Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Cholestasis D002779 23 associated lipids
Olfaction Disorders D000857 17 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Glomerulonephritis D005921 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Ross GR et al. Fatty acid profile of pig meat after probiotic administration. 2012 J. Agric. Food Chem. pmid:22506842
Oliveira RF et al. Biflavonoids from the unripe fruits of Clusia paralicola and their antioxidant activity. 2012 Nat Prod Commun pmid:23413562
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Bonacci G et al. Conjugated linoleic acid is a preferential substrate for fatty acid nitration. 2012 J. Biol. Chem. pmid:23144452
Gutla PV et al. Modulation of plant TPC channels by polyunsaturated fatty acids. 2012 J. Exp. Bot. pmid:23105130
Saei-Dehkordi SS et al. Chemical composition and antioxidative activity of Echinophora platyloba DC. essential oil, and its interaction with natural antimicrobials against food-borne pathogens and spoilage organisms. 2012 J. Food Sci. pmid:23106123
Msika O et al. NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells. 2012 Biochim. Biophys. Acta pmid:22564256
Garcia CV et al. Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. 2012 Food Chem pmid:23107675
Ebba S et al. The examination of fatty acid taste with edible strips. 2012 Physiol. Behav. pmid:22521910
Beck JJ et al. Generation of the volatile spiroketals conophthorin and chalcogran by fungal spores on polyunsaturated fatty acids common to almonds and pistachios. 2012 J. Agric. Food Chem. pmid:23153034
Cichosz G and Czeczot H [Milk fat in prophylaxis of cancer diseases]. 2012 Pol. Merkur. Lekarski pmid:23157137
Jung CH et al. The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells. 2012 Inflammation pmid:22124782
Little JP et al. The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation. 2012 J. Alzheimers Dis. pmid:22045487
Cortie CH and Else PL Dietary docosahexaenoic Acid (22:6) incorporates into cardiolipin at the expense of linoleic Acid (18:2): analysis and potential implications. 2012 Int J Mol Sci pmid:23203135
Li J et al. A chitosan induced 9-lipoxygenase in Adelostemma gracillimum seedlings. 2012 Int J Mol Sci pmid:22312270
Celia C et al. Ethosomes® and transfersomes® containing linoleic acid: physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. 2012 Biomed Microdevices pmid:21960035
Kanter JE et al. Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages. 2012 Biochim. Biophys. Acta pmid:22020260
Poompachee K and Chudapongse N Comparison of the antioxidant and cytotoxic activities of Phyllanthus virgatus and Phyllanthus amarus extracts. 2012 Med Princ Pract pmid:22024634
Yumrutas O et al. Phenolic acid contents, essential oil compositions and antioxidant activities of two varieties of Salvia euphratica from Turkey. 2012 Nat. Prod. Res. pmid:21995274
King NP et al. Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. 2012 BMC Microbiol. pmid:22243671
Tyagi A et al. Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with α-linolenic acid in a rat model of inflammatory bowel disease. 2012 Br. J. Nutr. pmid:22243775
Zhou H et al. Purification and characterization of a novel ~18 kDa antioxidant protein from Ginkgo biloba seeds. 2012 Molecules pmid:23519252
de Goede J et al. Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20,000 middle-aged men and women in the Netherlands. 2012 Br. J. Nutr. pmid:21816117
Matesanz N et al. Linoleic acid increases monocyte chemotaxis and adhesion to human aortic endothelial cells through protein kinase C- and cyclooxygenase-2-dependent mechanisms. 2012 J. Nutr. Biochem. pmid:21840193
Gursoy O et al. The effect of using different probiotic cultures on conjugated linoleic acid (CLA) concentration and fatty acid composition of white pickle cheese. 2012 Int J Food Sci Nutr pmid:22166042
Padilla MN et al. Molecular cloning, functional characterization and transcriptional regulation of a 9-lipoxygenase gene from olive. 2012 Phytochemistry pmid:22169502
Levitan EB et al. α-Linolenic acid, linoleic acid and heart failure in women. 2012 Br. J. Nutr. pmid:22172525
Taârit MB et al. Physiological changes, phenolic content and antioxidant activity of Salvia officinalis L. grown under saline conditions. 2012 J. Sci. Food Agric. pmid:22173568
Figueiredo JA et al. Facile synthesis of oxo-/thioxopyrimidines and tetrazoles C-C linked to sugars as novel non-toxic antioxidant acetylcholinesterase inhibitors. 2012 Carbohydr. Res. pmid:22153708
Byun HJ et al. Lipid ingredients in moisturizers can modulate skin responses to UV in barrier-disrupted human skin in vivo. 2012 J. Dermatol. Sci. pmid:22209282
Ramos Morales E et al. Ricinoleic acid inhibits methanogenesis and fatty acid biohydrogenation in ruminal digesta from sheep and in bacterial cultures. 2012 J. Anim. Sci. pmid:22829608
Kuipers RS et al. Gestational age dependent changes of the fetal brain, liver and adipose tissue fatty acid compositions in a population with high fish intakes. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22425685
Zein CO et al. Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism. 2012 Hepatology pmid:22505276
Martínez Marín AL et al. Effects of feeding increasing dietary levels of high oleic or regular sunflower or linseed oil on fatty acid profile of goat milk. 2012 J. Dairy Sci. pmid:22459841
da Silva Acosta D et al. Fullerene and omega-3 and omega-6 fatty acids on fish brain antioxidant status. 2012 Fish Physiol. Biochem. pmid:22451341
Wadekar SD et al. Microbial synthesis of rhamnolipids by Pseudomonas aeruginosa (ATCC 10145) on waste frying oil as low cost carbon source. 2012 Prep. Biochem. Biotechnol. pmid:22509850
Ling PR et al. Purified fish oil eliminating linoleic and alpha linolenic acid meets essential fatty acid requirements in rats. 2012 Metab. Clin. Exp. pmid:22512821
Tanigai T et al. Docosahexaenoic acid exerts anti-inflammatory action on human eosinophils through peroxisome proliferator-activated receptor-independent mechanisms. 2012 Int. Arch. Allergy Immunol. pmid:22487606
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
de Freitas JM et al. Influence of cellular fatty acid composition on the response of Saccharomyces cerevisiae to hydrostatic pressure stress. 2012 FEMS Yeast Res. pmid:22846157
de Sousa Ferreira Soares G et al. Spectroscopic and thermooxidative analysis of organic okra oil and seeds from Abelmoschus esculentus. 2012 ScientificWorldJournal pmid:22645459
Wiebe MG et al. Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates. 2012 BMC Biotechnol. pmid:22646156
Angell RJ et al. Fish oil supplementation maintains adequate plasma arachidonate in cats, but similar amounts of vegetable oils lead to dietary arachidonate deficiency from nutrient dilution. 2012 Nutr Res pmid:22652378
Itakura H et al. The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid. 2012 J. Atheroscler. Thromb. pmid:22653220
Das R et al. Preparation of linoleic acid-capped silver nanoparticles and their antimicrobial effect. 2012 IET Nanobiotechnol pmid:22559712
Burrows T et al. A comparative validation of a child food frequency questionnaire using red blood cell membrane fatty acids. 2012 Eur J Clin Nutr pmid:22378224
Vanek VW et al. A.S.P.E.N. position paper: Clinical role for alternative intravenous fat emulsions. 2012 Nutr Clin Pract pmid:22378798
Shin D et al. Effects of dietary combination of n-3 and n-9 fatty acids on the deposition of linoleic and arachidonic acid in broiler chicken meats. 2012 Poult. Sci. pmid:22399741
Billault I et al. Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes. 2012 Anal Bioanal Chem pmid:22349323
Lasa A et al. The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. 2011 Sep-Oct Nutr Hosp pmid:22072344
Okui T et al. Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. 2011 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:21723718
Mujtaba SF et al. Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities. 2011 Sep-Oct Photochem. Photobiol. pmid:21668866
Ramandi NF et al. Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. 2011 Nov-Dec J. Food Sci. pmid:22416687
Olszewska MA Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. 2011 Nov-Dec Acta Pol Pharm pmid:22125960
Olszewska MA In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. 2011 Nov-Dec Acta Pol Pharm pmid:22125961
Kezutyte T et al. Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. 2011 Nov-Dec Acta Pol Pharm pmid:22125963
China R et al. In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. 2011 Nov-Dec J. Food Sci. pmid:22416691
Permiakova MD and Trufanov VA [Effect of soybean lipoxygenae on baking properties of wheat flour]. 2011 May-Jun Prikl. Biokhim. Mikrobiol. pmid:21790037
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Lam YY et al. Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. 2011 Jul-Aug Biochim. Biophys. Acta pmid:21570480
de Luis DA et al. Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients. 2011 Jul-Aug Nutr Hosp pmid:22470031
Aluf Y et al. Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. 2011 Jul-Aug Neuropharmacology pmid:21414328
Jump DB et al. Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation. 2011 Biochem. Pharmacol. pmid:21184748
Penumetcha M et al. Modulation of leptin levels by oxidized linoleic acid: a connection to atherosclerosis? 2011 J Med Food pmid:21186986
Park HG et al. Production of conjugated linoleic acid (CLA) by Bifidobacterium breve LMC520 and its compatibility with CLA-producing rumen bacteria. 2011 J. Agric. Food Chem. pmid:21192703
Loizzo MR et al. In vitro antioxidant and hypoglycemic activities of Ethiopian spice blend Berbere. 2011 Int J Food Sci Nutr pmid:21599464
Kruska N and Reiser G Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. 2011 Neurobiol. Dis. pmid:21570468
Palmieri-Thiers C et al. Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies. 2011 Arch. Biochem. Biophys. pmid:21345329
Kishino S et al. Linoleic acid isomerase in Lactobacillus plantarum AKU1009a proved to be a multi-component enzyme system requiring oxidoreduction cofactors. 2011 Biosci. Biotechnol. Biochem. pmid:21307591
Royan M et al. Effects of conjugated linoleic acid, fish oil and soybean oil on PPARs (α & γ) mRNA expression in broiler chickens and their relation to body fat deposits. 2011 Int J Mol Sci pmid:22272093
Salleh WM et al. Chemical compositions, antioxidant and antimicrobial activities of essential oils of Piper caninum Blume. 2011 Int J Mol Sci pmid:22174627
Shofian NM et al. Effect of freeze-drying on the antioxidant compounds and antioxidant activity of selected tropical fruits. 2011 Int J Mol Sci pmid:21845104
Baâtour O et al. Salt effects on Origanum majorana fatty acid and essential oil composition. 2011 J. Sci. Food Agric. pmid:21800320
Toledo L et al. Substrate binding to mammalian 15-lipoxygenase. 2011 J. Comput. Aided Mol. Des. pmid:21861154
Vedtofte MS et al. Dietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease. 2011 Am. J. Clin. Nutr. pmid:21865326
Amtul Z et al. Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids. 2011 J. Neurosci. Res. pmid:21748777
Ilić M et al. Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities. 2011 Bioorg. Med. Chem. Lett. pmid:21757348
Mito F et al. Oxygen concentration dependence of lipid peroxidation and lipid-derived radical generation: application of profluorescent nitroxide switch. 2011 Free Radic. Res. pmid:21736483
Ranchordas MK et al. A-z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 23. 2011 Br J Sports Med pmid:21743106
Kikalishvili BIu et al. [The most biological important constances of Rkatsiteli grape oil and its effect as a 5% and 10% food-additive]. 2011 Georgian Med News pmid:21778549
Dailey MJ et al. Jejunal linoleic acid infusions require GLP-1 receptor signaling to inhibit food intake: implications for the effectiveness of Roux-en-Y gastric bypass. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21917638
Lee YJ and Jenkins TC Identification of enriched conjugated linoleic acid isomers in cultures of ruminal microorganisms after dosing with 1-(13)C-linoleic acid. 2011 J. Microbiol. pmid:21887646
Beker BY et al. Antioxidant protective effect of flavonoids on linoleic acid peroxidation induced by copper(II)/ascorbic acid system. 2011 Chem. Phys. Lipids pmid:21925488
Zhou XR et al. Caenorhabditis elegans Delta12-desaturase FAT-2 is a bifunctional desaturase able to desaturate a diverse range of fatty acid substrates at the Delta12 and Delta15 positions. 2011 J. Biol. Chem. pmid:22041902
Ogawa E et al. Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway. 2011 J. Invest. Dermatol. pmid:21068754
Odabasoglu F et al. α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations. 2011 Br. J. Nutr. pmid:21073761
Akrout A et al. Antioxidant and antitumor activities of Artemisia campestris and Thymelaea hirsuta from southern Tunisia. 2011 Food Chem. Toxicol. pmid:21075159
Cheng TM et al. Haemoglobin-induced oxidative stress is associated with both endogenous peroxidase activity and H2O2 generation from polyunsaturated fatty acids. 2011 Free Radic. Res. pmid:21034361
Lin YH et al. Altered essential fatty acid metabolism and composition in rat liver, plasma, heart and brain after microalgal DHA addition to the diet. 2011 J. Nutr. Biochem. pmid:21111595
Blaul B and Ruther J How parasitoid females produce sexy sons: a causal link between oviposition preference, dietary lipids and mate choice in Nasonia. 2011 Proc. Biol. Sci. pmid:21429922
Gibson RA et al. Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life. 2011 Matern Child Nutr pmid:21366864
Lauritzen L and Carlson SE Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status. 2011 Matern Child Nutr pmid:21366866
Brenna JT Animal studies of the functional consequences of suboptimal polyunsaturated fatty acid status during pregnancy, lactation and early post-natal life. 2011 Matern Child Nutr pmid:21366867
Briend A et al. Fatty acid status in early life in low-income countries--overview of the situation, policy and research priorities. 2011 Matern Child Nutr pmid:21366873
Blasbalg TL et al. Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. 2011 Am. J. Clin. Nutr. pmid:21367944
Edris AE The chemical composition and the content of volatile oil: potential factors that can contribute to the oxidative stability of Nigella sativa L. crude oil. 2011 J Diet Suppl pmid:22432633
Salem N and Kuratko CN Lack of evidence for increased α-linolenic acid metabolism in vegetarians. 2011 Am. J. Clin. Nutr. pmid:21430120
Hasegawa T et al. Constituents of the green tea seeds of Camellia sinensis. 2011 Nat Prod Commun pmid:21485277
Atri MS et al. Structure and stability analysis of cytotoxic complex of camel α-lactalbumin and unsaturated fatty acids produced at high temperature. 2011 J. Biomol. Struct. Dyn. pmid:21469752
Carrillo C et al. Oleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes. 2011 Cell. Physiol. Biochem. pmid:21471726