage | D006471 | 27 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Pseudomonas Infections | D011552 | 25 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| NESTEL PJ | METABOLISM OF LINOLEATE AND PALMITATE IN PATIENTS WITH HYPERTRIGLYCERIDEMIA AND HEART DISEASE. | 1965 | Metab. Clin. Exp. | pmid:14252339 |
| CHRISTAKIS GJ et al. | EFFECT OF A SERUM CHOLESTEROL-LOWERING DIET ON COMPOSITION OF DEPOT FAT IN MAN. | 1965 | Am. J. Clin. Nutr. | pmid:14253897 |
| ZUKEL MC | FAT-CONTROLLED DIETS. | 1965 | Am. J. Clin. Nutr. | pmid:14253901 |
| DAYTON S et al. | CAN CHANGES IN THE AMERICAN DIET PREVENT CORONARY HEART DISEASE? | 1965 | J Am Diet Assoc | pmid:14256210 |
| MARION JE | EFFECT OF AGE AND DIETARY FAT ON THE LIPIDS OF CHICKEN MUSCLE. | 1965 | J. Nutr. | pmid:14257000 |
| GLENN JL and DAM H | INFLUENCE OF DIETARY LIPIDS ON THE FATTY ACID COMPOSITION OF NEUTRAL LIPIDS AND PHOSPHATIDES IN CHICK LIVER AND BILE. | 1965 | J. Nutr. | pmid:14300993 |
| KRAUSE RF | LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A. | 1965 | Am. J. Clin. Nutr. | pmid:14301352 |
| SCHWARTZ S et al. | LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION. | 1965 | Am. J. Med. Sci. | pmid:14254823 |
| SINGLETON WS | CHARACTERIZED OILS FOR USE IN INTRAVENOUS FAT EMULSIONS. | 1965 | Am. J. Clin. Nutr. | pmid:14262113 |
| DUBIN IN et al. | EFFECTS OF ALBUMIN FRACTION AND LINOLEIC ACID ON GROWTH OF MACROPHAGES IN TISSUE CULTURE. | 1965 | J. Natl. Cancer Inst. | pmid:14287281 |
| BAKER RW et al. | SERUM CHOLESTEROL LINOLEATE LEVELS IN MULTIPLE SCLEROSIS. | 1965 | J. Neurol. Neurosurg. Psychiatr. | pmid:14347622 |
| GLENDE EA and CORNATZER WE | FATTY ACID COMPOSITION OF RAT LIVER LIPIDS DURING CHOLINE DEFICIENCY. | 1965 | J. Nutr. | pmid:14302120 |
| Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
| Prout RE and Odutuga AA | Fatty acid composition of neutral lipids and phospholipids of enamel and dentine from human molars. | 1974 | Arch. Oral Biol. | pmid:12692911 |
| Alling C et al. | Decreased linoleic acid in serum lecithin after ethanol abuse. | 1980 | Subst Alcohol Actions Misuse | pmid:7302797 |
| Volpe JJ and Obert KA | Coordinate regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A synthase but not 3-hydroxy-3-methylglutaryl coenzyme A reductase in C-6 glia. | 1981 | Arch. Biochem. Biophys. | pmid:6118099 |
| Lewis MG et al. | Effect of essential polyunsaturated fatty acid modifications on prostaglandin production by MDCK canine kidney cells. | 1981 | Prostaglandins | pmid:6799988 |
| Gavigan SJ and Knight BL | Catabolism of low-density lipoprotein by fibroblasts cultured in medium supplemented with saturated or unsaturated free fatty acids. | 1981 | Biochim. Biophys. Acta | pmid:6271233 |
| Knorr A et al. | Cardiostimulating effect of sodium linoleate and its influence on effects of cardiac glycosides. | 1981 | Arch Int Pharmacodyn Ther | pmid:6279044 |
| Cheah AM | Effect of long chain unsaturated fatty acids on the calcium transport of sarcoplasmic reticulum. | 1981 | Biochim. Biophys. Acta | pmid:6118177 |
| Alberghina M et al. | Axonal transport of phospholipids in rabbit optic pathway. | 1981 | Neurochem. Res. | pmid:7279114 |
| Liffmann SM and Lynch RD | Incorporation of [3H]acetate into L-cell lipids. Dependence on method of linoleate administration and timing of the pulse label. | 1981 | Biochim. Biophys. Acta | pmid:7295748 |
| Macdonald MC et al. | Dietary linoleic acid and salt-induced hypertension. | 1981 | Can. J. Physiol. Pharmacol. | pmid:7296385 |
| Lindström M et al. | Aqueous lipid phases of relevance to intestinal fat digestion and absorption. | 1981 | Lipids | pmid:7300594 |
| Cunnane SC and Wahle KW | Zinc deficiency increases the rate of delta 6 desaturation of linoleic acid in rat mammary tissue. | 1981 | Lipids | pmid:7300596 |
| Murphy DJ and Stumpf PK | Polyunsaturation systems from higher plants. | 1981 | Meth. Enzymol. | pmid:7311864 |
| Rice DA et al. | Reproduction of nutritional degenerative myopathy in the post ruminant calf. | 1981 | Vet. Rec. | pmid:7324363 |
| Fernandes J et al. | The effect of a virtually cholesterol-free, high-linoleic-acid vegetarian diet on serum lipoproteins of children with familial hypercholesterolemia (type II-A). | 1981 | Acta Paediatr Scand | pmid:7324917 |
| Twaddle ML et al. | Kinetics of appearance of lipoprotein particles in perisinusoidal cisternae of smooth endoplasmic reticulum of isolated rat livers perfused with free fatty acid. | 1981 | Eur. J. Cell Biol. | pmid:7327182 |
| Otsuka H et al. | [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. | 1981 | Yakugaku Zasshi | pmid:7338798 |
| Dwyer LA and Blomquist GJ | Biosynthesis of linoleic acid in the American cockroach. | 1981 | Prog. Lipid Res. | pmid:7342085 |
| Launay M et al. | Control of replication by dietary lipids and namely by linoleic acid in liver and adipose tissue of developing rats. | 1981 | Prog. Lipid Res. | pmid:7342098 |
| Houtsmuller AJ et al. | Favorable influences of linoleic acid on the progression of diabetic micro- and macroangiopathy in adult onset diabetes mellitus. | 1981 | Prog. Lipid Res. | pmid:7342100 |
| Cunnane SC | Zinc and copper interact antagonistically in the regulation of linoleic acid metabolism. | 1981 | Prog. Lipid Res. | pmid:7342114 |
| Lynn WS et al. | Linoleic acid: a specific cytotaxin for macrophages. | 1981 | Prog. Lipid Res. | pmid:7342119 |
| Kitada S et al. | Characterization of a lipid mobilizing factor from tumors. | 1981 | Prog. Lipid Res. | pmid:7342133 |
| Houtsmuller UM and van der Beek A | Effects of topical application of fatty acids. | 1981 | Prog. Lipid Res. | pmid:6804961 |
| Spector AA et al. | Utilization of arachidonic and linoleic acids by cultured human endothelial cells. | 1981 | J. Clin. Invest. | pmid:6793627 |
| Kinsella JE et al. | Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatty acid, and prostaglandins: an overview. | 1981 | Am. J. Clin. Nutr. | pmid:6794350 |
| Vaddadi KS | The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. | 1981 | Prostaglandins Med | pmid:6269135 |
| Andersen BR et al. | The effects of arachidonic and other fatty acids on canine neutrophil metabolism. | 1981 | Prostaglandins | pmid:6795686 |
| McDaniel HG et al. | Glucose-insulin-potassium induced alterations in individual plasma free fatty acids in patients with acute myocardial infarction. | 1981 | Am. Heart J. | pmid:6787909 |
| Naidoo J | Effect of pH on inhibition of plasmid-carrying cultures of Staphylococcus aureus by lipids. | 1981 | J. Gen. Microbiol. | pmid:7320698 |
| Christophersen BO and Norseth J | Arachidonic acid synthesis in isolated liver cells:" effects of (-)-carnitine and of (+)-decanoylcarnitine. | 1981 | FEBS Lett. | pmid:6796433 |
| Cunnane SC | Diodoquin and linoleic acid absorption in zinc deficiency. | 1981 | Am. J. Clin. Nutr. | pmid:6792900 |
| Nakazawa T et al. | Radiation-induced changes of liposomes and lecithin in non-aqueous media. | 1981 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:6975251 |
| Hoffmann P and Förster W | Influence of dietary linoleic acid content on blood pressure regulation in salt-loaded rats (with special reference to the prostaglandin system). | 1981 | Adv. Lipid Res. | pmid:6798829 |
| Colca JR and Hazelwood RL | Insulin, pancreatic polypeptide, and glucagon release from the chicken pancreas in vitro: responses to changes in medium glucose and free fatty acid content. | 1981 | Gen. Comp. Endocrinol. | pmid:7037532 |
| Schieberle P et al. | A study of oxygen isotope scrambling in the enzymic and non-enzymic oxidation of linoleic acid. | 1981 | Biochim. Biophys. Acta | pmid:6798993 |
| Burr GO | The essential fatty acids fifty years ago. | 1981 | Prog. Lipid Res. | pmid:7043474 |
| Spector AA et al. | Essential fatty acid availability and prostacyclin production by cultured human endothelial cells. | 1981 | Prog. Lipid Res. | pmid:7043481 |
| Agradi E et al. | Dietary linoleic acid, accumulation of arachidonic acid in tissue lipids and production of TXB2 and PGI2 in the cardiovascular system. | 1981 | Prog. Lipid Res. | pmid:7043483 |
| Mercuri O and De Tomás ME | Early steps on the in vivo incorporation of [1-14C]linoleic acid into liver lipids of protein deficient pregnant rats. | 1981 | Prog. Lipid Res. | pmid:6804968 |
| Kuriki Y | Effects of unsaturated fatty acids on the morphogenesis of an unsaturated fatty acid auxotroph of Escherichia coli. | 1981 | J. Bacteriol. | pmid:7024246 |
| Albrecht R et al. | [Induction by lindane of microsomal monoxygenases of the liver in the rat: effects of a 72-hour fast]. | 1981 | Food Cosmet Toxicol | pmid:6167500 |
| Cherif A | [Linoleic acid synthesis in oleaginous seeds]. | 1981 Sep-Dec | Arch Inst Pasteur Tunis | pmid:7316620 |
| Shechter Y et al. | Evaluation of factors responsible for the inability of insulin to antagonize lipolysis due to high concentrations of catecholamines. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6297490 |
| Marshall LA and Johnston PV | Modulation of tissue prostaglandin synthesizing capacity by increased ratios of dietary alpha-linolenic acid to linoleic acid. | 1982 | Lipids | pmid:6298554 |
| Abbas MK et al. | Ultrastructure and fatty acid composition of fatty acid-modified Morris 7777 hepatoma cells. | 1982 | Cancer Res. | pmid:6812950 |
| Bandyopadhyay GK et al. | Evidence for the inability of the catfish Heteropneustes fossilis & Clarias batrachus, to biosynthesize linoleic & linolenic acids. | 1982 | Indian J. Biochem. Biophys. | pmid:6299932 |
| Hoelgaard A and Møllgaard B | Permeation of linoleic acid through skin in vitro. | 1982 | J. Pharm. Pharmacol. | pmid:6127396 |
| Enser M and Roberts JL | The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid composition of the diet. | 1982 | Biochem. J. | pmid:6128973 |
| Mitranic MM et al. | The effect of linoleic acid and benzyl alcohol on the activity of glycosyltransferases of rat liver Golgi membranes and some soluble glycosyltransferases. | 1982 | Biochim. Biophys. Acta | pmid:6217837 |
| Bonacossa A et al. | Effect of corticosterone, hydrocortisone and prostaglandin fatty acid precursors on the spontaneous motility of the uterus isolated from ovariectomized rats. | 1982 | Prostaglandins | pmid:6278538 |
| Greenspan MD et al. | Studies on the in vivo synthesis of triacylglycerol in mouse liver. | 1982 | Biochim. Biophys. Acta | pmid:7055591 |
| McKerrow JH and Jeong KH | Schistosoma mansoni: cercarial degradation of a radioactively labeled collagen gel. | 1982 | Exp. Parasitol. | pmid:7060706 |
| Stantcheva IG et al. | Metabolic fate of fatty acids in type II cells isolated from adult rat lung. | 1982 | Lung | pmid:7121064 |
| Hansen HS | Essential fatty acid-supplemented diet decreases renal excretion of immunoreactive arginine-vasopressin in essential fatty acid-deficient rats. | 1982 | Lipids | pmid:7078362 |
| Anderson RL | Quantitation of the effects of trans isomers of linoleic acid on the metabolism of linoleic acid. | 1982 | Am. J. Clin. Nutr. | pmid:7081132 |
| Eisen EJ et al. | Rates of depletion of linoleic acid from fat depots of selected lines of mice differing in growth rate and adiposity. | 1982 | Lipids | pmid:7087689 |
| Mogenson GJ and Box BM | Physiological effects of varying dietary linoleic acid in spontaneously hypertensive rats. | 1982 | Ann. Nutr. Metab. | pmid:7137945 |
| Adam O et al. | Prostaglandin formation in man during intake of different amounts of linoleic acid in formula diets. | 1982 | Ann. Nutr. Metab. | pmid:7137955 |
| Moore CE and Dhopeshwarkar GA | Trans fatty acids: transport and positional specificity in rat placental lecithin. | 1982 | Biol. Neonate | pmid:7138987 |
| Miura S et al. | Lymphatic role in the pathogenesis of fat malabsorption in liver cirrhosis in rats. | 1982 | Dig. Dis. Sci. | pmid:7140488 |
| Rosenblum WI | Unsaturated fatty acids and cyclooxygenase inhibitors: effects on pial arterioles. | 1982 | Am. J. Physiol. | pmid:6801999 |
| Cuebas D and Schulz H | Evidence for a modified pathway of linoleate degradation. Metabolism of 2,4-decadienoyl coenzyme A. | 1982 | J. Biol. Chem. | pmid:7142199 |
| Iritani N and Ikeda Y | Activation of catalase and other enzymes by corn oil intake. | 1982 | J. Nutr. | pmid:7143106 |
| Hølmer G et al. | Influence of partially hydrogenated vegetable and marine oils on lipid metabolism in rat liver and heart. | 1982 | Lipids | pmid:7144446 |
| Kaya K and Miura T | Effects of nitrogen dioxide on fatty acid compositions of red cell membranes, sera, and livers in rats. | 1982 | Environ. Res. | pmid:6802637 |
| Hoffmann P et al. | Alterations in renal and aortic prostaglandin E and F formation correlate with blood pressure dietary linoleate deficiency. | 1982 | Arch Int Pharmacodyn Ther | pmid:7181575 |
| Cunnane SC | Differential regulation of essential fatty acid metabolism to the prostaglandins: possible basis for the interaction of zinc and copper in biological systems. | 1982 | Prog. Lipid Res. | pmid:7051042 |
| Shimp JL et al. | The effects of dietary trilinoelaidin on fatty acid and acyl desaturases in rat liver. | 1982 | J. Nutr. | pmid:6802940 |
| Needleman SW et al. | Enrichment of human platelet phospholipids with linoleic acid diminishes thromboxane release. | 1982 | Prostaglandins | pmid:6819602 |
| Claeys M et al. | Characterization of monohydroxylated lipoxygenase metabolites of arachidonic and linoleic acid in rabbit peritoneal tissue. | 1982 | Biochim. Biophys. Acta | pmid:6814493 |
| Simpson HC and Mann JI | Does low dietary intake of linoleic acid predispose to myocardial infarction? | 1982 | Br Med J (Clin Res Ed) | pmid:6814662 |
| Byrne WJ | Intralipid or Liposyn--comparable products? | 1982 | J. Pediatr. Gastroenterol. Nutr. | pmid:6310073 |
| Darfler FJ and Insel PA | Serum-free culture of resting, PHA-stimulated, and transformed lymphoid cells, including hybridomas. | 1982 | Exp. Cell Res. | pmid:7042376 |
| Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: I. Design of the study, material and methods. | 1982 | Can J Neurol Sci | pmid:7049340 |
| Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: II. Clinical results. | 1982 | Can J Neurol Sci | pmid:7049341 |
| Hill EG et al. | Perturbation of the metabolism of essential fatty acids by dietary partially hydrogenated vegetable oil. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6951178 |
| Singh SP et al. | Absence of effect of prostaglandins on cholesteryl ester metabolism of 3T3 mouse fibroblasts grown in tissue culture. | 1982 | Atherosclerosis | pmid:6952877 |
| Lange LG | Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6955782 |
| Hoffmann P et al. | Augmented acute hypotensive effect of dihydralazine and clonidine after linoleic acid rich diet in normotensive conscious rats. | 1982 | Prostaglandins Leukot Med | pmid:6955801 |
| Sullivan LM and Mathias MM | Eicosanoid production in rat blood as affected by fasting and dietary fat. | 1982 | Prostaglandins Leukot Med | pmid:6956928 |
| Rosenthal MD and Whitehurst MC | Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. | 1982 | J. Cell. Physiol. | pmid:6294123 |
| Verma SP and Wallach DF | Action of ionizing radiation on lipid-protein interaction. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6896453 |
| Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: III. Biochemical results. | 1982 | Can J Neurol Sci | pmid:6896672 |
| Singer P et al. | [Clinical aspects of typical changes in carbohydrate and lipid metabolism in essential hypertension]. | 1982 | Z Gesamte Inn Med | pmid:6750938 |
| Brady MS et al. | Formulas and human milk for premature infants: a review and update. | 1982 | J Am Diet Assoc | pmid:6752249 |
| Christophersen BO et al. | Studies on the regulation of arachidonic acid synthesis in isolated rat liver cells. | 1982 | Biochim. Biophys. Acta | pmid:6812639 |