| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperpigmentation | D017495 | 11 associated lipids |
| Infertility, Male | D007248 | 11 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Migraine Disorders | D008881 | 11 associated lipids |
| Acute Coronary Syndrome | D054058 | 11 associated lipids |
| Muscular Dystrophy, Duchenne | D020388 | 11 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Hepatitis C, Chronic | D019698 | 12 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kääpä P et al. | Dietary fatty acids and platelet thromboxane production in puerperal women and their offspring. | 1986 | Am. J. Obstet. Gynecol. | pmid:3089014 |
| Youyou A et al. | Recovery of altered fatty acid composition induced by a diet devoid of n-3 fatty acids in myelin, synaptosomes, mitochondria, and microsomes of developing rat brain. | 1986 | J. Neurochem. | pmid:3940283 |
| Maddaiah VT and Clejan S | Growth hormone and liver mitochondria: time course of effects on respiration and fatty acid composition in hypophysectomized rats. | 1986 | Endocrinology | pmid:2941269 |
| Riemersma RA et al. | Linoleic acid content in adipose tissue and coronary heart disease. | 1986 | Br Med J (Clin Res Ed) | pmid:3087455 |
| Rapoport S et al. | Hydroperoxyfatty acids inactivate the reticulocyte lipoxygenase independently of a hydroperoxidase reaction. | 1986 | FEBS Lett. | pmid:3087777 |
| Okuno M et al. | Serum fatty acid concentrations in patients on postoperative parenteral nutrition with and without fat. | 1986 | Jpn J Surg | pmid:3088309 |
| Heagerty AM et al. | Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. | 1986 | Br Med J (Clin Res Ed) | pmid:3089491 |
| Wander RC and Berdanier CD | Effects of type of dietary fat and carbohydrate on gluconeogenesis in isolated hepatocytes from BHE rats. | 1986 | J. Nutr. | pmid:3091787 |
| Ng LL and Hockaday TD | Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. | 1986 | Br Med J (Clin Res Ed) | pmid:3092960 |
| Jones DB et al. | Indirect evidence of impairment of platelet desaturase enzymes in diabetes mellitus. | 1986 | Horm. Metab. Res. | pmid:3013745 |
| Parsons HG et al. | Modulation of human erythrocyte shape and fatty acids by diet. | 1986 | Biochim. Biophys. Acta | pmid:3741859 |
| Roguet R et al. | In vivo distribution of linoleic acid in hairless rat skin following topical administration. | 1986 | Arch. Dermatol. Res. | pmid:3789807 |
| Caponnetto A et al. | [Polyunsaturated fatty acids (omega-6) in tissues: variations induced by supplementation with linoleic acid and alloxan]. | 1986 | Boll. Soc. Ital. Biol. Sper. | pmid:3790314 |
| Nassar BA et al. | The influence of dietary manipulation with n-3 and n-6 fatty acids on liver and plasma phospholipid fatty acids in rats. | 1986 | Lipids | pmid:3796229 |
| de Gomez Dumm IN et al. | Effect of malonyl-CoA on delta 6 desaturation activity of rat liver microsomes. | 1986 | Lipids | pmid:3796237 |
| Effect of age on the linoleate content of skin acylglucosylceramide in mice. | 1986 | Nutr. Rev. | pmid:3796906 | |
| Utermohlen V and Tucker MA | Possible effects of dietary n-6 series polyunsaturated fatty acids on the development of immune dysfunction and infection. | 1986 | Proc Nutr Soc | pmid:3797410 |
| Lehmann J et al. | Vitamin E in foods from high and low linoleic acid diets. | 1986 | J Am Diet Assoc | pmid:3745745 |
| Fusco AC et al. | Schistosoma mansoni: production of cercarial eicosanoids as correlates of penetration and transformation. | 1986 | J. Parasitol. | pmid:3746561 |
| Holman RT | Nutritional and biochemical evidences of acyl interaction with respect to essential polyunsaturated fatty acids. | 1986 | Prog. Lipid Res. | pmid:3423089 |
| Hansen HS and Jensen B | Urinary excretion of arginine-vasopressin and prostaglandin E2 in essential fatty acid-deficient rats after oral supplementation with unsaturated fatty acid esters. | 1986 | J. Nutr. | pmid:3080561 |
| Leikin AI and Brenner RR | Regulation of linoleic acid delta 6-desaturation by a cytosolic lipoprotein-like fraction in isolated rat liver microsomes. | 1986 | Biochim. Biophys. Acta | pmid:2869785 |
| Wolfram G et al. | Pain, prostaglandins, and food lipids. Influences of dietary polyunsaturated fatty acids on eicosanoid synthesis and effects. | 1986 | Bibl Nutr Dieta | pmid:2870709 |
| Carlson SE et al. | High fat diets varying in ratios of polyunsaturated to saturated fatty acid and linoleic to linolenic acid: a comparison of rat neural and red cell membrane phospholipids. | 1986 | J. Nutr. | pmid:2871142 |
| Nijssen JG and van den Bosch H | Coenzyme A-mediated transacylation of sn-2 fatty acids from phosphatidylcholine in rat lung microsomes. | 1986 | Biochim. Biophys. Acta | pmid:3081034 |
| Abeywardena MY et al. | Effects of variable linoleate intake on aortic PGI2-like activity and fatty acid composition: difference between rat and marmoset (Callithrix jacchus). | 1986 | Prostaglandins Leukot Med | pmid:3103139 |
| Hawkey CJ et al. | Strategies for preventing aspirin-induced gastric bleeding. | 1986 | Scand. J. Gastroenterol. Suppl. | pmid:3103204 |
| Anderson RJ et al. | Peroxidised linoleic acid and experimental pancreatitis. | 1986 | Int. J. Pancreatol. | pmid:3681026 |
| Ishiura S et al. | Effects of linoleic acid and cations on the activity of a novel high-molecular weight protease, ingensin, from human placenta. | 1986 | Int. J. Biochem. | pmid:3530832 |
| Izumi Y et al. | Effects of dietary linoleic acid on blood pressure and renal function in subtotally nephrectomized rats. | 1986 | Proc. Soc. Exp. Biol. Med. | pmid:3532127 |
| Hoffmann P et al. | Cardiovascular actions of dihydralazine as modified by dietary linoleic acid. | 1986 | Biomed. Biochim. Acta | pmid:3535786 |
| Hoffmann P et al. | Circadian rhythm of eicosanoid formation as affected by dietary linoleate. | 1986 | Prostaglandins Leukot Med | pmid:3547416 |
| Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
| Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
| Stewart ME et al. | Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. | 1986 | J. Invest. Dermatol. | pmid:2946783 |
| Andersen GE et al. | Fatty acid changes in plasma lipids and lymphocyte phospholipids after infusion of intralipid to newborn infants. | 1985 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:3934403 |
| Burton AF and Anderson FH | Increased cholesteryl ester content in liver of mice fed lipid emulsion diets high in polyunsaturated fats. | 1985 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:3839859 |
| Buchanan MR et al. | 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. | 1985 | J. Biol. Chem. | pmid:3934168 |
| O'Brien PM et al. | The effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--a possible role in pregnancy-induced hypertension? | 1985 | Br J Clin Pharmacol | pmid:2985102 |
| Cunnane SC et al. | Essential fatty acids in the liver and adipose tissue of genetically obese mice: effect of supplemental linoleic and gamma-linolenic acids. | 1985 | Br. J. Nutr. | pmid:2998443 |
| Cunnane SC et al. | Abnormal essential fatty acid composition of tissue lipids in genetically diabetic mice is partially corrected by dietary linoleic and gamma-linolenic acids. | 1985 | Br. J. Nutr. | pmid:2998444 |
| Charnock JS et al. | Changes in fatty acid composition of the cardiac phospholipids of the cotton-eared marmoset (Callithrix jacchus) after feeding different lipid supplements. | 1985 | Ann. Nutr. Metab. | pmid:3922279 |
| Narce M and Poisson JP | [In vitro study of delta-6- and delta-5-desaturation of linoleic and dihomo-gamma-linolenic acids in WKY rats on a high-sodium diet]. | 1985 | C. R. Seances Soc. Biol. Fil. | pmid:2939926 |
| Hansen HS and Jensen B | Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate. | 1985 | Biochim. Biophys. Acta | pmid:3922424 |
| Nugteren DH et al. | Metabolism of linoleic acid and other essential fatty acids in the epidermis of the rat. | 1985 | Biochim. Biophys. Acta | pmid:3922425 |
| Margetts BM et al. | Blood pressure and dietary polyunsaturated and saturated fats: a controlled trial. | 1985 | Clin. Sci. | pmid:3905211 |
| Allen RE et al. | A serum-free medium that supports the growth of cultured skeletal muscle satellite cells. | 1985 | In Vitro Cell. Dev. Biol. | pmid:3905759 |
| Carroll KK | Dietary fat in relation to mammary carcinogenesis. | 1985 | Int. Symp. Princess Takamatsu Cancer Res. Fund | pmid:3916197 |
| Ip C et al. | Requirement of essential fatty acid for mammary tumorigenesis in the rat. | 1985 | Cancer Res. | pmid:3921234 |
| Stumpf DA | The inherited ataxias. | 1985 | Neurol Clin | pmid:3921817 |
| Lankin VZ et al. | On the nature of the stimulation of the lipoxygenase from rabbit reticulocytes by biological membranes. | 1985 | Biomed. Biochim. Acta | pmid:3933493 |
| Yoshikawa H et al. | Potentiation of antitumor effect of bleomycin by lipid-surfactant mixed micelles. I. In vivo and tumor-neutralizing activity against mouse Ehrlich ascites tumor and rat ascites hepatoma AH66. | 1985 | J. Pharmacobio-dyn. | pmid:2411907 |
| Wolff JA et al. | The role of lipid in the management of methylmalonic acidaemia: administration of linoleic acid does not increase excretion of methylmalonic acid. | 1985 | J. Inherit. Metab. Dis. | pmid:3939583 |
| Jäntti J et al. | Linoleic acid treatment in inflammatory arthritis. | 1985 | Int J Clin Pharmacol Ther Toxicol | pmid:3886567 |
| Sugita A et al. | [Serum long chain fatty acids in the patients with inflammatory bowel disease]. | 1985 | Nihon Shokakibyo Gakkai Zasshi | pmid:3990036 |
| Adam O et al. | Prostaglandin formation and platelet aggregation during fasting and linoleic acid intake. | 1985 | Res Exp Med (Berl) | pmid:3992060 |
| Válek J et al. | Serum linoleic acid and cardiovascular death in postinfarction middle-aged men. | 1985 | Atherosclerosis | pmid:3994777 |
| Tsuchida M et al. | Fluorescent substances in mouse and human sera as a parameter of in vivo lipid peroxidation. | 1985 | Biochim. Biophys. Acta | pmid:3995061 |
| Bowser PA et al. | Identification, isolation and characterization of epidermal lipids containing linoleic acid. | 1985 | Biochim. Biophys. Acta | pmid:3995076 |
| Demant EJ and Wassermann K | Doxorubicin induced alterations in lipid metabolism of cultured myocardial cells. | 1985 | Biochem. Pharmacol. | pmid:4004891 |
| Robinson M et al. | Acylation of lysophospholipids by rabbit alveolar macrophages. Specificities of CoA-dependent and CoA-independent reactions. | 1985 | J. Biol. Chem. | pmid:4008481 |
| McMaster JD et al. | Incorporation in vitro of 14C fatty acids into bovine sebaceous gland and dermal lipids. | 1985 | Res. Vet. Sci. | pmid:4012036 |
| Howard-Williams J et al. | Polyunsaturated fatty acids and diabetic retinopathy. | 1985 | Br J Ophthalmol | pmid:3965024 |
| Montalto MB et al. | Nutrient intakes of formula-fed infants and infants fed cow's milk. | 1985 | Pediatrics | pmid:3969338 |
| Reid JC and Husbands DR | Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. | 1985 | Biochem. J. | pmid:3977825 |
| Vergroesen AJ | Effects of dietary lipid composition on serum lipoproteins. | 1985 | Prog. Clin. Biol. Res. | pmid:3903769 |
| Noble RC et al. | Synthesis of C20 and C22 polyunsaturated fatty acids by the placenta of the sheep. | 1985 | Biol. Neonate | pmid:4027296 |
| Goldstein R et al. | Increased maternal-fetal transport of fat in diabetes assessed by polyunsaturated fatty acid content in fetal lipids. | 1985 | Biol. Neonate | pmid:4027297 |
| Jett M et al. | Metabolic fate of liposomal phosphatidylinositol in murine tumor cells: implications for the mechanism of tumor cell cytotoxicity. | 1985 | Cancer Res. | pmid:4027970 |
| Takada K et al. | Promotion of the selective lymphatic delivery of cyclosporin A by lipid-surfactant mixed micelles. | 1985 | J. Pharmacobio-dyn. | pmid:4032221 |
| Kanazawa K et al. | Uptake of secondary autoxidation products of linoleic acid by the rat. | 1985 | Lipids | pmid:4033361 |
| Martinez GA et al. | Nutrient intakes of American infants and children fed cow's milk or infant formula. | 1985 | Am. J. Dis. Child. | pmid:4036886 |
| Roshanai F and Sanders TA | Influence of different supplements of N-3 polyunsaturated fatty acids on blood and tissue lipids in rats receiving high intakes of linoleic acid. | 1985 | Ann. Nutr. Metab. | pmid:4037727 |
| Takahashi K et al. | Ester-exchange catalyzed by lipase modified with polyethylene glycol. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4052065 |
| Hennig B et al. | Exposure to fatty acid increases human low density lipoprotein transfer across cultured endothelial monolayers. | 1985 | Circ. Res. | pmid:4053308 |
| Hagve TA et al. | Norflurazon--an inhibitor of essential fatty acid desaturation in isolated liver cells. | 1985 | Lipids | pmid:4058269 |
| Barclay LR et al. | The antioxidant activity of alpha-tocopherol-bovine serum albumin complex in micellar and liposome autoxidations. | 1985 | J. Biol. Chem. | pmid:4066696 |
| Mathias MM and Dupont J | Quantitative relationships between dietary linoleate and prostaglandin (eicosanoid) biosynthesis. | 1985 | Lipids | pmid:4068908 |
| Potter LM and McCarthy JP | Varying fat and protein in diets of growing large white turkeys. | 1985 | Poult. Sci. | pmid:4070128 |
| Clark DL and Queener SF | Effects of diabetes mellitus on renal fatty acid activation and desaturation. | 1985 | Biochem. Pharmacol. | pmid:4074391 |
| Isseroff RR et al. | Alterations in fatty acid composition of murine keratinocytes with in vitro cultivation. | 1985 | J. Invest. Dermatol. | pmid:3926903 |
| Giamalva D et al. | A comparison of the rates of ozonation of biological antioxidants and oleate and linoleate esters. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084297 |
| Ford GL | Semi-preparative isolation of crepenynic acid, a potential inhibitor of essential fatty acid metabolism. | 1985 | J. Chromatogr. | pmid:4086624 |
| Salo MK et al. | Platelet aggregation in Finnish men and its relation to fatty acids in platelets, plasma and adipose tissue. | 1985 | Thromb. Haemost. | pmid:4089791 |
| Adam O et al. | [The effect of linoleic acid intake on its concentration and resultant products in individual plasma lipids in humans]. | 1985 | Z Ernahrungswiss | pmid:4096032 |
| Pascaud M and Strouve-Vallet C | Desaturation of 14C linoleic acid by the rat fetus. | 1985 | Ann. Nutr. Metab. | pmid:2983600 |
| Nordøy A et al. | Effect of dietary (n--3) fatty acids on platelet function and lipid metabolism in rats. | 1985 | Biochim. Biophys. Acta | pmid:2861854 |
| Fusco AC et al. | Schistosoma mansoni: eicosanoid production by cercariae. | 1985 | Exp. Parasitol. | pmid:3917929 |
| Jones PJ et al. | Whole body oxidation of dietary fatty acids: implications for energy utilization. | 1985 | Am. J. Clin. Nutr. | pmid:3933323 |
| Levinson S et al. | Comparison of intraluminal and intravenous mediators of colonic response to eating. | 1985 | Dig. Dis. Sci. | pmid:3838089 |
| Farrell PM et al. | Fatty acid abnormalities in cystic fibrosis. | 1985 | Pediatr. Res. | pmid:3918287 |
| Kort WJ et al. | Spontaneous tumor incidence in female brown Norway rats after lifelong diets high and low in linoleic acid. | 1985 | J. Natl. Cancer Inst. | pmid:3856059 |
| Smith MT and Thompson S | Free radicals and alcoholics. | 1985 | Lancet | pmid:2864501 |
| Stoeck M et al. | Studies on the mechanism whereby cyclosporin A inhibits T-lymphocyte activation. | 1985 | Immunobiology | pmid:2580777 |
| Boberg M et al. | Platelet fatty acid composition in relation to fatty acid composition in plasma and to serum lipoprotein lipids in healthy subjects with special reference to the linoleic acid pathway. | 1985 | Clin. Sci. | pmid:3919990 |
| Poisson JP | Comparative in vivo and in vitro study of the influence of experimental diabetes on rat liver linoleic acid delta 6- and delta 5-desaturation. | 1985 | Enzyme | pmid:3002783 |
| Erskine KJ et al. | An altered ratio of 18:2 (9,11) to 18:2 (9,12) linoleic acid in plasma phospholipids as a possible predictor of pre-eclampsia. | 1985 | Lancet | pmid:2857904 |
| Clarke SD and Salati LM | Fatty acid-mediated disaggregation of acetyl-CoA carboxylase in isolated liver cells. | 1985 | Fed. Proc. | pmid:2859222 |
| Fink R et al. | Increased free-radical activity in alcoholics. | 1985 | Lancet | pmid:2862465 |
| Salzmann-Reinhardt U et al. | Metabolism of polyunsaturated fatty acids by rabbit reticulocytes. | 1985 | Eur. J. Biochem. | pmid:3933978 |