| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemia, Familial Combined | D006950 | 9 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:26984340 | ||||
| pmid:26189725 | ||||
| pmid:25781458 | ||||
| pmid:25770319 | ||||
| pmid:26606689 | ||||
| pmid:26593514 | ||||
| pmid:25418937 | ||||
| pmid:25418385 | ||||
| pmid:25373090 | ||||
| pmid:24996268 | ||||
| pmid:24954845 | ||||
| pmid:24642113 | ||||
| pmid:23675697 | ||||
| pmid:23477411 | ||||
| pmid:26646740 | ||||
| pmid:27240678 | ||||
| pmid:28646265 | ||||
| pmid:27374577 | ||||
| pmid:27855909 | ||||
| pmid:27886515 | ||||
| pmid:25771044 | ||||
| pmid:27378407 | ||||
| pmid:27374549 | ||||
| pmid:26971161 | ||||
| pmid:29359556 | ||||
| pmid:26950614 | ||||
| pmid:14273071 | ||||
| pmid:19200116 | ||||
| pmid: | ||||
| pmid:12790685 | ||||
| pmid:1684095 | ||||
| pmid:1802216 | ||||
| Wu J et al. | Metabolite profiles of rice cultivars containing bacterial blight-resistant genes are distinctive from susceptible rice. | 2012 | Acta Biochim. Biophys. Sin. (Shanghai) | pmid:22687573 |
| Jarmuszkiewicz W et al. | The contribution of uncoupling protein and ATP synthase to state 3 respiration in Acanthamoeba castellanii mitochondria. | 2004 | Acta Biochim. Pol. | pmid:15218546 |
| Stepień K et al. | Peroxynitrite mediated linoleic acid oxidation and tyrosine nitration in the presence of synthetic neuromelanins. | 2000 | Acta Biochim. Pol. | pmid:11996116 |
| Wei DSh et al. | A novel Delta12-fatty acid desaturase gene from methylotrophic yeast Pichia pastoris GS115. | 2006 | Acta Biochim. Pol. | pmid:17063209 |
| Luo C et al. | Vegetable oil thermosets reinforced by tannin-lipid formulations. | 2013 | Acta Biomater | pmid:22975626 |
| Judd JT and Clevidence BA | Trans fatty acids in human nutrition. | 1993 | Acta Cardiol | pmid:8284978 |
| Magalhães MS et al. | Effect of a combination of medium chain triglycerides, linoleic acid, soy lecithin and vitamins A and E on wound healing in rats. | 2008 May-Jun | Acta Cir Bras | pmid:18552998 |
| Lloyd T et al. | Purification, crystallization and preliminary X-ray diffraction analysis of pathogen-inducible oxygenase (PIOX) from Oryza sativa. | 2006 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:16582486 |
| Ponec M et al. | Covalently bound lipids in reconstructed human epithelia. | 2000 Mar-Apr | Acta Derm. Venereol. | pmid:10877125 |
| SENO S et al. | LOOSENING OF THE CYTOMEMBRANE OF EHRLICH ASCITES TUMOR CELL BY UNSATURATED FATTY ACID. | 1964 | Acta Med Okayama | pmid:14222359 |
| Yoshida M et al. | Linoleate and fatty acid compositions in the serum lipids of Japanese patients with multiple sclerosis. | 1983 | Acta Neurol. Scand. | pmid:6364685 |
| Mcgregor L et al. | Effects of dietary linoleic acid and gamma linolenic acid on platelets of patients with multiple sclerosis. | 1989 | Acta Neurol. Scand. | pmid:2782038 |
| Fisher M et al. | Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients. | 1987 | Acta Neurol. Scand. | pmid:3687373 |
| Reyes MR et al. | Estrogens are potentially the only steroids with an antioxidant role in pregnancy: in vitro evidence. | 2006 | Acta Obstet Gynecol Scand | pmid:16929413 |
| Gere A et al. | Fatty acid composition of human milk and milk-based formulas in Hungary. | 1983 | Acta Paediatr Hung | pmid:6613576 |
| Fernandes J et al. | The effect of a virtually cholesterol-free, high-linoleic-acid vegetarian diet on serum lipoproteins of children with familial hypercholesterolemia (type II-A). | 1981 | Acta Paediatr Scand | pmid:7324917 |
| Moilanen T et al. | Atherosclerosis precursors in Finnish children and adolescents. V. Fatty acid composition of serum cholesteryl esters: regional differences in Finland. | 1985 | Acta Paediatr Scand Suppl | pmid:3867222 |
| HANSEN AE et al. | The relation of linoleic acid to infant feeding. | 1962 | Acta Paediatr Suppl | pmid:13952587 |
| Decsi T et al. | Polyunsaturated fatty acids in plasma lipids of diabetic children during and after diabetic ketoacidosis. | 2005 | Acta Paediatr. | pmid:16188805 |
| Svahn JC et al. | Different quantities and quality of fat in milk products given to young children: effects on long chain polyunsaturated fatty acids and trans fatty acids in plasma. | 2002 | Acta Paediatr. | pmid:11885548 |
| Agostoni C | The difficult balance between dietary polyunsaturated fatty acids. | 2003 | Acta Paediatr. | pmid:14971782 |
| Thiombiano-Coulibaly N et al. | Seasonal and environmental effects on breast milk fatty acids in Burkina Faso and the need to improve the omega 3 PUFA content. | 2003 | Acta Paediatr. | pmid:14971787 |
| Leichsenring M et al. | Polyunsaturated fatty acids in erythrocyte and plasma lipids of children with severe protein-energy malnutrition. | 1995 | Acta Paediatr. | pmid:7633146 |
| van Zoeren-Grobben D et al. | Lipid peroxidation in human milk and infant formula: effect of storage, tube feeding and exposure to phototherapy. | 1993 | Acta Paediatr. | pmid:8374211 |
| Lundell KH et al. | Plasma metabolites after a lipid load in infants with congenital heart disease. | 1999 | Acta Paediatr. | pmid:10447129 |
| Biagi PL et al. | Erythrocyte membrane fatty acid composition in children with atopic dermatitis compared to age-matched controls. | 1993 | Acta Paediatr. | pmid:8241678 |
| ARFFMANN E | HEATED FATS AND ALLIED COMPOUNDS AS CARCINOGENS; STUDIED BY THE NEWT TEST. | 1964 | Acta Pathol Microbiol Scand | pmid:14162795 |
| Kadifkova Panovska T et al. | In vitro antioxidant activity of some Teucrium species (Lamiaceae). | 2005 | Acta Pharm | pmid:16179134 |
| Jensen GE and Clausen J | Glutathione peroxidase activity, associated enzymes and substrates in blood cells from patients with multiple sclerosis--effects of antioxidant supplementation. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3776606 |
| Yang XF et al. | In vitro release and antibacterial activity of poly (oleic/linoleic acid dimer: sebacic acid)-gentamicin. | 2003 | Acta Pharmacol. Sin. | pmid:12676068 |
| Xu QY et al. | Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. | 2014 | Acta Pharmacol. Sin. | pmid:25220639 |
| Cui YF et al. | Effect of unsaturated fatty acid on muscarinic current in guinea pig gastric antral circular myocytes. | 2003 | Acta Pharmacol. Sin. | pmid:12617780 |
| Grójec M and Kaleta Z | The composition of fatty acids of the serum and erythrocytes after an alimentary cholesterol load. | 1984 Mar-Apr | Acta Physiol Pol | pmid:6537129 |
| HAUGE JG and NICOLAYSEN R | The serum cholesterol depressive effect of linoleic, linolenic acids and of cod liver oil in experimental hypercholesterolaemic rats. | 1959 | Acta Physiol. Scand. | pmid:13626601 |
| BLOMSTRAND R | The intestinal absorption of linoleic-1-14C acid. | 1954 | Acta Physiol. Scand. | pmid:13228101 |
| Alinezhad H et al. | Biochemical activities of acetone extracts of Hyssopus angustifolius. | 2012 Jul-Aug | Acta Pol Pharm | pmid:22876603 |
| Moghaddam AH et al. | Antioxidant, antihemolytic and nephroprotective activity of aqueous extract of Diospyros lotus seeds. | 2012 Jul-Aug | Acta Pol Pharm | pmid:22876611 |
| Ozen T | Investigation of antioxidant properties of Nasturtium officinale (watercress) leaf extracts. | 2009 Mar-Apr | Acta Pol Pharm | pmid:19719054 |
| Olszewska MA | Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125960 |
| Olszewska MA | In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125961 |
| Kezutyte T et al. | Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125963 |
| Baek JH et al. | Lithium tremor revisited: pathophysiology and treatment. | 2014 | Acta Psychiatr Scand | pmid:23834617 |
| Leichsenring M et al. | Scaly skin alterations and plasma fatty acids in Congolese children. | 1993 | Acta Trop. | pmid:7902652 |
| TANHUANPAEAE E | STUDIES ON THE INFLUENCE OF DIETARY METHYL LINOLEATE ON SWINE TISSUE LIPIDS WITH SPECIAL REFERENCE TO NUTRITIONAL MUSCULAR AND LIVE DYSTROPHY. | 1965 | Acta Vet. Scand. | pmid:14298292 |
| PASQUALI W | [Determination of arachidonic, linolenic and linoleic (vitamin F) acid in milk and blood. II. Determination in the milk]. | 1954 | Acta Vitaminol | pmid:13171149 |
| CORSINI F | [Assay of linoleic, linolenic and arachidonic acids in milk and blood. III. Determination in blood]. | 1956 | Acta Vitaminol | pmid:13339550 |
| Tarozzi G et al. | Fatty acid composition of single brain structures following different alpha linolenate dietary supplementations. | 1984 | Acta Vitaminol. Enzymol. | pmid:6098184 |
| Turchetto E and Pignatti C | [Protection of essential fatty acids by vitamin E]. | 1982 | Acta Vitaminol. Enzymol. | pmid:6293292 |
| Ermidou-Pollet S et al. | Influence of subcutaneous injection of essential fatty acids on the stress-induced modifications of rat platelet aggregation and membrane lipid composition. | 2005 | Acta. Biol. Hung. | pmid:16196200 |
| Arawwawala M et al. | In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. | 2011 | Acta. Biol. Hung. | pmid:21840826 |
| Guyenet SJ and Carlson SE | Increase in adipose tissue linoleic acid of US adults in the last half century. | 2015 | Adv Nutr | pmid:26567191 |
| Whelan J and Fritsche K | Linoleic acid. | 2013 | Adv Nutr | pmid:23674797 |
| Birnbaum L | Addition of conjugated linoleic acid to a herbal anticellulite pill. | 2001 Sep-Oct | Adv Ther | pmid:11783459 |
| Cook ME | Nutritional effects on vaccination. | 1999 | Adv Vet Med | pmid:9890009 |
| GIBSON DM and ALLMANN DW | ADAPTIVE CHANGES IN FATTY ACID BIOSYNTHESIS. | 1963 | Adv. Enzyme Regul. | pmid:14190353 |
| Sauerwald TU et al. | Polyunsaturated fatty acid supply with human milk. Physiological aspects and in vivo studies of metabolism. | 2000 | Adv. Exp. Med. Biol. | pmid:11065079 |
| Del Prado M et al. | Contribution of dietary and newly formed arachidonic acid to milk secretion in women on low fat diets. | 2000 | Adv. Exp. Med. Biol. | pmid:11065105 |
| Lance A et al. | 13C-linoleic acid oxidation and transfer into milk in lactating women with contrasting body mass index. | 2000 | Adv. Exp. Med. Biol. | pmid:11065106 |
| Egashira Y et al. | Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serum. | 2003 | Adv. Exp. Med. Biol. | pmid:15206789 |
| Brash AR et al. | Investigation of a second 15S-lipoxygenase in humans and its expression in epithelial tissues. | 1999 | Adv. Exp. Med. Biol. | pmid:10667314 |
| Buchanan MR | Linoleic acid metabolites in health and disease. | 1999 | Adv. Exp. Med. Biol. | pmid:10667369 |
| Greene JF and Hammock BD | Toxicity of linoleic acid metabolites. | 1999 | Adv. Exp. Med. Biol. | pmid:10667370 |
| Gibson RA et al. | Long chain omega 3 polyunsaturates in formula-fed term infants. | 1992 | Adv. Exp. Med. Biol. | pmid:1353286 |
| Tanaka R et al. | Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. | 2012 | Adv. Exp. Med. Biol. | pmid:22259110 |
| Hörnsten L et al. | Bisallylic hydroxylation of linoleic and arachidonic acids by adult and fetal human liver microsomes and a comparison with human recombinant cytochromes P450. | 1997 | Adv. Exp. Med. Biol. | pmid:9561118 |
| Riambau V et al. | Effect of linoleic acid supplements on vessel wall hyperplasia in rabbits. | 1997 | Adv. Exp. Med. Biol. | pmid:9561150 |
| Brister SJ and Buchanan MR | Effects of linoleic acid and/or marine fish oil supplements on vessel wall thromboresistance in patients undergoing cardiac surgery. | 1997 | Adv. Exp. Med. Biol. | pmid:9561151 |
| Giménez-Arnau A et al. | Effects of linoleic acid supplements on atopic dermatitis. | 1997 | Adv. Exp. Med. Biol. | pmid:9561153 |