Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Spirochaetales Infections D013145 2 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Starvation D013217 47 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Thrombosis D013927 49 associated lipids
Tinea Versicolor D014010 5 associated lipids
Tremor D014202 15 associated lipids
Tuberculosis D014376 20 associated lipids
Varicocele D014646 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Wounds, Penetrating D014950 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Reperfusion Injury D015427 65 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Johnson GH and Fritsche K Effect of dietary linoleic acid on markers of inflammation in healthy persons: a systematic review of randomized controlled trials. 2012 J Acad Nutr Diet pmid:22889633
Chiou TY et al. Extraction of defatted rice bran with subcritical aqueous acetone. 2012 Biosci. Biotechnol. Biochem. pmid:22878207
Ross GR et al. Fatty acid profile of pig meat after probiotic administration. 2012 J. Agric. Food Chem. pmid:22506842
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Bonacci G et al. Conjugated linoleic acid is a preferential substrate for fatty acid nitration. 2012 J. Biol. Chem. pmid:23144452
Gutla PV et al. Modulation of plant TPC channels by polyunsaturated fatty acids. 2012 J. Exp. Bot. pmid:23105130
Saei-Dehkordi SS et al. Chemical composition and antioxidative activity of Echinophora platyloba DC. essential oil, and its interaction with natural antimicrobials against food-borne pathogens and spoilage organisms. 2012 J. Food Sci. pmid:23106123
Rohr-Udilova N et al. Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. 2012 Hepatology pmid:22105228
Smith AN et al. Unsaturated fatty acids induce mesenchymal stem cells to increase secretion of angiogenic mediators. 2012 J. Cell. Physiol. pmid:22105830
Ozcan MM et al. Characteristics of grape seed and oil from nine Turkish cultivars. 2012 Nat. Prod. Res. pmid:22132714
Jung CH et al. The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells. 2012 Inflammation pmid:22124782
Little JP et al. The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation. 2012 J. Alzheimers Dis. pmid:22045487
Cortie CH and Else PL Dietary docosahexaenoic Acid (22:6) incorporates into cardiolipin at the expense of linoleic Acid (18:2): analysis and potential implications. 2012 Int J Mol Sci pmid:23203135
Martorell P et al. Caenorhabditis elegans as a model to study the effectiveness and metabolic targets of dietary supplements used for obesity treatment: the specific case of a conjugated linoleic acid mixture (Tonalin). 2012 J. Agric. Food Chem. pmid:23072574
Hu ZP et al. Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. 2012 J. Proteome Res. pmid:23078235
Celia C et al. Ethosomes® and transfersomes® containing linoleic acid: physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. 2012 Biomed Microdevices pmid:21960035
Kanter JE et al. Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages. 2012 Biochim. Biophys. Acta pmid:22020260
Saracoglu HT et al. Evaluation of oil content and fatty acid composition of five endemic Bupleurum species growing in the Central Anatolia region of Turkey. 2012 Nat. Prod. Res. pmid:21870933
Lee S et al. Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1. 2012 Br. J. Nutr. pmid:21846428
de Goede J et al. Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20,000 middle-aged men and women in the Netherlands. 2012 Br. J. Nutr. pmid:21816117
Matesanz N et al. Linoleic acid increases monocyte chemotaxis and adhesion to human aortic endothelial cells through protein kinase C- and cyclooxygenase-2-dependent mechanisms. 2012 J. Nutr. Biochem. pmid:21840193
Dubey V et al. Appraisal of conjugated linoleic acid production by probiotic potential of Pediococcus spp. GS4. 2012 Appl. Biochem. Biotechnol. pmid:22971829
Florence AC et al. Fatty acid profile, trans-octadecenoic, α-linolenic and conjugated linoleic acid contents differing in certified organic and conventional probiotic fermented milks. 2012 Food Chem pmid:22980792
Rasic-Milutinovic Z et al. Lower serum paraoxonase-1 activity is related to linoleic and docosahexanoic fatty acids in type 2 diabetic patients. 2012 Arch. Med. Res. pmid:22222492
Regensburger J et al. Fatty acids and vitamins generate singlet oxygen under UVB irradiation. 2012 Exp. Dermatol. pmid:22229443
Gursoy O et al. The effect of using different probiotic cultures on conjugated linoleic acid (CLA) concentration and fatty acid composition of white pickle cheese. 2012 Int J Food Sci Nutr pmid:22166042
Padilla MN et al. Molecular cloning, functional characterization and transcriptional regulation of a 9-lipoxygenase gene from olive. 2012 Phytochemistry pmid:22169502
Levitan EB et al. α-Linolenic acid, linoleic acid and heart failure in women. 2012 Br. J. Nutr. pmid:22172525
Beevi SS et al. Polyphenolics profile and antioxidant properties of Raphanus sativus L. 2012 Nat. Prod. Res. pmid:21714734
Zengin G et al. Composition of essential oil and antioxidant capacity of Centaurea drabifolia Sm. subsp. detonsa (Bornm.) Wagenitz, endemic to Turkey. 2012 Nat. Prod. Res. pmid:21714737
Sajid ZI et al. Antioxidant, antimicrobial properties and phenolics of different solvent extracts from bark, leaves and seeds of Pongamia pinnata (L.) Pierre. 2012 Molecules pmid:22466852
Shindo T et al. Effective induction of oral anaphylaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate. 2012 J Toxicol Sci pmid:22467021
Shimomoto T et al. Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet. 2012 J. Gastroenterol. pmid:22467055
Pestana JM et al. Effect of slaughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers, and nutritional value of intramuscular fat in organic beef. 2012 J. Sci. Food Agric. pmid:22473659
Kuipers RS et al. Gestational age dependent changes of the fetal brain, liver and adipose tissue fatty acid compositions in a population with high fish intakes. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22425685
Zein CO et al. Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism. 2012 Hepatology pmid:22505276
Martínez Marín AL et al. Effects of feeding increasing dietary levels of high oleic or regular sunflower or linseed oil on fatty acid profile of goat milk. 2012 J. Dairy Sci. pmid:22459841
Maqbool A et al. Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22699835
da Silva Acosta D et al. Fullerene and omega-3 and omega-6 fatty acids on fish brain antioxidant status. 2012 Fish Physiol. Biochem. pmid:22451341
Li D et al. Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings. 2012 Int J Nanomedicine pmid:23269869
Roongpisuthipong W et al. Essential fatty acid deficiency while a patient receiving fat regimen total parenteral nutrition. 2012 BMJ Case Rep pmid:22707694
Ren HT et al. Influence of dietary fatty acids on muscle fatty acid composition and expression levels of Δ6 desaturase-like and Elovl5-like elongase in common carp (Cyprinus carpio var. Jian). 2012 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:22677415
Monteiro J et al. Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. 2012 Lipids Health Dis pmid:22642787
Yu T et al. Activation of oral trigeminal neurons by fatty acids is dependent upon intracellular calcium. 2012 Pflugers Arch. pmid:22644615
de Sousa Ferreira Soares G et al. Spectroscopic and thermooxidative analysis of organic okra oil and seeds from Abelmoschus esculentus. 2012 ScientificWorldJournal pmid:22645459
Wiebe MG et al. Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates. 2012 BMC Biotechnol. pmid:22646156
Angell RJ et al. Fish oil supplementation maintains adequate plasma arachidonate in cats, but similar amounts of vegetable oils lead to dietary arachidonate deficiency from nutrient dilution. 2012 Nutr Res pmid:22652378
Itakura H et al. The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid. 2012 J. Atheroscler. Thromb. pmid:22653220
Das R et al. Preparation of linoleic acid-capped silver nanoparticles and their antimicrobial effect. 2012 IET Nanobiotechnol pmid:22559712
Lasa A et al. The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. 2011 Sep-Oct Nutr Hosp pmid:22072344
Okui T et al. Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. 2011 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:21723718
Mujtaba SF et al. Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities. 2011 Sep-Oct Photochem. Photobiol. pmid:21668866
Ramandi NF et al. Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. 2011 Nov-Dec J. Food Sci. pmid:22416687
Olszewska MA Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. 2011 Nov-Dec Acta Pol Pharm pmid:22125960
Olszewska MA In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. 2011 Nov-Dec Acta Pol Pharm pmid:22125961
Kezutyte T et al. Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. 2011 Nov-Dec Acta Pol Pharm pmid:22125963
China R et al. In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. 2011 Nov-Dec J. Food Sci. pmid:22416691
Permiakova MD and Trufanov VA [Effect of soybean lipoxygenae on baking properties of wheat flour]. 2011 May-Jun Prikl. Biokhim. Mikrobiol. pmid:21790037
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Lam YY et al. Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. 2011 Jul-Aug Biochim. Biophys. Acta pmid:21570480
de Luis DA et al. Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients. 2011 Jul-Aug Nutr Hosp pmid:22470031
Aluf Y et al. Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. 2011 Jul-Aug Neuropharmacology pmid:21414328
Kang J et al. Identification of three genes encoding microsomal oleate desaturases (FAD2) from the oilseed crop Camelina sativa. 2011 Plant Physiol. Biochem. pmid:21215650
Jump DB et al. Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation. 2011 Biochem. Pharmacol. pmid:21184748
Penumetcha M et al. Modulation of leptin levels by oxidized linoleic acid: a connection to atherosclerosis? 2011 J Med Food pmid:21186986
Andreu I et al. Probing lipid peroxidation by using linoleic acid and benzophenone. 2011 Chemistry pmid:21793062
Shibata H et al. Effect of supplementation of soy sauce oil and Ca salts of fatty acids on rumen fermentation, milk production and conjugated linoleic acid in milk of dairy cows. 2011 Anim. Sci. J. pmid:21794014
Royan M et al. Effects of conjugated linoleic acid, fish oil and soybean oil on PPARs (α & γ) mRNA expression in broiler chickens and their relation to body fat deposits. 2011 Int J Mol Sci pmid:22272093
Prasad A and Pospíšil P Linoleic acid-induced ultra-weak photon emission from Chlamydomonas reinhardtii as a tool for monitoring of lipid peroxidation in the cell membranes. 2011 PLoS ONE pmid:21799835
Salleh WM et al. Chemical compositions, antioxidant and antimicrobial activities of essential oils of Piper caninum Blume. 2011 Int J Mol Sci pmid:22174627
Li YC et al. Effects of conjugated linoleic acid on cleavage of amyloid precursor protein via PPARγ. 2011 Neurol. Sci. pmid:21800078
Baâtour O et al. Salt effects on Origanum majorana fatty acid and essential oil composition. 2011 J. Sci. Food Agric. pmid:21800320
Toledo L et al. Substrate binding to mammalian 15-lipoxygenase. 2011 J. Comput. Aided Mol. Des. pmid:21861154
Vedtofte MS et al. Dietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease. 2011 Am. J. Clin. Nutr. pmid:21865326
Amtul Z et al. Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids. 2011 J. Neurosci. Res. pmid:21748777
Bowden JA et al. Electrospray ionization tandem mass spectrometry of sodiated adducts of cholesteryl esters. 2011 Lipids pmid:21904795
Shchepinov MS et al. Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease. 2011 Toxicol. Lett. pmid:21906664
Aktumsek A et al. Screening for in vitro antioxidant properties and fatty acid profiles of five Centaurea L. species from Turkey flora. 2011 Food Chem. Toxicol. pmid:21878362
Guesnet P et al. α-Linolenate reduces the dietary requirement for linoleate in the growing rat. 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:21880475
Dailey MJ et al. Jejunal linoleic acid infusions require GLP-1 receptor signaling to inhibit food intake: implications for the effectiveness of Roux-en-Y gastric bypass. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21917638
Lee YJ and Jenkins TC Identification of enriched conjugated linoleic acid isomers in cultures of ruminal microorganisms after dosing with 1-(13)C-linoleic acid. 2011 J. Microbiol. pmid:21887646
Zhou XR et al. Caenorhabditis elegans Delta12-desaturase FAT-2 is a bifunctional desaturase able to desaturate a diverse range of fatty acid substrates at the Delta12 and Delta15 positions. 2011 J. Biol. Chem. pmid:22041902
Ogawa E et al. Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway. 2011 J. Invest. Dermatol. pmid:21068754
Odabasoglu F et al. α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations. 2011 Br. J. Nutr. pmid:21073761
Akrout A et al. Antioxidant and antitumor activities of Artemisia campestris and Thymelaea hirsuta from southern Tunisia. 2011 Food Chem. Toxicol. pmid:21075159
Vinaixa M et al. Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. 2011 PLoS ONE pmid:22194988
Narwaley M et al. Drug-induced protein free radical formation is attenuated by unsaturated fatty acids by scavenging drug-derived phenyl radical metabolites. 2011 Chem. Res. Toxicol. pmid:21671642
Göçer H and Gülçin I Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties. 2011 Int J Food Sci Nutr pmid:21631390
Lautenslager GT et al. Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin. 2011 Metab. Clin. Exp. pmid:21632076
Blaul B and Ruther J How parasitoid females produce sexy sons: a causal link between oviposition preference, dietary lipids and mate choice in Nasonia. 2011 Proc. Biol. Sci. pmid:21429922
Sala-Vila A et al. Inverse association between serum phospholipid oleic acid and insulin resistance in subjects with primary dyslipidaemia. 2011 Clin Nutr pmid:21458117
Li M et al. Isolation of a novel C18-Δ9 polyunsaturated fatty acid specific elongase gene from DHA-producing Isochrysis galbana H29 and its use for the reconstitution of the alternative Δ8 pathway in Saccharomyces cerevisiae. 2011 Biotechnol. Lett. pmid:21538137
Ueda Y et al. Effect of dietary lipids on longevity and memory in the SAMP8 mice. 2011 J. Nutr. Sci. Vitaminol. pmid:21512289
Pi F et al. Solid-state low temperature→middle temperature phase transition of linoleic acid studied by FTIR spectroscopy. 2011 J Phys Chem B pmid:21520953
Hasegawa T et al. Constituents of the green tea seeds of Camellia sinensis. 2011 Nat Prod Commun pmid:21485277
Atri MS et al. Structure and stability analysis of cytotoxic complex of camel α-lactalbumin and unsaturated fatty acids produced at high temperature. 2011 J. Biomol. Struct. Dyn. pmid:21469752
Carrillo C et al. Oleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes. 2011 Cell. Physiol. Biochem. pmid:21471726
Wong WT et al. Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta. 2011 Nutr Metab Cardiovasc Dis pmid:20005687
Tuo Y et al. Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways. 2011 Endocrine pmid:21161439
Hamberg M Stereochemistry of hydrogen removal during oxygenation of linoleic acid by singlet oxygen and synthesis of 11(S)-deuterium-labeled linoleic acid. 2011 Lipids pmid:21161604