Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Spirochaetales Infections D013145 2 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Starvation D013217 47 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Thrombosis D013927 49 associated lipids
Tinea Versicolor D014010 5 associated lipids
Tremor D014202 15 associated lipids
Tuberculosis D014376 20 associated lipids
Varicocele D014646 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Wounds, Penetrating D014950 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Reperfusion Injury D015427 65 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Song E et al. Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice. 2014 J Am Heart Assoc pmid:24721803
Bernhard W et al. Plasma phospholipids indicate impaired fatty acid homeostasis in preterm infants. 2014 Eur J Nutr pmid:24464176
Xu QY et al. Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. 2014 Acta Pharmacol. Sin. pmid:25220639
Victoria FN et al. Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal. 2014 Eur. J. Pharmacol. pmid:25218989
Farvid MS et al. Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies. 2014 Circulation pmid:25161045
Harris WS and Shearer GC Omega-6 fatty acids and cardiovascular disease: friend, not foe? 2014 Circulation pmid:25161044
Saito HE et al. Incorporation of exogenous fatty acids protects Enterococcus faecalis from membrane-damaging agents. 2014 Appl. Environ. Microbiol. pmid:25128342
Wu JH et al. Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study. 2014 Circulation pmid:25124495
Spartano NL et al. Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. 2014 Lipids pmid:24595513
Scalerandi MV et al. Effect of conjugated linoleic acid mixtures and different edible oils in body composition and lipid regulation in mice. 2014 Nutr Hosp pmid:24559004
Asselin C et al. Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure. 2014 Redox Biol pmid:24494189
Mouradian M et al. Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. 2014 Prostaglandins Leukot. Essent. Fatty Acids pmid:24374147
Choi JI et al. Development of microalga Scenedesmus dimorphus mutant with higher lipid content by radiation breeding. 2014 Bioprocess Biosyst Eng pmid:24871276
Guo HH et al. XsFAD2 gene encodes the enzyme responsible for the high linoleic acid content in oil accumulated in Xanthoceras sorbifolia seeds. 2014 J. Sci. Food Agric. pmid:23775588
Bonferoni MC et al. Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. 2014 Eur J Pharm Biopharm pmid:24384070
Chevrot M et al. Obesity interferes with the orosensory detection of long-chain fatty acids in humans. 2014 Am. J. Clin. Nutr. pmid:24522446
Barua P et al. Seed oils from non-conventional sources in north-east India: potential feedstock for production of biodiesel. 2014 Nat. Prod. Res. pmid:24483850
Cho Y et al. Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. 2014 Exp. Biol. Med. (Maywood) pmid:24495951
Matthaus B and Özcan MM Fatty acid and tocopherol contents of several soybean oils. 2014 Nat. Prod. Res. pmid:24499198
Paulsen SJ et al. Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. 2014 PLoS ONE pmid:24520357