| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemia, Familial Combined | D006950 | 9 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bandyopadhyay GK et al. | Evidence for the inability of the catfish Heteropneustes fossilis & Clarias batrachus, to biosynthesize linoleic & linolenic acids. | 1982 | Indian J. Biochem. Biophys. | pmid:6299932 |
| Hoelgaard A and Møllgaard B | Permeation of linoleic acid through skin in vitro. | 1982 | J. Pharm. Pharmacol. | pmid:6127396 |
| Anderson RL | Quantitation of the effects of trans isomers of linoleic acid on the metabolism of linoleic acid. | 1982 | Am. J. Clin. Nutr. | pmid:7081132 |
| Eisen EJ et al. | Rates of depletion of linoleic acid from fat depots of selected lines of mice differing in growth rate and adiposity. | 1982 | Lipids | pmid:7087689 |
| Mogenson GJ and Box BM | Physiological effects of varying dietary linoleic acid in spontaneously hypertensive rats. | 1982 | Ann. Nutr. Metab. | pmid:7137945 |
| Adam O et al. | Prostaglandin formation in man during intake of different amounts of linoleic acid in formula diets. | 1982 | Ann. Nutr. Metab. | pmid:7137955 |
| Moore CE and Dhopeshwarkar GA | Trans fatty acids: transport and positional specificity in rat placental lecithin. | 1982 | Biol. Neonate | pmid:7138987 |
| Miura S et al. | Lymphatic role in the pathogenesis of fat malabsorption in liver cirrhosis in rats. | 1982 | Dig. Dis. Sci. | pmid:7140488 |
| Rosenblum WI | Unsaturated fatty acids and cyclooxygenase inhibitors: effects on pial arterioles. | 1982 | Am. J. Physiol. | pmid:6801999 |
| Cuebas D and Schulz H | Evidence for a modified pathway of linoleate degradation. Metabolism of 2,4-decadienoyl coenzyme A. | 1982 | J. Biol. Chem. | pmid:7142199 |
| Iritani N and Ikeda Y | Activation of catalase and other enzymes by corn oil intake. | 1982 | J. Nutr. | pmid:7143106 |
| Hølmer G et al. | Influence of partially hydrogenated vegetable and marine oils on lipid metabolism in rat liver and heart. | 1982 | Lipids | pmid:7144446 |
| Hoffmann P et al. | Alterations in renal and aortic prostaglandin E and F formation correlate with blood pressure dietary linoleate deficiency. | 1982 | Arch Int Pharmacodyn Ther | pmid:7181575 |
| Cunnane SC | Differential regulation of essential fatty acid metabolism to the prostaglandins: possible basis for the interaction of zinc and copper in biological systems. | 1982 | Prog. Lipid Res. | pmid:7051042 |
| Shimp JL et al. | The effects of dietary trilinoelaidin on fatty acid and acyl desaturases in rat liver. | 1982 | J. Nutr. | pmid:6802940 |
| Needleman SW et al. | Enrichment of human platelet phospholipids with linoleic acid diminishes thromboxane release. | 1982 | Prostaglandins | pmid:6819602 |
| Darfler FJ and Insel PA | Serum-free culture of resting, PHA-stimulated, and transformed lymphoid cells, including hybridomas. | 1982 | Exp. Cell Res. | pmid:7042376 |
| Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: I. Design of the study, material and methods. | 1982 | Can J Neurol Sci | pmid:7049340 |
| Melancon SB et al. | Oral lecithin and linoleic acid in Friedreich's ataxia: II. Clinical results. | 1982 | Can J Neurol Sci | pmid:7049341 |
| Rosenthal MD and Whitehurst MC | Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. | 1982 | J. Cell. Physiol. | pmid:6294123 |
| Christophersen BO et al. | Studies on the regulation of arachidonic acid synthesis in isolated rat liver cells. | 1982 | Biochim. Biophys. Acta | pmid:6812639 |
| Haataja M et al. | Prostaglandin precursors in rheumatoid arthritis. | 1982 Jan-Feb | J. Rheumatol. | pmid:7086783 |
| Rationale of the diet-heart statement of the American Heart Association. Report of the AHA nutrition committee. | 1982 Mar-Apr | Arteriosclerosis | pmid:7039581 | |
| Goodnight SH et al. | Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. | 1982 Mar-Apr | Arteriosclerosis | pmid:7039582 |
| Tobian L et al. | Influence of renal prostaglandins and dietary linoleate on hypertension in Dahl S rats. | 1982 May-Jun | Hypertension | pmid:6950924 |
| Kaduce TL et al. | Linoleic acid metabolism and prostaglandin production by cultured bovine pulmonary artery endothelial cells. | 1982 Sep-Oct | Arteriosclerosis | pmid:6751307 |
| Rosenthal MD and Whitehurst MC | Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6615875 |
| Rosenthal MD and Whitehurst MC | Fatty acyl delta 6 desaturation activity of cultured human endothelial cells. Modulation by fetal bovine serum. | 1983 | Biochim. Biophys. Acta | pmid:6297606 |
| Oliw EH | Oxygenation of linolenic and linoleic acid to novel vicinal dihydroxy acids by hepatic microsomes of the rabbit. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6301473 |
| Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
| Linoleic acid, prostaglandin synthesis and chronic renal failure in rats. | 1983 | Nutr. Rev. | pmid:6341898 | |
| Yoshida M et al. | Linoleate and fatty acid compositions in the serum lipids of Japanese patients with multiple sclerosis. | 1983 | Acta Neurol. Scand. | pmid:6364685 |
| Rustin P et al. | Oxidative interactions between fatty acid peroxy radicals and quinones: possible involvement in cyanide-resistant electron transport in plant mitochondria. | 1983 | Arch. Biochem. Biophys. | pmid:6414377 |
| Anggård E | Ethanol, essential fatty acids and prostaglandins. | 1983 | Pharmacol. Biochem. Behav. | pmid:6415673 |
| Shechter G and Grossman S | Lipoxygenase from baker's yeast: purification and properties. | 1983 | Int. J. Biochem. | pmid:6416906 |
| Campbell TB and Lueking DR | Long-chain fatty acid assimilation By rhodopseudomonas sphaeroides. | 1983 | J. Bacteriol. | pmid:6600450 |
| Nemoto N and Takayama S | Effects of unsaturated fatty acids on metabolism of benzo[a]pyrene in an NADPH-fortified rat liver microsomal system. | 1983 | Carcinogenesis | pmid:6311450 |
| Horrobin DF and Manku MS | How do polyunsaturated fatty acids lower plasma cholesterol levels? | 1983 | Lipids | pmid:6312241 |
| Høy CE et al. | Acyl group distributions in tissue lipids of rats fed evening primrose oil (gamma -linolenic plus linoleic acid) or soybean oil (alpha-linolenic plus linoleic acid). | 1983 | Lipids | pmid:6318009 |
| Nicholson T and Omer SA | The application of cumulative sum analysis to the investigation of reticulum motility in ruminant animals. | 1983 | Zentralbl Veterinarmed A | pmid:6318476 |
| Kirstein D et al. | Effect of dietary fats on the delta 6- and delta 5-desaturation of fatty acids in rat liver microsomes. | 1983 | Br. J. Nutr. | pmid:6315055 |
| Spector AA et al. | Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells. | 1983 | J. Lipid Res. | pmid:6321621 |
| Sanders TA | Dietary fat and platelet function. | 1983 | Clin. Sci. | pmid:6309463 |
| Goldmacher VS | Immobilization of protein molecules on liposomes. Anchorage by artificially bound unsaturated hydrocarbon tails. | 1983 | Biochem. Pharmacol. | pmid:6189496 |
| Gerzer R et al. | Calcium-induced release from platelet membranes of fatty acids that modulate soluble guanylate cyclase. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6134818 |
| Frankel EN | Volatile lipid oxidation products. | 1983 | Prog. Lipid Res. | pmid:6306693 |
| Gere A et al. | Fatty acid composition of human milk and milk-based formulas in Hungary. | 1983 | Acta Paediatr Hung | pmid:6613576 |
| Lloyd D et al. | Adaptive changes in yeast membranes: catabolite repression and oxygen. | 1983 | Biochem. Soc. Trans. | pmid:6617968 |
| Eckart J et al. | [Current status of parenteral feeding with fat emulsions. Clinical experiences with infected patients]. | 1983 | Infusionsther Klin Ernahr | pmid:6618658 |
| Derambure S et al. | [Platelet aggregation and platelet and plasma fatty acid levels in the child with migraine. Apropos of 40 case reports]. | 1983 | Pediatrie | pmid:6674921 |
| Kreutter D et al. | The effect of essential fatty acid deficiency on the stimulation of intestinal calcium transport by 1,25-dihydroxyvitamin D3. | 1983 | J. Biol. Chem. | pmid:6687596 |
| Lejman W et al. | Increase in the linoleic acid level in pulmonary surfactant in the rabbit after exposure to high oxygen concentration. | 1983 | Folia Biol. (Krakow) | pmid:6689156 |
| Shand JH and Noble RC | The characterization of the linoleic acid desaturation and elongation system in ovine placental tissue. | 1983 | Int. J. Biochem. | pmid:6642054 |
| Rapp JH et al. | Lipids of human atherosclerotic plaques and xanthomas: clues to the mechanism of plaque progression. | 1983 | J. Lipid Res. | pmid:6644183 |
| Jones R et al. | The analysis of the red cell unsaturated fatty acid test for multiple sclerosis using laser cytopherometry. | 1983 | Phys Med Biol | pmid:6647546 |
| MacDonald ML et al. | Role of linoleate as an essential fatty acid for the cat independent of arachidonate synthesis. | 1983 | J. Nutr. | pmid:6408230 |
| Gavigan SJ and Knight BL | The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. | 1983 | Biochem. J. | pmid:6651782 |
| Jones R et al. | Monitoring changes in the blood of patients with multiple sclerosis. | 1983 | Prog. Brain Res. | pmid:6665128 |
| Hoover RL et al. | Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes. | 1983 | J. Cell Biol. | pmid:6223042 |
| George AM et al. | Effect of membrane fatty acid changes on the radiation sensitivity of human lymphoid cells. | 1983 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:6601634 |
| Greenway DL and Dyke KG | The effect of membrane-bound beta-lactamase on linoleic acid sensitivity in Staphylococcus aureus. | 1983 | J. Gen. Microbiol. | pmid:6605415 |
| Pavelka M and Gangl A | Effects of colchicine on the intestinal transport of endogenous lipid. Ultrastructural, biochemical, and radiochemical studies in fasting rats. | 1983 | Gastroenterology | pmid:6822325 |
| Breton M et al. | Linoleate incorporation into rat liver membranes phospholipids: effect on plasma membrane ATPase activities and physical properties. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6230079 |
| Monnier LH et al. | Plasma lipid fatty acids and platelet function in insulin-dependent diabetic patients. | 1983 | Diabete Metab | pmid:6230269 |
| O'Brien PM and Broughton Pipkin F | The effect of essential fatty acid and specific vitamin supplements on vascular sensitivity in the mid-trimester of human pregnancy. | 1983 | Clin Exp Hypertens B | pmid:6872286 |
| Purvis JM et al. | Chain elongation-desaturation of linoleic acid during the development of the pig. Implications for the supply of polyenoic fatty acids to the developing brain. | 1983 | Comp. Biochem. Physiol., B | pmid:6872512 |
| Weber EJ | Variation in corn (Zea mays L.) for fatty acid compositions of triglycerides and phospholipids. | 1983 | Biochem. Genet. | pmid:6838482 |
| Cho BH | Lipid composition and cholesterol esterifying activity in microsomal preparations of porcine coronary arteries and heart tissue. | 1983 | Biochem Med | pmid:6838501 |
| Shultz TD and Leklem JE | Selenium status of vegeterians, nonvegetarians, and hormone-dependent cancer subjects. | 1983 | Am. J. Clin. Nutr. | pmid:6849273 |
| Charnock JS et al. | Differences in the fatty acid composition of atrial and ventricular phospholipids of rat heart following standard and lipid-supplemented diets. | 1983 | Comp. Biochem. Physiol., B | pmid:6851485 |
| Arudi RL et al. | Purification of oleic acid and linoleic acid. | 1983 | J. Lipid Res. | pmid:6854155 |
| Kanner J and Kinsella JE | Initiation of lipid peroxidation by a peroxidase/hydrogen peroxide/halide system. | 1983 | Lipids | pmid:6855480 |
| Glick JM and Adelman SJ | Established cell lines from rat adipose tissue that secrete lipoprotein lipase. | 1983 | In Vitro | pmid:6862515 |
| Ookhtens M and Baker N | Incomplete free fatty acid oxidation by ascites tumor cells under low oxygen tension. | 1983 | Am. J. Physiol. | pmid:6295191 |
| Ries W et al. | Selected metabolic results of the Leipzig gerontological longitudinal study. | 1983 Mar-Apr | Z Alternsforsch | pmid:6868654 |
| Hoffmann P et al. | Impaired catecholamine inactivation. A prohypertensive stimulus after dietary linoleate deficiency in salt-loaded rats? | 1983 Nov-Dec | Hypertension | pmid:6581124 |
| Sohal RS et al. | Relationship between lipofuscin granules and polyunsaturated fatty acids in the housefly, Musca domestica. | 1984 | Mech. Ageing Dev. | pmid:6330462 |
| Sakaguchi M et al. | Effect of dietary unsaturated and saturated fats on azoxymethane-induced colon carcinogenesis in rats. | 1984 | Cancer Res. | pmid:6704963 |
| Benaim G et al. | Different conformational states of the purified Ca2+-ATPase of the erythrocyte plasma membrane revealed by controlled trypsin proteolysis. | 1984 | J. Biol. Chem. | pmid:6234313 |
| Narce M and Poisson JP | [In vitro study of delta 6- and delta 5-desaturations of linoleic and dihomo-gamma-linolenic acids during the development of arterial hypertension as a function of age in spontaneously hypertensive rats (SHR) as compared to normotensive rats (WKY)]. | 1984 | C. R. Seances Soc. Biol. Fil. | pmid:6241017 |
| Naegelen J et al. | [Placental fatty acids in the guinea pig during pregnancy]. | 1984 | C. R. Seances Soc. Biol. Fil. | pmid:6241019 |
| Sanders TA et al. | The influence of a maternal diet rich in linoleic acid on brain and retinal docosahexaenoic acid in the rat. | 1984 | Br. J. Nutr. | pmid:6228249 |
| Enig MG et al. | Trans-unsaturated fatty acids in margarines and human subcutaneous fat in Israel. | 1984 | Hum Nutr Clin Nutr | pmid:6086551 |
| Baba A et al. | Modulation by unsaturated fatty acids of norepinephrine- and adenosine-induced formation of cyclic AMP in brain slices. | 1984 | J. Neurochem. | pmid:6315886 |
| Booyens J et al. | Some effects of linoleic acid and gamma-linolenic acid on the proliferation of human hepatoma cells in culture. | 1984 | S. Afr. Med. J. | pmid:6324395 |
| Kitagawa S et al. | Effects of four types of reagents on ADP-induced aggregation and Ca2+ mobilization of bovine blood platelets. | 1984 | Biochim. Biophys. Acta | pmid:6324876 |
| Simon I et al. | Electron-spin resonance studies of lipid-modified microsomes from Friend erythroleukemia cells. | 1984 | Biochim. Biophys. Acta | pmid:6326852 |
| Manku MS et al. | Essential fatty acids in the plasma phospholipids of patients with atopic eczema. | 1984 | Br. J. Dermatol. | pmid:6329254 |
| Toda S et al. | [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. | 1984 | Yakugaku Zasshi | pmid:6491877 |
| Agnoli GC et al. | [Relation between acute changes in diuresis and renal prostaglandins. I: Induced hypotonic polyuria]. | 1984 | Boll. Soc. Ital. Biol. Sper. | pmid:6497992 |
| Válek J et al. | [Linoleic acid in patients with ischemic heart disease]. | 1984 | Vnitr Lek | pmid:6506507 |
| Reeves VB et al. | Variations in plasma fatty acid concentrations during a one-year self-selected dietary intake study. | 1984 | Am. J. Clin. Nutr. | pmid:6507356 |
| Becker W | Distribution of 14C after oral administration of [1-14C]linoleic acid in rats fed different levels of essential fatty acids. | 1984 | J. Nutr. | pmid:6470826 |
| Iritani N et al. | Physiological impairment in linoleic acid deficiency of rats and the effect of n-3 polyunsaturated fatty acids. | 1984 | J. Nutr. Sci. Vitaminol. | pmid:6470835 |
| Rogiers V et al. | Abnormal fatty acid turnover in the phospholipids of the red blood cell membranes of cystic fibrosis patients (in vitro study). | 1984 | Pediatr. Res. | pmid:6472942 |
| Neufeld EJ et al. | A mutant HSDM1C1 fibrosarcoma line selected for defective eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase. | 1984 | J. Biol. Chem. | pmid:6420417 |
| Noble RC et al. | Lipid composition of the bovine epidermis. | 1984 | Res. Vet. Sci. | pmid:6473909 |
| Tseng YL and Latham KR | Iodothyronines: oxidative deiodination by hemoglobin and inhibition of lipid peroxidation. | 1984 | Lipids | pmid:6708757 |
| Huang YS et al. | Effect of dietary depletion and repletion of linoleic acid on renal fatty acid composition and urinary prostaglandin excretion. | 1984 | Prostaglandins Leukot Med | pmid:6593743 |
| Margetts BM et al. | Dietary fats and blood pressure. | 1984 | Aust N Z J Med | pmid:6596055 |