Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Pneumonia, Viral D011024 3 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Precancerous Conditions D011230 48 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Proteinuria D011507 30 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Psoriasis D011565 47 associated lipids
Pulmonary Edema D011654 23 associated lipids
Refractive Errors D012030 1 associated lipids
Refsum Disease D012035 19 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Retinal Degeneration D012162 9 associated lipids
Retinoblastoma D012175 12 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Seizures D012640 87 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Masia A et al. Enrichment with a polyunsaturated fatty acid enhances the survival of Saccharomyces cerevisiae in the presence of tributyltin. 1998 FEMS Microbiol. Lett. pmid:9809434
Hauville C et al. Determination of the yield of radiation-induced peroxidation of sodium linoleate in aqueous monomeric and micellar solutions. 1998 Radiat. Res. pmid:9806603
de Deckere EA et al. Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. 1998 Eur J Clin Nutr pmid:9805223
Cunnane SC et al. Substantial carbon recycling from linoleate into products of de novo lipogenesis occurs in rat liver even under conditions of extreme dietary linoleate deficiency. 1998 J. Lipid Res. pmid:9799813
Bretillon L et al. Desaturation and chain elongation of [1-14C]mono-trans isomers of linoleic and alpha-linolenic acids in perfused rat liver. 1998 J. Lipid Res. pmid:9799809
Turpeinen AM et al. Replacement of dietary saturated by unsaturated fatty acids: effects of platelet protein kinase C activity, urinary content of 2,3-dinor-TXB2 and in vitro platelet aggregation in healthy man. 1998 Thromb. Haemost. pmid:9798986
Schmuck A et al. Fatty acid nutriture in hospitalized elderly women. 1998 J Am Coll Nutr pmid:9791841
Hu ZY et al. cAMP inhibits linoleic acid-induced growth by antagonizing p27(kip1) depletion, but not interfering with the extracellular signal-regulated kinase or AP-1 activities. 1998 Biochim. Biophys. Acta pmid:9784625
Wander RC et al. Influence of long-chain polyunsaturated fatty acids on oxidation of low density lipoprotein. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9774178
Ober MD and Hart CM Attenuation of oxidant-mediated endothelial cell injury with docosahexaenoic acid: the role of intracellular iron. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9774176
Iwamoto S et al. Effects of fatty acids on liver metastasis of ACL-15 rat colon cancer cells. 1998 Nutr Cancer pmid:9770727
Obukowicz MG et al. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. 1998 J. Pharmacol. Exp. Ther. pmid:9765335
Wijewickreme AN and Kitts DD Modulation of metal-induced cytotoxicity by maillard reaction products isolated from coffee brew. 1998 J. Toxicol. Environ. Health Part A pmid:9761134
Spalinger JH et al. Uptake and metabolism of structured triglyceride by Caco-2 cells: reversal of essential fatty acid deficiency. 1998 Am. J. Physiol. pmid:9756493
Benito S et al. Phospholipid fatty acid composition affects enzymatic antioxidant defenses in cultured Swiss 3T3 fibroblasts. 1997 Oct-Dec Redox Rep. pmid:9754326
Kuratko CN and Constante BJ Linoleic acid and tumor necrosis factor-alpha increase manganese superoxide dismutase activity in intestinal cells. 1998 Cancer Lett. pmid:9751273
Ando H et al. Linoleic acid and alpha-linolenic acid lightens ultraviolet-induced hyperpigmentation of the skin. 1998 Arch. Dermatol. Res. pmid:9749992
Kanazawa K and Ashida H Dietary hydroperoxides of linoleic acid decompose to aldehydes in stomach before being absorbed into the body. 1998 Biochim. Biophys. Acta pmid:9748650
Kanazawa K and Ashida H Catabolic fate of dietary trilinoleoylglycerol hydroperoxides in rat gastrointestines. 1998 Biochim. Biophys. Acta pmid:9748647
Berdeaux O et al. In vitro desaturation or elongation of monotrans isomers of linoleic acid by rat liver microsomes. 1998 Mol. Cell. Biochem. pmid:9746207