Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Abbas MK et al. | Ultrastructure and fatty acid composition of fatty acid-modified Morris 7777 hepatoma cells. | 1982 | Cancer Res. | pmid:6812950 |
Enser M and Roberts JL | The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid composition of the diet. | 1982 | Biochem. J. | pmid:6128973 |
Mitranic MM et al. | The effect of linoleic acid and benzyl alcohol on the activity of glycosyltransferases of rat liver Golgi membranes and some soluble glycosyltransferases. | 1982 | Biochim. Biophys. Acta | pmid:6217837 |
Bonacossa A et al. | Effect of corticosterone, hydrocortisone and prostaglandin fatty acid precursors on the spontaneous motility of the uterus isolated from ovariectomized rats. | 1982 | Prostaglandins | pmid:6278538 |
Greenspan MD et al. | Studies on the in vivo synthesis of triacylglycerol in mouse liver. | 1982 | Biochim. Biophys. Acta | pmid:7055591 |
McKerrow JH and Jeong KH | Schistosoma mansoni: cercarial degradation of a radioactively labeled collagen gel. | 1982 | Exp. Parasitol. | pmid:7060706 |
Rosenblum WI | Unsaturated fatty acids and cyclooxygenase inhibitors: effects on pial arterioles. | 1982 | Am. J. Physiol. | pmid:6801999 |
Kaya K and Miura T | Effects of nitrogen dioxide on fatty acid compositions of red cell membranes, sera, and livers in rats. | 1982 | Environ. Res. | pmid:6802637 |
Shimp JL et al. | The effects of dietary trilinoelaidin on fatty acid and acyl desaturases in rat liver. | 1982 | J. Nutr. | pmid:6802940 |
Needleman SW et al. | Enrichment of human platelet phospholipids with linoleic acid diminishes thromboxane release. | 1982 | Prostaglandins | pmid:6819602 |
Hill EG et al. | Perturbation of the metabolism of essential fatty acids by dietary partially hydrogenated vegetable oil. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6951178 |
Singh SP et al. | Absence of effect of prostaglandins on cholesteryl ester metabolism of 3T3 mouse fibroblasts grown in tissue culture. | 1982 | Atherosclerosis | pmid:6952877 |
Lange LG | Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6955782 |
Hoffmann P et al. | Augmented acute hypotensive effect of dihydralazine and clonidine after linoleic acid rich diet in normotensive conscious rats. | 1982 | Prostaglandins Leukot Med | pmid:6955801 |
Sullivan LM and Mathias MM | Eicosanoid production in rat blood as affected by fasting and dietary fat. | 1982 | Prostaglandins Leukot Med | pmid:6956928 |
Rosenthal MD and Whitehurst MC | Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. | 1982 | J. Cell. Physiol. | pmid:6294123 |
Verma SP and Wallach DF | Action of ionizing radiation on lipid-protein interaction. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6896453 |
Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: III. Biochemical results. | 1982 | Can J Neurol Sci | pmid:6896672 |
Singer P et al. | [Clinical aspects of typical changes in carbohydrate and lipid metabolism in essential hypertension]. | 1982 | Z Gesamte Inn Med | pmid:6750938 |
Brady MS et al. | Formulas and human milk for premature infants: a review and update. | 1982 | J Am Diet Assoc | pmid:6752249 |
Christophersen BO et al. | Studies on the regulation of arachidonic acid synthesis in isolated rat liver cells. | 1982 | Biochim. Biophys. Acta | pmid:6812639 |
Haataja M et al. | Prostaglandin precursors in rheumatoid arthritis. | 1982 Jan-Feb | J. Rheumatol. | pmid:7086783 |
Rationale of the diet-heart statement of the American Heart Association. Report of the AHA nutrition committee. | 1982 Mar-Apr | Arteriosclerosis | pmid:7039581 | |
Goodnight SH et al. | Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. | 1982 Mar-Apr | Arteriosclerosis | pmid:7039582 |
Tobian L et al. | Influence of renal prostaglandins and dietary linoleate on hypertension in Dahl S rats. | 1982 May-Jun | Hypertension | pmid:6950924 |
Kaduce TL et al. | Linoleic acid metabolism and prostaglandin production by cultured bovine pulmonary artery endothelial cells. | 1982 Sep-Oct | Arteriosclerosis | pmid:6751307 |
Rosenthal MD and Whitehurst MC | Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6615875 |
Rosenthal MD and Whitehurst MC | Fatty acyl delta 6 desaturation activity of cultured human endothelial cells. Modulation by fetal bovine serum. | 1983 | Biochim. Biophys. Acta | pmid:6297606 |
Oliw EH | Oxygenation of linolenic and linoleic acid to novel vicinal dihydroxy acids by hepatic microsomes of the rabbit. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6301473 |
Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
Linoleic acid, prostaglandin synthesis and chronic renal failure in rats. | 1983 | Nutr. Rev. | pmid:6341898 | |
Yoshida M et al. | Linoleate and fatty acid compositions in the serum lipids of Japanese patients with multiple sclerosis. | 1983 | Acta Neurol. Scand. | pmid:6364685 |
Rustin P et al. | Oxidative interactions between fatty acid peroxy radicals and quinones: possible involvement in cyanide-resistant electron transport in plant mitochondria. | 1983 | Arch. Biochem. Biophys. | pmid:6414377 |
Anggård E | Ethanol, essential fatty acids and prostaglandins. | 1983 | Pharmacol. Biochem. Behav. | pmid:6415673 |
Shechter G and Grossman S | Lipoxygenase from baker's yeast: purification and properties. | 1983 | Int. J. Biochem. | pmid:6416906 |
Campbell TB and Lueking DR | Long-chain fatty acid assimilation By rhodopseudomonas sphaeroides. | 1983 | J. Bacteriol. | pmid:6600450 |
Nemoto N and Takayama S | Effects of unsaturated fatty acids on metabolism of benzo[a]pyrene in an NADPH-fortified rat liver microsomal system. | 1983 | Carcinogenesis | pmid:6311450 |
Horrobin DF and Manku MS | How do polyunsaturated fatty acids lower plasma cholesterol levels? | 1983 | Lipids | pmid:6312241 |
Høy CE et al. | Acyl group distributions in tissue lipids of rats fed evening primrose oil (gamma -linolenic plus linoleic acid) or soybean oil (alpha-linolenic plus linoleic acid). | 1983 | Lipids | pmid:6318009 |
Nicholson T and Omer SA | The application of cumulative sum analysis to the investigation of reticulum motility in ruminant animals. | 1983 | Zentralbl Veterinarmed A | pmid:6318476 |
Kirstein D et al. | Effect of dietary fats on the delta 6- and delta 5-desaturation of fatty acids in rat liver microsomes. | 1983 | Br. J. Nutr. | pmid:6315055 |
Spector AA et al. | Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells. | 1983 | J. Lipid Res. | pmid:6321621 |
Sanders TA | Dietary fat and platelet function. | 1983 | Clin. Sci. | pmid:6309463 |
Goldmacher VS | Immobilization of protein molecules on liposomes. Anchorage by artificially bound unsaturated hydrocarbon tails. | 1983 | Biochem. Pharmacol. | pmid:6189496 |
Gerzer R et al. | Calcium-induced release from platelet membranes of fatty acids that modulate soluble guanylate cyclase. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6134818 |
Frankel EN | Volatile lipid oxidation products. | 1983 | Prog. Lipid Res. | pmid:6306693 |
Gere A et al. | Fatty acid composition of human milk and milk-based formulas in Hungary. | 1983 | Acta Paediatr Hung | pmid:6613576 |
Lloyd D et al. | Adaptive changes in yeast membranes: catabolite repression and oxygen. | 1983 | Biochem. Soc. Trans. | pmid:6617968 |
Eckart J et al. | [Current status of parenteral feeding with fat emulsions. Clinical experiences with infected patients]. | 1983 | Infusionsther Klin Ernahr | pmid:6618658 |
Derambure S et al. | [Platelet aggregation and platelet and plasma fatty acid levels in the child with migraine. Apropos of 40 case reports]. | 1983 | Pediatrie | pmid:6674921 |
Kreutter D et al. | The effect of essential fatty acid deficiency on the stimulation of intestinal calcium transport by 1,25-dihydroxyvitamin D3. | 1983 | J. Biol. Chem. | pmid:6687596 |
Lejman W et al. | Increase in the linoleic acid level in pulmonary surfactant in the rabbit after exposure to high oxygen concentration. | 1983 | Folia Biol. (Krakow) | pmid:6689156 |
Shand JH and Noble RC | The characterization of the linoleic acid desaturation and elongation system in ovine placental tissue. | 1983 | Int. J. Biochem. | pmid:6642054 |
Rapp JH et al. | Lipids of human atherosclerotic plaques and xanthomas: clues to the mechanism of plaque progression. | 1983 | J. Lipid Res. | pmid:6644183 |
Jones R et al. | The analysis of the red cell unsaturated fatty acid test for multiple sclerosis using laser cytopherometry. | 1983 | Phys Med Biol | pmid:6647546 |
MacDonald ML et al. | Role of linoleate as an essential fatty acid for the cat independent of arachidonate synthesis. | 1983 | J. Nutr. | pmid:6408230 |
Gavigan SJ and Knight BL | The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. | 1983 | Biochem. J. | pmid:6651782 |
Jones R et al. | Monitoring changes in the blood of patients with multiple sclerosis. | 1983 | Prog. Brain Res. | pmid:6665128 |
Hoover RL et al. | Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes. | 1983 | J. Cell Biol. | pmid:6223042 |
George AM et al. | Effect of membrane fatty acid changes on the radiation sensitivity of human lymphoid cells. | 1983 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:6601634 |
Greenway DL and Dyke KG | The effect of membrane-bound beta-lactamase on linoleic acid sensitivity in Staphylococcus aureus. | 1983 | J. Gen. Microbiol. | pmid:6605415 |
Pavelka M and Gangl A | Effects of colchicine on the intestinal transport of endogenous lipid. Ultrastructural, biochemical, and radiochemical studies in fasting rats. | 1983 | Gastroenterology | pmid:6822325 |
Breton M et al. | Linoleate incorporation into rat liver membranes phospholipids: effect on plasma membrane ATPase activities and physical properties. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6230079 |
Monnier LH et al. | Plasma lipid fatty acids and platelet function in insulin-dependent diabetic patients. | 1983 | Diabete Metab | pmid:6230269 |
O'Brien PM and Broughton Pipkin F | The effect of essential fatty acid and specific vitamin supplements on vascular sensitivity in the mid-trimester of human pregnancy. | 1983 | Clin Exp Hypertens B | pmid:6872286 |
Purvis JM et al. | Chain elongation-desaturation of linoleic acid during the development of the pig. Implications for the supply of polyenoic fatty acids to the developing brain. | 1983 | Comp. Biochem. Physiol., B | pmid:6872512 |
Weber EJ | Variation in corn (Zea mays L.) for fatty acid compositions of triglycerides and phospholipids. | 1983 | Biochem. Genet. | pmid:6838482 |
Cho BH | Lipid composition and cholesterol esterifying activity in microsomal preparations of porcine coronary arteries and heart tissue. | 1983 | Biochem Med | pmid:6838501 |
Shultz TD and Leklem JE | Selenium status of vegeterians, nonvegetarians, and hormone-dependent cancer subjects. | 1983 | Am. J. Clin. Nutr. | pmid:6849273 |
Charnock JS et al. | Differences in the fatty acid composition of atrial and ventricular phospholipids of rat heart following standard and lipid-supplemented diets. | 1983 | Comp. Biochem. Physiol., B | pmid:6851485 |
Arudi RL et al. | Purification of oleic acid and linoleic acid. | 1983 | J. Lipid Res. | pmid:6854155 |
Kanner J and Kinsella JE | Initiation of lipid peroxidation by a peroxidase/hydrogen peroxide/halide system. | 1983 | Lipids | pmid:6855480 |
Glick JM and Adelman SJ | Established cell lines from rat adipose tissue that secrete lipoprotein lipase. | 1983 | In Vitro | pmid:6862515 |
Ookhtens M and Baker N | Incomplete free fatty acid oxidation by ascites tumor cells under low oxygen tension. | 1983 | Am. J. Physiol. | pmid:6295191 |
Ries W et al. | Selected metabolic results of the Leipzig gerontological longitudinal study. | 1983 Mar-Apr | Z Alternsforsch | pmid:6868654 |
Hoffmann P et al. | Impaired catecholamine inactivation. A prohypertensive stimulus after dietary linoleate deficiency in salt-loaded rats? | 1983 Nov-Dec | Hypertension | pmid:6581124 |
Johnston DV and Marshall LA | Dietary fat, prostaglandins and the immune response. | 1984 | Prog Food Nutr Sci | pmid:6091179 |
Brush MG et al. | Abnormal essential fatty acid levels in plasma of women with premenstrual syndrome. | 1984 | Am. J. Obstet. Gynecol. | pmid:6091462 |
Singer P et al. | Attenuation of high blood pressure by primrose oil, linseed oil and sunflowerseed oil in spontaneously hypertensive rats. | 1984 | Biomed. Biochim. Acta | pmid:6097233 |
Dworkin RH et al. | Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials. | 1984 | Neurology | pmid:6387534 |
Tarozzi G et al. | Fatty acid composition of single brain structures following different alpha linolenate dietary supplementations. | 1984 | Acta Vitaminol. Enzymol. | pmid:6098184 |
Marzouki ZM and Coniglio JG | The effects of hypophysectomy and testosterone treatment on the composition and metabolism of testicular lipids. | 1984 | Lipids | pmid:6482683 |
Adam O and Wolfram G | Effect of different linoleic acid intakes on prostaglandin biosynthesis and kidney function in man. | 1984 | Am. J. Clin. Nutr. | pmid:6486083 |
Pratsch L et al. | Interaction of fusogen substances with the erythrocyte membrane. | 1984 | Biomed. Biochim. Acta | pmid:6487285 |
Jacobs JM and Jacobs NJ | Effect of unsaturated fatty acids on protoporphyrinogen oxidation, a step in heme and chlorophyll synthesis in plant organelles. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6487324 |
Tanizawa H et al. | Natural antioxidants. I. Antioxidative components of tea leaf (Thea sinensis L.). | 1984 | Chem. Pharm. Bull. | pmid:6467480 |
Caponnetto A et al. | [Essential fatty acids for ectodermic organs]. | 1984 | Boll. Soc. Ital. Biol. Sper. | pmid:6518108 |
Caponnetto A et al. | [Alpha-linolenic acid and its metabolic derivatives in the tissues of rats treated with CCl4]. | 1984 | Boll. Soc. Ital. Biol. Sper. | pmid:6518109 |
Yorek MA et al. | Comparative utilization of n-3 polyunsaturated fatty acids by cultured human Y-79 retinoblastoma cells. | 1984 | Biochim. Biophys. Acta | pmid:6089899 |
MacDonald ML et al. | Essential fatty acid requirements of cats: pathology of essential fatty acid deficiency. | 1984 | Am. J. Vet. Res. | pmid:24049889 |
Alao SJ and Balnave D | Growth and carcass composition of broilers fed sunflower oil and olive oil. | 1984 | Br. Poult. Sci. | pmid:6733552 |
Stymne S and Stobart AK | The biosynthesis of triacylglycerols in microsomal preparations of developing cotyledons of sunflower (Helianthus annuus L.). | 1984 | Biochem. J. | pmid:6743281 |
Colard O et al. | 1-Acyl-lysolecithin acyltransferase and synthesis of biliary lecithins in rat liver. | 1984 | Biochimie | pmid:6743697 |
Eyssen H and Verhulst A | Biotransformation of linoleic acid and bile acids by Eubacterium lentum. | 1984 | Appl. Environ. Microbiol. | pmid:6582800 |
Strong AM et al. | Prostaglandin precursors in plasma phospholipids of patients with psoriasis: effects of treatment with coal tar. | 1984 | Prostaglandins Leukot Med | pmid:6588390 |
Merzlyak MN and Kovrizhnih VA | Lipid-phenolic radical adducts as a plausible mechanism of "plant ageing" pigment formation. | 1984 | Gen. Physiol. Biophys. | pmid:6530137 |
Chapkin RS and Ziboh VA | Inability of skin enzyme preparations to biosynthesize arachidonic acid from linoleic acid. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6439197 |
Hagve TA and Christophersen BO | Effect of dietary fats on arachidonic acid and eicosapentaenoic acid biosynthesis and conversion to C22 fatty acids in isolated rat liver cells. | 1984 | Biochim. Biophys. Acta | pmid:6093889 |
Asakawa T et al. | Ca2+-activated, fatty acid-dependent guanylate cyclase in synaptic plasma membranes and its requirement for Ca2+ and Mg-GTP in the activation. | 1984 | Adv. Exp. Med. Biol. | pmid:6149673 |
Wood DA et al. | Adipose tissue and platelet fatty acids and coronary heart disease in Scottish men. | 1984 | Lancet | pmid:6146032 |